@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0834: (2015-12-18 )
MCGVLSLQARLSFENCSKPLDCSLFATTCTPQNPIGSCMVSSQGGVCGVLSLQARLSFENCSKPLDCSLFATTCTPQNPIGSCMVSSQGGVRGVLSLQARLSFKNCFLVKSLKPSQLTLMLTGFLGGFSFLTTGFW
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-....10.....----------...20----...-....--.30-.--....-...---40........50..-.----------.....------------60.....--.-----------..70........80-----......----...90.--.......100...-.-------.-.-.110..--.....120---..---.....--..130....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCG
V
L
-
S
L
Q
A
R
LSFENC----------SKPLD----
C
S
L
-
F
A
T
T--CTP-Q--NPIG-
S
C
M
---VSSQGG
V
C
G
V
L
S
L
Q
-
A
----------RLSFE------------NCSKPLD--
C
-----------
S
L
F
A
T
TCTPQNPI------G
S
C
M
VS----SQGG
V
R
--
G
V
L
S
L
Q
A
R
LSFK
N
-
C
-------
F
-
L
-
V
KSLKP--S
Q
L
T
L
M
-----
L
T
---
G
F
LG
G
--
F
S
F
L
TTGFW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
84.72
22%
-112
* C8 *
1UT1
9
DRAA_ECOLX
A:
[9-148]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G
S
F
T
P
S
G
T
T
G
T
T
-
K
L
T
V
T
E
K
C
Q
V
R
----------
V
G
D
L
T
----
V
A
K
-
T
R
G
Q
--
L
T
D
-
A
--
A
P
I
G
-
P
V
T
---
V
Q
A
L
G
C
D
A
R
Q
V
A
L
K
-
A
DTDNFEQG
K
F
F
L
I
S
D
------------
N
N
R
D
K
L
Y
--
V
-----------
N
I
R
P
T
D
N
S
A
W
T
T
D
N-----
G
V
F
Y
K
N
----
D
V
G
S
W
G
--
G
I
I
G
I
Y
V
D
G
Q
Q
T
N
----------------
T
P
P
--
G
N
Y
T
L
T
-----
L
T
---
G
------------
G
Y
W
A
K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
74.08
19%
-111
- C8 -
3EBK
-
BLG4_BLAGE
A:
[7-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NE
D
C
F
R
H
E
S
L
V
P
N
L
D
Y
E
R
F
R
G
S
W
I
I
AAGT
S
E
A
L
T
----
Q
Y
K
C
W
I
D
R
--
F
S
Y
-
D
--
D
A
L
V
-
S
K
Y
---
T
D
S
Q
G
K
--
N
R
T
T
I
R
-
G
----------
R
T
K
F
E
------------
G
N
K
F
T
I
D
--
Y
NDKGKAF
S
A
P
Y
S
V
L
A
T
D
Y
E
N
Y
A
I
V
------
E
G
C
P
A
A
----
A
N
G
H
-----
V
I
Y
V
Q
L
R
M
T
L
R
R
-
F
HPKM
L
Q
H
Y
-
T
-
L
D
Q
V
N
Q
N
K
K
A
I
E
E
D
-----
L
K
---
H
F
N
L
K
--
Y
E
D
L
H
S
T
C
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
71.56
23%
-144
* C10 *
4CI2
2
CRBN_CHICK
B:
[71-451]
MINFDTSLPTSHMYLGSDMEEFH
G
R
T
L
H
D
D
D
S
C
Q
V
I
P
V
L
PHVM
V
M
L
I
PG
Q
T
L
P
L
Q
L
F
H
P
Q
E
V
S
M
V
R
N
L
I
Q
KDR
T
F
A
V
L
AYSNVREREAH
F
G
T
T
A
E
I
Y
A
Y
R
E
E
Q
E
YG
I
E
T
V
K
V
K
A
I
G
R
Q
R
F
K
V
L
E
I
R
T
Q
SDG
I
Q
Q
A
K
V
Q
I
L
P
E
R
V
L
P
S
TMSAVQLQSLSRRHIRAF
R
Q
W
W
Q
K
Y
Q
K
R
K
F
H
CASLTSWP
P
W
L
Y
S
L
Y
D
A
E
T
L
M
E
R
V
K
R
Q
L
H
E
W
D
E
NLKDESLPTN
P
I
D
F
S
Y
R
V
A
A
C
LPID
D
A
L
R
I
Q
L
L
K
I
G
-
S
A
I
Q
R
L
R
C
E
L
D
----------
I
M
N
K
C
----
T
S
L
-
C
C
K
Q
--
C
---------
Q
-
D
T
E
---
I
T
T
K
N
E
I
F
S
-
L
S
L
---------------------------------------------------------
C
G
P
----------
M
A
A
Y
V
N
----
P
H
G
Y
I
H
--
E
T
L
T
V
-----
Y
K
A
-
C
-------
N
-
L
-
N
L
S
G
R
P
--
S
T
E
H
------------
S
W
F
P
G
--
Y
A
W
T
I
A
Q
C
R
ICGNHM
G
W
K
F
T
A
TKKDMSPQKFWGLTRSALLPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
68.44
24%
-79
- C1 -
4EEI
12
?
