@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1444: (2016-03-24 )
LTKLKKVMISVIAATLLLLAGCGSSAVIKTDAGSVTQDELYEAMKTTYGNEVVQQLTFKKILEDKYTVTEKEVNAEYKKYEEQYGDSFESTLSSNNLTKTSFKENLEYNLLVQKATEANMDVSESKLKAYYKTWEPDITVRHILVDDEATAKEIQTKLKNGEKFTDLAKEYSTDTATSTNGGLLDPFGPGEMDETFEKAAYALENKDDVSGIVKSTYGYHLIQLVKKTEKGTYAKEKANVKAAYIKSQLTSENMTAALKKELKAANIDIKDSDLKDAFADYTSTSSTSSTTTSN
Atome Classification :
(20 SA)
.........10.....--...20........30........40......----------------..50........60.....-----...70........80....---.----...90...-.....100.......110.....-----.---.120---........130----....------------.------...140...------------..------------------------------------------------------------------------------------------------------------------------.---------------------.----------------------150..--......-.-160----.-..-......170.......180.......-190---.......200.......210.---------....-...220.......--230.-........240.......250.......260.......270.......280.......290..------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
L
T
K
L
K
K
V
M
I
S
V
I
A
A
T
L
--
L
L
L
AGCGS
S
A
V
I
KTDAGSV
T
Q
D
E
L
Y
E
A
M
K
T
T----------------Y
G
N
E
V
V
Q
Q
L
T
F
K
K
I
LEDKY-----TV
T
E
K
E
V
N
A
E
Y
K
K
Y
E
E
Q
YG---
D
----
S
F
E
S
T
LSS-NNLT
K
T
S
F
KENL
E
Y
N
L
L
V
Q
KATE-----A---NMD----
V
S
E
S
K
L
K
A
Y
Y
-----
K
TWE------------P------D
I
T
V
R
H
I
L
V------------DD------------------------------------------------------------------------------------------------------------------------E---------------------
A
----------------------
T
--
A
K
--
E
I
Q
T
K
L-K-N------G-
E
K
-
F
T
D
L
A
K
E
YSTDTATSTNGGLLDPFGP-
G
E
M
---
D
E
T
F
E
K
A
A
Y
ALENK
D
D
V
S
-
G
I
---------
V
K
ST-
Y
G
Y
H
L
I
Q
L
V
K
K
TE--K--G-TYAKEKAN
V
K
A
A
Y
I
K
S
Q
LTS
E
N
M
T
A
A
L
K
K
E
L
KAANIDIKD
S
D
L
K
D
A
F
A
DYTSTSSTSSTTTSN------------------------------------------------------------------------------
70
HHSearch
93.61
24%
-65
- C8 -
3RFW
-
CBF2_CAMJE
A:
[22-273]
--------------------------
A
T
V
A
T
V
N
G
K
S
I
S
D
T
E
V
S
E
F
F
A
P
M
LRGQDFKTLP
D
N
----
Q
K
K
A
L
I
Q
Q
Y
I
M
Q
D
L
I
L
Q
D
A
K
K
Q
NL
E
K
D
P
-
L
Y
T
K
E
L
D
------------------------------
R
A
K
D
A
I
L
V
N
V
Y
Q
E
K
I
L
------
N
---
T
I
K
----
I
D
A
A
K
V
K
A
F
Y
-----
D
Q
N
K
------------
D
KYVK
P
A
R
V
Q
A
K
H
I
L
V
------------
A
T
------------------------------------------------------------------------------------------------------------------------
E
---------------------
K
----------------------
E
--
A
K
--
D
I
I
N
E
L
-
K
-
G
