@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0759: (2015-12-02 )
MIEIAVLIIAIAFVVLVLGILFVLKKVSETIEETKQTIKVLTSDVNVTLYQTNEILAKANVLVDDVNGKVSTIDPLFVAIADLSESVSDLNLQARHIGQKASSATSSVTKAGSALAIGKAASKIFRKKGDKK
Atome Classification :
(20 SA)
-------....-.....10........20.....---...30........40..--......50-------.--.--.......60---.------....-....70-........-----.80---------.........90...--.....100.......110......---------.120......------.130---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------M
I
E
I
-
A
V
L
I
I
A
I
A
F
V
V
L
V
L
G
I
L
F
V
L
K
K
---
V
S
E
T
I
E
E
T
K
Q
T
I
K
V
L
TS--DV
N
V
T
L
Y
--------Q--T--N
E
I
L
A
KA
N
----
V
------
L
V
DD-VNGKV--ST
I
D
P
L
F
V
-----
A
I
----------
A
D
L
S
E
S
V
S
DL
N
L
Q
A
--
R
HIGQKASSA
T
S
S
V
TKAGS
A
L
A
I
G
---------
K
A
A
S
K
I
F
R
KK------GDKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
73.40
18%
-85
* C8 *
1D4O
1
A:
[5-181]
GT
H
T
E
I
N
L
D
N
A
-
I
D
M
I
R
E
A
N
S
I
I
I
T
P
G
Y
G
L
C
A
A
K
---
A
Q
Y
P
I
A
D
L
V
K
M
L
S
E
Q
G
K
--
K
V
R
F
G
I
H
PVAGRMPG
Q
--
L
--
N
V
L
L
A
E
A
G
----
V
PYDIVL
E
M
D
E
-
I
N
H
D
F
--
P
D
T
D
L
V
L
V
IGAND
T
V
----------
N
S
A
A
Q
E
D
P
N
S
I
I
A
G
--
M
P
V
L
E
V
W
K
S
K
Q
V
I
V
M
K
R
S
L
G
V
G
Y
A
---------
A
V
D
N
P
I
F
Y
K
P
NTAMLL
G
D
A
K
K
T
C
D
A
L
Q
A
K
V
R
E
S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
66.86
26%
-8
- C6 -
4C5J
1
?
A:
[83-168]
--------------------------------------------------------------------------
T
--
E
E
I
I
K
R
A
G
----
E
------
V
Y
E
A
-
S
N
A
Q
Y
--
F
V
V
D
P
V
M
V
-----
C
K
----------
G
E
-
D
E
V
L
N
P
G
N
T
E
A
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
N
L
F
E
A
G
Q
L
S
G
L
G
KLNS
I
E
D
M
K
K
A
A
T
I
I
F
D
K
G
------
A
Q
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.00
32%
-34
- C6 -
4XGU
-
PCH2_CAEEL
A:
[277-334]
---------------------------------------------------------
V
N
A
L
L
T
--------
Q
--
I
--
D
R
I
R
R
R
D
N
----
V
------
L
I
L
C
-
T
S
N
L
E
--
S
T
L
D
K
A
L
V
-----
D
R
----------
A
D
I
V
K
N
V
G
Q
P
S
D
F
A
--
R
Y
S
M
L
K
S
S
I
M
E
L
A
R
I
G
V
V
I
D
N
E
V
H
---------
T
D
Y
W
P
Q
D
I
C
D
------
T
K
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.73
26%
-3
- C6 -
4C5K
1
?
A:
[83-168]
--------------------------------------------------------------------------
T
--
E
E
I
I
K
R
A
G
----
E
------
V
Y
E
A
-
S
N
A
Q
Y
--
F
V
V
D
P
V
M
V
-----
C
K
-------------
D
E
V
L
N
P
G
N
T
E
A
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
N
L
F
E
A
G
Q
L
S
G
L
G
KLNS
I
E
D
M
K
K
A
A
T
I
I
F
D
K
G
------
A
Q
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
61.96
13%
-113
- C8 -
2Q3E
3
UGDH_HUMAN
A:
[2-467]
-------
M
F
E
I
K
K
I
C
C
I
G
A
G
Y
V
G
G
P
T
C
S
V
I
A
H
M
C
PE
I
R
V
T
V
V
D
V
N
E
S
R
I
N
A
W
N
S
--
P
-
T
L
P
I
Y
--------
E
--
P
G
L
K
E
V
V
E
S
C
R
GKNL
F
------
F
S
T
N
-
I
D
D
A
I
--
K
E
A
D
L
V
F
I
-----
S
V
N
T
P
TKTYGMG
K
G
R
A
A
D
L
K
Y
I
E
A
C
A
--
R
R
I
V
Q
N
S
N
G
Y
K
I
V
T
E
K
S
T
V
P
V
R
A
A
---------
E
S
I
R
R
I
F
D
A
N
------
T
K
P
N
L
N
L
Q
V
L
S
N
P
E
FLAEGT
A
I
K
D
L
K
NPD
R
V
L
I
G
G
D
ET
P
E
G
Q
R
A
V
Q
A
L
C
A
V
Y
E
H
WVPREK
I
L
T
T
N
T
W
S
S
E
L
S
K
L
A
A
N
A
F
L
A
Q
R
I
S
S
I
N
S
I
S
A
L
C
E
A
T
GAD
V
E
E
V
A
T
A
I
G
M
DQRIGNKFLKASV
G
F
G
G
SC
F
Q
K
D
V
L
N
L
V
Y
L
C
E
A
L
NL
P
E
V
A
R
Y
W
Q
Q
V
I
D
M
N
D
Y
Q
R
R
R
F
A
S
R
I
I
D
S
L
FNTVTD
K
K
I
A
I
L
G
FAFKKDTGDTRES
S
S
I
Y
I
S
K
Y
L
M
D
E
G
A
H
L
H
I
Y
D
PKVP
R
E
Q
I
V
V
D
L
SHDQVSRL
V
T
I
S
KD
P
Y
E
A
C
DGAH
A
V
V
I
C
T
EW
D
M
F
K
E
LD
Y
E
R
I
H
K
K
MLKP
A
F
I
F
D
GRRVLDGL
H
N
E
L
Q
T
I
GFQ
I
E
T
I
GKKV
5
PsiBlast_PDB
60.48
26%
1
- C6 -
4C5M
2
?
