@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1940: (2016-03-30 )
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
Atome Classification :
(48 SA)
.........10........20........30......-..40........50........60........70........80........90........100.......110.......120...--..-..130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTKGTPHIQPN
G
V
K
I
A
K
T
VLMPGDP
L
R
A
K
Y
I
A
D
N
F
L
E
-
N
V
E
Q
F
N
D
V
R
N
M
FGYTGTYKG
K
E
V
S
V
MGSGMGI
P
S
I
G
I
Y
S
Y
E
L
Y
N
F
F
D
V
D
T
I
I
R
IGSCG
A
L
Q
ENV
N
L
Y
D
V
I
I
A
QAASTNSNY
V
D
QYNIP--GH-FAPIA
D
F
E
L
V
T
K
A
K
N
V
A
D
Q
IGATTHVGNVLSSDTFYNADPT
F
N
D
A
W
K
KMG
I
L
G
I
E
MESA
G
L
Y
L
N
A
IHAG
K
K
A
L
G
I
F
TVS
D
H
I
LRDEATT
P
E
E
R
Q
N
S
F
T
Q
M
M
E
I
A
L
EIAE
3
PsiBlast_PDB
92.89
53%
-107
- C3 -
1VHJ
-
DEOD1_VIBCH
A:
[2-231]
---
A
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
---
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
94
PsiBlast_CBE
92.85
52%
-105
- C3 -
1K9S
4
DEOD_ECOLI
F:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
23
PsiBlast_CBE
92.40
53%
-102
- C3 -
1VHW
2
DEOD1_VIBCH
D:
[4-233]
---
A
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
87
PsiBlast_CBE
92.39
52%
-108
- C3 -
3ONV
2
DEOD_ECOLI
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
79
PsiBlast_CBE
92.33
52%
-108
- C3 -
3OOH
2
DEOD_ECOLI
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
24
PsiBlast_CBE
92.28
53%
-104
- C3 -
1VHW
2
DEOD1_VIBCH
C:
[4-233]
---
A
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
58
PsiBlast_CBE
92.04
52%
-101
- C3 -
4RJ2
1
?
E:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
60
PsiBlast_CBE
91.88
52%
-101
- C3 -
4RJ2
1
?
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
25
PsiBlast_CBE
91.87
53%
-100
- C3 -
1VHW
2
DEOD1_VIBCH
B:
[4-233]
---
A
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
78
PsiBlast_CBE
91.85
52%
-103
- C3 -
3OOH
2
DEOD_ECOLI
D:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
96
PsiBlast_CBE
91.84
52%
-104
- C3 -
1K9S
4
DEOD_ECOLI
D:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
8
PsiBlast_PDB
91.76
52%
-103
- C3 -
1K9S
4
DEOD_ECOLI
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
4
PsiBlast_PDB
91.68
53%
-101
- C3 -
1VHW
2
DEOD1_VIBCH
A:
[4-233]
---
A
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
54
PsiBlast_CBE
91.67
52%
-105
- C3 -
4TS3
3
?
D:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
28
PsiBlast_CBE
91.67
53%
-102
- C3 -
3OF3
2
DEOD1_VIBCH
J:
[3-231]
----
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
104
PsiBlast_CBE
91.65
52%
-112
- C3 -
1A69
4
DEOD_ECOLI
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
----
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
33
PsiBlast_CBE
91.59
53%
-101
- C3 -
3OF3
4
DEOD1_VIBCH
E:
[3-231]
----
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
67
PsiBlast_CBE
91.54
52%
-103
- C3 -
3OOH
11
DEOD_ECOLI
O:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
31
PsiBlast_CBE
91.43
53%
-101
- C3 -
3OF3
2
DEOD1_VIBCH
G:
[3-231]
----
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
22
PsiBlast_CBE
91.40
53%
-101
- C3 -
1VHW
2
DEOD1_VIBCH
E:
[5-233]
----
T
P
H
I
N
A
Q
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
N
F
L
D
-
N
A
V
Q
V
C
D
V
R
N
M
F
G
Y
T
G
T
Y
K
G
R
R
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
V
T
E
L
I
K
D
Y
G
V
K
K
I
I
R
V
G
S
C
G
A
V
N
E
G
I
K
V
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
Y
K
M
V
K
A
A
E
E
A
A
K
A
R
G
I
D
V
K
V
G
N
L
F
S
A
E
L
F
Y
T
P
D
P
S
M
F
D
V
M
D
K
Y
G
I
V
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
Y
G
A
K
A
L
A
I
C
T
V
S
D
H
I
K
T
G
E
Q
T
T
S
E
E
R
Q
N
T
F
N
E
M
I
E
I
A
L
D
---
19
PsiBlast_PDB
91.31
52%
-110
- C3 -
1A69
4
DEOD_ECOLI
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
63
PsiBlast_CBE
91.05
52%
-104
- C3 -
3UT6
3
DEOD_ECOLI
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
106
PsiBlast_CBE
91.03
52%
-106
- C3 -
1PW7
2
DEOD_ECO57
C:
[3-231]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
101
PsiBlast_CBE
91.01
52%
-102
- C3 -
1OU4
2
DEOD_ECOLI
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
10
PsiBlast_PDB
91.01
52%
-103
- C3 -
1PK9
2
DEOD_ECO57
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
103
PsiBlast_CBE
91.00
52%
-104
- C3 -
1OTY
2
DEOD_ECOLI
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
102
PsiBlast_CBE
90.88
52%
-103
- C3 -
1OTY
2
DEOD_ECOLI
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
