@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0106: (2016-04-19 )
MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTATLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPICWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVTVGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTPHTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPDQVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVLVCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHRNSGESR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------......-...10...--.....20..--.-------..-----.-..30------.....-...------40...--------....-------.-50---.........60-........------70--.----....----...80---.----.-----.-----.....90---.......--------..100-.-...------.....110....--...120----.........130.......140.......150.......160......----.170....---.-----.-----.180.......190--..---.-.....200---........210-----------........--220...--....230------.......240.......250......----.260--..-....-.---..270.......--..280.......290.......300.......310.......320.......330..-.....340.------.......350.......360.......370.......380.......390......--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------MRT
P
V
I
-
L
V
AGQD
H
T
--
D
E
V
T
G
A
L
L
R--R-------T
G
-----
T
-
V
V
V
E
------HRFD
G
-
H
V
V
------
R
R
M
T
A
--------
T
LSR-------G-
E
----
L
I
T
T
E
D
A
L
E
F
A
-
H
G
C
V
S
C
T
I
------
R
D
--
D
----
L
L
V
L
----
L
R
R
L
H
---R----R-----D-----NV
G
R
I
V
----
V
H
LAPWL--------EPQ---P-
I
C
W
------
A
I
D
H
V
R
V
C
V
GHG--YPDG------P
A
A
L
D
V
R
V
A
A
V
V
T
C
V
D
C
V
R
W
L
P
Q
S
LGEDELPDG
R
T
V
A
Q
V
T
VGQA
E
F
A
D
----
L
L
V
L
THP
E
---
P
-----
V
-----
A
V
A
V
L
R
R
LA
P
R
A
R---IT---G-G
V
D
R
V
E
-
L
---
A
L
A
HLDDNSR------------RGRTDTPH--T
P
L
LAG--LPPLAAD------G
E
V
A
I
V
E
FSARRPF
H
P
Q
R
L
H
A
A
V
D
L
L
----
L
D
----
G
V
-
V
RTR-G---
R
L
W
--LANRPD
Q
--
V
M
W
L
ESAGG
G
L
R
V
ASAG
K
W
L
A
A
M
A
AS
E
V
A
Y
V
D
L
E
R
R
L
F
A
D
L
M
W
V
YPFGDR
H
T
A
M
T
V
L
-
V
CGA
D
P
-
T
D
------
I
V
N
A
L
N
A
A
LLSDDEMA
S
P
Q
R
W
Q
S
YVDPFGDWHDD
P
C
H
EMPDAAGEFSAHRNSGESR--
21
HHSearch
71.62
16%
-115
- C2 -
1NIJ
-
YJIA_ECOLI
A:
[2-317]
--------------------------------------------------------------------------------------
N
P
I
A
V
T
-
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
E-
Q
HG-----
Y
K
-----
I
-
A
V
I
E
------
N
E
F
G
E
V
S
V
D
------
D
Q
L
I
G
--------
D
R
-------------------
A
T
Q
I
K
T
L
T
-
N
G
C
I
C
C
S
R
------
S
N
--
E
----
L
E
D
A
----
L
L
D
L
L
---
D
----
N
L
D
K
GN
I
-----
Q
F
D
R
L
V
----
I
E
C
T
G
M
A
--------
D
P
G
---
P
-
I
I
Q
------
T
F
F
S
H
E
------------------
V
L
C
Q
R
Y
L
L
D
G
V
I
A
L
V
D
A
V
H
A
D
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Q
M
N
Q
----------
F
T
I
A
Q
S
Q
V
G
Y
A
D
----
R
I
L
L
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K
T
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VA-
G
EA---
E
K
----
L
H
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L
A
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N
A
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A
P
---
V
Y
---
T
V
T
H
G
D
I
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L
G
LLF
N
T
N
G
F
M
L
E
E
N
------------
V
V
S
T
------
K
P
R
F
----
H
F
I
A
D
K
Q
------
