@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0088: (2016-03-12 )
MNDMLISLVIPVFALLVIGGIIWVIIEGIVHISKKNKAIDNFLNQVNKVSETYKFATAFLFLILATAGISQFYLYYIVSAFLFWLVILTFGIAGIIFLMPYGLCFLPLYKQKKKKQTFKKYMVYTTIGLSICLGLSLVLVHTTKIYMDEGGVRYYYGSFVMKQAGGYAYLALAVLSTLLIVAKKATNKNKEIETVDNTNITER
Atome Classification :
(16 SA)
----------.........10....-----....20----.......--------..30.....----------...-----40........-50---------..-----------..--.....60..--------------------......70-.........80---------......----..90...----..--..--.100....--...110....---...120------.-...--....130.......140.......-150--------.....----..---160..------....-----------.170...-----------.....180.......190.......200.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MN
D
M
L
I
S
L
V
I
P
V
F
A
L
-----
L
V
I
G
G
-----
I
I
W
V
I
I
E
--------
G
I
V
H
ISKK
N
----------
K
A
I
-----
D
N
F
L
N
Q
V
N
K
V
-
S
----------
E
T
-----------
Y
K
--
F
A
T
A
F
L
F
L
I
--------------------
L
A
T
A
G
I
S
--
Q
F
Y
L
Y
Y
I
V
S
A
F
---------
L
F
W
L
V
I
----
L
T
F
G
I
A
G
----
I
I
--
F
L
--
M
P
Y
G
L
C
F
L
--
P
L
Y
K
Q
K
K
K
K
Q
---
T
F
K
K
Y
-------
M
-
V
Y
T
--
T
I
G
L
S
I
C
L
G
L
S
L
V
L
V
H
T
T
K
I
Y
MDE-G
G
V
--------
R
Y
Y
Y
G
----
S
F
---
V
M
K
QA------G
G
Y
A
-----------
Y
L
A
-
L
A
V
-----------
L
S
T
L
L
I
V
A
KKATNKNK
E
I
E
TVDNTNITER-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
73.77
24%
-114
- C2 -
3GN6
6
?
A:
[22-321]
---FNPWT
D
A
A
L
D
T
I
V
N
Q
A
L
T
L
Y
A
E
M
----
R
V
V
P
A
-----
H
H
D
A
F
L
A
--------
A
I
D
T
V
S
A
K
L
----------
R
V
L
-----
P
G
F
L
S
L
A
L
K
Q
M
S
GDSTMVKNYP
E
T
-----------
Y
K
GV
L
A
T
A
Y
L
D
G
V
A
A
GTQ
P
Y
F
Y
N
L
F
V
R
F
AD
G
R
A
A
R
A
A
G
F
E
--
A
L
F
E
T
H
I
H
P
L
L
HAMADGPEL
L
A
Y
R
A
V
----
L
Q
S
V
V
A
G
D
RH
A
I
Y
--
R
G
--
A
E
E
I
R
S
F
L
R
R
P
V
E
L
P
E
R
E
T
V
---
T
V
E
N
H
-------
V
M
V
P
E
DK
H
A
A
W
E
P
Q
V
A
I
L
L
Q
V
A
Q
D
T
F
E
P
Q
D
E
P
S
G
V
G
L
P
G
A
RDN
R
Y
Y
R
K
----
A
L
S
T
E
I
L
R
N
A
HAD---
G
G
L
R
-----------
A
Y
I
M
H
G
V
W
ES
V
W
D
H
E
N
S
H
L
D
P
R
F
L
A
A
A
G
P
V
G
A
A
A
V
V
G
P
V
E
P
F
Y
L
T
R
R
L
V
V
A
D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
68.24
16%
-141
- C3 -
3JA7
-
?
