@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1202: (2016-03-23 )
MTILAEIVKYKQSLLQNGYYQDKLNTLKSVKIQNKKSFINAIEKEPKLAIIAEIKSKSPTVNDLPERDLSQQISDYEKYGANAVSILTDEKYFGGSFERLQALTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEVLIEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKPNHHYISESGIHDASDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKVKS
Atome Classification :
(26 SA)
-.........10........20........--30....-....40...---.---....50........60...-..-.-..70........80........90........100.......110.......120.......-130.......140.......150........160...-....170...-.-...180.......190.......200-.....---.-..210.......220.......230.......240-.......250.......260
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
T
I
L
A
E
I
V
K
Y
K
Q
S
L
L
QNGY
Y
Q
D
K
L
N
T
L
K
S
--VKIQ
N
K
-
K
S
F
I
N
A
I
EK---E---P
K
L
A
I
I
A
EIKSKSPTVNDL-
P
E
-
R
-
D
L
S
Q
Q
I
S
D
Y
E
K
YGA
N
A
V
S
I
LTDEKYFG
G
S
F
E
R
L
Q
A
L
T
TKT
T
L
P
V
L
C
K
D
FIIDP
L
Q
I
D
V
A
K
QA-G
A
S
M
I
L
L
I
V
N
I
LS
D
K
Q
L
K
D
L
Y
-
N
Y
A
ISQN
L
E
V
L
I
E
VH-
D
R
H
E
L
E
R
A
YK-V-
N
A
K
L
I
GV
N
N
R
D
L
K
R
F
V
T
NVE
H
T
N
T
I
--LENKK---P-NHHYISESGIH
D
A
S
D
V
R
K
I
L
H
SGID
G
L
L
I
G
E
A
L
M
R-CD
N
L
S
E
F
L
P
Q
L
K
M
Q
K
VKS
55
HHSearch
92.28
34%
-96
- C3 -
3TSM
3
TRPC_BRUA2
A:
[8-268]
--
D
I
L
R
K
I
E
A
Y
K
R
E
E
I
A
A
A
K
A
R
L
A
L
D
E
L
K
A
R
T
R
D
Q
S
A
P
-
R
G
F
L
K
A
L
E
A
K
R
A
A
---
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
-
R
P
-
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
-
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
-
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
--
A
K
M
A
P
---
S
-
D
R
L
L
V
G
E
S
G
I
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
-
Q
H
D
V
A
A
A
T
R
A
L
L
T
G
----
56
HHSearch
91.54
31%
-94
- C3 -
1I4N
1
TRPC_THEMA
A:
[1-248]
--
R
R
L
W
E
I
V
E
A
K
K
K
D
I
L
E
I
D
G
E
N
-
L
I
-------
V
Q
R
R
N
-
H
R
F
L
E
V
L
S
G
---
K
---
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
-
N
A
-
D
A
S
L
E
D
F
I
R
M
Y
D
E
-
L
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
D
T
V
Q
V
K
L
A
S
S
V
-
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
-
E
A
A
E
E
L
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
-
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
--
L
P
L
V
P
---
D
-
D
T
V
V
V
A
E
S
G
I
K
D
P
R
E
L
K
D
L
R
-
G
K
V
N
A
V
L
V
G
T
S
I
M
K
-
A
E
N
P
R
R
F
L
E
E
M
R
A
-----
59
HHSearch
90.37
34%
-94
* C3 *
1VC4
6
?
A:
[10-253]
--
G
V
L
G
E
I
A
R
K
R
A
S
E
V
A
P
Y
----
P
L
P
E
-------
P
P
S
V
-
P
S
F
K
E
A
L
L
----
R
---
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
-
R
E
-
V
-
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
A
L
L
G
E
-
L
T
G
A
Y
L
-
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
-
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
--
G
R
L
A
R
K
R
G
F
-
G
G
V
L
V
A
E
S
G
Y
S
R
K
E
E
L
K
A
L
E
G
-
L
F
D
A
V
L
I
G
T
S
L
M
R
-
A
P
D
L
E
A
A
L
R
E
L
V
------
8
PsiBlast_PDB
88.41
36%
-95
- C3 -
3TSM
3
TRPC_BRUA2
A:
[9-254]
---
I
L
R
K
I
E
A
Y
K
R
E
E
I
A
A
A
K
A
R
L
A
L
D
E
L
K
A
R
-
T
R
D
Q
S
A
P
R
G
F
L
K
A
L
E
A
---
K
R
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
-
F
-
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
-
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
-
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
--
A
K
M
A
P
---
S
-
D
R
L
L
V
G
E
S
G
I
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
-------------------
16
PsiBlast_PDB
88.37
33%
-102
- C3 -
1I4N
1
TRPC_THEMA
A:
[31-247]
-----------------------------------------
F
L
E
V
L
S
G
---
K
---
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
-
A
-
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
D
T
V
Q
V
K
L
A
S
S
V
-
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
-
E
A
A
E
E
L
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
-
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
--
L
P
L
V
P
---
D
-
D
T
V
V
V
A
E
S
G
I
K
D
P
R
E
L
-
K
D
L
R
G
K
V
N
A
V
L
V
G
T
S
I
M
K
-
A
E
N
P
R
R
F
L
E
E
M
R
------
21
PsiBlast_CBE
88.21
36%
-94
- C3 -
3TSM
5
TRPC_BRUA2
B:
[9-254]
---
I
L
R
K
I
E
A
Y
K
R
E
E
I
A
A
A
K
A
R
L
A
L
D
E
L
K
A
R
-
T
R
D
Q
S
A
P
R
G
F
L
K
A
L
E
A
---
K
R
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
-
F
-
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
-
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
-
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
--
A
K
M
A
P
---
S
-
D
R
L
L
V
G
E
S
G
I
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
-------------------
22
PsiBlast_CBE
87.91
33%
-106
- C3 -
1I4N
1
TRPC_THEMA
B:
[31-247]
-----------------------------------------
F
L
E
V
L
S
G
---
K
---
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
-
A
-
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
D
T
V
Q
V
K
L
A
S
S
V
-
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
-
E
A
A
E
E
L
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
-
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
--
L
P
L
V
P
---
D
-
D
T
V
V
V
A
E
S
G
I
K
D
P
R
E
L
-
K
D
L
R
G
K
V
N
A
V
L
V
G
T
S
I
M
K
-
A
E
N
P
R
R
F
L
E
E
M
R
------
19
PsiBlast_PDB
87.77
37%
-100
- C3 -
1VC4
6
?