LKG
K
E
L
D
-
A
K
-
F
S
E
L
A
K
E
K
S
I
D
P
G
S
K
N
Q
G
G
E
L
G
W
F
D
Q
-
S
T
M
---
V
K
P
F
T
D
A
A
F
A
L
K
-
N
G
T
I
T
T
T
P
---------
V
K
T
N
-
F
G
Y
H
V
I
L
K
E
N
S
Q
A
K
G
Q
--
I
-
K
F
D
E
V
K
Q
G
I
E
N
G
L
K
F
E
E
F
K
-
K
V
I
N
Q
K
G
Q
D
L
L
N
S
A
K
V
E
Y
K
------------------------------------------------------------------------------------------------------
71
HHSearch
91.65
18%
-43
- C8 -
1M5Y
-
SURA_ECOLI
A:
[27-427]
--------------------------
K
V
A
A
V
V
N
N
G
V
V
L
E
S
D
V
D
G
L
M
Q
S
V
K
L
N
A
A
Q
A
R
Q
Q
L
P
D
D
A
T
L
R
H
Q
I
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
Q
N
N
---
M
T
L
D
-
Q
M
R
S
R
L
A
Y
-
D
G
L
N
Y
N
T
Y
R
N
Q
I
R
K
E
M
I
I
S
E
V
R
N
N
E
V
R
-
R
---
R
I
T
----
I
L
P
Q
E
V
E
S
L
A
-----
Q
Q
V
--------------T-----
E
L
N
L
S
H
I
L
I
------------
P
L
PENPT
S
D
Q
V
N
E
A
E
S
Q
A
R
A
I
V
D
Q
A
R
N
GAD
F
G
K
L
A
I
A
HSADQQALNGGQMGWGRIQELPGIF
A
Q
A
L
S
T
AKKGDIV
G
P
I
R
S
GV
G
F
H
I
L
K
VN
D
L
R
G
E
SKNIS
V
T
E
V
H
A
R
H
I
L
L
K
P
SPIMT
D
E
Q
A
R
---------------------
V
----------------------
K
--
L
E
--
Q
I
A
A
D
I
-
K
-
S
------
G
K
T
T
-
F
A
A
A
A
K
E
F
S
Q
D
P
G
S
A
N
Q
G
G
D
L
G
W
A
T
P
-
D
I
F
---
D
P
A
F
R
D
A
L
T
R
L
N
-
K
G
Q
M
S
-
A
P
---------
V
H
S
S
-
F
G
W
H
L
I
E
L
L
D
T
R
N
--
V
D----------
R
A
Y
R
M
L
M
N
R
K
F
S
-
E
E
A
A
S
W
M
Q
E
Q
R
A
S
A
Y
V
K
I
L
S
-----------------------------------------------------------------------------------------------------
68
HHSearch
83.05
16%
-38
* C9 *
3NRK
-
?
A:
[52-351]
--------------------------
R
V
I
A
T
V
G
T
V
S
I
S
E
L
D
L
D
D
A
T
E
K
Y
N
R
L
Q
KHLKHEDYRKS-
F
R
T
R
I
I
D
F
L
I
D
R
A
I
V
D
V
V
A
E
E
E
SI
Q
V
N
E
Q
R
V
D
S
E
I
E
K
R
M
E
V
M
G
---
I
TN
R
K
Q
F
E
K
T
M
E
T
S
S
G
M
P
F
E
L
W
V
T
E
L
P
Y
Q
I
K
K
G
Q
L
L
Q
-----
L
K
I
A
V
P
P
----
P
N
E
Q
E
I
R
S
W
Y
-----
N
Q
N
K
DKV
G
--------
F
------
E
I
R
Y
R
I
I
S
I
------------
A
P
------------------------------------------------------------------------------------------------------------------------
E
---------------------
N
DS
I
Q
E
E
N
R
L
Y
K
-----------
E
--
V
S
--
E
I
R
K
S
I
-
L
A
D
------
P
-
S
S
-
F
A
L
I
A
G
S
P
R
N
D
P
A
L
R
A
R
R
G
M
V
E
W
I
S
S
-
F
D
L
Y
K
Y
S
K
I
T
A
T
I
A
A
P
L
P
-
N
G
G
V
S
-
E
V
---------
F
R
D
E
R
K
R
Y
C
I
L
K
I
E
G
K
R
P
-----
T
-
P
M
E
N
L
R
G
G
I
Q
N
I
L
Y
R
D
K
E
E
-
D
T
F
H
R
W
L
K
E
S
R
A
E
I
P
I
Q
I
F
D
E
A
Y
R
K
E
N
K
---------------------------------------------------------------------------------------------
101
Fugue
82.04
15%
-31
- C5 -
1M5Y
-
SURA_ECOLI
A:
