@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0114: (2015-11-28 )
MKNMMKYISELTTLIALAGLMVIITLINPNFLTTNNLLNLLLQVTANGFIAFGMTFVILTGGIDLSVGSILALSSALTAGLIGHGVPVGIAIVLSVALGGILGMLNGLFISYGKLAPFIVTLATMTIFRGATLVYSNGNPITAGLSDSFLFQFLGQGYIVGIPFPVILMFLTFIILYILLHKTAFGKSVYALGGNEKAAYISGIKLNKVKIIIYTISGIMASISGLIITSRLSSAQPTAGASYEMDAIAAVVLGGTSLSGGKGRIIGTLIGALIIGVLNNGLNIIGVSAFWQQVVKGIVILMAVLLDRFKVAK
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------.....-....10-.........20...--------------.....30.....---...40...----...---..50..-----.--...-..60.-------.-......70....--..-.------.80-----....------------....90.......---.100.......--110.......120-.......------130.----------......140..-.....150.----......160--....-----------...-.170--....-.....180.....---..190......-.200-..-.......210-.....------..---------------220.....----------------------..230-......-..-------------------240----------..-----..---------....250.......--260-......-----...270-----------...--.----------.....-280.......---------.290---------...-.....300.......310.-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------M
K
N
M
M
-
K
Y
I
S
E
--
L
T
T
L
I
A
L
A
G
L
M
V
I
I
--------------
T
LINPNFL
T
T
N
N
---
L
L
N
L
L
L
Q
V
----TAN---
G
F
I
A
F
G
-----
M
--
T
F
V
-
I
L
TGG-------I-DL
S
V
G
S
I
L
A
L
S
S
--
A
L
-
T
------
A
G
L
-----IGHG------------
V
P
V
G
I
A
I
V
L
S
V
A
L
---
G
G
I
L
G
M
L
N
G
L
F
--
I
S
YGK
L
A
P
F
I
V
T
L
-
A
T
M
T
I
FR------G
A
T
L
----------
V
YSNGNPITAG-L
S
D
S
F
L
F
Q
F
----LGQ
G
Y
I
VG---I
P
F
P
-----------
V
I
L
-
M
F
----
L
T
F
I
-
I
L
Y
I
L
L
HKTAFG
K
---
S
V
Y
A
LGGNE
K
A
-
A
Y
---
I
S
-
G
I
K
L
N
K
V
K
I
I
-
I
Y
T
I
S
------
G
I
---------------
M
A
S
I
S
G
L
I
----------------------
I
T
SR--LSSAQP-TA-------------------GA-----------SY-----
E
M
---------
D
A
I
A
A
V
V
LGGTSLS--G---GKG
R
I
I
-----
G
T
L
I
-------------
G
A
L
--
I
----------
I
G
V
L
N-NG-L
N
I
I
G
V
S
---------
A
F
W
----------
Q
Q
V
-
V
K
G
I
V
I
L
M
A
V
L
L
D
R
FKVAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
72.50
17%
-83
- C5 -
3WFS
2
?
