@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0191: (2016-03-13 )
MRRKRKWLIVICVLLVLITISQILKHFNYGTESKEAYNTYTVEKERQLDLQGKAYPREVKTYYKNNQVGTYLGVQVADGQTVKKGDMLINYKINSNKRQQLVDKINDTQHIITEVYLNITKGLNNREIQKKLIEYKQTLYEAQQQLYQYDSQNRDSMYASFDGKIMIKNIDNDSDNQPILYLISKESHIKTSVTEFDLNKVKKGDKVNLSITSTGKTGAGIIKQISELPISYEENLSLHENDALHLPESNNDGELANSKSISASPIFKSNNNSELSKYGVIIDDLSLPIRAGYSLEIKVPLNAIKIPKSVLTKGNNVFIVNKNSIVEKRNIRIKRINGDIIVEKGLKPGDKLIKQPKSTMNDGDKVEISS
Atome Classification :
(20 SA)
.........10........20..-......30........40...---.....50......----..60........70.-------...-..-..80........90........--100....--...110------...---.....120.....-----------...130.-------...-------...140.......150----------.-..--.-...--160...---....170----.---..-..---.--.180.-..-.-...190.......200.----..---------....210.-.-.....220.......230.......240.......250.......260........270.......280.--......-290.......300---.----......310---.---.---.....320..----....-.330....-.-..--340....----...350.....-.---.360.-......370----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRRK
R
K
W
L
I
V
I
C
V
L
L
V
L
I
T
I
S
Q
I
-
L
K
HFNYGTESKEAYN
T
Y
TVEK---
E
R
QLDLQGKAY
P
R
----
E
V
K
T
Y
YKNNQ
V
G
T
Y
L
-------
G
V
Q
-VA-DG
Q
T
VKKG
D
M
L
I
N
Y
K
IN
S
N
K
R
Q
--
Q
L
V
D
K
IN--
D
T
Q
H
I
-------
I
T
E
---
V
Y
L
N
I
TK-GLN
N
R
-----------
E
I
Q
K
K
L
I
-------
E
Y
K
-------
Q
T
L
Y
E
A
Q
Q
Q
L
Y
Q
YDSQ----------N-RD--
S
-
M
Y
A--SFD
G
K
I
---
M
I
K
NIDN----D---SD-NQ---
P
--
I
L
Y
L
I-SK-E-SHIKTS
V
T
E
F
D
L
N
KVKK----G
D
---------
K
V
N
L
S
I
TS-T-GKT
G
A
G
I
I
K
Q
I
S
ELPISYEENLSLHEND
A
L
HLPESNNDGELANSKSI-SAS
P
I
FKSNNN
S
E
L
SKY
G
V
I
I
D--DLSL
P
I
-RAG
Y
S
L
E
I
K
V
PLN---A----IKI
P
K
S
V
LT---K---G---N
N
V
F
I
VNKNS----
I
V
E
K-RN
I
R
I
K
RI-N-G
D
--
I
I
V
EKGL----KP
G
D
K
L
I
KQ
P
K
-S---TMNDG-D
K
V
EISS------------
8
HHSearch
81.01
14%
-38
- C5 -
3LNN
1
?