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
L
L
E
S
A
D
----
K
L
-
L
R
Y
K
-
G
---
M
L
W
--
I
D
G
E
P
-
N
--
R
L
L
F
Q
G
V
Q
R
L
Y
S
A
D
W
D
R
P
W
G
D
--------------------------
E
K
P
H
S
T
M
V
F
I
-
G
I
Q
L
P
E
-
E
E
------
I
R
A
A
F
A
G
L
R
-------------------------------------------------
42
Fugue
70.96
16%
-110
- C2 -
1NIJ
-
YJIA_ECOLI
A:
[2-318]
--------------------------------------------------------------------------------------
N
P
I
A
V
T
-
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
--
E
-------
Q
H
GYK--
I
-
A
V
I
E
------
N
E
F
G
E
-
V
S
V
------
D
D
Q
L
I
--------
G
D
R
A
------------------
T
Q
I
K
T
L
T
-
N
G
C
I
C
C
S
R
------
S
N
--
E
----
L
E
D
A
----
L
L
D
L
L
---
D
----
N
-----
L
D
K
GNI
Q
F
D
R
L
V
----
I
E
C
T
G
M
A
--------
D
P
G
---
P
-
I
I
Q
------
T
F
F
S
------------
H
E
------
V
L
C
Q
R
Y
L
L
D
G
V
I
A
L
V
D
A
V
H
-
A
D
E
Q
M
N
Q
F
---------
T
I
A
Q
S
Q
V
G
Y
A
D
----
R
I
L
L
T
K
T
D
---
V
-----
A
GEA
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
---
V
Y
---
T
--
V
T
H
G
D
-
I
---
D
L
G
L
L
F
N
T
N
G
------------
F
M
L
E
E
N
V
V
--
S
T
K
P
R
F
--
H
F
I
A
D
K
Q
------
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
----
L
L
E
SAD
K
L
-
L
R
Y
K
-
G
---
M
L
W
--
I
D
G
E
P
N
R
--
L
L
F
Q
G
V
---------------------------
Q
R
L
Y
S
A
D
W
D
R
P
W
G
D
E
K
P
H
S
T
M
V
F
I
-
G
I
Q
L
P
E
-
E
E
------
I
R
A
A
F
A
----------------------------
G
L
R
K
--------------------
49
Fugue
60.78
20%
-76
- C3 -
4Q0C
-
BVGS_BORPE
A:
[33-545]
S
Q
E
L
T
LVGKA
A
V
P
D
V
EVALDGD
D
W
R
W
L
A
R
K
R
V
L
T
L
G
V
Y
A
PDIPPF
D
V
T
Y
GE
R
Y
E
G
L
T
A
D
Y
M
A
I
I
A
H
N
L
GMQ
A
K
V
L
R
Y
PT
R
E
Q
A
L
S
A
L
E
S
G
Q
I
D
L
I
G
T
V
N
G
T
--
D
G
R
Q
Q
S
L
R
L
--
S
-------
V
P
Y
A
A
D
H
P
-
V
I
V
M
------
P
I
G
A
R
-
H
V
P
ASNLAG
Q
R
L
A
V
DINYLP
K
E
T
L
A
R
A
YPQ
A
T
L
H
-
Y
----
F
P
S
S
E
Q
A
L
A
A
V
A
Y
G
Q
A
D
V
F
I
------
G
D
--
A
----
L
T
T
S
----
H
L
V
S
Q
---
S
----
Y
-----
F
-----
N
D
V
R
V
V
----
A
P
A
H
I
A
T
--------
G
G
E
---
S
-
F
G
V
RADN
T
R
L
L
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V
V
N
A
V
L
E
A
I
--
P
P
S
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------
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I
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L
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S
I
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L
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A
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W
M
A
D
H
P
V
V
K
V
A
V
L
N
-
L
F
A
P
----
F
T
L
F
R
T
D
E
---
Q
-----
F
G
G
I
--
S
A
A
V
L
Q
L
L
Q
L
R
T
G
L
D
F
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---
I
-
G
V
D
T
V
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-
E
---
L
I
A
K
L
R
S
G
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A
DMAG--------
A
L
F
V
N
S
A
R
--
E
S
F
L
S
F
--
S
R
P
Y
V
R
N
------
G
M
V
I
V
T
R
Q
D
P
D
A
P
V
D
A
D
H
L
D
G
R
T
V
A
L
----
V
R
----
N
----
S
A
-
A
---
I
P
L
--
L
Q
R
R
Y
P
Q
A
K
V
V
T
A
D
N
P
S
E
A
M
L
M
V
A
N
G
Q
A
D
A
V
V
Q
T
Q
I
S
A
S
Y
Y
V
N
R
Y
-
F
A
G
K
L
R
I
A
S
A
L
D
L
P
P
A
E
I
A
L
-
A
T
T
R
G
Q
-
T
E
------
L
M
S
I
L
N
K
A
L
Y
S
----
I
S
N
D
E
L
A
S
I
I
S
R
W
R
G
S
D
G
D
--------
P
R
T
W
Y
A
Y
R
N
E
I
Y
L
E
--
45
Fugue
58.01
17%
-54
- C1 -
4RDQ
9
?