C:
[23-388]
--------------------------------------------------------------------------------------------------------------------------------------------
L
N
F
Y
L
-
S
Y
F
D
D
--
V
A
K
V
L
P
R
E
H
Y
C
F
I
V
GGWVRDRILGEPVG
Y
N
I
D
V
D
F
L
T
T
A
D
---
P
V
E
L
A
K
N
F
----
A
K
R
IGG
H
F
F
V
F
E
-----
P
--
T
I
A
-
S
V
V
L
H
LPPYRYR
F
-
D
F
S
P
L
K
G
K
D
L
E
K
--
A
L
-
I
------
E
D
L
KERDF
T
A
N
A
------------
I
A
V
N
L
D
D
V
L
T
I
V
Y
DPT
G
G
I
K
D
L
E
Q
G
L
L
RP
V
S
I
E
N
L
K
R
D
P
V
------
R
V
L
R
------
G
F
R
I
----------
A
I
E
K
N
L
Q
L
T
------
E
D
F
Y
E
F
----
V
K
E
D
P
R
I
V
---
L
K
S
A
-----------
V
E
R
-
I
T
----
H
E
L
F
-
K
I
M
K
E
K
T
A
H
K
V
I
R
---
E
L
Y
E
Y
G
V
L
E
A
I
I
P
E
---
I
G
-
R
L
R
E
V
K
D
P
L
D
-
E
H
T
L
K
------
T
L
---------------
E
Y
L
E
Q
V
I
E
----------------------
D
R
A
K
--
Y
L
S
A
E
L
-
L
E
NFGKKRVLGEFTDVELLKW
G
A
LFHDIGKPQTT
F
Y
-----
E
H
---------
D
K
V
G
A
Q
I
V
R
E
I
G
E
R
--
L
---
R
W
G
D
E
A
-----
T
E
F
V
-------------
A
K
L
--
V
RHHLRPFFLR
E
A
F
K
K
-
G
E
-
L
K
R
R
G
M
A
---------
N
F
W
----------
R
E
C
-
G
D
I
A
P
H
L
F
L
L
S
I
A
D
A
M
A
S
G
DEEEDIKALMETIAELESFNRNEMK----------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
71.78
14%
-162
* C4 *
1GEQ
-
TRPA_PYRFU
A:
[1-248]
---------------------------------------------------------------------------------------------------------------------------------------------------
M
F
K
---------
D
G
S
L
I
P
Y
L
--------------
T
A
G
D
P
D
K
Q
S
T
L
N
---
F
L
L
A
L
D
E
Y
-----
A
G
----
A
I
E
L
G
-----
I
--
P
F
S
D
P
I
A
D
G
-------
K
-
T
I
Q
E
S
H
Y
R
A
L
K
N
--
G
F
-
K
------------------------------------------
L
---
R
E
A
F
W
I
V
K
E
F
R
--
R
H
S
-
S
T
P
I
V
L
M
T
Y
-
Y
N
P
I
Y
R
A
------
G
------------------------------
V
R
N
F
----
L
A
E
A
K
A
S
G
---
V
D
------------------------
G
I
L
-
V
V
D
L
P
V
F
H
A
K
E
F
T
---
E
I
A
R
E
E
G
I
K
T
V
-
F
L
---
A
A
P
N
T
P
D
E
R
L
K
V
I
-
D
D
M
T
T
------
G
F
---------------
V
Y
L
V
S
L
Y
---------------------------EI
P
K
T
A
Y
D
-
L
L
-------------------
R
R
-----------
A
K
-----
R
I
---------
C
R
N
K
V
A
V
G
F
G
V
S
K
R
--
E
---
H
V
V
S
L
L
K
E
GAN
G
V
V
V
-------------
G
S
A
--
L
----------
V
K
I
I
G
-
E
K
-------------------
G
----------
R
E
A
-
T
E
F
L
K
K
K
V
E
E
L
L
G
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
64.31
15%
-125
- C4 -
4XDN
5
SCC4_YEAST
A:
[24-640]
G
D
K
L
S
I
S
Q
V
Y
H
L
A
Q
E
Y
R
D
H
A
Y
S
I
A
NKIGS
E
E
G
L
K
Q
Y
Y
G
L
M
N
M
S
I
Q
M
F
Q
L
L
K
T
KCTLS
V
L
E
D
S
K
V
T
F
E
M
V
E
L
L
I
Q
ETYN