A:
[27-350]
----------------------------------
R
R
T
L
A
V
A
P
A
T
R
E
T
V
A
A
P
F
N
L
P
A
M
I
E
A
D
PA--
K
L
V
K
V
L
-
P
P
L
A
G
R
I
V
-------
S
L
N
-
K
Q
-
L
G
D
E
V
K
A
G
D
V
L
F
T
I
D
S
A
D
L
A
Q
A
----
N
S
D
A
A
--
K
A
R
A
A
-------
M
T
M
---
A
R
R
N
L
D
R
-
Q
R
E
L
D
K
SE
I
-------
A
A
K
R
D
F
E
Q
A
Q
S
D
Y
D
Q
A
A
-------
S
E
S
Q
R
A
D
A
R
L
A
Q
L
G
A
K
G
GGTLQAGGG
H
-
I
L
--
A
-
V
R
S
--
P
I
N
G
R
V
---
V
D
L
N
A
A
T
G
A
Y
-
W
---
N
D
T
T
A
---
S
--
L
M
T
V
A
-
D
L
S
H
-
V
F
V
T
A
N
A
Q
E
K
D
L
G
H
V
Y
V
----
G
Q
---------
S
A
T
V
K
F
D
A
-
Y
-
D
D
P
Q
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
-------------------------------------------
T
R
T
T
K
V
R
M
V
F
D
N
P
D
G
R
L
-
R
P
G
M
F
A
Q
A
T
F
L
S
Q
P
H
E
G
----
I
V
V
P
M
S
A
I
V
---
Q
---
S
GF
Y
T
R
A
F
V
E
V
A
P
W
----
Q
F
E
P
-
R
V
I
K
L
G
A
Q
-
I
G
D
R
--
M
E
V
K
S
G
L
----
S
A
G
D
R
V
V
V
K
E
G
-
V
---
L
L
N
D
---------------------
2
PsiBlast_PDB
72.15
21%
-4
- C5 -
4L8J
5
?
A:
[43-325]
----------------------------------------------------------------------------
G
Q
I
I
-------
N
L
P
-
V
V
-
E
G
Q
R
V
K
K
G
Q
L
I
A
A
I
D
P
R
D
I
S
L
Q
--
Y
A
A
D
K
A
A
---
Y
E
T
A
-------
A
A
Q
---
V
E
R
N
-
K
R
-
L
L
G
R
Q
-----------
A
I
S
L
Q
E
Y
-------
E
I
S
-------
V
A
N
Y
Q
K
A
K
S
A
Y
E
L
S
T
N
----------
N
M
R
D
--
T
K
L
L
A
--
P
F
D
G
S
I
ETR
L
V
E
N
Y
Q
R
----
V
---
N
S
-
G
E
---
G
--
I
V
R
L
V
N
T
R
-
K
-
L
R
I
K
F
T
V
P
D
D
Y
L
Y
L
L
R
A
----
K
D
---------
A
---
T
F
K
V
-
E
-
F
D
T
Y
K
G
T
V
-----
F
N
A
R
L
E
E
Y
L
D
I
-
S
T
D
G
T
G
I
P
V
T
I
I
I
D
D
A
A
F
D
R
T
I
Y
D
V
K
P
G
F
T
C
N
I
R
--------
L
A
S
--
D
I
A
P
F
I
-
E
E
K
L
M
---
N
V
P
L
S
---
A
----
V
F
G
D
S
E
--
N
---
K
---
N
---
T
Y
V
W
I
V
K
D
N
K
-----
V
N
R
-
R
E
V
T
V
Y
S
P
-
T
-
G
E
A
N
L
L
I
S
K
G
L
----
K
P
G
E
T
V
V
T
A
G
V
-
Y
---
Q
L
V
E
G
-
Q
R
I
K
---------------
9
HHSearch
70.21
18%
-40
- C5 -
3FPP
-
MACA_ECOLI
A:
[43-308]
--------------------------------------------
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
----
R
K
V
D
V
G
-
A
Q
V
S
G
Q
L
K
-------
T
L
S
-
V
A
-
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
--
E
L
R
A
Q
R
Q
Q
A
E
A
E
L
K
L
---
A
R
V
T
Y
S
R
-
Q
Q
R
L
A
QTQAVSQ
Q
D
L
D
N
A
A
T
E
M
A
-------
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
---------
D
-
Y
T
--
R
-
I
V
A
--
P
M
A
G
E
V
---
T
Q
I
T
T
L
Q
G
Q
T
-
V
---
I
A
-
A
Q
Q
A
P
N
--
I
L
T
L
A
-
D
M
S
A
-
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
-----------------------------------------
A
I
F
Y
Y
A
R
F
E
V
P
N
P
N
G
L
L
-
R
L
D
M
T
A
Q
V
H
I
Q
L
T
---
D
V
K
N
V
L
T
--------------------------------------------------------------------------------------------------------
30
Fugue
64.65
16%
-10
- C5 -
4KKU
-
?