20
PsiBlast_PDB
90.86
52%
-101
- C3 -
1OTY
2
DEOD_ECOLI
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
108
PsiBlast_CBE
90.67
52%
-102
- C3 -
1PW7
2
DEOD_ECO57
A:
[3-231]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
107
PsiBlast_CBE
90.66
52%
-104
- C3 -
1PW7
2
DEOD_ECO57
B:
[3-231]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
62
PsiBlast_CBE
90.62
52%
-103
- C3 -
3UT6
5
DEOD_ECOLI
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
110
PsiBlast_CBE
90.57
52%
-107
- C3 -
1PR6
2
DEOD_ECO57
B:
[3-231]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
----
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
11
PsiBlast_PDB
90.45
52%
-103
- C3 -
1PKE
2
DEOD_ECO57
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
105
PsiBlast_CBE
90.36
52%
-105
- C3 -
1A69
2
DEOD_ECOLI
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
99
PsiBlast_CBE
90.22
52%
-106
- C3 -
1OU4
2
DEOD_ECOLI
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
89
PsiBlast_CBE
90.22
52%
-103
- C3 -
1PKE
2
DEOD_ECO57
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
9
PsiBlast_PDB
90.21
52%
-104
- C3 -
1PK7
2
DEOD_ECO57
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
92
PsiBlast_CBE
89.92
52%
-108
- C3 -
1PK7
2
DEOD_ECO57
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
91
PsiBlast_CBE
89.91
52%
-104
- C3 -
1PK9
2
DEOD_ECO57
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
90
PsiBlast_CBE
89.57
52%
-105
- C3 -
1PK9
2
DEOD_ECO57
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
15
PsiBlast_PDB
89.46
52%
-104
- C3 -
3UT6
4
DEOD_ECOLI
A:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
93
PsiBlast_CBE
89.33
52%
-103
- C3 -
1PK7
2
DEOD_ECO57
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
109
PsiBlast_CBE
89.22
52%
-107
- C3 -
1PR6
2
DEOD_ECO57
C:
[3-231]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
-----
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
100
PsiBlast_CBE
89.12
52%
-105
- C3 -
1OU4
2
DEOD_ECOLI
B:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
T
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
88
PsiBlast_CBE
87.76
52%
-108
- C3 -
1PKE
2
DEOD_ECO57
C:
[2-230]
----
T
P
H
I
N
A
E
M
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
T
F
L
E
-
D
A
R
E
V
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H
G
M
G
I
P
S
C
S
I
Y
T
K
E
L
I
T
D
F
G
V
K
K
I
I
R
V
G
S
C
G
A
V
L
P
H
V
K
L
R
D
V
V
I
G
M
G
A
C
T
D
S
K
-
V
N
R
I
R
F
K
--
D
H
D
F
A
A
I
A
D
F
D
M
V
R
N
A
V
D
A
A
K
A
L
G
I
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
P
D
G
E
M
F
D
V
M
E
K
Y
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
R
T
H
E
Q
T
-----
Q
T
T
F
N
D
M
I
K
I
A
L
E
---
111
HHSearch
85.87
47%
-106
- C3 -
1Z34
1
?
A:
[1-233]
---
A
T
P
H
N
S
A
Q
V
G
D
F
A
E
T
V
L
M
C
G
D
P
L
R
A
K
L
I
A
E
T
Y
L
E
-
N
P
K
L
V
N
N
V
R
G
I
Q
G
Y
T
G
T
Y
K
G
K
P
I
S
V
M
G
H
G
M
G
L
P
S
I
C
I
Y
A
E
E
L
Y
S
T
Y
K
V
K
T
I
I
R
V
G
T
C
G
A
I
D
M
D
I
H
T
R
D
I
V
I
F
T
S
A
G
T
N
S
K
I
N
R
I
R
F
M
D
--
H
D
-
Y
P
A
T
A
S
F
D
V
V
C
A
L
V
D
A
A
K
E
L
N
I
P
A
K
V
G
K
G
F
S
T
D
L
F
Y
N
P
Q
T
E
L
A
Q
L
M
N
K
F
H
F
L
A
V
E
M
E
S
A
G
L
F
P
I
A
D
L
Y
G
A
R
A
G
C
I
C
T
V
S
D
H
I
L
H
H
E
E
-----
R
Q
N
S
F
Q
N
M
M
K
I
A
L
E
A
A
I
113
HHSearch
84.81
47%
-99
- C3 -
3UAW
5
DEOD_BACCE
A:
[2-233]
----
S
V
H
I
E
A
K
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
-
T
F
L
E
D
V
T
C
Y
N
N
V
R
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
G
T
G
M
G
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
Y
G
V
K
N
L
I
R
V
G
T
C
G
A
I
Q
K
D
V
K
V
R
D
V
I
I
A
M
T
A
C
T
D
S
N
M
N
R
L
T
F
P
G
--
F
D
-
F
A
P
A
A
N
F
D
L
L
K
K
A
Y
D
A
G
T
E
K
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
E
S
M
D
M
V
K
K
L
G
D
Y
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
D
H
I
F
T
G
E
E
T
T
S
E
E
R
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
I
119
HHSearch
74.27
33%
-106
- C3 -
1JE0
2
PNPH_SULSO
A:
[3-235]
----
P
V
H
I
L
A
K
K
G
E
V
A
E
R
V
L
V
V
G
D
P
G
R
A
R
L
L
S
T
-
L
L
Q
-
N
P
K
L
T
N
E
N
R
G
F
L
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
T
H
G
I
G
G
P
S
I
A
I
V
L
E
E
L
A
-
M
L
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
V
P
Y
I
N
L
G
E
Y
I
I
V
T
G
A
S
Y
N
Q
G
G
L
F
Y
Q
Y
L
R
DN
A
C
-
V
A
S
T
P
D
F
E
L
T
N
K
L
V
T
S
F
S
K
R
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
E
D
E
E
F
V
K
K
W
S
S
R
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
A
-------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T