@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0124: (2016-03-12 )
MKKLQLKKWKCRENDIEAVHNNKGYAYQRKLDALEEVRKGYYPIKRAIDLVLSIVLLFLTFPIMFIFAIAIVIDSPGNPIYSQVRVGKMGKLIKIYKLRSMCKNAEKNGAQWADKDDDRITNVGKFIRKTRIDELPQLINVVKGEMSFIGPRPERPEFVELFSSEVIGFEQRCLVTPGLTGLAQIQGGYDLTPQQKLKYDMKYIHKGSLMMELYISIRTLMVVITGEGSR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------.........10........20..-------......30........40..----....-----..50...-------.....60........70........80........90.......--------.100.......110.......120....-...130-----........140.---......--150......--.160.....--..170-.....-..180--.-----.------.....190-----.......200....-----...210...-....-----220.......230--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------MKKLQLKKWKCREND
I
E
A
VHNNK-------G
Y
A
Y
Q
R
K
L
D
A
L
E
E
V
R
KGY
Y
P
----
I
K
R
A
-----
I
D
L
V
L
S
I
-------
V
L
L
F
L
T
F
P
I
M
F
I
F
A
I
A
I
V
IDSPGN
P
I
Y
S
Q
V
RVGKM
G
K
L
I
K
I
Y
K
L
--------
R
S
M
C
KNAEKNGAQWADKDDD
R
I
T
N
V
G
K
F
-
I
R
K
T
R
------
I
D
E
L
P
Q
L
I
N
V
V
K---G
E
M
SFI--GPRPER
P
E
F
--
V
E
L
F
S
S
E
VI--GF
E
Q
R
-
C
LVTP-GL
T
G
L
--
A
-----
Q
------IQGGYDL
T
-----
P
Q
Q
K
L
K
Y
D
M
K
Y
I
HK-----G
S
L
M
M
E
L
Y
I
-
S
I
R
T
-----
L
M
V
V
I
TGEGSR----------------------------------------
15
Fugue
92.94
19%
-89
- C4 -
4PCA
4
?
A:
[6-226]
-----------------------------------------------------------------------------------------------------------------H
H
H
M
R
N
V
S
L
S
K
Q
D
E
Y
L
N
K
L
F
A
V
D
T
E
G
-------
A
L
K
A
H
K
--
T
A
P
S
E
L
R
M
A
Q
L
G
----
T
V
E
G
-----
Q
M
L
Q
L
L
I
R
M
A
GIH
S
I
V
E
V
G
T
C
V
G
F
S
A
I
C
M
A
H
A
L
P
S
K
G
-------------
H
I
Y
T
I
E
K
D
--------
Y
E
N
V
V
T
A
N
Q
N
I
V
N
C
--
K
L
E
D
K
I
T
----
V
-
L
H
G
E
A
------
L
A
Q
L
N
T
L
K
E
M
A
P
---
F
D
M
I
F
I
--
D
A
N
--
K
S
S
Y
--
L
A
Y
L
N
W
A
K
M
--
Y
I
R
K
G
-
G
L
I
V
A
-
D
N
T
F
L
FG
S
-----
V
------
F
D
E
H
P
T
E
K
-----
V
S
S
N
A
H
A
S
M
R
A
F
N
D
-----
E
L
A
N
K
E
K
Y
L
-
S
T
I
I
PTSE
G
M
M
V
S
I
K
L
T
-------------------------------------------
19
Fugue
83.57
13%
-55
- C4 -
5CPC
-
?