A:
[23-296]
------------------------------------------------------------------------------
Y
R
-------
F
P
V
-
I
A
M
K
V
K
K
G
I
L
S
D
Y
L
S
L
N
G
D
V
D
T
K
V
K
--
A
D
I
F
P
D
A
----
V
G
K
-------
I
T
S
---
L
R
I
K
L
G
A
-
Y
V
Q
K
G
-----------
Q
I
V
A
T
L
D
-------
P
-------------------------------------
K
S
--
P
-
V
R
A
--
P
I
S
G
Y
I
---
L
N
I
T
K
K
I
----
G
E
T
V
N
P
-
Q
S
---
N
--
I
A
V
V
G
-
R
I
-
D
T
K
Q
I
L
T
Y
V
S
E
K
Y
I
S
N
I
K
V
----
G
N
---------
D
A
I
I
E
V
G
A
Y
S
-
N
E
K
F
K
A
K
V
S
E
I
S
P
I
L
D
S
-------------------------
K
S
R
T
I
-
E
V
Y
L
T
P
I
G
S
N
L
D
K
L
I
-------------
I
G
M
F
S
K
I
K
L
I
T
K
R
F
K
D
---
V
----
I
K
I
S
R
E
A
V
V
---
E
R
EG
K
---
K
F
V
F
K
V
D
L
E
S
----
K
S
V
Q
M
L
P
I
T
V
L
F
E
I
D
-
N
I
--
V
A
L
S
G
E
V
----
E
E
N
D
L
I
V
-
V
E
G
M
S
---
A
L
S
N
G
-
S
L
I
N
L
V
D
T
K
E
G
L
SAESNI-
6
HHSearch
61.56
12%
-27
- C5 -
3NE5
-
CUSB_ECOLI
B:
[93-393]
------------------------------------
G
V
K
T
A
T
V
T
R
GPL
T
F
A
Q
S
F
P
A
N
V
S
Y
N
EY--
Q
Y
A
I
V
Q
-
A
R
A
A
G
F
I
D
-------
K
V
Y
P
L
T
-
V
G
D
K
V
Q
K
G
T
P
L
L
D
L
T
I
P
D
W
V
E
A
----
Q
S
E
Y
L
--
L
L
R
E
T
-------
G
G
T
ATQ
T
E
G
I
L
E
R
-
L
R
------------------
L
A
G
-------
M
P
E
-------
A
D
I
R
----
R
L
I
A
T
Q
K
I
Q---------
T
-
R
F
--
T
-
L
K
A
--
P
I
D
G
V
I
---
T
A
F
D
L
R
A
GMN-
I
---
A
K
-
D
N
---
V
--
V
A
K
I
Q
-
G
M
D
P
-
V
W
V
T
A
A
I
P
E
S
I
A
W
L
V
K
D
----
A
S
---------
Q
F
T
L
T
V
P
A
-
R
P
D
K
T
L
T
I
R
K
W
T
L
L
P
G
V
D
A
A
-------------------------------------------
T
R
T
L
Q
L
R
L
E
VD
N
A
D
E
A
L
-
K
P
G
M
N
A
W
L
Q
L
N
T
A
SEP
M
----
L
L
I
P
S
Q
A
L
I
---
D
---
T
GSE
Q
R
V
I
T
V
D
A
D
G
----
R
F
V
P
-
K
R
V
A
V
F
Q
A
-
S
Q
G
V
--
T
A
L
R
S
G
L
----
A
E
G
E
K
V
V
S
S
G
L
-
F
---
L
I
D
S
E
-
A
N
I
S
G
--------------
7
HHSearch
60.58
15%
-25
- C5 -
1VF7
-
MEXA_PSEAE
A:
[26-262]
------------------------------------------------
T
L
N
T
E
L
P
G
R
T
N
A
F
----
R
I
A
E
V
R
-
P
Q
V
N
G
I
I
L
-------
K
R
L
-
F
K
-
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
--
S
T
Q
E
Q
-------
A
Q
R
---
Y
K
L
L
V
A
----
D
Q
A
-----------
V
S
K
Q
