@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1627: (2016-03-26 )
MTKTLTNKLAEKEHAAVVTYIMGGDGGLDNLEEQLLFLEKSGVSAIEIGIPFSDPVADGPIIQLAGLRALKEQVSLEAILNKLAMSKVQIPLIIMSYINPIFHLGIPKFVELVQKTPVKGLIIPDLPYEHQKLITPELQGTDIALIPLVSLTSPKERLEEIAKQAEGFIYAVTVNGTTGVRSEFDAHIDSHLAYLKSISPVPVLAGFGVSSIEHVEKFAHVCDGVIIGSKVVQMLHEEKTAELGAFLQKAAEVRIKN
Atome Classification :
(21 SA)
--.........10---........20...----.....30........40........50........60........70......---..80---..--....---.--.90........100.......110.......120.......130.......140.......150.......160.......170.......180...-.-...190.......200.......210..-.....-220........230....------.-..------240.......250.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MT
K
T
L
T
N
K
L
AE---KEH
A
A
V
V
T
Y
I
MGG----DGG
L
D
N
L
E
E
Q
L
L
F
L
EKSG
V
S
A
I
E
IGIPFSDPVADGP
I
I
Q
L
A
G
L
R
A
L
K
E
Q
V
S
L
E
---
A
I
L
N
---
K
L
--
A
M
SK---V--
Q
I
P
L
I
I
M
S
Y
I
N
P
I
F
HLG
I
P
K
F
V
E
L
V
Q
KTPVK
G
L
IIPDLPYEHQKLITPELQGT
D
I
A
L
I
P
L
VSLT
S
P
K
E
R
L
E
E
I
A
K
QAEG
F
I
Y
A
V
T
VNGTTGV
R
S
E
F
D
-
A
-
H
I
D
S
H
L
A
Y
L
K
SISPV
P
V
L
AGFGV
S
S
I
E
H
-
V
E
K
F
A
-
H
V-CDGV
I
I
G
S
K
V
V
Q
M
L
H
------
E
-
E
K
------
T
A
E
L
G
A
F
L
Q
K
A
A
E
VRIKN
2
PsiBlast_PDB
95.92
34%
-154
- C1 -
2EKC
-
TRPA_AQUAE
A:
[9-258]
--------
T
E
L
K
E
---
K
R
E
K
A
L
V
S
Y
L
M
V
G
----
Y
P
D
Y
E
T
S
L
K
A
F
K
E
V
L
K
N
G
T
D
I
L
E
I
G
F
P
F
S
D
P
V
A
D
G
P
T
I
Q
V
A
H
E
V
A
L
K
N
G
I
R
F
E
---
D
V
L
E
L
S
E
T
L
--
R
K
E
F
---
P
--
D
I
P
F
L
L
M
T
Y
Y
N
P
I
F
R
I
G
L
E
K
F
C
R
L
S
R
E
K
G
I
D
G
F
I
V
P
D
L
P
P
E
E
A
E
E
L
K
A
V
M
K
K
Y
V
L
S
F
V
P
L
G
A
P
T
S
T
R
K
R
I
K
L
I
C
E
A
A
D
E
M
T
Y
F
V
S
V
T
G
---------Y
E
-
R
I
K
K
K
V
E
E
Y
R
E
L
C
D
K
P
V
V
V
G
F
G
V
S
K
K
E
H
-
A
R
E
I
G
-
S
F
-
A
D
G
V
V
V
G
S
A
L
V
K
L
A
G
------
Q
-
K
K
------
I
E
D
L
G
N
L
V
K
E
L
K
E
-----
22
HHSearch
94.26
34%
-147
- C1 -
2EKC
-
TRPA_AQUAE
A:
[7-260]
------
K
F
T
E
L
K
E
---
K
R
E
K
A
L
V
S
Y
L
M
V
G
----
Y
P
D
Y
E
T
S
L
K
A
F
K
E
V
L
K
N
G
T
D
I
L
E
I
G
F
P
F
S
D
P
V
A
D
G
P
T
I
Q
V
A
H
E
V
A
L
K
N
G
I
R
F
E
---
D
V
L
E
---
L
S
--
E
T
L
R
K
E
F
P
--
D
I
P
F
L
L
M
T
Y
Y
N
P
I
F
R
I
G
L
E
K
F
C
R
L
S
R
E
K
G
I
D
G
F
I
V
P
D
L
P
P
E
E
A
E
E
L
K
A
V
M
K
K
Y
V
L
S
F
V
P
L
G
A
P
T
S
T
R
K
R
I
K
L
I
C
E
A
A
D
E
M
T
Y
F