[25-427]
---
V
D
K
V
A
A
V
V
N
N
G
V
V
L
E
S
D
V
D
G
L
M
Q
S
V
K
L
N
A
A
Q
A
R
Q
Q
L
P
D
D
A
T
L
R
H
Q
I
----------------
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
-----
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
Q
N
N
MT
L
D
----
Q
M
R
S
R
L
A
Y
-
D
G
L
N
Y
N
T
Y
R
N
Q
I
R
K
E
M
I
I
S
E
V
R
N
-----
N
---
E
V
R
R
R
I
T
I
L
P
Q
E
V
E
S
L
A
-----
Q
Q
-
V
------------
T
------
E
L
N
L
S
H
I
L
I
PLPENPT
S
D
Q
V
N
E
A
------------------------------------------------------------------------------------------------------------------------
E
---------------------
S
----------------------
Q
--
A
R
--
A
I
V
D
Q
A
-
R
-
N
------
G
-
A
D
-
F
G
K
L
A
I
A
H
S
A
D
Q
-
Q
A
L
N
G
G
Q
M
G
W
G
R
I
-
Q
E
L
---
P
G
I
F
A
Q
A
L
S
T
A
-
K
K
G
D
I
V
-
G
P
---------
I
R
S
G
-
V
G
F
H
I
L
K
V
N
D
L
R
G
--
E
--
S
K
N
I
S
V
T
E
V
H
A
R
H
I
L
L
K
P
S
P
I
M
T
D
E
Q
A
R
V
K
L
E
Q
I
A
A
D
I
K
S
G
K
T
T
F
A
A
A
A
K
E
F
S
Q
D
P
G
S
A
N
Q
G
G
D
L
GWATPDIFD
P
A
F
R
D
A
L
T
R
LNKG
Q
M
S
A
PVHSSF
G
W
H
L
I
E
LL
D
T
R
N
VD
R
A
Y
R
M
L
M
N
R
K
F
S
E
E
A
A
S
W
M
Q
E
Q
R
A
S
AY
V
K
I
L
S
98
Fugue
81.50
20%
-26
- C6 -
3RFW
-
CBF2_CAMJE
A:
[22-273]
--------------------------
A
T
V
A
T
V
N
G
K
S
I
S
D
T
E
V
S
E
F
F
A
P
M
----------------
L
R
G
Q
D
F
K
T
L
P
D
N
Q
K
K
A
L
I
Q
-----
Q
Y
I
M
Q
D
L
I
L
Q
D
A
K
K
Q
N
L
E
K
---
D
----
P
L
Y
T
K
E
L
D
-
R
A
K
D
A
I
L
V
N
V
Y
Q
E
K
I
L
N
T
I
K
I
D
A
-----
A
---
K
V
K
----
A
F
Y
D
Q
N
K
D
K
Y
-----
V
K
-
P
------------
A
------
R
V
Q
A
K
H
I
L
V
------------
A
T
------------------------------------------------------------------------------------------------------------------------
E
---------------------
K
----------------------
E
--
A
K
--
D
I
I
N
E
L
-
K
-
G
LKG
K
E
L
D
-
A
K
-
F
S
E
L
A
K
E
K
S
I
D
P
G
S
K
N
Q
G
G
E
L
G
W
F
D
Q
-
S
T
M
---
V
K
P
F
T
D
A
A
F
A
L
K
N
G
T
I
T
T
-
T
P
---------
V
K
T
N
-
F
G
Y
H
V
I
L
K
E
N
S
Q
A
--
K
--
G
-
Q
I
K
F
D
E
V
K
Q
G
I
E
N
G
L
K
F
E
E
F
K
K
V
I
N
Q
K
G
Q
D
L
L
N
S
-----------------------
A
K
V
E
Y
K
------------------------------------------------------------------------------
1
PsiBlast_PDB
79.94
56%
-44
- C8 -
1ZK6
-
PRSA_BACSU
A:
[118-205]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
A
S
H
I
L
V
------------
A
D
------------------------------------------------------------------------------------------------------------------------
K
---------------------
K
----------------------
T
--
A
E
--
E
V
E
K
K
L
-
K
-
K
------
G
-
E
K
-
F
E
D
L
A
K
E
Y
S
T
D
S
S
A
S
-
K
G
G
D
L