Q
Y
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
-
Y
T
--
K
-
V
L
S
--
P
I
S
G
R
I
---
G
R
S
A
V
T
E
G
A
L
-
V
---
T
N
-
G
Q
---
A
NA
M
A
T
V
Q
-
Q
L
D
P
-
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
E
L
A
S
G
Q
LERAGDN
A
A
K
V
S
L
K
L
E
D
-
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
-------------------------------------------
T
G
S
V
T
I
R
A
V
F
P
N
P
N
N
E
L
-
L
P
G
M
F
V
H
A
Q
L
Q
E
G
------------------------------------------------------------------------------------------------------------------
35
Fugue
54.66
14%
-9
- C5 -
1T5E
1
MEXA_PSEAE
A:
[29-259]
---------------------------------------------------
T
E
L
P
G
R
T
N
A
F
----
R
I
A
E
V
-
R
P
Q
V
N
G
I
I
L
-------
K
R
L
-
F
K
-
E
G
S
D
V
K
A
G
Q
Q
L
--
Y
Q
I
D
P
A
T
Y
E
--
A
D
Y
Q
S
A
Q
--
A
N
L
A
S
-------
T
Q
E
---
Q
A
Q
R
Y
K
L
-
L
V
A
D
Q
-----------
A
V
S
K
Q
Q
Y
-------
A
D
A
-------
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
----------
N
-
L
R
Y
T
K
-
V
L
S
--
P
I
S
G
R
I
---
G
R
S
A
V
T
E
G
A
L
V
T
---
N
G
-
Q
A
---
N
--
A
M
A
T
V
-
Q
Q
-
L
-
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
----
R
R
---------
E
L
A
S
G
--
Q
-
L
-
E
R
A
G
D
N
A
A
K
----
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
---
E
G
T
G
S
V
-
T
I
R
A
V
F
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
--
L
-------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
53.86
15%
8
- C1 -
3LD1
-
R1A_IBVM
A:
[5-363]
L
R
D
---------
V
I
L
V
S
K
D
I
P
E
Q
-
L
C
D
A
L
F
------
F
Y
T
S
H
N
P
K
D
---
Y
A
D
A
F
A
V
R
Q
K
F
D
R
----
N
L
Q
T
G
-
K
Q
F
K
F
E
T
V
C
-------
G
L
F
-
L
L
-
K
G
V
D
K
I
T
P
G
V
P
A
K
V
L
K
A
T
S
K
L
A
--
D
L
E
D
I
F
G
VS
P
F
A
R
K
-------
Y
R
E
---
L
L
K
T
A
C
Q
W
S
L
T
V
E
-----------
T
L
D
A
R
A
L
-------
T
L
D
-------
E
I
F
D
P
T
E
I
L
W
L
Q
V
A
A
K
----------
I
-
Q
V
--
S
-
A
M
A
M
R
R
L
V
G
E
V
---
T
A
K
V
M
D
A
----
L
---
G
S
-
N
M
---
S
--
A
L
F
Q
I
-
F
K
-
Q
-
Q
I
V
R
I
F
Q
A
A
L
A
I
F
E
----------------------
N
V
S
E
-
L
-
P
Q
R
I
A
A
L
K
M
A
F
A
K
C
A
K
S
I
T
V
V
V
M
E
R
T
L
V
V
R
E
F
A
-----
G
T
C
L
A
S
I
N
G
-
A
V
A
K
F