V
S
V
T
G
----------
Y
E
R
I
K
K
K
V
E
E
Y
R
E
L
C
D
K
P
V
V
V
G
F
G
V
S
K
K
E
H
-
A
R
E
I
G
-
S
F
-
A
D
G
V
V
V
G
S
A
L
V
K
L
A
G
------
Q
-
K
K
------
I
E
D
L
G
N
L
V
K
E
L
K
E
G
L
---
27
HHSearch
90.87
35%
-133
* C1 *
1RD5
2
TRPA_MAIZE
A:
[8-261]
------
T
M
A
A
L
M
A
---
K
G
K
T
A
F
I
P
Y
I
T
A
G
----
D
P
D
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
---
A
V
L
E
---
M
L
--
R
E
V
T
PE-
L
--
S
C
P
V
V
L
L
S
Y
Y
K
P
I
M
----
F
R
S
L
A
K
M
K
E
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
-
P
-
R
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
-
V
K
Q
I
A
Q
W
G
-
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
------
E
-
A
A
S
P
K
Q
G
-
L
R
R
L
E
E
Y
A
R
G
M
K
N
A
L
---
1
PsiBlast_PDB
89.54
36%
-135
- C1 -
1RD5
2
TRPA_MAIZE
A:
[2-246]
---
S
R
P
V
S
D
T
M
A
A
L
M
A
K
G
K
T
A
F
I
P
Y
I
T
A
G
----
D
P
D
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
---
A
V
L
E
---
M
L
R
E
V
T
P
E
---
L
--
S
C
P
V
V
L
L
S
Y
Y
K
P
I
M
F
R
S
L
A
K
M
K
E
----
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
-
P
-
R
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
-
V
K
Q
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
------
E
-
A
A
------
S
P
K
Q
G
-------------
8
PsiBlast_PDB
88.52
34%
-127
- C1 -
2DZP
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
N
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
3
PsiBlast_PDB
88.15
36%
-132
- C1 -
1TJR
1
TRPA_MAIZE
A:
[11-245]
----------
L
M
A
---
K
G
K
T
A
F
I
P
Y
I
T
A
G
----
D
P
D
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
---
A
V
L
E
---
M
L
R
E
V
T
P
E
---
L
--
S
C
P
V
V
L
L
S
Y
Y
K
P
I
M
S
R
S
L
A
E
M
K
E
----
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
-
P
-
R
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
-
V
K
Q
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
------
E
-
A
A
------
S
P
K
Q
G
-------------
44
Fugue
86.36
27%
-139
- C1 -
2TYS
-
TRPA_SALTY
A:
[1-268]
M
E
R
Y
E
N
L
F
A
Q
L
N
D
---
R
R
E
G
A
F
V
P
F
V
T
L
G
----
D
P
G
I
E
Q
S
L
K
I
I
D
T
L
I
D
A
G
A
D
A
L
E
L
G
V
P
F
S
D
P
L
A
D
G
P
T
I
Q
N
A
N
L
R
A
F
A
A
G
V
T
P
A
Q
C
F
E
M
L
A
---
L
I
--
R
E
K
H
---
P
--
T
I
P
I
G
L
L
M
Y
A
N
L
V
F
N
N
G
I
D
A
F
Y
A
R
C
E
Q
V
G
V
D
S
V
L
V
A
D
V
P
V
E
E
S
A
P
F
R
Q
A
A
L
R
H
N
I
A
P
I
F