G
W
F
A
K
E
G
Q
M
---
D
E
T
F
S
K
A
A
F
K
L
K
T
-
G
E
V
S
-
D
P
---------
V
K
T
Q
-
Y
G
Y
H
I
I
---
K
K
T
E
----------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.94
35%
-75
- C8 -
3RFW
-
CBF2_CAMJE
A:
[110-224]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
----
I
D
A
A
K
V
K
A
F
Y
D
Q
N
KD
K
Y
V
K
------------
P
A
-----
R
V
Q
A
K
H
I
L
V
------------
A
T
------------------------------------------------------------------------------------------------------------------------
E
---------------------
K
----------------------
E
--
A
K
--
D
I
I
N
E
L
-
K
-
G
LKG
K
E
L
D
-
A
K
-
F
S
E
L
A
K
E
K
S
I
D
P
G
S
K
N
Q
G
G
E
L
G
W
F
D
Q
-
S
T
M
---
V
K
P
F
T
D
A
A
F
A
L
K
N
G
T
I
T
T
-
T
P
---------
V
K
T
N
-
F
G
Y
H
V
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------
80
HHSearch
78.48
37%
-64
- C8 -
2JZV
-
PRSA_STAAM
A:
[141-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
K
A
S
H
I
L
I
------------
K
V
------------------------------------------------------------------------------------------------------------------------
K
SKKSDKEGLD
D
K
E
A
K
------
Q
----------------------
K
--
A
E
--
E
I
Q
K
E
V
-
S
-
K
D-----
P
-
S
K
-
F
G
E
I
A
K
K
E
S
M
D
T
G
S
A
K
K
D
G
E
L
G
Y
V
L
K
-
G
Q
T
---
D
K
D
F
E
K
A
L
F
K
L
K
-
D
G
E
V
S
-
E
V
---------
V
K
S
S
-
F
G
Y
H
I
I
K
A
D
K
-------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
76.56
36%
-92
- C8 -
3UI5
7
PIN4_HUMAN
A:
[8-97]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
V
R
H
I
L
C
------------
E
K
------------------------------------------------------------------------------------------------------------------------
H
---------------------
G
----------------------
K
--
I
M
--
E
A
M
E
K
L
-
K
-
S
------
G
-
M
R
-
F
N
E
V
A
A
Q
Y
S
E
D
K
A
--
R
Q
G
G
D
L
G
W
M
T
R
-
G
S
M
---
V
G
P
F
Q
E
A
A
F
A
L
----
P
V
S
-
G
M
DK
P
V
F
T
DP
P
V
K
T
K
-
F
G
Y
H
I
I
M
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
76.37
36%
-92
- C8 -
3UI6
8
PIN4_HUMAN
A:
[8-97]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
V
R
H
I
L
C
------------
E
K
------------------------------------------------------------------------------------------------------------------------
H
---------------------
G
----------------------
K
--
I
M
--
E
A
M
E
K
L
-
K
-
S
------
G
-
M
R
-
F
N
E
V
A
A
Q
Y
S
E
D
K
A
--
R
Q
G
G
D
L
G
W
M
T
R
-
G
S
M
---
V
G
P
F
Q
E
A
A
F
A
L
----
P
V
S
-
G
M
D
K
P
V
F
T
DP
P
V
K
T
K
-
F
G
Y
H
I
I
M
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.31
45%
-74
- C8 -
2RQS
-
?