F
E
E
L
P
N
G
F
M
G
--
A
K
I
F
T
--
T
F
A
F
F
R
-
E
A
A
V
K
I
V
D
N
I
P
N
A
---
P
----
R
G
T
K
G
F
E
V
V
G
N
A
K
---
G
---
T
Q
V
V
V
R
G
M
R
N
D
L
T
L
L
D
Q
K
-
A
E
I
P
V
E
S
E
-
G
-
W
S
--
A
I
L
G
G
H
L
C
Y
V
F
K
S
G
D
R
F
Y
A
A
P
L
-
S
GNF
A
L
H
D
V
-
H
C
C
E
R
V
V
CL----------
12
HHSearch
52.85
12%
-39
- C5 -
2DN8
-
A:
[10-99]
-------------------------------------------------------
V
F
E
K
E
N
----
D
P
T
V
L
R
-
S
P
S
A
G
K
L
T
-------
Q
Y
T
-
V
E
-
D
G
G
H
V
E
A
G
S
S
Y
A
E
M
E
V
M
K
M
------------------------------------------------------------------------------------------------------------
I
M
--
T
-
L
N
V
--
Q
E
R
G
R
V
---
K
Y
I
-
K
R
P
GAV-
L
---
E
A
-
G
C
---
V
--
V
A
R
L
E
-
L
D
D
P
-
S
K
V
H
P
S
G
P
S
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
52.70
16%
11
* C2 *
4WID
1
?
A:
[10-362]
--
K
D
M
A
L
Q
H
A
V
D
L
L
E
K
M
L
A
D
E
E
K
-
L
T
E
F
N
L
G
D
P
L
F
E
S
A
N
D
D
P
I
K
T
---
L
E
E
I
I
Q
E
G
D
----------
D
V
V
G
A
H
Q
L
V
V
T
Q
I
-------
K
L
R
-
V
Q
-
R
N
R
--
R
L
A
D
E
I
I
R
E
Q
L
T
D
I
-
R
K
--
V
F
S
D
K
F
E
--
K
L
E
Q
G
-------
I
Q
N
---
S
Y
L
L
L
D
K
-------------------
L
K
T
P
F
-------
Q
D
M
-------
R
C
L
F
E
V
A
N
E
Q
F
N
D
T
P
V
----------
P
-
P
Q
--
Y
-
K
E
F
--
M
V
C
L
K
Q
---
I
V
Q
Y
A
V
N
----
S
---
S
S
-
L
E
---
K
--
F
V
M
L
I
-
T
K
-
K
-
D
D
I
K
D
R
V
T
Y
T
C
M
K
Y
L
L
M
----
A
M
---------
Q
------
G
-
T
-
G
G
P
K
A
----------
I
N
N
E
E
H
A
K
L
F
F
Q
--
L
S
N
Y
D
D
L
T
D
A
N
H
D
G
L
E
L
I
-
K
K
L
D
K
E
Q
K
E
V
A
F
H
V
N
N
F
T
H
L
V
T
--
T
L
G
M
A
L
-
Y
K
E
G
H
Q
K
N
D
E
A
M
L
---
G
----
M
H
T
P
I
T
M
L
S
---
D
---
Q
---
V
R
V
L
I
L
Y
L
I
D
----
E
I
V
H
-
A
I
H
T
N
S
N
Q
-
S
-
N
D
--
E
L
I
D
G
L
K
----
P
K
V
R
I
V
I
N
E
F
H
-
A
---
T
L
M
M
G
I
D
K
M
K
F
Y
S
L
N
E
L
R
E
I
V
N
D
K
I
13
HHSearch
50.79
16%
-17
- C5 -
2EJM
-
A:
[4-97]
----------------------------------------------------
G
S
S
G
V
S
S
Q
E
----
T
Q
G
G
P
L
-
A
P
M
T
G
T
I
E
-------
K
V
F
-
V
K
-
A
G
D
K
V
K
A
G
D
S
L
M
V
M
I
A
M
K
M
------------------------------------------------------------------------------------------------------------
E
H
--