F
D
L
A
E
L
Y
I
S
S
L
K
E
R
L
Q
T
H
QSDTDL
V
E
E
I
M
R
C
E
F
L
L
L
H
D
L
P
L
M
R
DS
K
F
H
Y
K
I
A
L
R
N
C
N
E
L
V
Q
Y
M
V
N
L
Q
D
E
L
Y
Q
N
--
W
A
S
V
F
Q
Y
V
G
V
M
L
C
I
--------------
K
L
-
K
Q
H
R
R
V
K
T
S
---
F
H
G
L
L
S
Q
C
REKS
Q
W
K
---
W
F
L
N
L
C
-----
Y
--
V
N
Y
-
L
L
N
E
R
-------
F
-
P
I
P
E
D
A
L
Q
E
L
R
S
TE
L
H
-
T
------
V
G
P
-----
E
L
Y
A
------------
W
K
L
A
L
E
M
V
I
Q
L
C
K
---
D
G
---------------
N
I
T
D
H
L
N
E
F
-
K
N
F
F
D
T
N
------
K
Q
S
L
----------
V
T
N
E
G
K
G
C
V
I
K
-
I
M
P
R
I
A
L
K
V
----------------
E
L
P
-----------
M
I
F
-
H
Y
----
K
E
L
K
-
N
I
L
L
L
L
Q
S
V
S
Y
I
V
---
N
C
Y
D
E
K
G
N
F
S
R
-
K
F
---
L
P
-
K
V
Y
S
T
T
Q
K
L
I
-
K
N
I
A
A
------
G
------------------
G
V
S
M
N
E
----------------------
L
D
S
R
--
I
Q
T
Y
K
S
-
I
L
-------------------
E
F
-----------
C
E
-----
F
Y
---------
K
V
W
E
Q
T
L
L
K
G
A
V
V
L
--
G
PSP
G
Y
V
R
L
L
-----
Q
A
M
K
-------------
V
Q
F
--
E
----------
G
G
G
A
V
-
E
E
-
Y
T
R
L
A
Q
S
---------
G
G
T
----------
S
S
E
-
V
K
M
I
S
L
L
N
C
Y
T
V
Q
A
A
R
V
S
R
CSGDK
Q
G
E
L
V
E
Q
C
N
K
V
W
L
Q
V
E
K
L
L
Q
E
T
DLQFN
P
I
W
E
C
T
V
T
I
L
W
L
F
S
H
F
EPFSWNPLPCS
D
K
Q
R
A
E
Y
V
S
K
L
R
E
F
Y
S
S
N
KFVNRFKLKKA
L
L
L
Q
I
L
V
N
Y
L
G
G
R
M
LEHD
L
G
E
I
Y
A
I
S
A
K
C
F
D
M
C
R
QQGGM
R
K
V
Q
Y
V
I
G
I
W
H
L
M
N
C
T
V
A
MR
G
K
D
V
A
L
T
N
A
K
L
E
A
L
V
K
Q
I
T
S
20
Fugue
64.21
12%
-132
- C5 -
4YLR
1
TTLL7_HUMAN
A:
[9-453]
--------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
A
N
-
V
A
G
T
K
--
F
E
I
V
R
L
V
I
D
E
M
G
F
M
--------------
K
T
P
D
E
D
E
T
S
N
L
I
---
W
C
D
S
A
V
Q
Q
----
E
K
I
---
S
E
L
Q
N
Y
-----
Q
--
R
I
N
-
H
F
P
G
M
-------
G
-
E
I
C
R
K
D
F
L
A
R
N
M
--
T
K
-
M
------
I
K
S
-----
R
P
L
D
------------
Y
T
F
V
P
R
T
W
I
F
P
A
------------------
E
Y
T
Q
F
Q
N
Y
V
K
E
L
-
K
K
K
R
--
K
------
Q
K
T
F
----------
I
V
K
P
I
S
L
I
R
N
S
-
Q
D
H
L
I
V
Q
E
Y
----
I
E
K
P
F
L
M
E
G
Y
K
F
D
L
R
-----------
I
Y
I
-
L
V
----
T
S
C
D
-
P
L
K
I
F
L
Y
H
D
G
L
V
R
M
G
T
E
K
Y
I
P
G
S
K
R
S
I
-
K
W
---
F
T
-
E
F
L
Q
A
N
Q
-----
H
D
V
A
------
K
F
---------------
W
S
D
I
S
E
L
V
----------------------
V
K
T
---
L
I
V
A
E
P
-
H
V
-------------------
L
H
-----------
A
Y
-----
R
M
C
R
PGQPPGS
E
S
V
C
F
E
V
L
G
F
D
I
L
L
--
D
---
R
K
L
K
P
W
-----
L
L
Q
I
NRAPSFGTDQ
K
I
D
Y
D
V
--
K
----------
R
G
V
L
L
-
N
A
-
L
K
L
L
N
I
R
---------
T
M
G
NYRRIYPPED
K
A
L
-
L
E
K
Y
E
N
L
L
A
V
A
F
Q
T
F
L
S
G
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
63.17
9%
-125
- C4 -
3VK5
2
?