A:
[30-317]
-------------------------------------------------------------------------------------------------------------K
A
I
H
M
GG
W
D
K
V
Q
D
H
F
R
A
E
K
K
D
H
A
L
E
V
L
H
S
I
I
HGEMEV
N
V
E
D
I
N
K
I
Y
A
F
K
R
L
Q
H
L
A
C
P
----
A
H
Q
D
L
F
T
I
K
M
D
A
S
Q
T
Q
-------
F
L
L
M
V
G
D
T
V
I
S
Q
S
N
I
K
D
I
L
N
I
S
D
D
A
V
I
E
S
M
S
R
E
E
R
Q
L
F
L
Q
I
C
E
V
I
G
S
K
M
T
WH
P
E
L
L
Q
E
S
I
S
T
L
R
K
E
V
T
G
N
A
Q
I
K
T
A
V
Y
E
M
-
M
R
P
A
E
APDHPL
V
E
W
Q
D
S
L
T
A
D
E
K
---
S
M
L
A
C
I
NA
G
N
F
E
P
T
T
Q
F
--
C
K
I
G
Y
Q
E
V
Q
--
G
E
V
A
F
-
S
M
M
H
P
-
C
I
S
Y
L
--
L
-----
H
SYSPFS
E
F
K
P
T
N
S
G
-----
F
L
K
K
L
N
Q
D
Y
N
D
Y
H
A
K
K
M
F
I
D
V
I
L
E
K
L
Y
L
-
T
H
E
R
-----
S
L
H
I
G
K
D
G
C
S
R
NILLT-----------------------------------
18
Fugue
72.36
15%
-46
- C4 -
4O5J
3
?
A:
[27-400]
LKN
L
N
E
K
Y
E
Q
L
S
Q
Y
L
N
Q
V
A
S
L
K
Q
S
I
Q
N
A
N
N
I
E
L
V
N
S
S
L
N
Y
L
K
S
F
T
N
N
N
Y
NSTTQS
P
I
F
N
A
V
Q
A
V
I
T
S
V
L
G
F
W
S
L
Y
AGNYFTFFVGKKVD
S
G
Q
P
A
SVQGNPPFKTIIENCSGIENCA
M
D
Q
T
T
Y
D
K
M
K
K
L
A
E
D
L
Q
A
A
Q
T
N
S
-------
A
T
K
-
G
N
N
L
C
A
L
S
G
C
A
A
T
S
N
P
PNST
V
S
N
A
-----
L
N
L
A
Q
Q
L
-------
M
D
L
I
A
N
T
K
T
A
M
M
W
K
N
-
I
V
I
S
G
V
S
N
T
S
G
A
I
T
S
T
N
Y
P
T
Q
Y
A
V
F
N
N
I
--------
K
A
M
I
P
I
L
Q
Q
A
V
T
L
S
Q
S
N
H
T
L
S
A
S
L
Q
A
Q
A
-
T
G
S
Q
T
------
N
P
K
F
A
K
D
I
Y
T
F
A
---
Q
N
Q
K
Q
V
----
I
S
Y
A
Q
D
I
--
F
N
L
F
N
S
--
I
--
P
A
E
Q
Y
-
K
Y
L
E
K
------------------------
A
Y
L
K
I
-----
P
N
A
G
S
T
P
T
N
P
Y
---------
R
Q
V
V
N
L
N
Q
-
E
V
Q
T
-----
I
K
N
N
V
S
Y
Y
G
N
R
V
D
A
A
L
S
V
A
R
D
V
Y
N
L
K
S
N
Q
A
E
I
V
T
A
Y
N
D
A
K
T
L
S
E
E
I
S
K
LPH
21
Fugue
55.43
22%
-8
- C2 -
4Q28
-
PEPL_HUMAN
A:
[2-111]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
H
H
H
H
H
H
S
H
M
R
------
R
S
I
V
V
I
H
P
D
T
G
R
E
L
S
P
E
E
A
H
R
A
G
L
I
D
W
N
M
F
V
K
L
R
------
S
Q
E
C
D
W
E
E
I
S
V
K
GPN
G
E
S
S
V
I
--
H
D
R
K
S
G
K
K
F
S
I
E
E
A
L
Q
S
G
R
L
T
P
A
Q
Y
D
R
-
Y
V
N
K
D
M
S
I
Q
E
L
--
A
-----
V
------
L
V
S
G
--------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
51.02
40%
-20
- C4 -
3RKO
-
?
M:
[32-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
I
T
M
-
G
L
T
-
L
--
A
LSLQL
W
------
L
Q
G
G
Y
S
L
T
QSAGI
P
Q
W
Q
S
E
F
D
M
P
W
I
P
R
-----
F
G
I
S
I
H
L
A
I
D
G
L
S
L
-----
L
M
V
V
L
T
G
--------------------------------------------
20
Fugue
46.03
34%
228
- C4 -
2X6P
1
?