A:
[83-168]
--------------------------------------------------------------------------
T
--
E
E
I
I
K
R
A
G
----
E
------
V
Y
E
A
-
S
N
A
Q
Y
--
F
V
V
D
P
V
M
V
-----
C
K
--------------
E
V
L
N
P
G
N
T
E
A
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
N
L
F
E
A
G
Q
L
S
G
L
G
KLNS
I
E
D
M
K
K
A
A
T
I
I
F
D
K
G
------
A
Q
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
59.87
26%
-5
- C6 -
4C5N
1
?
A:
[83-168]
--------------------------------------------------------------------------
T
--
E
E
I
I
K
R
A
G
----
E
------
V
Y
E
A
-
S
N
A
Q
Y
--
F
V
V
D
P
V
M
------------------------
L
N
P
G
N
T
E
A
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
N
L
F
E
A
G
Q
L
S
G
L
G
KLNS
I
E
D
M
K
K
A
A
T
I
I
F
D
K
G
------
A
Q
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.28
26%
2
- C6 -
4C5L
3
?
A:
[83-168]
--------------------------------------------------------------------------
T
--
E
E
I
I
K
R
A
G
----
E
------
V
Y
E
A
-
S
N
A
Q
Y
--
F
V
V
D
P
V
M
V
-----
C
K
----------
G
E
-----
N
P
G
N
T
E
A
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
N
L
F
E
A
G
Q
L
S
G
L
G
KLNS
I
E
D
M
K
K
A
A
T
I
I
F
D
K
G
------
A
Q
H
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
57.34
17%
-65
- C1 -
2HJQ
-
YQBF_BACSU
A:
[1-111]
-------
M
F
T
A
-
K
L
I
K
---
G
K
T
Y
N
V
M
G
I
T
F
R
-
A
G
---
V
S
Q
T
V
P
--
K
K
L
Y
E
Y
L
N
E
--
N
P
Y
F
I
L
T
--------
Q
--
E
--
L
N
-----
N
----
Q
------
K
D
D
P
-
I
N
Y
T
E
--
S
E
L
K
G
M
------------------------
N
K
A
E
H
E
S
I
I
--
S
N
L
G
R
N
P
S
D
F
K
N
A
D
E
R
I
A
Y
I
L
K
Q
I
---------
D
N
K
G
E
L
E
H
H
H
------
H
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
53.39
27%
-26
- C6 -
2VSO
-
IF4F1_YEAST
E:
[34-88]
------------------------------------------
D
E
V
E
R
K
M
K
S
L
L
N
--
K
L
T
L
E
M
F
--------
D
AI
S
--
S
E
I
L
A
I
A
N
----
I
------
S
V
W
E
-
T
N
G
E
T
LK
A
V
I
E
Q
I
F
L
-----
K
A
----------
C
D
E
P
H
W
S
S
M
Y
A
Q
L
C
--
G
K
V
V
K
E
L
N
P
D
I
T
D
E
T
K
T
G
P
K
L
V
L
H
---------
Y
L
V
A
R
C
H
A
E
F
------
D
K
G
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
52.77
27%
-20
- C6 -
2VSX
-
IF4F1_YEAST
E:
[34-88]
------------------------------------------
D
E
V
E
R
K
M
K
S
L
L
N
--
K
L
T
L
E
M
F
--------
D
AI
S
--
S
E
I
L
A
I
A
N
----
I
------
S
V
W
E
-
T
N
G
E
T
LK
A
V
I
E
Q
I
F
L
-----
K
A
----------
C
D
E
P
H
W
S
S
M
Y
A
Q
L
C
--
G
K
V
V
K
E
L
N
P
D
I
T
D
E
T
K
T
G
P
K
L
V
L
H
---------
Y
L
V
A
R
C
H
A
E
F
------
D
K
G
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
50.89
25%
-130
- C6 -
3J2W
-
POLS_CHIK3
E:
[25-44]
-------------
G
L
I
V
A
V
A
A
L
I
L
I
V
V
L
C
V
S
F
S
R
---
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
47.33
40%
26
- C6 -
4B8B
1
NOT1_YEAST
A:
[180-219]
--------------------------------
R
K
---
V
S
E
T
I
P
N
T
K
Q
S
L
L
Y
L
L
S
I
A
S
L
N
L
E
L
F
--------
L
--
Q
--
R
E
E
L
S
D
G
P
----
M
------
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
46.47
16%
27
- C7 -
1VFI
-
VBP2_ASCSS
A:
[1-95]
----------------------------------------
I
S
E
F
A
P
V
D
C
K
G
Q
C
T
--
T
P
C
E
P
L
T
--------
A
--
C
--
K
E
K
C
A
E
S
C
-------------
E
T
-
S
A
D
K
K
--
T
C
R
R
N
C
K
K
-----
A
D
----------
C
E
P
Q
D
K
V
C
D
A
C
R
M
K
--
C
H
K
A
C
R
A
A
N
C
A
S
E
C
P
K
H
E
H
K
S
D
T
C
---------
R
A
C
M
K
T
N
C
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
44.86
15%
10
- C6 -
3N27
2
?