A:
[21-273]
--------------------------------------------------------------------------------------------------------------------------------------------
A
P
P
L
W
-
R
P
G
R
V
--
L
A
R
L
R
E
H
Q
P
G
--
P
V
--------------
H
I
I
D
P
F
K
V
P
V
T
E
---
A
V
E
K
A
A
E
L
----
T
R
L
---
G
-------------
F
A
A
-
V
L
L
A
S
-----------
T
D
Y
E
S
F
E
S
H
M
--
E
P
-
Y
------
V
A
A
-----
V
K
A
A
------------
T
P
L
P
V
V
L
H
F
P
P
R
P
---
G
A
G
F
P
V
V
R
G
A
D
--------
A
L
L
L
P
A
L
-
L
G
S
G
D
D
Y
------
F
V
W
K
----------
S
F
L
E
T
L
A
A
F
P
G
R
I
P
R
E
E
W
P
E
L
----
L
L
T
V
A
L
T
F
---
G
E
D
P
-----------
R
T
G
-
D
L
----
L
G
T
V
-
P
V
S
T
A
S
T
E
E
I
D
R
Y
---
L
H
V
A
R
A
F
G
F
H
M
-
V
Y
---
L
Y
----------------------------------------------------------------------
S
R
N
E
--
H
V
P
P
E
V
-
V
R
-------------------
H
F
-----------
R
K
-----
G
L
---------
G
P
D
Q
V
L
F
V
S
G
N
V
R
S
--
G
---
R
Q
V
T
E
Y
-----
L
D
S
-------------------------------------
G
-
A
D
Y
V
G
F
A
---------
G
A
L
----------
E
Q
---
P
D
W
R
S
A
L
A
E
I
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
54.97
14%
-101
- C6 -
1FQY
-
AQP1_HUMAN
A:
[8-233]
--------------------------------------------------------------------------------------------------------------------------------------------
K
L
F
W
R
-
A
V
V
A
E
--
F
L
A
T
T
L
F
V
F
I
S
I
G
S
--------------
A
L
G
F
K
Y
P
V
G
N
N
Q
---
T
A
V
Q
D
N
V
K
----
V
S
L
---
A
F
G
L
S
I
-----
A
--
T
L
A
-
Q
S
V
G
H
-------
I
-
S
----------------------------------
G
------------
A
H
L
N
P
A
V
T
L
G
L
L
L
---
S
C
Q
I
S
I
F
R
A
L
M
--
Y
I
I
A
Q
C
V
G
A
I
V
A
T
-
A
I
L
S
G
I
T
------
S
S
L
T
----------
G
N
S
L
G
R
N
------------------------------------------------------------------------------
D
L
A
D
G
V
N
S
-
G
Q
---
G
L
-
G
I
E
I
I
G
T
L
Q
L
-
V
L
C
V
L
------
A
T
---------------
T
D
R
R
R
--------------------------
R
D
L
--
G
G
S
A
P
L
-
A
I
-------------------
G
L
-----------
S
V
-----
A
L
---------
G
H
L
L
A
I
D
Y
T
G
C
G
I
N
----------------------------------
P
A
R
--
S
----------
F
G
S
A
V
-
I
T
-
H
N
F
S
N
H
W
---------
I
F
W
----------
V
G
P
-
F
I
G
G
A
L
A
V
L
I
Y
D
F
I
L
A
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
53.55
28%
-157
- C7 -
3NI2
1
?