A:
[36-252]
----------------------------------------
S
F
K
E
A
L
L
R
-------
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
-
R
E
-
V
-
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
A
L
L
G
--
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
-
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
G
R
L
A
R
K
R
---
G
F
G
G
V
L
V
A
E
S
G
Y
S
R
K
E
E
L
-
K
A
L
E
G
L
F
D
A
V
L
I
G
T
S
L
M
R
-
A
P
D
L
E
A
A
L
R
E
L
-------
3
PsiBlast_PDB
87.50
39%
-108
- C3 -
1JUL
1
TRPC_SULSO
A:
[47-247]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
57
HHSearch
87.10
35%
-89
- C3 -
1PII
1
TRPC_ECOLI
A:
[2-256]
-
Q
T
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
Q
Q
Q
P
L
A
S
F
Q
N
--
E
V
Q
P
S
T
-
R
H
F
Y
D
A
L
Q
----
G
---
A
R
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
-
R
D
-
D
F
D
P
A
R
I
A
A
I
Y
K
-
H
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
Y
Y
-
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
-
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
-
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
S
I
D
L
N
R
T
R
E
L
--
A
P
K
L
G
---
H
-
N
V
T
V
I
S
E
S
G
I
N
T
Y
A
Q
V
R
E
L
S
-
H
F
A
N
G
F
L
I
G
S
A
L
M
A
-
H
D
D
L
H
A
A
V
R
R
V
L
L
G
E
---
23
PsiBlast_CBE
86.34
37%
-102
- C3 -
1VC4
8
?
B:
[36-252]
----------------------------------------
S
F
K
E
A
L
L
R
-------
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
-
R
E
-
V
-
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
A
L
L
G
--
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
-
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
GR
L
A
R
K
R
---
G
F
G
G
V
L
V
A
E
S
G
Y
S
R
K
E
E
L
-
K
A
L
E
G
L
F
D
A
V
L
I
G
T
S
L
M
R
-
A
P
D
L
E
A
A
L
R
E
L
-------
6
PsiBlast_PDB
85.41
39%
-107
- C3 -
1A53
1
TRPC_SULSO
A:
[46-246]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
5
PsiBlast_PDB
84.63
39%
-103
- C3 -
1LBL
1
TRPC_SULSO
A:
[46-246]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
4
PsiBlast_PDB
84.50
39%
-103
- C3 -
1LBF
1
TRPC_SULSO
A:
[46-246]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
1
PsiBlast_PDB
84.23
39%
-103
- C3 -
1IGS
1
TRPC_SULSO
A:
[47-247]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
15
PsiBlast_PDB
83.98
33%
-106
- C3 -
1J5T
-
TRPC_THEMA
A:
[22-238]
-----------------------------------------
F
L
E
V
L
S
G
---
K
---
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
-
A
-
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
D
T
V
Q
V
K
L
A
S
S
V
-
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
-
E
A
A
E
E
L
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
-
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
--
L
P
L
V
P
---
D
-
D
T
V
V
V
A
E
S
G
I
K
D
P
R
E
L
-
K
D
L
R
G
K
V
N
A
V
L
V
G
T
S
I
M
K
-
A
E
N
P
R
R
F
L
E
E
M
R
------
58
HHSearch
83.20
30%
-94
- C3 -
3QJA
1
TRPC_MYCTU
A:
[4-261]
-
A
T
V
L
D
S
I
L
E
G
V
R
A
D
V
A
A
R
E
A
S
V
S
L
S
E
I
K
A
A
A
A
A
A
P
P
P
-
L
D
V
M
A
A
L
R
----
E
---
P
G
I
G
V
I
A
E
V
K
---------------
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
-
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
-
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
--
A
P
G
L
P
---
S
-
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
T
-
S
G
D
P
R
A
A
V
A
D
L
V
T
A
----
46
Fugue
82.20
34%
-86
- C3 -
1PII
1
?
