@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0144: (2016-03-12 )
MESTLELTKIKEVLQKNLKILIILPLLFLIISAIVTFFVLSPKYQANTQILVNQTKGDNPQFMAQEVQSNIQLVNTYKEIVKSPRILDEVSKDLNDKYSPSKLSSMLTITNQENTQLINIQVKSGHKQDSEKIANSFAKVTSKQIPKIMSVDNVSILSKADGTAVKVAPKTVVNLIGAFFLGLVVALIYIFFKVIFDKRIKDEEDVEKELGLPVLGSIQKFN
Atome Classification :
(20 SA)
-----------------------------------------------.........10........-20..--------.....-.30....----------....40.......-----.50...--------.....60..----..-----....70.---.------..-...------------.80.--------.--..-..-..90.......---------.100.......----110---..------.--..---..-.120.---------------.....--------.130-.........-----140.....-.-.150.......160...---.---...-170.......180-------....-----...-190....--...200.....------------..210---------.......220-----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------MEST
L
E
L
T
K
I
K
E
V
L
Q
KN
L
K
-
I
L
I
I
--------
L
P
L
L
F
-
L
I
I
S
A
I
V
----------
T
F
FVLSPKYQAN
T
-----
Q
I
L
V
NQ--------TKGD
N
P
Q
F
M
----
A
Q
-----
E
V
QSN
I
Q
---
L
------
V
N
-
T
Y
K
------------
E
I
V
K--------S--
P
R
-
I
L
-
D
E
V
S
K
D
LNDKY---------
S
P
S
K
L
S
S
M
L
T
I
----TN----QE------N--
T
Q
---
L
I
-
N
I
Q
V
K---------------SGHKQ--------
D
S
---
E
K
I
A
N
S
F
A
K
-----
V
T
S
K
QIP
K
-
I
-MSVD
N
V
S
I
L
SKADG
T
A
V
---
K
---V
A
P
-
K
T
V
V
N
L
I
G
A
F
F
L
G
-------
L
V
V
A
-----
L
I
Y
-
I
F
F
K
V
I
F
--
D
KRIK
D
E
E
D
V
E
------------
K
E
LGL---------PVLGSIQKFN-----------------
32
Fugue
70.60
18%
-64
- C3 -
4BFA
6
DUSC_ECOLI
A:
[22-338]
-----------------------------------------------
A
S
M
R
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
-
E
L
L
T
--------
E
V
N
D
Y
D
L
C
I
T
E
F
V
RVVDQLLP
V
K
V
F
H
R
I
C
P
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L
Q
N
A
S
RTPS
G
T
L
V
R
V
Q
--------
L
L
G
Q
F
P
Q
W
L
----
A
E
-----
N
A
A
R
A
V
E
---
L
GSW
G
V
D
L
N
-
C
G
C
P
S
K
T
V
NGSGGG
A
T
L
L
K
--------
D
--
P
E
-
L
I
-
Y
Q
G
A
K
A
M
R
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A
V
----------
P
A
H
L
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V
S
V
K
V
R
LGW
D
S
----
G
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------
K
--
K
F
---
E
I
-
A
D
A
V
Q
Q
A
GAT
E
L
V
V
HGRTKE
Q
G
Y
R
A
--------
E
H
ID
W
Q
A
I
G
D
I
R
Q
R
L
N
I
P
V
I
A
N
G
E
I
W
D
-
W
-
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
---
G
---
R
G
A
-
L
N
I
P
N
L
S
R
V
V
K
Y
N
EPRMP
W
P
E
V
V
A
-----
L
L
Q
-
K
Y
T
R
L
E
K
Q
G
D
T
G
L
Y
H
V
A
R
I
K
------------
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
IDIEKL
37
Fugue
68.23
20%
3
- C3 -
4PE6
1
?