A:
[4-30]
---------------------------------------------------------------------------------------------------------------------------
E
W
E
A
L
E
K
K
L
A
A
L
-
E
S
K
-------
L
Q
A
C
E
K
K
L
E
A
L
E
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
45.78
22%
30
- C4 -
2ZVI
-
MTNW_BACSU
A:
[89-139]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
I
P
A
L
L
T
T
V
F
---
G
K
L
S
L
D
G-
K
I
K
L
I
D
L
H
F
--
S
E
A
---------
F
K
R
A
L
P
G
P
K
F
-
G
V
Y
G
I
--
R
-----
K
------
L
L
G
E
--------------------------------------------------------------------------------------------------
22
Fugue
45.35
34%
163
- C4 -
1COS
2
?
A:
[1-29]
---------------------------------------------------------------------------------------------------------------------------
E
W
E
A
L
E
K
K
L
A
A
L
-
E
S
K
-------
L
Q
A
L
E
K
K
L
E
A
L
E
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.28
33%
-63
- C4 -
3QF4
-
?
A:
[160-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
I
N
V
K
L
S
S
-------
V
L
I
F
L
I
P
P
I
V
L
L
F
---
V
W
L
T
K
K
G
N
P
L
F
R
K
I
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.06
33%
-69
- C4 -
4Q4H
-
?
A:
[160-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
I
N
V
K
L
S
S
-------
V
L
I
F
L
I
P
P
I
V
L
L
F
---
V
W
L
T
K
K
G
N
P
L
F
R
K
I
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
43.81
31%
236
- C4 -
2JGO
3
?
A:
[4-29]
---------------------------------------------------------------------------------------------------------------------------
E
W
E
A
L
E
K
K
C
A
A
L
E
S
K
L
-------
Q
-
A
L
E
K
K
L
E
A
L
E
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
43.52
31%
239
* C4 *
3LJM
4
?
A:
[4-29]
---------------------------------------------------------------------------------------------------------------------------
E
W
E
A
L
E
K
K
C
A
A
L
E
S
K
L
-------
Q
-
A
L
E
K
K
L
E
A
L
E
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
43.52
33%
-54
- C4 -
4Q4J
-
?
A:
[160-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
I
N
V
K
L
S
S
-------
V
L
I
F
L
I
P
P
I
V
L
L
F
---
V
W
L
T
K
K
G
N
P
L
F
R
K
I
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
43.46
33%
-57
- C4 -
4Q4A
-
?
A:
[160-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-----
I
N
V
K
L
S
S
-------
V
L
I
F
L
I
P
P
I
V
L
L
F
---
V
W
L
T
K
K
G
N
P
L
F
R
K
I
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
40.44
44%
256
- C4 -
2JVW
-
?
A:
[44-59]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
P
S
I
K
S
S
L
K
F
-
L
R
K
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.36
14%
28
- C4 -
3FK4
-
MTNW_BACCR
A:
[87-143]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
L
P
A
I
L
T
T
T
F
---
G
K
L
S
L
D
G-
E
V
K
L
I
D
L
T
F
--
S
D
E
---------
L
K
K
H
F
P
G
P
K
F
-
G
I
D
G
I
--
R
-----
N
------
L
L
Q
V
--------------------------------------------------------------------------------------------------
6
HHSearch
38.99
36%
196
- C3 -
2E6X
-
?
A:
[27-48]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
R
V
G
L
A
-
S
A
T
P
R
------
F
R
E
L
P
R
L
L
N
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
37.49
31%
273
- C4 -
3NWR
-
?
A:
[105-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
L
P
T
L
A
A
T
V
A
---
G
N
L
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
33.98
29%
238
- C4 -
2OEM
1
MTNW_GEOKA
A:
[86-100]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
P
A
L
L
V
T
T
F
---
G
K
L
S
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
33.54
38%
225
- C4 -
3QFW
-
?
A:
[78-107]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
P
G
Q
L
L
N
M
L
F
---
G
N
S
S
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------