T
-
I
K
S
--
P
K
D
G
T
V
---
K
K
V
F
Y
R
E
G
A
Q
-
A
---
N
R
-
H
T
---
P
--
L
V
E
F
E
-
E
E
E
S
-
D
K
R
E
S
E
S
G
P
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
50.48
12%
-31
- C5 -
2KCC
-
A:
[4-82]
-----------------------------------------------------------------
D
P
T
V
L
R
-
S
P
S
A
G
K
L
T
-------
Q
Y
T
-
V
E
-
D
G
G
H
V
E
A
G
S
S
Y
A
E
M
E
V
M
K
M
------------------------------------------------------------------------------------------------------------
I
M
--
T
-
L
N
V
--
Q
E
R
G
R
V
---
K
Y
I
-
K
R
P
GAV-
L
---
E
A
-
G
C
---
V
--
V
A
R
L
E
-
L
D
D
L
-
E
H
H
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
49.75
18%
-20
- C5 -
1BDO
1
BCCP_ECOLI
A:
[4-79]
------------------------------------------------------------------
G
H
I
V
R
-
S
P
M
V
G
T
F
Y
RTPSPDA
K
A
F
-
I
E
-
V
G
Q
K
V
N
V
G
D
T
L
C
I
V
E
A
M
K
M
------------------------------------------------------------------------------------------------------------
M
N
--
Q
-
I
E
A
--
D
K
S
G
T
V
---
K
A
I
L
V
E
S
G
Q
P
-
V
---
E
F
-
D
E
---
P
--
L
V
V
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
49.04
13%
-3
- C2 -
4TKO
2
?
B:
[3-349]
--
H
R
I
E
Y
A
I
T
N
A
V
F
V
K
A
D
E
L
S
Y
L
S
F
R
V
S
G
K
V
I
E
V
Y
K
D
L
G
D
Y
V
K
R
G
---
E
A
L
A
K
L
D
P
T
Y
Y
E
L
----
E
K
R
T
L
E
K
K
M
S
A
L
-----------
L
E
-
K
K
-
K
A
L
E
I
K
I
Q
K
L
E
K
G
L
H
I
S
L
S
A
K
K
--
L
K
V
E
----------------------------
S
L
-
K
K
K
R
E
-----------
A
L
R
E
K
L
L
-------
Q
V
E
-------
E
K
I
K
L
V
K
L
D
W
E
R
Y
K
S
L
----------
F
-
Q
K
--
G
-
L
I
P
--
R
R
K
F
E
E
---
V
D
T
N
L
K
V
----
L
---
L
H
-
E
R
---
E
--
Y
L
E
K
S
-
I
Q
-
E
-
I
N
T
E
I
K
R
A
K
K
G
I
E
N
A
R
N
----
E
F
---------
K
T
I
E
E
L
K
K
-
E
-
L
S
S
L
E
E
E
I
K
S
L
K
E
R
I
K
T
A
E
Q
K
I
K
----
D
T
V
L
I
--
A
P
F
D
G
-
V
V
A
K
R
F
I
-
S
R
G
D
V
V
R
A
G
-----
Q
P
A
F
A
L
V
N
--
P
E
S
F
Y
V
-
E
V
L
L
E
---
E
T
K
L
K
---
G
----
V
K
V
G
N
K
A
Y
V
---
R
---
L
---
D
A
Y
P
D
I
L
F
E
G
----
V
V
E
E
-
I
S
-
P
V
Q
R
I
-
P
-
V
K
--
I
K
I
T
K
G
------------
D
L
S
L
-
L
---
R
V
G
M
G
-
G
E
V
E
I
R
R
T-----------
17
HHSearch
48.81
18%
5
- C5 -
3HBL
1
?