A:
[1-366]
------------------------------------------------------------------------------------------------
T
V
T
Y
T
--
N
R
V
A
D
A
-----
R
-------
L
G
-----
T
F
S
Q
L
L
------
L
Q
W
K
G
-
S
I
Y
------
K
L
L
Y
S
--------
E
F
L
I
-------
F
-
I
----
S
L
Y
F
A
I
S
L
V
Y
R
-
L
------------------------------
I
L
S
E
S
---
Q
----
R
-----
L
-----
M
F
E
K
L
A
----
L
Y
C
N
S
Y
A
--------
E
L
I
---
P
-
V
S
F
------
V
L
G
F
Y
V
S
L
V
V
S
R
--
W
W
A
Q
Y
E
S
IPW
P
D
R
I
M
N
L
V
S
C
N
V
D
------------
G
E
D
E
Y
--
G
R
L
L
R
R
T
L
M
R
Y
S
N
L
C
S
----
V
L
I
L
---
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-----
S
T
A
V
Y
K
R
F
P
S
M
E
H
---
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---
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-
A
----------
G
L
M
T
P
E
E
H
K
K
------------
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--
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K
F
W
I
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C
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G
R
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R
D
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V
L
L
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----
R
S
----
Q
C
-
G
R
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Y
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G
---
Y
D
W
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I
P
L
V
Y
T
Q
--
V
V
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Y
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F
F
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A
C
L
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Q
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W
L
I
D
R
N
L
Q
V
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L
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A
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Q
D
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K
D
L
Y
W
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P
D
P
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P
P
Y
T
A
A
T
A
E
Y
K
R
P
S
F
L
G
S
T
F
D
I
S-
48
Fugue
57.84
21%
-15
- C2 -
4C88
-
?
A:
[0-337]
---------------------------------------------------------------------------------------
G
M
P
T
I
-----
N
S
I
Q
--
T
T
V
N
G
V
V
K
I
--
V
-------
K
P
FN---
N
-
D
I
A
G
------
E
Q
F
D
P
-
H
V
L
------
Q
T
L
T
A
--------
F
K
Q
P
-------
A
-------
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L
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N
D
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A
A
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R
-
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T
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----
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A
----
V
T
V
Q
S
---
R
----
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-----
T
A
L
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T
----
V
S
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-
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L
--------
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---------
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T
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G
G
A
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G
G
------
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N
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K
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A
I
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----
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---
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-----
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-----
T
V
A
------------------
G
-
D
S
A
G
A
N
-
V
---
I
M
A
A
T
N
L
N
Q
Q
------------
L
G
S
N
R
I
N
Q
--
Q
L
L
L
Y
-----
P
V
T
A
----------------------
P
N
A
D
H
A
G
P
L
W
D
----
L
A
----
A
F
P
I
I
D
S
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Q
---
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A
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--
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T
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H
D
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--
F
R
Q
L
D
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T
D
Y
Y
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P
E
N
F
D
S
H
S
P
L
I
S
------
P
L
H
Q
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N
F
----------
T
M
T
P
P
T
T
I
M
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V
G
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------
Q
A
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A
Y
A
Q
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L
A
A
A
D
T
A
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F
I
Q
Y
Q
G
L
N
H
A
F
A
P
L
V
D
Q
Y
-
W
Q
S
Q
D
V
A
Q
V
M
A
A
A
L
I
-------
47
Fugue
56.07
16%
-61
* C3 *
4BWZ
2
?