I
C
P
P
N
A
D
D
D
L
L
R
Q
V
A
S
Y
G
R
G
Y
T
Y
L
L
S
---------------
P
L
H
H
L
I
E
K
L
K
E
Y
H
A
A
P
A
L
Q
G
F
G
I
S
S
P
E
Q
-
V
S
A
A
V
-
R
A
G
A
A
G
A
I
S
G
S
A
I
V
K
I
I
E
K
N
L
AS
P
K
-
Q
M
------
L
A
E
L
R
S
F
V
S
A
M
K
A
A
S
R
A
-
14
PsiBlast_PDB
85.92
34%
-129
- C1 -
2DZV
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
A
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
13
PsiBlast_PDB
85.33
34%
-129
- C1 -
2DZT
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
A
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
21
PsiBlast_CBE
85.28
36%
-135
- C1 -
1RD5
2
TRPA_MAIZE
B:
[2-246]
---
S
R
P
V
S
D
T
M
A
A
L
M
A
K
G
K
T
A
F
I
P
Y
I
T
A
G
----
D
P
D
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
--
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
---
A
V
L
E
---
M
L
R
E
V
T
P
E
---
L
--
S
C
P
V
V
L
L
S
Y
Y
K
P
I
M
F
R
S
L
A
K
M
K
E
----
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
------------
P
-
R
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
-
V
K
Q
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
------
E
-
A
A
------
S
P
K
Q
G
-------------
26
HHSearch
84.98
28%
-131
- C1 -
3NAV
1
TRPA_VIBCH
A:
[17-269]
----------------
A
Q
Q
G
A
F
V
P
F
V
T
I
G
----
D
P
N
P
E
Q
S
L
A
I
M
Q
T
L
I
D
A
G
A
D
A
L
E
L
G
M
P
F
S
D
P
L
A
D
G
P
T
I
Q
G
A
N
L
R
A
L
A
A
K
T
T
P
D
---
I
C
F
E
---
L
I
--
A
Q
I
R
A
R
N
P
--
E
T
P
I
G
L
L
M
Y
A
N
L
V
Y
A
R
G
I
D
D
F
Y
Q
R
C
Q
K
A
G
V
D
S
V
L
I
A
D
V
P
T
N
E
S
Q
P
F
V
A
A
A
E
K
F
G
I
Q
P
I
F
I
A
P
P
T
A
S
D
E
T
L
R
A
V
A
Q
L
G
K
G
Y
T
Y
L
L
S
R
A
--------
A
N
-
M
-
P
V
H
A
L
L
E
R
L
Q
Q
F
D
A
P
P
A
L
L
G
F
G
I
S
E
P
A
Q
-
V
K
Q
A
I
E
A
G
-
A
A
G
A
I
S
G
S
A
V
V
K
I
I
E
------
T
-
H
L
DN
P
A
K
Q
L
T
E
L
A
N
F
T
Q
A
M
K
K
A
T
---
43
Fugue
84.85
32%
-136
- C1 -
1GEQ
-
TRPA_PYRFU
A:
[1-248]
------
M
F
K
---------
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
-
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
---
I
V
--
K
E
F
R
---
R
H
S
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
-------
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
-
V
V
S
L
L
-
K
E
G
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
------
E
K--------
G
R
E
A
T
E
F
L
K
K
K
V
E
E
L
L
G
I
23
HHSearch
84.80
28%
-132
- C1 -
3VND
5
?