A:
[10-94]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
C
S
H
I
L
V
------------
K
K
------------------------------------------------------------------------------------------------------------------------
Q
---------------------
G
----------------------
E
--
A
L
--
A
V
Q
E
R
L
-
K
-
A
------
G
-
E
K
-
F
G
K
L
A
K
E
L
S
I
D
G
G
S
A
K
R
D
G
S
L
G
Y
F
G
R
-
G
K
M
---
V
K
P
F
E
D
A
A
F
R
L
Q
-
V
G
E
V
S
-
E
P
---------
V
K
S
E
-
F
G
Y
H
V
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
76.07
34%
-68
- C8 -
1M5Y
-
SURA_ECOLI
A:
[284-389]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
H
A
R
H
I
L
L
K
P
SPIMT-----
D
E
------------------------------------------------------------------------------------------------------------------------
Q
---------------------
A
----------------------
R
--
V
K
L
E
Q
I
A
A
D
I
-
K
-
S
------
G
-
K
T
T
F
A
A
A
A
K
E
F
S
Q
D
P
G
S
A
N
Q
G
G
D
L
G
W
A
T
P
-
D
I
F
---
D
P
A
F
R
D
A
L
T
R
L
-
N
K
G
Q
M
S
-
A
P
---------
V
H
S
S
-
F
G
W
H
L
I
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
75.21
35%
-78
- C8 -
4G2P
3
?
A:
[8-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
H
A
R
H
I
L
L
K
P
S
PIMN-----
D
Q
------------------------------------------------------------------------------------------------------------------------
Q
---------------------
A
----------------------
R
--
L
K
L
E
E
I
A
A
D
I
-
K
-
S
------
G
-
K
T
T
F
A
A
A
A
K
E
Y
S
Q
D
P
G
S
A
N
Q
G
G
D
L
G
W
A
T
P
-
D
I
F
---
D
P
A
F
R
D
A
L
T
K
L
-
H
K
G
Q
I
S
-
A
P
---------
V
H
S
S
-
F
G
W
H
L
I
E
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------
77
HHSearch
74.24
28%
-45
- C8 -
2PV1
1
A:
[2-103]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
N
L
S
H
I
L
I
------------
P
L
PENPT
S
D
Q
V
N
E
A
------------------------------------------------------------------------------------------------------------
E
---------------------
S
----------------------
Q
--
A
R
--
A
I
V
D
Q
A
-
R
-
N
------
G
-
A
D
-
F
G
K
L
A
I
A
H
S
A
D
Q
-
Q
A
L
N
G
G
Q
M
G
W
G
R
I
-
Q
E
L
---
P
G
I
F
A
Q
A
L
S
T
A
K
-
K
G
D
I
V
-
G
P
---------
I
R
S
G
-
V
G
F
H
I
L
K
V
N
D
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------------
84
HHSearch
73.66
30%
-69
- C8 -
3TC5
2
PIN1_HUMAN
A:
[56-166]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
------
R
V
R
C
S
H
L
L
V
------------
K
H
------------------------------------------------------------------------------------------------------------------------
S
QSRRPSSWRQEKITRT
K
E
E
A
L
E
----------------------
L
--
I
N
--
G
Y
I
Q
K
I
-
K
-
S
------
G
E
E
D
-
F
E
S
L
A
S
Q
F
S
D
C
S
-
S
A
K
A
R
G
D
L
G
A
F
S
R
-
G
Q
M
---
Q
K
P
F
E
D
A
S
F
A
L
R
-
T
G
E
M
S
-
G
P
---------
V
F
T
D
-
S
G
I
H
I
I
L
R
T
E
-------------------------------------------------------------------------------------------------------------------------------------------------------
75
HHSearch
73.25
30%
-50
- C8 -
1JNS
-
PPIC_ECOLI
A:
[3-91]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
A
A
L
H
I
L
V
------------
K
E
------------------------------------------------------------------------------------------------------------------------
E
---------------------
K
----------------------
L
--
A
L
--
D
L
L
E
Q
I
-
K
-
N
------
G
-
A
D
-
F
G
K
L
A
K
K
H
S
I
C
P
-
S
G
K
R
G
G
D
L
G
E
F
R
Q
-
G
Q
M
---
V
P
A
F
D
K
V
V
F
S
C
P
-
V
L
E
P
T
-
G
P
---------
L
H
T
Q
-
F
G
Y
H
I
I
K
V
L
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------
78
HHSearch
72.91
24%
-59
- C8 -
3GPK
2
?