A:
[1-433]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIKRYDV
A
E
I
S
K
I
W
A
D
E
N
K
Y
A
K
M
L
E
V
E
L
A
I
L
E
A
L
E
DRMVPKG
T
A
A
E
I
R
A
R
A
Q
-
I
R
P
E
R
V
D
E
I
E
K
----------
V
T
K
H
D
----
I
I
A
-
F
C
T
S
--
I
A
E
-
Q
F
T
A
E
T
G
-
K
F
F
HFG
V
T
S
S
D
I
I
D
S
A
L
S
L
Q
-
I
----------
R
D
S
M
S
------------
Y
V
I
K
D
L
E
A
L
C
-----------
D
S
L
L
T
K
A
E
E
T
K
E
I
------
I
T
M
G
R
S
HG
M
F
A
E
P
M
S
F
--
G
Q
K
F
L
G
A
Y
V
E
F
K
R
-
R
-------
L
-
K
D
L
K
D
F
Q
K
--
D
G
L
T
V
Q
-----
F
S
---
G
A
V
G
N
--
Y
C
I
L
T
T
E
D
E
K
K
A
A
D
I
L
GLPVEEVSTQVIPR
D
R
I
A
K
L
I
S
I
H
G
L
I
A
S
A
I
E
R
L
A
V
E
I
R
H
L
H
RSDVFE
V
Y
E
G
FKKNP
I
S
T
E
N
L
T
G
M
A
R
M
L
R
S
H
V
S
I
A
L
E
N
C
VLWHERDI
S
H
S
S
A
E
R
F
Y
L
P
D
N
F
G
I
M
V
Y
A
L
R
R
M
K
N
T
I
D
N
LVVQ
R
D
I
I
E
D
R
V
R
S
T
SAY
L
S
S
F
Y
L
H
F
L
V
A
NTPFM
R
E
D
C
Y
K
I
V
Q
Q
VES
F
S
K
K
L
Q
K
V
M
H
D
EHN
I
I
L
D
I
P
EMD
F
E
G
I
K
K
T
YLKE
I
D
H
V
F
D
R
S
V
KAR
25
Fugue
66.83
19%
-97
- C8 -
2QUO
1
A:
[4-126]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
I
L
-
D
L
A
A
A
T
E
R
L
N
L
----------
T
D
A
L
N
------------------
S
--
N
P
A
G
N
L
Y
D
---
W
R
S
S
N
S
Y
P
W
T
Q
K
L
N
-
L
----------
H
L
T
I
T
--------------
A
T
G
Q
K
--
Y
-----------
R
I
L
A
S
-----
K
I
V
------
D
F
N
I
Y
S
----
N
N
F
N
N
L
--
V
K
L
E
Q
S
L
G
D
G
V
K
D
-
H
-------
Y
-
V
-
D
I
S
L
D
A
--
G
Q
Y
V
L
V
-----
M
K
A
N
S
S
Y
S
G
N
Y
P
Y
S
I
L
F
Q
K
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
62.57
8%
-126
- C10 -
2UV4
1
A:
[8-150]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HEFPK
P
E
F
M
S
K
S
L
E
E
L
-
Q
I
G
T
Y
A
N
I
A
M
V
----------
R
T
T
T
P
----
V
Y
V
-
A
L
G
I
--
F
V
Q
-
H
--
R
V
S
A
-
L
P
V
---
V
D
E
K
G
R
V
V
D
I
Y
S
K
F
-
D
----------
V
I
N
L
A
------------
A
E
K
T
Y
N
N
----------------------
L
D
V
S
V
------
T
K
A
L
Q
H
----
R
S
H
Y
F
E
--
G
V
L
K
C
Y
L
H
E
T
L
E
T
-
I
-------
I
N
R
-
L
V
E
A
E
V
--
H
R
L
V
V
V
D
ENDV
V
K
---
G
I
V
S
L
--
S
D
I
L
Q
A
L
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
62.33
17%
-100
- C7 -
3SDE
6
PSPC1_HUMAN
A:
[7-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIKSFLKP
G
E
K
T
Y
-
T
Q
R
C
R
L
F
V
G
N
L
----------
P
T
D
I
T
----
E
E
D
-
F
K
R
L
--
F
E
R
-
Y
--
G
E
P
S
-
E
V
F
---
I
N
R
D
R
G
-
F
G
F
I
R
L
E
-
S
----------
R
T
L
A
E
------------
I
A
K
A
E
L
D
---------------------------------------------
G
T
I
L
--
K
S
R
P
L
R
I
R
F
A
T
H
G
A
A
-------
L
-
T
-
V
K
N
L
S
P
--
V
V
S
N
E
L
-----
L
E
---
Q
A
F
S
Q
--
F
G
P
V
E
K
A
V
V
V
V
D
DRGRATG
K
G
F
V
E
F
AAK
P
P
A
R
K
A
L
E
R
C
G
D
G
AFLLTTTP
R
P
V
I
V
E
P
M
E
Q
F
D
DEDGLPEKLMQKT
Q
Q
Y
H
K
E
R
EQPPRFAQPGT
F
E
F
E
Y
A
S
R
W
K
A
L
D
E
M
E
K
Q
Q
R
E
Q
V
D
R
N
I
R
E
A
K
E
K
L
E
A
E
M
E
A
A
R
H
E
H
Q
L
M
LM--------------------------------------------------------------------------------------
29
Fugue
62.21
16%
-88
- C7 -
4UJ5
1
?