A:
[3-386]
------------------------------------------------------------------------------------------------
G
A
E
H
L
--
L
E
I
F
Y
L
L
L
A
--
A
-------
Q
V
-----
C
-
A
F
I
F
------
K
R
L
N
Q
P
V
V
I
------
G
E
V
L
A
--------
G
V
L
V
-------
G
-
P
ALLG
L
V
H
E
G
E
I
L
E
F
L
-
A
E
L
G
A
V
F
L
------
L
F
-------
M
V
G
L
----
E
T
R
L
K
---
D
----
I
-----
L
-----
A
V
G
K
E
A
----
F
L
V
A
V
L
G
--------
V
A
L
---
P
-
F
L
G
------
G
Y
L
Y
G
L
E
I
---
G
--
F
E
T
L
------
P
A
L
F
-
L
G
T
A
L
V
A
T
S
V
G
I
T
A
R
V
L
Q
E
L
G
V
L
S
R
P
Y
S
R
I
I
L
G
A
A
V
I
D
D
V
L
G
L
----
I
V
L
A
C
V
N
G
---
V
-----
A
-----
E
T
G
Q
V
E
V
G
A
I
T
R
L
---
I
V
---
L
-
S
V
V
F
V
G
-
L
---
A
V
F
L
S
T
L
I
A
R
------------
L
P
L
E
R
L
P
V
--
G
S
P
L
G
F
--
A
L
A
L
G
----------
V
G
M
A
A
L
A
A
S
I
G
L
A
P
I
V
G
A
F
L
G
G
M
L
----
L
S
----
E
V
-
R
E
K
Y
-
R
L
E
E
P
I
F
--
A
I
E
S
F
L
A
--
P
I
F
F
A
M
V
G
V
R
L
E
L
S
A
L
A
S
P
V
V
L
V
A
G
T
V
V
T
V
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
T
Q
G
--
V
R
S
A
L
T
V
-
G
C
G
M
A
P
-
R
G
------
E
V
G
L
I
V
A
A
L
G
L
K
A
G
A
V
N
E
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
P
F
A
L
K
P
L
I
A
W
T
E
R
E
R
A
A
K
E
----
43
Fugue
55.91
12%
-55
- C2 -
3EPH
6
MOD5_YEAST
A:
[1-409]
---------------------------------------------------------------------------------------
S
K
K
V
I
-
V
I
A
G
T
T
G
V
G
K
S
Q
L
S
I
Q
L
A
Q
--
K
-------
F
N
-----
G
-
E
V
I
N
SDSMQV
Y
K
D
I
P
-
I
I
T
------
N
K
H
P
L
--------
Q
E
R
E
-------
G
-
I
----
P
H
H
V
M
N
H
V
D
W
S
-
E
E
Y
Y
S
H
R
F
------
E
T
--
E
----
C
M
N
A
----
I
E
D
I
H
---
R
----
R
-----
G
-----
K
I
P
I
V
V
GGTH
Y
Y
L
Q
T
L
F
NKRVDTKS
S
E
R
---
K
-
L
T
R
------
K
Q
L
D
I
L
E
S
T
D
P
D
--
V
I
Y
N
------
T
L
V
K
C
D
P
D
I
A
T
K
Y
H
P
N
D
Y
R
R
V
Q
R
M
L
-
E
I
Y
Y
K
T
G
K
K
P
S
E
T
F
N
E
Q
K
I
T
L
K
FD
T
L
F
L
W
L
Y
S
K
P
---
E
-----
P
-----
L
F
Q
R
L
D
D
R
V
D
D
M
L
---
E
R
---
G
-
A
L
Q
E
I
K
-
Q
---
L
Y
E
Y
Y
S
Q
N
K
F
------------
T
P
E
Q
C
E
N
G
--
V
W
Q
V
I
G
--
F
K
E
F
L
P
W
LTV
K
L
E
D
C
I
E
R
M
K
T
R
T
R
Q
Y
A
K
R
Q
V
K
W
I
K
K
M
L
I
----
P
D
---------
I
K
-
G
---
D
I
Y
--
L
L
D
A
T
D
L
--
S
Q
W
D
T
N
A
S
Q
R
A
I
A
I
S
N
D
F
I
S
N
R
P
I
K
Q
E
R
A
P
K
A
L
E
E
L
L
S
K
G
E
T
T
M
K
K
L
D
D
W
T
H
Y
T
C
N
V
-
C
R
N
A
D
G
-
K
N