A:
[6-105]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
------
E
Y
R
I
G
E
I
F
L
------------
A
A
------------------------------------------------------------------------------------------------------------------------
T
EEN
K
P
Q
V
F
-------------
A
----------------------
N
--
A
E
--
K
I
V
E
Q
L
-
K
-
Q
------
G
-
G
S
-
F
V
A
Y
A
R
Q
Y
S
E
A
S
-
T
A
A
V
G
G
D
L
G
W
I
R
L
-
A
Q
L
---
P
T
E
L
A
T
T
A
A
S
M
G
-
P
G
Q
L
A
-
G
P
---------
V
E
I
R
-
G
G
F
S
I
L
Y
L
I
D
K
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
72.65
40%
-41
- C8 -
2JZV
-
PRSA_STAAM
A:
[161-242]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
------------
D
K
------------------------------------------------------------------------------------------------------------------------
E
---------------------
A
----------------------
K
Q
K
A
E
--
E
I
Q
K
E
V
S
K
-
D
------
P
-
S
K
-
F
G
E
I
A
K
K
E
S
M
D
T
G
S
A
K
K
D
G
E
L
G
Y
V
L
K
-
G
Q
T
---
D
K
D
F
E
K
A
L
F
K
L
K
D
-
G
E
V
S
-
E
V
---------
V
K
S
S
-
F
G
Y
H
I
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------
72
HHSearch
72.21
23%
-28
- C8 -
1YW5
-
?
A:
[11-177]
--------------------------------------------------------------------------------------------------------------------
N
W
T
I
R
V
S
R
-
S
H
-
N
K
E
Y
F
L
N
Q
S
T
N
E
S
S
W
D
P
P
-------------
Y
----
G
T
D
K
E
V
L
N
A
Y
-----
I
A
K
F
K
N
N
GY
K
P
L
V
N
ED
G
------
Q
V
R
V
S
H
L
L
I
------------
K
N
------------------------------------------------------------------------------------------------------------------------
N
---------------------
Q
SRKPKSWKSPDGISRT
R
D
E
S
I
Q
I
--
L
K
--
K
H
L
E
R
I
-
L
-
S
------
G
E
V
K
-
L
S
E
L
A
N
T
E
S
D
C
S
-
S
H
D
R
G
G
D
L
G
F
F
S
K
-
G
Q
M
---
Q
P
P
F
E
E
A
A
F
N
L
H
-
V
G
E
V
S
-
N
I
---------
I
E
T
N
-
S
G
V
H
I
L
Q
R
T
G
-------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
72.20
20%
-29
- C7 -
3RGC
-
?
A:
[22-271]
--------------------------
A
I
A
V
V
V
D
K
E
P
I
T
T
Y
D
I
D
Q
T
M
K
A
L
KI--------------
D
R
N
K
A
L
G
V
L
I
N
E
K
M
E
I
S
Q
M
K
Q
L
G
I
V
V
N
D
L
E
L
D
D
A
I
N
K
M
L
A
Q
N
K
---
T
T
L
N
-
A
F
K
A
N
L
K
S
----
S
Y
E
Q
F
R
T
N
F
K
K
D
L
E
K
R
K
L
Y
E
K
I
A
S
M
A
---
K
T
D
----
F
S
D
D
G
A
K
K
F
F
-----
E
Q
N
K
------------
D
K
F
T
F
Y
T
Q
I
N
A
N
I
Y
L
S
------------
N
N
------------------------------------------------------------------------------------------------------------------------
P
---------------------
Q
----------------------
T
--
L
E
--
N
I
K
N
T
K
-
K
---------------
T
I
L
K
P
---------
Q
N
---
A
S
L
N
T
-
S
N
A
---
D
P
R
L
L
G
L
L
S
Q
I
P
-
V
G
S
F
S
-
P
V
---------
L
N
G
K
-
N
G
Y
E
L
Y
E
V
K
S
K
D
G
--
T
QT
P
-
E
Y
E
Q
V
K
N
E
V
L
N
A
Y
V
S
E
Q
R
Q
-
N
F
I
Q
D
Y
F
D
K
L
R
S
K
I
N
I
E
Y
L
R
-----------------------------------------------------------------------------------------------------