A:
[8-66]
-------------------------------
I
N
K
---
L
K
S
S
I
E
S
T
N
E
A
V
V
K
L
Q
E
--
T
A
E
K
T
V
Y
--------
V
--
L
--
T
---------------------
A
-
L
Q
D
Y
-------
G
I
--------------------
D
I
S
I
E
L
N
K
A
K
S
D
L
--
E
E
S
K
E
W
I
R
R
S
N
Q
K
L
D
S
I
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
43.38
24%
-26
- C6 -
1K39
1
ECI1_YEAST
A:
[82-142]
---------------------------------------
D
T
N
K
Y
P
S
E
T
S
K
W
V
S
N
--
F
V
A
R
N
V
Y
--------
V
--
T
--
D
A
F
I
K
H
S
K
----
V
------
L
I
C
C
-
L
N
G
P
A
--
I
G
L
S
A
A
L
V
-----
A
L
----------
C
D
I
V
Y
S
I
N
D
K
V
Y
L
L
--
Y
P
F
A
N
L
G
L
I
T
E
G
G
T
T
V
S
L
P
L
K
F
G
T
---------
N
T
T
Y
E
C
L
M
F
N
------
K
P
F
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
39.01
31%
-19
- C6 -
4UDU
1
ETXE_STAAU
C:
[111-161]
-----------------------------------------------------------
V
T
L
H
--------
D
--
N
--
N
R
L
T
E
E
K
K
----
V
------
P
I
N
L
W
I
D
G
K
Q
--
T
T
V
P
I
D
K
V
-----
K
T
----------
S
K
K
E
V
T
V
Q
E
L
D
L
Q
A
--
R
H
Y
L
H
G
K
F
G
L
Y
N
S
D
S
F
G
G
K
V
Q
R
G
L
---------
I
V
F
H
S
S
E
G
S
T
------
V
S
Y
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
38.55
14%
15
- C4 -
2KK4
-
Y2094_ARCFU
A:
[1-95]
-------------------------
Q
G
H
M
D
L
I
C
M
---
Y
V
F
K
G
E
E
S
F
G
E
S
I
D
V
Y
G
--
D
Y
L
I
V
K
V
--------
G
--
T
--
E
F
L
A
V
P
K
K
----
S
------
I
K
S
V
-
E
D
G
R
I
--
V
I
G
E
F
D
-----------------------------
E
E
E
A
--
R
E
L
G
R
K
W
L
E
E
K
S
K
P
V
T
L
E
E
L
K
S
Y
G
---------------
F
G
E
E
------
G
E
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
37.68
10%
-1
* C7 *
1WA8
-
B:
[601-695]
-------------------------------
M
T
E
---
Q
Q
W
N
F
A
G
I
E
A
A
A
S
A
I
Q
G
--
N
V
T
S
I
H
S
--------
L
--
L
--
D
E
G
K
Q
S
L
T
----
K
------
L
A
A
A
-
W
G
G
S
G
--
S
--
E
A
Y
Q
G
-----
V
Q
----------
Q
K
W
D
A
T
A
T
E
L
N
N
A
L
--
Q
N
L
A
R
T
I
S
E
A
G
Q
A
M
A
S
T
E
G
N
V
T
G
M
---------
F
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
37.68
13%
29
- C6 -
1T3J
-
MFN1_MOUSE
A:
[674-726]
---------------------------------------------
A
T
T
F
A
R
L
C
Q
--
Q
V
D
M
T
Q
K
--------
H
--
L
--
E
-----------
E
------
E
I
A
R
-
L
S
K
E
I
--
D
Q
L
E
K
M
Q
N
-----
N
S
----------
K
L
L
R
N
K
A
V
Q
L
E
S
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------