A:
[235-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
A
L
N
S
--
I
M
-
L
------
C
G
L
-----
R
V
-
G
------------
A
P
--
I
L
I
M
P
K
F
E
I
---
G
S
L
L
G
L
I
E
K
Y
K
--
V
S
I
A
P
V
V
P
P
V
M
-----
M
S
I
A
K
------
S
P
D
L
DKHDLSSLR
M
I
K
S
G
G
A
P
L
G
K
E
-
L
E
D
T
V
R
A
K
F
PQ
A
R
L
G
Q
G
Y
G
M
T
---
E
A
G
P
-----------
V
L
A
-
M
C
----
L
A
F
A
-
K
E
P
F
D
I
K
P
G
A
C
G
T
---
V
V
R
N
A
E
M
K
I
V
D
-
P
E
---
T
G
-
A
S
L
P
R
N
Q
P
G
E
-
I
C
I
R
G
------
D
Q
---------------
I
M
K
G
Y
L
N
D
----------------------
P
E
A
T
--
S
R
T
I
D
K
-
E
G
-------------------
W
L
-----------
H
T
-----
G
D
---------
I
G
Y
I
D
D
D
D
E
L
F
I
V
D
--
R
---
L
K
E
L
I
K
-----
Y
K
G
F
-------------
Q
V
A
--
P
----------
A
E
L
E
A
-
L
L
-
I
A
H
P
E
I
S
---------
D
A
A
----------
V
V
G
-
L
K
D
E
D
A
G
E
V
P
V
A
F
V
V
K
S
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
53.21
28%
-152
- C7 -
3A9V
1
?
A:
[235-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
A
L
N
S
--
I
M
-
L
------
C
G
L
-----
R
V
-
G
------------
A
P
--
I
L
I
M
P
K
F
E
I
---
G
S
L
L
G
L
I
E
K
Y
K
--
V
S
I
A
P
V
V
P
P
V
M
-----
M
S
I
A
K
------
S
P
D
L
DKHDLSSLR
M
I
K
S
G
G
A
P
L
G
K
E
-
L
E
D
T
V
R
A
K
F
PQ
A
R
L
G
Q
G
Y
G
M
T
---
E
A
G
P
-----------
V
L
A
-
M
C
----
L
A
F
A
-
K
E
P
F
D
I
K
P
G
A
C
G
T
---
V
V
R
N
A
E
M
K
I
V
D
-
P
E
---
T
G
-
A
S
L
P
R
N
Q
P
G
E
-
I
C
I
R
G
------
D
Q
---------------
I
M
K
G
Y
L
N
D
----------------------
P
E
A
T
--
S
R
T
I
D
K
-
E
G
-------------------
W
L
-----------
H
T
-----
G
D
---------
I
G
Y
I
D
D
D
D
E
L
F
I
V
D
--
R
---
L
K
E
L
I
K
-----
Y
K
G
F
-------------
Q
V
A
--
P
----------
A
E
L
E
A
-
L
L
-
I
A
H
P
E
I
S
---------
D
A
A
----------
V
V
G
-
L
K
D
E
D
A
G
E
V
P
V
A
F
V
V
K
S
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
52.75
19%
-64
- C5 -
4OY2
1
TAF1_YEAST
A:
[10-502]
--------------------------------------------------------------------------------------------------------------------------------NL
N
I
Q
H
S
Q
P
A
I
N
L
Q
S
P
F
-
Y
K
V
A
V
--
P
R
Y
Q
L
R
H
F
H
R
E
N
F
G
--------------
S
H
I
R
P
G
T
K
I
V
F
S
---
K
L
K
A
R
K
R
K
----
R
D
K
---
G
K
D
V
K
E
-----
S
F
S
T
S
Q
-
D
L
T
I
G
DTA
P
V
Y
-
L
M
E
Y
S
E
Q
T
P
V
A
L
S
K
--
F
G
M
A
------
N
K
L
-----
I
N
Y
Y
R
K
ANEQDT
L
R
P
K
L
P