------
V
V
A
I
------------
G
E
K
Y
W
K
I
H
L
G
S
R
R
H
K
S
N
L
K
R
N
T
R
Q
A
D
F
E
K
W
K
I
----------
28
HHSearch
54.00
13%
-126
- C2 -
4HI0
2
UREG_HELPY
E:
[1-175]
----------------------------------------------------------------------------------------
M
V
K
I
-
G
V
C
G
P
V
G
S
GK
T
A
L
I
E
A
L
T
R
H-
M
SKD----
Y
D
-----
M
-
A
V
I
T
------
N
D
I
Y
T
-
K
E
D
------
A
E
F
M
C
--------
K
N
S
V
-------
M
-------
P
R
E
R
I
I
G
V
E
T
-
G
G
C
P
H
T
A
I
------
R
E
--
D
----
A
S
M
N
LEA-
V
E
E
M
H
---
G
R---
F
-----
P
-----
N
L
E
L
L
L
----
I
E
S
G
G
D
N
----------------
L
S
A
------
T
F
-------------------------
N
P
E
L
A
D
F
T
I
F
V
I
D
V
A
E
G
D
K
I
P
-------------
R
K
G
G
P
G
I
T
R
S
D
----
L
L
V
I
N
K
I
D
LA-
P
YVG--
A
DLKV-
M
E
R
D
S
K
K
M
R
G
E
K
P
---
F
I
---
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
54.00
11%
-101
- C2 -
2HF9
4
HYPB_METJA
A:
[37-202]
---------------------------------------------------------------------------------------
G
V
V
A
F
-
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
-
L
KDK----
Y
K
-----
I
-
A
C
I
A
------
G
D
V
I
A
-
K
F
D
------
A
E
R
M
E
--------
K
H
-------------------
G
A
K
V
V
P
L
N
-
T
G
K
E
C
H
L
D
------
A
H
--
L
----
V
G
H
A
----
L
E
D
L
N
--------
L
-----
D
-----
E
I
D
L
L
F
----
I
E
N
V
G
N
L
--------
I
C
P
---
A
----------
D
------------------------
F
--
D
L
G
T
H
K
R
I
V
V
I
S
T
T
E
G
D
D
T
I
-------------
E
K
H
P
G
I
M
K
T
A
D
----
L
I
V
I
N
K
I
D
LAD
A
VG---
A
D
I
K
K
-
M
E
N
D
A
K
R
I
N
P
D
A
E
---
V
V
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
53.76
12%
-132
- C2 -
3E70
3
?
C:
[128-279]
---------------------------------------------------------------------------------------
K
P
Y
V
I
-
M
F
V
G
F
N
G
S
GK
T
T
T
I
A
K
L
A
N
W-
L
KNHG---
F
S
-----
V
-
V
I
A
A
------
S
D
T
F
R
A
G
A
I
------
E
Q
L
E
E
--------
H
-----------------------
A
K
R
I
G
-
V
K
V
I
K
H
S
Y
------
G
A
--
D
PAAV
A
Y
D
A
----
I
Q
H
A
K
--------
A
-----
R
-----
G
I
D
V
V
L
----
I
D
T
A
G
R
S
--------
E
T
N
---
R
N
L
M
D
------
E
M
K
---------------------
K
I
A
R
V
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
----------
Q
A
R
Q
F
N
-
E
A
V
K
I
D
----
G
I
I
L
T
K
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
53.39
13%
-78
- C2 -
4TQG
1
?