A:
[18-339]
K
P
F
I
A
L
S
N
GFIGN
G
W
R
Q
T
M
I
A
K
F
E
E
A
A
K
Q
A
Q
A
D
GLIG
K
Y
K
V
V
N
A
P
G
N
N
S
A
T
E
Q
V
A
Q
I
K
S
L
L
L
Q
K
P
D
-
A
L
L
I
NPASPTAL
Q
P
V
I
Q
-
Q
A
C
D
A
G
V
----------
K
V
V
V
F
D
S
A
I
D
A
P
C
-----
A
Y
I
L
Q
N
--------
S
F
V
D
W
A
T
Y
A
----
A
K
-----
P
V
L
E
S
I
G
G
K
G
N
------
V
I
-
V
V
R
------------
G
V
V
G
--------
S
Q
-
P
E
-
A
E
M
Y
E
T
T
K
K
I
L
A
E
Y
---------
P
Q
V
K
T
V
A
T
V
T
G
M---
C
D
----
G
A
------
T
--
A
Q
---
K
A
-
V
L
G
V
L
---------------
P
S
V
S
T
VD
A
V
I
G
C
G
D
G
---
Y
G
V
A
Q
A
F
A
T
-----
A
-
G
K
P
I
P
A
-
V
-
T
F
E
T
N
G
R
A
L
S
Y
W
K
D
N
K
I
---
D
NG
S
V
A
V
M
S
D
P
A
Q
S
V
A
A
L
W
A
A
-------
L
D
L
L
E
G
R
D
L
P
K
Q
M
T
F
P
I
V
L
I
--
E
E
K
D
R
D
T
W
A
S
V
LKPDEYAAWPWT
R
E
L
F
R
---------
Q
Q
V
E
A
I
K
T
G
G
EPVQPPIPST-------
35
Fugue
66.38
13%
-47
- C3 -
4Y5J
-
?
A:
[15-241]
--------------------------------------------------
I
L
P
A
E
I
L
N
G
L
V
D
S
N
W
K
N
R
L
A
A
--------
V
E
Q
L
L
-
G
E
I
S
G
----------------
F
D
A
K
Q
A
G
I
S
-----
Q
I
L
I
R
T
--------
I
S
G
R
K
P
G
L
K
----
E
M
-----
N
F
Q
V
L
K
F
---
K
------
L
D
-
I
I
R
------------
S
V
A
E
N
YPLT
T
T
T
V
--
D
L
-
V
I
-
N
E
I
I
E
K
L
A
D
A
K
---------
N
G
A
A
A
A
D
V
L
S
A
----
F
A
----
E
A
------
T
K
L
E
Y
---
V
V
-
G
K
V
L
S
---------------
F
A
F
E
Q
--------
K
S
---
P
K
V
Q
S
E
A
F
N
-----
W
V
N
R
S
I
I
E
-
F
G
F
Q
L
Q
P
K
T
L
I
E
D
V
R
K
G
V
Q
STN
P
---
T
V
R
-
A
S
A
I
Q
M
V
G
T
M
S
M
Y
-------
M
G
K
A
-----
L
M
M
-
F
F
D
S
E
K
P
--
A
L
K
S
Q
I
Q
V
E
F
D
------------
K
N
V
G
E
---------
K
P
P
K
P
V
R
G
V
------------------
6
PsiBlast_PDB
48.10
30%
31
- C4 -
5CZZ
1
?
A:
[305-387]
------------------------------------------------------------------------------------------------------------------------
E
I
L
V
N
E
EDIKG
Y
R
V
T
S
T
G
K
P
E
F
T
----
N
L
-----
K
V
Y
H
D
I
K
---
D
------
I
T
-
A
R
K
------------
E
I
I
E
--------
N
--
A
E
-
L
L
-
D
Q
I
A
K
I
L
T
I
Y
Q
---------
S
S
E
D
I
Q
E
E
L
T
N
----
L
N
----
S
E
------
L
--
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
47.72
30%
28
- C4 -
5AXW
-
?
A:
[305-387]
------------------------------------------------------------------------------------------------------------------------
E
I
L
V
N
E
EDIKG
Y
R
V
T
S
T
G
K
P
E
F
T
----
N
L
-----
K
V
Y
H
D
I
K
---
D
------
I
T
-
A
R
K
------------
E
I
I
E
--------
N
--
A
E
-
L
L
-
D
Q
I
A
K
I
L
T
I
Y
Q
---------
S
S
E
D
I
Q
E
E
L
T
N
----
L
N
----
S
E
------
L
--
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.56
23%
36
- C4 -
3QNK
1
?