C:
[23-194]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q
P
I
V
K
D
C
K
E
A
-
D
L
S
L
Y
N
E
F
R
L
W
----------
K
D
E
P
T
MDRT
C
P
F
-
L
D
K
I
--
Y
Q
E
D
I
--
F
P
C
L
-
T
F
S
---
K
S
E
L
A
S
A
V
L
E
A
V
E
N
-
N
----------
T
L
S
I
E
P
V
G
L
QP
I
R
F
V
KA
E
C
G
G
P
K
K
--
C
-----------
A
L
T
G
Q
S
K
S
C
K
H
R
I
K
L
GDS
S
N
Y
Y
Y
I
S
----
P
F
C
R
Y
R
I
T
S
V
C
N
F
F
T
Y
I
R
Y
I
Q
-
Q
-------
G
-
L
-
V
K
Q
Q
D
V
--
D
Q
M
F
W
E
-----
V
M
---
Q
L
R
K
E
--
M
S
L
A
K
L
G
Y
F
K
E
E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
61.72
20%
-58
- C7 -
4Q6O
8
?
A:
[21-437]
---------------------------------------------------------------------------------------------------------MIEKAPTNVEDRDK
A
P
H
L
L
L
L
A
GIQGDE
P
G
G
F
N
A
T
N
L
F
L
M
HYSVL
K
G
L
V
E
V
VPVLN
K
P
S
M
L
R
NHRGLYGDMNRKFAALDKNDPE
Y
P
T
I
Q
E
I
K
S
L
I
A
KPSID
A
V
L
H
L
H
D
G
G
G
YYRPVYVDAMLNPKRWGN
C
F
I
I
DQDE
V
K
G
A
K
-
F
P
N
L
L
A
F
A
N
N
T
----------
I
E
S
I
N
----
A
H
L
-
L
------------
H
P
I
E
-
E
Y
H
---
L
K
N
T
R
T
A
Q
G
D
T
E
M
Q
-
K
----------
A
L
T
F
Y
------------
A
I
N
Q
K
K
---------------
S
A
F
A
N
E
A
S
K
E
L
P
L
------
A
S
R
V
F
Y
----
H
L
Q
A
I
E
--
G
L
L
N
-
Q
L
N
I
P
F
K
R
-
D
-------
F
-----
D
L
N
P
--
N
S
V
H
A
L
-----
I
N
--------------
D
K
N
L
W
A
K
I
SSLPKMPLFNLRPKLNH
F
P
L
P
H
NTKIPQI
P
I
E
S
NAYI
V
G
L
V
K
N
KQ
E
V
F
L
K
YGNKLMTRLS
P
F
Y
I
E
FDPSLE
E
V
K
M
Q
I
DN
K
D
Q
M
V
K
IG
S
V
V
E
V
K
E
S
F
Y
I
H
A
MDN
I
R
A
N
VIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQER
I
Y
R
I
E
F
Y
KNNAFS
G
M
I
L
V
K
F
V-----------------------------------------------------
3
PsiBlast_PDB
55.18
61%
-134
- C11 -
3VYS
1
?
B:
[335-360]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
----
C
P
L
-
F
G
K
T
--
C
T
P
-
R
--
H
P
V
G
-
P
C
M
---
V
S
Y
E
G
T
C
Q
I
F
Y
K
Y
G
-
V
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
54.40
61%
-117
- C11 -
3VYU
1
?