A:
[1-319]
------------------------------------------------------------------------------------SQ
I
N
D
K
T
I
-
M
I
F
G
--
G
S
--
G
S
L
G
N
R
L
I
E
--
T
-------
Y
I
-----
N
--------------------------
N
N
I
I
V
--------
N
Y
S
R
-------
D
-
E
----
S
K
H
W
S
M
E
L
K
Y
K
-
S
D
K
L
K
N
I
I
------
G
D
IR
D
----
F
E
K
V
----
Q
Q
S
I
M
---
R
----
I
-----
N
-----
P
--
D
I
I
----
I
I
A
A
----------------------------
A
L
K
H
I
D
R
C
E
Y
E
------
I
------
N
E
C
L
D
T
N
I
K
G
L
Q
N
V
L
K
V
T
E
I
-----
N
R
S
N
L
S
N
L
K
A
V
C
F
V
S
T
D
K
A
--------------------------------------
C
S
P
V
N
S
---
Y
G
---
M
-
S
K
A
I
C
E
-
T
---
L
V
V
E
K
S
K
Y
I
K
----------------
D
I
K
Y
--
V
C
V
R
Y
G
N
V
L
N
F
T
L
T
H
------
T
S
M
T
R
F
I
M
T
---------
L
D
D
S
V
K
L
I
----
E
Y
----
A
I
-
I
N
G
N
S
G
---
E
I
V
--
I
P
K
L
N
-------------
S
M
Y
I
K
D
M
I
E
L
F
A
D
K
Y
P
I
V
I
T
G
L
R
S
G
E
R
M
Y
E
S
L
I
------
N
D
T
Q
S
M
K
T
V
-
P
K
G
D
---------------
Y
Y
H
I
L
P
T
Y
D
P
T
I
V
T
E
E
F
Y
E
Y
S
S
K
Q
N
I
L
S
K
Q
E
L
E
N
Y
L
N
Q
----------------
26
HHSearch
50.98
11%
-100
- C2 -
4LPS
12
HYPB_HELPY
A:
[45-212]
---------------------------------------------------------------------------------------
G
L
Y
V
L
-
N
F
M
S
S
P
G
S
G
K
T
T
M
L
E
N
L
A
D
F-
K
D------
F
K
-----
F
-
C
V
V
E
------
G
D
L
Q
T
-
N
R
D
------
A
D
R
L
R
--------
K
K
-------------------
G
V
S
A
H
Q
I
T
-
T
G
E
A
C
H
L
E
------
A
S
--
M
----
I
E
G
-----
A
F
D
L
L
---
K
D
E
GA
L
-----
E
-----
K
S
D
F
L
I
----
I
E
N
V
G
N
L
--------
V
C
P
---
S
----------
S
Y
--------------------------
N
L
G
A
A
M
N
I
V
L
L
S
V
P
E
G
D
D
K
V
L
-------------
K
Y
P
T
M
F
M
C
A
D
----
A
V
I
I
S
K
A
D
M--
V
EVFNF
R
V
S
Q
--
V
K
E
D
M
Q
K
L
K
P
E
A
P
---
I
F
---
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
50.48
13%
-104
- C2 -
2WSM
1
?