A:
[10-266]
--------
A
A
L
K
A
---
Q
D
K
G
A
F
V
P
F
V
T
I
G
----
D
P
S
P
E
L
S
L
K
I
I
Q
T
L
V
D
N
G
A
D
A
L
E
L
G
F
P
F
S
D
P
L
A
D
G
P
V
I
Q
G
A
N
L
R
S
L
A
A
G
T
T
S
S
---
D
C
F
D
---
I
I
--
T
K
V
R
A
Q
H
P
--
D
M
P
I
G
L
L
L
Y
A
N
L
V
F
A
N
G
I
D
E
F
Y
T
K
A
Q
A
A
G
V
D
S
V
L
I
A
D
V
P
V
E
E
S
A
P
F
S
K
A
A
K
A
H
G
I
A
P
I
F
I
A
P
P
N
A
D
A
D
T
L
K
M
V
S
E
Q
G
E
G
Y
T
Y
L
L
S
R
A
G
V
T
----------
P
I
E
N
I
L
T
Q
L
A
E
F
N
A
P
P
P
L
L
G
F
G
I
A
E
P
E
Q
-
V
R
A
A
I
K
A
G
-
A
A
G
A
I
S
G
S
A
V
V
K
I
I
E
------
A
-
H
Q
HD
E
A
T
L
L
A
K
L
A
E
F
T
T
A
M
K
A
A
----
9
PsiBlast_PDB
84.76
34%
-125
- C1 -
2DZU
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
N
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
7
PsiBlast_PDB
84.60
34%
-125
- C1 -
2DZS
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
A
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
10
PsiBlast_PDB
83.46
34%
-124
- C1 -
2DZW
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
12
PsiBlast_PDB
83.35
34%
-129
- C1 -
1WDW
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
------
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
5
PsiBlast_PDB
82.73
34%
-126
- C1 -
2DZX
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
A
A
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
11
PsiBlast_PDB
82.36
34%
-130
- C1 -
1GEQ
-
TRPA_PYRFU
A:
[3-243]
-----------------
K
D
G
S
L
I
P
Y
L
T
A
G
----
D
P
D
K
Q
S
T
L
N
F
L
L
A
L
D
E
Y
A
-
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
---
E
A
F
W
I
V
-
K
E
--
F
R
R
H
---
S
--
S
T
P
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
-------
E
I
P
-
K
-
T
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
G
--------
E
K
------
G
R
E
A
T
E
F
L
K
K
K
V
E
-----
15
PsiBlast_PDB
80.40
32%
-157
- C1 -
1UJP
1
TRPA_THET2
A:
[15-253]
------------------
R
A
A
L
I
P
Y
L
T
A
G
FPS
R
E
G
F
L
Q
A
V
E
E
V
L
P
Y
A
D
-----
L
L
E
I
G
L
P
Y
S
D
----
G
P
V
I
Q
R
A
S
E
L
A
L
R
K
G
M
S
V
Q
---
G
A
L
E
L
V
-
R
E
--
V
R
A
L
---
T
--
E
K
P
L
F
L
M
T
Y
L
N
P
V
L
A
W
G
P
E
R
F
F
G
L
F
K
Q
A
G
A
T
G
V
I
L
P
D
L
P
P
D
E
D
P
G
L
V
R
L
A
Q
E
I
G
L
E
T
V
F
L
L
A
P
T
S
T
D
A
R
I
A
T
V
V
R
H
A
T
G
F
V
Y
A
V
S
V
--------------
E
V
K
D
L
V
R
R
I
K
A
R
T
A
L
P
V
A
V
G
F
G
V
S
G
-
K
A
-
T
A
A
Q
A
-
A
V
-
A
D
G
V
V
V
G
S
A
L
V
R
A
L
E
------
E
-
G
R
------
S
-----------------
16
PsiBlast_PDB
78.38
32%
-152
- C1 -
1WXJ
5
TRPA_THET2
A:
[15-241]
------------------
R
A
A
L
I
P
Y
L
T
A
G
FPS
R
E
G
F
L
Q
A
V
E
E
V
L
P
Y
A
D
-----
L
L
E
I
G
L
P
Y
S
-----
G
P
V
I
Q
R
A
S
E
L
A
L
R
K
G
M
S
V
Q
---
G
A
L
E
L
V
-
R
E
--
V
R
A
L
---
T
--
E
K
P
L
F
L
M
T
Y
L
N
P
V
L
A
W
G
P
E
R
F
F
G
L
F
K
Q
A
G
A
T
G
V
I
L
P
D
L
P
P
D
E
D
P
G
L
V
R
L
A
Q
E
I
G
L
E
T
V
F
L
L
A
P
T
S
T
D
A
R
I
A
T
V
V
R
H
A
T
G
F
V
Y
A
V
S
---------------
E
V
K
D
L
V
R
R
I
K
A
R
T
A
L
P
V
A
V
G
F
G
V
S
G
-
K
A
-
T
A
A
Q
A
-
A
V
-
A
D
G
V
V
V
G
S
A
L
V
R
A
L
E
------
E
-
G
R
------
S
-----------------