A:
[1-447]
N
W
I
S
E
L
I
D
T
Y
R
N
L
M
N
N
Y
E
V
D
N
A
V
S
E
-----
I
V
S
D
A
-----
I
V
Y
E
D
D
T
--------
E
V
V
A
L
N
L
D
K
----------
S
K
---------
F
S
P
K
I
K
N
-
M
----------
M
L
-----------
D
E
--
F
S
D
V
L
N
H
L
S
--------------------
F
Q
R
K
G
S
D
--
H
F
R
R
W
Y
V
D
S
R
I
---------
F
F
H
K
I
I
D
PKR
P
K
E
G
I
K
E
----
L
R
--
R
L
--
D
P
R
Q
V
Q
Y
V
--
Y
F
I
Y
D
T
A
H
E
S
YAC
D
G
R
M
Y
-------
E
-
A
G
T
--
K
I
K
I
P
---
K
A
A
V
V
Y
A
H
S
G
L
V
D
C
C
G
-
K
N
I
--------
I
G
Y
L
-------------
H
R
------
A
V
K
P
-----------
A
N
Q
-
L
K
L
-----------
L
E
D
A
V
V
I
Y
R
I
T
R
A
P
D
R
R
V
W
Y
V
D
T
G
N
M
P
A
R
K
A
A
E
H
M
Q
H
V
M
N
T
MKNR
V
V
Y
D
ASTGKIKNQQHNMSM
T
E
D
Y
W
L
Q
RRDGKAV
T
E
V
D
T
L
P
GADNTGNME
D
I
R
W
F
R
Q
A
L
Y
M
A
L
RVPLSRIPQDQQGGVMFDSGTSIT
R
D
E
L
T
F
A
K
F
I
R
E
L
Q
H
K
F
E
E
V
F
L
D
P
L
K
T
N
L
L
L
K
GIIT
E
D
E
W
N
D
E
I
NNI
K
I
E
F
H
RD
S
Y
F
A
E
L
K
E
A
E
I
L
E
R
R
I
N
M
L
T
M
A
EPFIGKYIS
H
R
T
A
M
K
DILQMT
D
E
E
I
E
Q
E
A
K
Q
I
E
EESKEARFQD
20
Fugue
61.02
9%
-134
- C1 -
1K6D
1
ATOD_ECOLI
A:
[1-219]
----------
M
K
T
K
L
M
T
L
Q
D
A
T
G
F
F
RDG
M
T
I
M
V
G
G
F
MGIG
T
P
S
R
L
V
E
--------
A
L
L
E
S
G
V
R
D
----------
L
T
L
I
A
NDT
A
F
V
D
T
G
I
G
P
L
-
I
----------
V
N
-----------
G
R
--
V
R
K
V
I
A
S
H
I
--------------------
G
T
N
P
E
T
G
--
R
R
M
I
S
G
E
M
D
V
V
---------
L
V
P
Q
G
T
----
L
I
E
Q
I
R
C
----
G
G
--
A
G
--
L
G
G
F
L
T
P
T
--
G
V
G
T
V
E
G
K
Q
T
---
L
T
L
D
G
-------
K
-
T
W
L
--
L
E
R
P
---
L
R
A
D
L
A
L
I
R
A
H
R
C
D
T
L
-----------------
G
----
N
L
---
T
Y
Q
L
S
------
A
R
N
F
-----------
N
P
L
-
I
A
L
-----------
A
A
D
I
T
L
V
E
P
D
E
L
V
E
T
G
E
L
Q
P
D
H
I
V
T
P
G
A
V
IDHIIVSQES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
59.36
22%
-144
- C4 -
2ZJS
1
SECY_THET8
Y:
[77-176]
------------------
I
M
P
Y
I
T
A
-----
A
I
I
M
Q
-----
I
L
V
T
V
V
P
--------
A
L
E
K
L
S
K
E
G
----------
E
E
G
-----
R
R
I
I
N
Q
Y
T
R
I
-
G
----------
G
I
-----------
A
L
--
G
A
F
Q
G
F
F
L
A
--------------------
T
A
F
L
G
A
E
GG
R
F
L
L
P
G
W
S
P
G
P
---------
F
F
W
F
V
V
----
V
V
T
Q
V
A
G
----
I
A
--
L
L
--
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
59.06
14%
-139
- C4 -
3UM7
4
KCNK4_HUMAN
A:
[25-290]
-------RAM
R
S
T
T
L
L
A
L
L
A
L
V
L
L
Y
-----
L
V
S
G
A
-----
L
V
F
R
A
L
E
QPHEQQA
Q
R
E
L
G
E
V
R
E
K
F
L
R
A
HPCVS
D
Q
E
L
-----
G
L
L
I
K
E
V
A
D
A
-
L
----------
G
G
GADPETQSTSA
W
D
--
L
G
S
A
F
F
F
S
G
--------------------
T
I
I
T
T
I
G
Y-
G
N
V
A
L
R
T
D
A
G
R
---------
L
F
C
I
F
Y
----
A
L
V
G
I
P
L
----
F
G
--
I
L
--
L
A
G
V
G
D
R
L
--
G
S
S
L
R
H
G
I
G
H
---
I
E
A
I
F
L
K
W
HP
E
L
V
-
R
V
L
--
S
A
M
L
F
L
L
I
G
C
L
L
F
V
L
T
P
T
F
V
F
C
Y
M
-
E
D
W
--------
S
K
L
E
A
----
I
Y
---
F
V
I
V
T
L
T
TVGF
G
D
Y
V
AGADPRQDSPA
Y
Q
P
-
L
V
W
-----------
F
W
I
L
L
G
L
A
Y
F
A
S
V
L
T
T
I
G
N
W
L
R
V
V
S
R
R
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
55.82
11%
-109
* C3 *
4HKR
3
CRCM1_DROME
A:
[12-202]
-----------------------------------------------------------
T
Y
L
S
W
----------
R
K
L
-----
Q
L
S
R
A
K
L
K
A
S
-
S
----------
K
T
-----------