A:
[29-192]
---------------------------------------------------------------------------------------
G
T
V
A
V
-
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
-
I
GNE----
V
K
-----
I
-
G
A
M
L
------
G
D
V
V
S
-
K
A
D
------
Y
E
R
V
R
--------
R
F
-------------------
G
I
K
A
E
A
I
S
-
T
G
K
E
C
H
L
D
------
A
H
--
M
----
I
Y
H
R
----
L
K
K
----------
F
-----
S
-----
D
C
D
L
L
L
----
I
E
N
V
G
N
L
--------
I
---------
C
------
P
V
D
-
F
-----------------------
D
L
G
E
N
Y
R
V
V
M
V
S
V
T
E
G
D
D
V
V
-------------
E
K
H
P
E
I
F
R
V
A
D
----
L
I
V
I
N
K
V
A
L--
A
EAVG-
A
D
V
E
K
-
M
K
A
D
A
K
L
I
N
P
R
A
K
---
I
I
---
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
49.45
12%
-124
- C2 -
1J8M
-
SRP54_ACIAM
F:
[98-250]
----------------------------------------------------------------------------------------
P
Y
V
I
-
M
L
V
G
V
Q
G
T
GK
T
T
T
A
G
K
L
A
Y
F-
Y
KKKG---
F
K
-----
V
-
G
L
V
G
------
A
D
V
Y
R
P
A
A
L
------
E
Q
L
-
Q
--------
Q
L
----------------------
G
Q
Q
I
G
-
V
P
V
Y
G
E
P
G
------
E
K
--
D
----
V
V
G
I
AKRG
V
E
K
F
L
--------
S
-----
E
-----
K
M
E
I
I
I
----
V
D
T
A
G
R
H
--------
G
Y
G
EEA
A
-
L
L
E
------
E
M
K
N
---------------------
I
Y
E
A
I
K
P
D
E
V
T
L
V
I
D
A
S
I
G
Q
K
A
Y
D
----------
L
A
S
K
F
N
Q
-
A
S
K
I
G
----
T
I
I
I
T
K
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
47.17
12%
-93
- C2 -
2P67
-
ARGK_ECOLI
A:
[56-205]
----------------------------------------------------------------------------------------
T
L
R
L
-
G
V
T
G
T
P
G
A
G
K
S
T
F
L
E
A
F
G
M
L
-
L
I
R
E
G---
L
K
-----
V
-
A
V
I
A
------
V
D
P
S
---------------------------
N
-------
D
L
A
----
R
A
E
A
A
F
I
R
P
V
P
-
S
-----
G
-------
A
S
--
Q
----
R
A
R
E
----
L
M
L
L
C
---
E
----
A
-----
A
-----
G
Y
D
V
V
I
----
V
E
T
V
G
V
G
--------
Q
S
E
---
T
---
E
-------
V
-----------------------
A
---
R
M
V
D
C
F
I
S
L
Q
I
A
-------
Q
------------
G
I
K
K
G
L
M
E
V
A
D
----
L
I
V
I
N
K
D
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
47.12
13%
-105
- C2 -
1LS1
4
SRP54_THEAQ
A:
[98-254]
----------------------------------------------------------------------------------------
R
N
L
W
-
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
-
Y
K
G
K
G---
R
R
-----
P
-
L
L
V
A
------
A
D
T
Q
R
P
A
A
R
------
E
Q
L
R
L
--------
L
G
E
----------------
K
V
G
V
P
V
L
E
V
M
-
D
G
E
S
----------
P
E
--
S
----
I
R
R
R
----
V
E
E
K
A
---
R
----
L
-----
E
-----
A
R
D
L
I
L
----
V
D
T
A
G
R
L
--------
Q
I
D
E
--
P
-
L
M
G
------
E
L
A
R
---------------------
L
K
E
V
L
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
----------
A
R
A
F
D
-
E
K
V
G
V
T
----
G
L
V
L
T
K
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
46.94
11%
-95
- C2 -
4XC8
3
ICMF_CUPMC
A:
[228-394]
---------------------------------------------------------------------------------------
A
V
P
V
L
-
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
R
-
F
R
L
D
Q
DDA
L
S
-----
I
-
A
V
I
S
------
I
D
P
S