V
G
E
T
H
V
L
G
V
Q
D
---
K
S
P
F
W
N
F
G
--
F
--
V
E
P
G
H
I
V
P
T
L
Y
N
N
M
I
R
A
P
V
F
K
H
D
I
SGT
D
F
L
L
----------
T
K
S
S
G
F
----
G
-
I
S
N
R
F
Y
L
R
N
----
I
N
H
L
F
T
V
G
---
Q
T
F
P
V
E
E
I
P
G
PNS
R
K
V
T
S
M
K
A
----
T
R
L
K
M
I
I
Y
R
I
L
N
H
N
H
S
K
A
---
I
S
I
D
P
I
A
K
H
F
P
-
D
Q
---
D
Y
-
G
Q
N
R
Q
K
V
K
E
F
M
K
Y
Q
R
D
------
G
P
EKG
L
W
R
L
KDD
E
K
L
L
D
N
E
A
V
K
S
L
I
----------------------
T
P
E
Q
--
I
S
Q
V
E
S
M
S
Q
-------------------
G
L
-----------
Q
F
-----
Q
E
---------
D
N
E
A
Y
N
F
--
D
S
K
L
K
--
S
---
L
E
E
N
L
L
-----
P
W
N
I
-------------
T
K
N
--
F
----------
I
N
S
T
Q
M
R
A
M
I
Q
I
H
G
V
G
DPTGCGEGF
S
F
L
----------
K
T
S
M
K
H
S
Y
N
V
A
Q
Q
Q
K
A
Y
D
E
E
I
A
K
T
W
Y
T
H
T
K
S
L
S
ISNPFEEMTNPDEIN
Q
T
N
K
H
VKTDRDDK
K
I
L
K
I
V
R
K
K
RDENG
I
I
Q
R
Q
T
I
F
I
RD
P
R
V
I
Q
G
Y
I
K
I
K
E
Q
D
K
EDVN-------------------------------------------------------------------------------------
24
Fugue
51.28
15%
-84
* C6 *
1MIQ
-
?
B:
[76-327]
-------------------------------------------------------------------------------------------------------------------------------TE
H
L
T
L
A
F
K
I
E
R
P
Y
D
K
V
L
-
K
T
I
S
K
KN
L
K
N
Y
I
K
E
T
F
N
F
F
K
S
--------------
G
Y
M
K
Q
N
Y
L
G
S
E
N
D
V
I
E
L
D
D
V
A
N
I
----
M
F
Y
---
G
E
G
E
V
G
DNHQ
K
F
--
M
L
I
-
F
D
T
G
S
-------
A
-
N
L
W
V
P
S
K
K
C
N
S
S
--
G
C
-
S
IKNLYD
S
S
K
-----
S
K
S
Y
------------
E
K
D
G
T
K
V
D
I
T
Y
G
S
---
G
T
V
K
G
F
F
S
K
D
L
--
V
T
L
G
H
-------
L
-
S
M
P
Y
K
F
I
------
E
V
T
D
----------
T
D
D
L
E
P
I
Y
S
S
V
-
E
F
D
G
I
L
G
L
G
----
W
K
D
L
S
I
G
S
---
I
D
P
I
-----------
V
V
E
-
L
K
N
Q
NK
I
D
N
A
-
L
F
T
F
Y
L
P
V
H
D
V
H
A
---
G
Y
L
T
I
G
G
I
E
E
K
-
F
Y
E
G
N
I
T
-
Y
E
K
L
N
H
D
L
Y
W
-
Q
I
D
L
D
------
V
H
---------------
F
G
K
Q
T
M
E
K
----------------------
A
N
V
I
--
V
D
S
G
T
T
-
T
I
-------------------
T
A
-----------
P
S
-----
E
F
---------
L
N
K
F
F
A
N
L
N
V
I
K
V
P
--
F
---
L
P
F
Y
V
T
-----
T
C
D
N
-------------
K
E
M
P
T
L
----------
E
F
K
S
A
-
N
N
-
T
Y
T
L
E
P
E
---------
Y
Y
M
----------
N
P
I
-
L
E
V
D
D
T
L
C
M
I
T
M
L
P
V
D
I
D
S
N
T
F
I
LG
D
P
F
M
R
K
Y
F
T
V
F
D
YDKE
S
V
G
F
A
I
A
K
N----------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.60
33%
-204
- C7 -
2PN1
-
?