A:
[173-269]
----------------------------------------------------------------------------------------------------------------------------
S
R
--------
E
K
G
R
A
T
K
G
A
----
A
Y
-----
A
L
K
S
R
V
E
---
L
------
Y
D
K
R
Y
E
------------
D
V
I
K
--------
S
--
C
A
-
E
V
-
Y
K
L
G
Y
E
L
V
D
G
T
---------
T
P
E
K
Y
R
S
I
W
W
T
----
T
N
----
K
D
------
N
--
K
E
---
I
I
F
D
V
Q
Y
K
---------------
S
P
D
V
Y
--------
N
N
---
M
M
V
C
N
M
V
T
Y
-----
I
N
D
K
---------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.48
100%
95
- C4 -
2VED
1
?
A:
[16-41]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
R
I
K
D
E
E
D
V
E
------------
K
E
L
G
L
---------
P
V
L
G
S
I
Q
K
F
N
-----------------
2
PsiBlast_PDB
45.38
100%
86
- C4 -
3BFV
1
CAP8A_STAAU
A:
[16-41]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
R
I
K
D
E
E
D
V
E
------------
K
E
L
G
L
---------
P
V
L
G
S
I
Q
K
F
N
-----------------
10
PsiBlast_CBE
44.82
100%
91
- C4 -
3BFV
1
B:
[16-41]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
R
I
K
D
E
E
D
V
E
------------
K
E
L
G
L
---------
P
V
L
G
S
I
Q
K
F
N
-----------------
9
PsiBlast_CBE
44.69
100%
73
- C4 -
2VED
1
?
B:
[16-41]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
R
I
K
D
E
E
D
V
E
------------
K
E
L
G
L
---------
P
V
L
G
S
I
Q
K
F
N
-----------------
12
HHSearch
44.19
8%
-17
- C4 -
3B8M
-
?
A:
[64-205]
-------------------------------------------------------------------------------------------------------------
K
W
T
S
A
A
-----
V
V
T
P
P
E
--------
P
V
Q
W
Q
E
L
E
K
T
F
T
K
L
R
V
L
D
L
D
I
K
I
D
R
T
E
---
A
------
F
N
-
L
F
I
------------
K
K
F
Q
--------
S
--
V
S
-
L
L
-
E
E
Y
L
R
S
S
P
Y
V
M
D
QDELD
L
H
R
A
I
V
A
L
S
E
K
M
K
A
----
V
D
----
D
N
ASKKKD
E
--
P
S
L
Y
T
S
W
-
T
L
S
F
T
---------------
A
P
T
S
E
--------
E
A
---
Q
T
V
L
S
G
Y
I
D
-----
Y
I
S
A
L
V
-------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
42.54
10%
9
- C3 -
2LAK
-
?
A:
[1-160]
-----------------------------------------------
M
E
K
A
M
P
E
S
F
V
V
R
R
E
A
H
L
A
A
-
P
P
A
A
--------
V
F
A
L
M
-
T
D
P
E
K
I
L
----------
R
W
M
--------
G
T
-----
E
A
E
V
E
P
--------
E
P
G
G
L
Y
L
V
N
----
V
T
-----
G
A
R
F
A
------------
R
G
-
S
F
R
------------
E
V
V
P
--------
V
--
H
R
-
L
A
-
Y
S
F
G
W
D
G
S
E
V
V
---------
P
P
G
S
S
L
V
E
I
D
L
----
I
E
----
Q
G
G-----
G
--
T
L
---
L
R
-
L
T
H
S
G
---------------
L
P
S
A
E
--------
Q
C
---
A
G
H
E
E
G
W
A
H
-----
Y
L
G
R
L
T
E
V
-
A
-
A
G
R
D
P
G
P
D
P
F
Y
G
R
R
L
E
H
---
H
--------------------------------------------------------------------------------------------
H
H
H
H
-----------------
8
PsiBlast_PDB
39.64
25%
18
- C4 -
4IJA
3
?