S
A
--
L
L
S
G
F
A
M
V
A
--------------------
M
V
E
V
Q
M
----
L
I
A
F
A
I
C
T
T
L
---------
L
V
A
V
H
M
----
L
A
L
M
I
S
T
----
C
I
-------------
L
--
P
N
P
H
E
R
L
H
W
Y
---
I
E
T
A
W
-------
A
-
F
S
T
--
L
L
G
L
I
L
F
L
L
E
I
A
I
L
C
W
V
K
F
Y
D
L
S
R
-
R
A
A
--------
W
S
A
T
V
V
L
I
P
V
M
---
I
I
F
M
A
------
F
A
I
H
-----------
F
Y
R
-
S
L
V
-----------
S
H
K
Y
E
V
T
V
S
G
I
R
E
L
E
M
L
K
E
Q
M
E
Q
D
H
L
E
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
51.57
22%
-138
- C4 -
2ZQP
-
SECY_THET8
Y:
[77-176]
------------------
I
M
P
Y
I
T
A
-----
A
I
I
M
Q
-----
I
L
V
T
V
V
P
--------
A
L
E
K
L
S
K
E
G
----------
E
E
G
-----
R
R
I
I
N
Q
Y
T
R
I
-
G
----------
G
I
-----------
A
L
--
G
A
F
Q
G
F
F
L
A
--------------------
T
A
F
L
G
A
E
GG
R
F
L
L
P
G
W
S
P
G
P
---------
F
F
W
F
V
V
----
V
V
T
Q
V
A
G
----
I
A
--
L
L
--
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
33.97
13%
-91
- C4 -
2K1A
-
ITA2B_HUMAN
A:
[966-998]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
W
W
V
L
----
V
G
V
-
L
G
G
----
L
L
L
L
T
I
--
L
V
L
A
M
W
K
V
--
G
F
F
K
R
N
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
33.94
15%
-75
- C4 -
2KNC
-
ITA2B_HUMAN
A:
[966-1000]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
W
W
V
L
----
V
G
V
-
L
G
G
----
L
L
--
L
L
T
I
L
V
L
A
M
W
K
V
--
G
F
F
K
R
N
R
P
P
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
32.62
21%
-36
- C4 -
2L8S
-
A:
[9-43]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
V
I
L
----
L
S
A
F
A
G
L
L
---
L
L
--
M
L
--
L
I
L
A
L
W
K
I
--
G
F
F
K
R
P
L
K
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.64
22%
-66
- C4 -
2LFC
-
?
A:
[22-58]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
Y
V
N
S
K
G
D
R
I
V
N
E
-
S
N
V
--------
Y
T
T
F
R
----
N
A
---
I
L
K
Q
A
------
D
K
V
A
-----------
Y
L
V
-
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
22.87
21%
236
- C4 -
4GEQ
-
F:
[2-20]
-------------------------------------------------------------
K
D
P
----------
N
E
V
-----
R
S
F
L
Q
D
L
S
Q
V
-
L
----------
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
19.25
24%
84
- C4 -
2W0C
-
P6_BPPM2
T:
[12-45]
------------------------
I
-----
L
A
A
G
V
-----
G
V
W
F
Y
-----------------------------
Q
K
A
-----
D
N
A
A
K
T
A
T
K
--------------
P
-----------
I
A
--
D
F
L
A
E
L
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
16.08
21%
108
- C4 -
1PSM
-
?
A:
[1-38]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
Y
-----------
K
K
A
-
K
Q
A
-----------
S
Q
D
A
E
Q
A
A
K
D
A
E
N
A
S
K
E
A
E
E
A
A
K
E
A
V
N
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
16.08
21%
108
* C4 *
1PSM
-
?
?:
[1-38]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
Y
-----------
K
K
A
-
K
Q
A
-----------
S
Q
D
A
E
Q
A
A
K
D
A
E
N
A
S
K
E
A
E
E
A
A
K
E
A
V
N
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
13.70
22%
164
- C4 -
2RDD
-
YAJC_ECOLI
B:
[12-34]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
--
G
L
--
I
F
Y
F
M
I
L
R
--
P
Q
Q
K
R
T
K
E
H
K
---
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------