A:
[56-103]
----------------------------------------------------------------------------------------------------------------------------------------------
D
E
V
-
E
Y
I
D
H
--
L
L
T
L
C
Q
D
E
G
V
T
A
L
L
--------------
T
L
I
D
P
E
----------
L
G
L
L
A
Q
A
----
T
E
R
----
F
Q
A
I
G
-----
V
--
T
V
I
-
V
S
P
Y
A
-------
A
-
C
E
L
C
F
D
K
Y
T
M
Y
E
--
Y
C
-
L
------
R
Q
G
-----
I
A
H
A
------------
R
T
Y
A
T
M
A
S
F
E
E
A
L
---
A
A
G
E
V
Q
L
P
V
F
V
--
K
P
R
N
G
D
L
I
V
Q
E
L
L
-
V
G
Q
E
L
G
V
------
D
A
Y
V
----------
D
L
I
S
G
K
V
T
S
I
F
-
I
K
E
K
L
T
M
R
A
----
G
E
T
D
K
S
R
S
---
V
L
R
D
-----------
D
V
F
-
E
L
----
V
E
H
V
-
L
D
G
S
G
L
V
G
P
L
D
F
D
---
L
F
D
V
A
G
T
L
Y
L
S
-
E
I
---
N
P
-
R
F
G
G
G
Y
P
H
A
Y
-
E
C
G
V
N
------
F
P
---------------
A
Q
L
Y
R
N
L
M
----------------------
H
E
I
N
--
V
P
Q
I
G
Q
-
Y
L
-------------------
D
D
-----------
I
Y
-----
M
L
---------
K
H
D
T
V
T
L
I
S
A
A
E
L
Q
--
K
---
I
K
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.34
28%
-184
- C7 -
3A9U
-
?
A:
[235-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
A
L
N
S
--
I
M
-
L
------
C
G
L
-----
R
V
-
G
------------
A
P
--
I
L
I
M
P
K
F
E
I
---
G
S
L
L
G
L
I
E
K
Y
K
--
V
S
I
A
P
V
V
P
P
V
M
-----
M
S
I
A
K
------
S
P
D
L
DKHDLSSLRM
I
K
S
-------
E
-
L
E
D
T
V
R
A
K
F
P
Q
A
R
L
G
Q
G
Y
G
M
T
---
E
A
G
P
-----------
V
L
A
-
M
C
----
L
A
F
A
-
K
E
P
F
D
I
K
P
G
A
C
G
T
---
V
V
R
N
A
E
M
K
I
V
D
-
P
E
---
T
G
-
A
S
L
P
R
N
Q
P
G
E
-
I
C
I
R
G
------
D
Q
---------------
I
M
K
G
Y
L
N
D
----------------------
P
E
A
T
--
S
R
T
I
D
K
-
E
G
-------------------
W
L
-----------
H
T
-----
G
D
---------
I
G
Y
I
D
D
D
D
E
L
F
I
V
D
--
R
---
L
K
E
L
I
K
-----
Y
K
G
F
-------------
Q
V
A
--
P
----------
A
E
L
E
A
-
L
L
-
I
A
H
P
E
I
S
---------
D
A
A
----------
V
V
G
-
L
K
D
E
D
A
G
E
V
P
V
A
F
V
V
K
S
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.36
27%
-51
* C8 *
2QQM
2
NRP1_HUMAN
A:
[288-389]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
K
I
T
-
D
Y
P
C
S
------
G
M
---------------
L
G
M
V
S
G
L
I
SDSQITSSNQGDRNWMPENIRL
V
T
S
R
--
S
G
W
A
L
P
-
P
A
-------------------
P
H
-----------
S
Y
IN
E
W
L
Q
I
---------
D
L
G
E
E
K
I
V
R
G
I
I
I
Q
--
G
---
G
K
H
R
E
N
-----
K
V
F
M
-------------
R
K
F
--
K
----------
I
G
Y
S
N
-
N
G
-
S
D
W
K
M
I
M
---------
D
D
S
----------
K
R
K
-
A
K
S
F
E
G
N
N
N
Y
D
T
P
E
L
R
T
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.01
27%
-40
- C8 -
2QQI
1
A:
[156-257]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
K
I
T
-
D
Y
P
C
S
------
G
M
---------------
L
G
M
V
S
G
L
I
SDSQITSSNQGDRNWMPENIRL
V
T
S
R
--
S
G
W
A
L
P
-
P
A
-------------------
P
H
-----------
S
Y
I
N
E
W
L
Q
I
---------
D
L
G
E
E
K
I
V
R
G
I
I
I
Q
--
G
---
G
K
H
R
E
N
-----
K
V
F
M
-------------
R
K
F
--
K
----------
I
G
Y
S
N
-
N
G
-
S
D
W
K
M
I
M
---------
D
D
S
----------
K
R
K
-
A
K
S
F
E
G
N
N
N
Y
D
T
P
E
L
R
T
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
37.78
23%
16
* C5 *
2L8T
-
?