A:
[1059-1146]
------------------------------------------------
D
E
N
V
H
T
N
A
N
V
K
P
K
ADKS
N
P
S
H
I
G
-
A
Q
M
P
G
S
V
T
-------
E
V
K
-
V
S
-
V
G
E
T
V
K
A
N
Q
P
L
L
I
T
E
A
M
K
M
E
------------------------------------------------------------------------------------------------------------
T
--
T
-
I
Q
A
--
P
F
D
G
V
I
---
K
Q
V
T
V
N
N
G
D
T
-
I
---
A
T
-
G
D
---
L
--
L
I
E
I
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
47.69
18%
-15
- C5 -
3VA7
2
?
A:
[1166-1235]
-----------------------------------------------------------------
D
A
E
L
L
Y
-
S
E
Y
T
G
R
F
W
-------
K
P
V
-
A
A
-
V
G
D
H
V
E
A
G
D
G
V
I
I
I
E
A
M
K
T
------------------------------------------------------------------------------------------------------------
E
M
--
V
-
V
G
A
--
T
K
S
G
K
V
---
Y
K
I
L
H
K
N
G
D
M
-
V
---
E
A
-
G
D
---
L
--
V
A
V
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
44.40
8%
-14
- C5 -
3CDX
-
?
A:
[267-342]
------------------------------------------------------------------
D
A
Y
V
M
-
A
P
R
T
G
-
L
F
-------
E
P
T
-
H
Y
-
V
G
E
E
V
R
T
G
E
T
A
G
W
I
H
F
V
E
D
V
D
---------------------------------------------------------------------------------------------
T
----------
A
-
P
L
--
E
-
L
L
Y
--
R
R
D
G
I
V
---
W
F
G
A
G
P
G
R---
V
---
T
R
-
G
D
---
A
--
V
A
V
V
M
-
E
D
Y
N
-
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
42.30
14%
-17
- C5 -
1K8M
-
ODB2_HUMAN
A:
[16-87]
-------------------------------------------------------------------------
I
R
E
V
T
V
K
-------
E
W
Y
-
V
K
-
E
G
D
T
V
S
Q
F
D
S
I
C
E
V
Q
S
D
K
A
------------------------------------------------------------------------------------------------------------
S
V
--
T
-
I
T
S
--
R
Y
D
G
V
I
---
K
K
L
Y
Y
N
L
D
D
I
-
A
---
Y
V
-
G
K
---
P
--
L
V
D
I
E
-
T
E
A
L
-
K
D
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
40.84
16%
-22
* C5 *
1GJX
-
?
A:
[9-78]
--------------------------------------------------------------------
D
I
G
-
G
H
E
N
V
D
I
I
-------
A
V
E
-
V
N
-
V
G
D
T
I
A
V
D
D
T
L
I
T
L
E
T
D
K
A
------------------------------------------------------------------------------------------------------------
T
M
--
D
-
V
P
A
--
E
V
A
G
V
V
---
K
E
V
K
V
K
V
G
D
K
-
I
---
S
E
-
G
G
---
L
--
I
V
V
V
E
-
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
40.37
17%
5
- C5 -
2DNC
-
ODPX_HUMAN
A:
[19-98]
-------------------------------------------------------------------------
M
E
E
G
N
I
V
-------
K
W
L
-
K
K
-
E
G
E
A
V
S
A
G
D
A
L
C
E
I
E
T
D
K
A
------------------------------------------------------------------------------------------------------------
V
V
--
T
-
L
D
A
--
S
D
D
G
I
L
---
A
K
I
V
V
E
E
GSKN
I
---
R
L
-
G
S
---
L
--
I
G
L
I
V
-
E
E
G
E
-
D
W
K
H
V
S
G
P
S
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------