R
R
K
S
G
------
G
A
L
L
G
--------
D
--------------------
R
I
R
M
N
A
I
N
-
H
P
N
I
F
M
R
S
L
A
TREA
G
S
--
E
----
I
S
Q
A
----
L
P
D
V
I
A
A
C
K
----
A
-----
A
-----
R
F
D
L
V
I
----
V
E
T
S
G
I
G
--------
Q
G
D
---
A
-
A
I
--------
V
---------------------------
P
H
V
D
L
S
L
Y
V
M
T
P
E
F
G
A
A
S
Q
-------------
L
E
K
I
D
M
L
D
F
A
D
----
F
V
A
I
N
K
F
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
46.38
13%
-111
- C2 -
2FFH
2
SRP54_THEAQ
A:
[98-259]
----------------------------------------------------------------------------------------
R
N
L
W
-
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G----
R
R
-----
P
-
L
L
V
A
------
A
D
T
Q
R
P
A
A
R
------
E
Q
L
R
L
--------
L
G
E
----------------
K
V
G
V
P
V
L
E
V
M
-
D
G
E
--
S
--------
P
E
--
S
----
I
R
R
R
----
V
E
E
K
A
---
R
----
L
-----
E
-----
A
R
D
L
I
L
----
V
D
T
A
G
R
L
--------
Q
I
D
---
E
P
L
M
G
------
E
L
A
R
---------------------
L
K
E
V
L
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
----------
V
A
R
A
F
D
E
K
V
-
G
V
T
----
G
L
V
L
T
K
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
45.68
11%
-102
* C2 *
3KL4
-
SRP54_SULSO
A:
[97-268]
----------------------------------------------------------------------------------------
P
F
I
I
-
M
L
V
G
V
Q
G
S
G
K
T
T
T
A
G
K
L
A
Y
F
-
Y
K
K
R
G---
Y
K
-----
V
-
G
L
V
A
------
A
D
V
Y
R
P
A
A
Y
------
D
Q
L
L
Q
--------
L
G
N
----------------
Q
I
G
V
Q
V
Y
G
E
P
-
N
N
Q
N
P
I
E
I
------
A
---------
K
K
G
----
V
D
I
F
V
--------
K
-----
N
-----
K
M
D
I
I
I
----
V
D
T
A
G
R
H
--------
G
Y
G
EET
K
-
L
L
E
------
E
M
K
E
---------------------
M
Y
D
V
L
K
P
D
D
V
I
L
V
I
D
A
S
I
G
Q
K
A
Y
D
----------
L
A
S
R
F
-
H
Q
A
S
P
I
G
----
S
V
I
I
T
K
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
44.49
12%
-38
- C2 -
3C48
3
MSHA_CORGL
A:
[19-438]
----------------------------------------------------------------------------------------
S
H
M
R
-
V
A
M
I
S
M
H
T
--
S
P
L
Q
Q
G
M
N
V
--
Y
-------
I
L
-----
S
-
T
A
T
E
------
L
A
K
Q
G
-
I
E
V
------
D
I
Y
T
R
--------
A
T
R
P
-------
S
-
Q
----
G
E
I
V
R
V
A
-----
E
N
L
R
V
I
N
I
------
A
A
--
G
----
P
Y
E
G
----
L
S
K
E
E
---
L
----
P
-----
T
-----
Q
L
A
A
F
T
----
G
G
M
L
S
F
T
--------
R
R
E
---
K
------------
V
T
Y
D
L
I
H
S
H
Y
--
W
L
S
G
------
Q
V
G
W
L
L
R
D
L
W
R
I
P
L
I
H
T
A
H
T
L
A
A
V
K
N
S
Y
D
T
P
E
S
E
A
R
R
I
C
E
Q
Q
L
V
D
N
A
D
----
V
L
A
V
N
T
Q
E
---
E
-----
M
-----
Q
D
L
M
H
H
Y
D
A
D
P
D
R
---
I
S
V
V
S
P
-
G
A
D
V
E
L
-
Y
---
S
P
G
T
E
R
S
R
R
E
L
GIPLH
T
K
V
V
A
F
V
G
R
L
Q
P
F
K
G
P
Q
V
L
I
K
A
--
V
A
A
L
F
D
R
------
D
P
D
R
N
L
R
V
I
I
C
G
G
P
S
D
T
Y
R
H
M
A
E
E
L
G
----
V
E
----
K
R
-
I
R
F
L
-
D
---
P
R
P
--
P
S
E
L
V
A
V
--
Y
R
A
A
D
I
V
A
V
P
S
F
N
E
S
F
G
L
V
A
M
E
A
Q
A
S
G
T
P
V
I
A
A
R
V
G
G
L
P
I
A
V
A
E
G
E
T
G
-------
L
L
-
V
D
G
H
S
P
-
H
A
------
W
A
D
A
L
A
T
L
L
D
D
D
E
T
R
I
R
M
G
E
D
A
V
E
H
A
R
T
F
S
W
A
A
T
A
A
Q
L
S
S
L
Y
N
D
A
I
A
N
E
N
V
D
G
E
T
H
HG