A:
[2-72]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
---
T
K
Y
E
L
N
N
T
K
K
V
-
A
N
---
A
F
-
G
L
N
E
E
D
T
N
L
L
-
I
N
A
V
D
------
L
D
---------------
I
K
N
N
M
Q
-
E
----------------------
I
S
S
E
--
L
Q
Q
S
E
Q
-
S
K
-------------------
Q
K
-----------
Q
Y
-------------------------
G
T
T
L
Q
NL
A
---
K
Q
N
R
I
I
-----
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
34.79
20%
-35
- C7 -
2NQ2
-
Y1471_HAEIN
A:
[214-253]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
W
---
R
L
N
L
L
S
L
D
E
K
E
-
A
K
---
A
L
-
G
V
K
M
A
P
L
R
W
L
-
V
I
F
L
S
------
G
S
---------------
L
V
A
C
Q
V
A
I
----------------------
S
G
S
I
--
G
W
V
G
L
I
-
I
P
-------------------
H
L
-----------
S
R
-----
M
L
---------
V
G
A
N
H
Q
S
L
L
P
C
T
M
L
--
V
---
G
A
T
Y
M
L
-----
L
V
D
N
-------------
V
A
R
--
S
----------
L
S
D
A
E
-
I
P
-
I
S
I
L
T
A
L
---------
I
G
A
----------
P
L
F
-
G
V
L
V
Y
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.11
30%
27
- C7 -
4HR3
-
?
A:
[295-347]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
R
T
A
F
G
K
---
P
L
V
N
L
G
G
N
R
E
R
-
I
A
---
D
A
-
R
I
A
I
N
Q
T
R
L
L
-
V
L
H
A
A
W
L
L
D
T
V
G
I
---------------
M
G
A
L
S
A
V
S
----------------------
E
I
K
V
--
A
A
P
N
M
A
-
Q
Q
-------------------
V
I
-----------
D
M
-----
A
I
---------
Q
I
H
G
G
G
G
L
S
N
D
F
P
L
--
A
---
A
A
W
V
N
A
-----
R
A
L
R
-------------
L
A
D
--
G
----------
P
D
E
V
H
-
R
G
-
V
V
A
R
I
E
L
---------
A
K
Y
----------
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
31.06
20%
-19
- C7 -
2QI9
-
BTUC_ECOLI
A:
[206-246]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
S
R
---
P
M
N
M
L
A
L
G
E
I
S
-
A
R
---
Q
L
-
G
L
P
L
W
F
W
R
N
V
-
L
V
A
A
T
------
G
W
---------------
M
V
G
V
S
V
A
L
----------------------
A
G
A
I
--
G
F
I
G
L
V
-
I
P
-------------------
H
I
-----------
L
R
-----
L
S
---------
G
L
T
D
H
R
V
L
L
P
G
C
A
L
--
A
---
G
A
S
A
L
L
-----
L
A
D
I
-------------
V
A
R
--
L
----------
A
L
A
A
A
-
E
L
-
P
I
G
V
V
T
A
---------
T
L
G
----------
A
P
V
-
F
I
W
L
L
L
K
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
29.05
21%
129
- C5 -
2KEG
-
?
A:
[1-32]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
--
S
R
K
N
G
I
-
G
Y
-------------------
A
I
-----------
G
Y
-----
A
F
---------
G
A
V
E
R
A
V
L
G
G
S
R
D
Y
--
N
---
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
22.18
28%
219
- C7 -
1Y6U
-
?
A:
[17-34]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
-
S
K
---
Y
F
-
R
I
G
E
N
K
L
R
R
L
-
A
E
E
N
K
------
N
A
---------------
N
W
L
I
M
N
G
N
----------------------
R
I
Q
I
--
K
R
K
Q
F
E
-
K
I
-------------------
I
D
-----------
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------