B:
[335-360]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
----
C
P
L
-
F
G
K
T
--
C
T
P
-
R
--
H
P
V
G
-
P
C
M
---
V
S
Y
E
G
T
C
Q
I
F
Y
K
Y
G
-
V
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
54.23
61%
-116
- C11 -
3VYR
3
?
B:
[335-360]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
----
C
P
L
-
F
G
K
T
--
C
T
P
-
R
--
H
P
V
G
-
P
C
M
---
V
S
Y
E
G
T
C
Q
I
F
Y
K
Y
G
-
V
----------
L
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.20
61%
-129
- C11 -
3VYT
1
?
B:
[335-360]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
D
----
C
P
L
-
F
G
K
T
--
C
T
P
-
R
--
H
P
V
G
-
P
C
M
---
V
S
Y
E
G
T
C
Q
I
F
Y
K
Y
G
-
V
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
49.84
28%
-82
- C6 -
1G6A
1
BLP4_PSEAI
A:
[97-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
--
D
-----------
A
C
F
A
T
M
T
T
S
D
N
T
A
------
A
N
I
I
L
S
----
A
V
G
G
P
K
--
G
V
T
D
F
L
R
Q
I
G
D
K
E
-
T
-------
R
-
L
-
D
R
-
I
E
P
--
D
----
L
-----
N
E
---
G
K
L
G
D
--
L
R
D
T
T
T
P
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.96
28%
-78
* C6 *
1G68
1
BLP4_PSEAI
A:
[97-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
--
D
-----------
A
C
F
A
T
M
T
T
S
D
N
T
A
------
A
N
I
I
L
S
----
A
V
G
G
P
K
--
G
V
T
D
F
L
R
Q
I
G
D
K
E
-
T
-------
R
-
L
-
D
R
-
I
E
P
--
D
----
L
-----
N
E
---
G
K
L
G
D
--
L
R
D
T
T
T
P
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
41.73
15%
-32
* C7 *
1QYS
-
?
A:
[3-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Q
V
Q
V
N
I
D
D
N
----------
G
K
N
F
D
----
Y
T
Y
-
T
V
T
T
-----------------------
E
S
E
L
Q
K
V
L
N
E
L
M
D
----------
Y
I
K
K
Q
------------
G
A
-
K
R
V
R
--
I
-----------
S
I
T
A
R
T
------------------------
K
K
E
A
E
--
K
F
A
A
I
L
I
K
V
F
A
E
L
-
G
-------
Y
-
N
-
D
I
N
V
T
F
--
D
G
D
T
V
T
-----
V
E
---
G
Q
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
33.23
26%
-64
- C2 -
1ZLH
-
TCI1_RHIBU
B:
[2-51]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
----
C
V
S
-
K
G
F
G
--
C
L
P
-
Q
--
S
D
C
P
-
Q
E
A
---
R
L
S
Y
G
G
C
S
T
V
C
-------------------
C
------------
D
L
S
K
L
T
G
--
C
-----------
K
G
K
G
G
E
C
N
P
L
D
R
Q
------
C
K
E
L
Q
A
----
E
S
A
S
C
G
--
K
G
Q
K
C
C
V
W
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
32.78
34%
-99
- C6 -
2HRB
3
CBR3_HUMAN
A:
[108-161]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
----
T
N
F
-
F
A
T
R
N
M
C
N
E
-
L
--
L
P
I
--------
M
K
P
H
G
R
V
V
N
I
S
S
L
Q
-
C
----------
L
R
A
F
E
------------
N
C
S
E
D
L
Q
--
E
-----------
R
F
H
S
E
T
L
T
E
G
D
L
V
------
D
L
M
K
K
F
----
V
E
D
T
K
N
--
E
V
H
E
R
E
G
W
P
N
S
P
Y
-
G
-------
V
-
S
-
K
L
G
V
T
V
--
L
S
R
I
L
A
-----
R
R
---
L
D
E
K
R
--
K
A
D
R
I
L
V
N
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
29.98
37%
-55
- C5 -
3D2N
2
MBNL1_HUMAN
A:
[20-59]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
S
R
-
P
D
T
E
--
C
K
F
-
A
--
H
P
S
K
-
S
C
Q
---
V
E
N
G
R
V
I
A
C
F
D
S
L
K
-
G
----------
R
C
S
R
E
------------
N
C
K
Y
L
H
P
--
P
-----------
P
H
L
K
T
Q
L
E
I
N
G
R
N
------
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
29.91
41%
9
* C11 *
2Z1D
1
?
A:
[331-367]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
------------
G
L
A
L
P
T
D
--
C
-----------
P
L
F
G
K
T
C
T
P
R
H
P
V
------
G
P
C
M
V
S
----
Y
E
G
T
C
Q
--
I
F
Y
K
Y
G
V
L
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------