A:
[244-314]
----------------------------------------------------------------------------------------------------------------------------
N
G
--------
E
A
G
E
I
G
K
T
L
----
V
S
-----
K
V
S
D
N
V
E
---
I
------
F
H
-
K
I
E
------------
D
I
F
S
--------
Q
--
E
A
-
L
L
-
H
N
L
S
N
Q
L
N
E
K
M
---------
T
L
S
K
L
I
Q
F
Y
N
E
----
K
N
P
V
V
V
E
E
------
M
--
E
Q
---
F
I
-
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
38.09
15%
65
- C3 -
2JSO
-
PMRD_ECOLI
A:
[1-88]
----------------------------------------------------------------------------------------------------------------------------
M
E
--------
W
L
V
K
K
S
C
C
N
----
K
Q
-----
D
N
R
H
V
L
M
---
L
------
C
D
-
A
G
G
------------
A
I
K
M
--------
I
--
A
E
-
V
K
-
S
D
F
A
V
K
V
G
D
L
L
---------
S
P
--
L
Q
N
A
L
Y
C
----
I
N
----
R
E
------
K
--
L
H
---
T
V
-
K
V
L
S
A
---------------
S
S
Y
S
P
--------
D
E
---
W
E
R
Q
C
K
V
A
G
-----
K
T
Q
----------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
37.88
14%
34
- C3 -
3WOE
-
?
B:
[3-106]
---------------------------------------------------------------------------------------------------------------------------------------
V
E
P
Y
I
R
L
F
----
E
A
-----
I
P
D
A
E
T
E
---
L
------
A
T
-
F
Y
D
------------
A
D
L
D
--------
T
LP
P
R
M
F
L
-
P
S
-----
G
D
L
Y
---------
T
P
P
G
P
V
R
L
E
E
I
----
K
R
----
K
R
------
R
--
V
R
---
L
V
-
K
V
S
I
Y
---------------
R
F
E
H
V
--------
G
L
---
G
L
A
A
R
P
Y
A
Y
-----
A
Y
A
W
Q
G
D
N
G
I
-
L
H
L
Y
H
A
P
V
V
L
E
D
--------------------------------------------------------------------------------------------------------------------------
18
HHSearch
34.94
2%
14
- C4 -
1WJW
-
A:
[59-99]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
V
----
R
P
----
S
G
------
T
--
E
D
---
I
V
-
R
V
Y
A
E
---------------
A
N
S
Q
E
--------
S
A
---
D
R
L
A
Y
E
V
S
L
-----
L
V
F
Q
L
A
G
G
-----------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
34.93
10%
29
- C4 -
2QN6
-
B:
[43-84]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
K
I
----
Y
T
-----
I
------
G
--
A
P
---
R
Y
-
R
V
D
V
V
---------------
G
T
N
P
K
--------
E
A
---
S
E
A
L
N
Q
I
I
S
-----
N
L
I
K
I
G
K
E
-
E
---------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
34.46
31%
99
- C4 -
1KFA
-
?
L:
[170-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
D
S
K
D
---------
S
T
Y
S
M
S
S
T
L
T
L
----
T
K
----
D
E
------
Y
--
E
R
---
H
A
-
S
Y
T
C
E
---------------
A
A
H
K
T
--------
S
T
---
S
P
I
A
K
S
F
N
R
-----
A
------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
34.33
15%
60
- C4 -
1YZ7
-
IF2A_PYRAB
A:
[220-265]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
A
P
---
R
Y
-
R
I
D
I
T
---------------
A
P
D
Y
Y
--------
K
A
---
E
E
V
L
E
S
I
A
E
-----
E
I
L
R
V
I
K
E
-
A
---
G
G
E
A
T
L
L
R
K
E
K
-------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.23
27%
-43
- C4 -
2K1K
-
EPHA1_HUMAN
A:
[548-569]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
V
I
F
G
L
L
L
G
-------
A
A
L
L
-----
L
G
I
-
L
V
F
R
---------------------------------------------------------------------