?:
[1-255]
M
Q
T
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
Q
Q
Q
P
L
A
S
F
Q
N
--
E
V
Q
P
S
T
-
R
H
F
Y
D
A
L
Q
G
---
A
---
R
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
-
D
D
-
F
-
D
P
A
R
I
A
A
I
Y
K
H
-
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
-
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
-
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
N-
E
E
E
Q
E
R
A
I
A
-
L
-
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
S
I
D
L
N
R
T
R
E
L
--
A
P
K
L
G
---
H
-
N
V
T
V
I
S
E
S
G
I
N
T
Y
A
Q
V
R
E
L
S
H
-
F
A
N
G
F
L
I
G
S
A
L
M
A
-
H
D
D
L
H
A
A
V
R
R
V
L
L
G
----
10
PsiBlast_PDB
82.04
36%
-83
- C3 -
1JCM
6
TRPC_ECOLI
P:
[3-245]
--
C
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
Q
Q
Q
P
L
A
S
F
Q
N
--
E
V
Q
P
S
T
-
R
H
F
Y
D
A
L
Q
G
---
A
----
R
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
-
R
D
-
D
-
F
D
P
A
R
I
A
A
I
Y
K
H
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
Y
Y
-
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
-
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
-
G
A
K
V
V
G
I
N
N
R
D
L
C
D
L
S
I
D
L
N
R
T
R
E
L
--
A
P
K
L
G
---
H
-
N
V
T
V
I
S
E
S
G
I
N
T
Y
A
Q
V
R
E
L
S
H
F
A
-
N
G
F
L
I
G
S
A
L
M
A
-
H
D
D
L
--------------
2
PsiBlast_PDB
81.41
39%
-102
- C3 -
1JUK
1
TRPC_SULSO
A:
[47-247]
----------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
E
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
P
E
K
I
K
E
F
I
----------
12
PsiBlast_PDB
78.87
34%
-92
- C3 -
3T44
2
TRPC_MYCTU
A:
[43-246]
------------------------------------------
V
M
A
A
L
R
---
E
---
P
G
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
-
A
T
I
A
-
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
-
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
-
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
--
A
P
G
L
P
---
S
-
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
--------------------
14
PsiBlast_PDB
77.86
34%
-93
- C3 -
3T78
5
TRPC_MYCTU
A:
[43-246]
------------------------------------------
V
M
A
A
L
R
---
E
---
P
G
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
-
A
T
I
A
-
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
-
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
-
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
R
D
C
F
A
R
I
--
A
P
G
L
P
---
S
-
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
--------------------
11
PsiBlast_PDB
77.44
34%
-100
- C3 -
3T40
3
TRPC_MYCTU
A:
[43-246]
------------------------------------------
V
M
A
A
L
R
---
E
---
P
G
I
G
V
I
A
E
V
K
R
----------
T
I
A
-
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
-
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
-
G
A
K
V
I
G
V
N
A
R
-----
D
V
D
R
D
C
F
A
R
I
--
A
P
G
L
P
---
S
-
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
--------------------
13
PsiBlast_PDB
76.76
34%
-91
- C3 -
3T55
3
TRPC_MYCTU
A:
[43-246]
------------------------------------------
V
M
A
A
L
R
---
E
---
P
G
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
-
A
T
I
A
-
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
-
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
-
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
--
A
P
G
L
P
---
S
-
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
--------------------
28
PsiBlast_CBE
70.29
35%
-94
- C3 -
3UXD
4
?
A:
[47-238]
----------------------------------------------------------
A
I
I
A
V
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
A
K
F
M
E
R
Y
A
V
G
L
V
-
I
L
T
E
E
K
Y
F
N
G
S
Y
E
D
L
R
K
I
A
S
S
V
S
I
P
I
L
M
W
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
G
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
A
I
V
I
N
-
D
E
E
D
L
D
I
A
L
R
-
I
-
G
A
R
I
I
I
I
S
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
A
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
E
I
G
S
S
L
M
R
-------------------
27
PsiBlast_CBE
68.39
35%
-92
- C3 -
3UXD
5
?
B:
[47-238]
----------------------------------------------------------
A
I
I
A
V
Y
K
R
K
S
P
S
G
L
D
V
--
E
-
R
-
D
P
I
E
Y
A
K
F
M
E
R
Y
A
V
G
L
V
-
I
L
T
E
E
K
Y
F
N
G
S
Y
E
D
L
R
K
I
A
S
S
V
S
I
P
I
L
M
W
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
G
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
-
E
Y
A
R
S
Y
G
M
E
P
A
I
V
I
N
-
D
E
E
D
L
D
I
A
L
R
-
I
-
G
A
R
I
I
I
I
S
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
--
I
S
M
I
P
---
S
-
N
V
V
K
V
A
A
S
G
I
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
E
I
G
S
S
L
M
R
-------------------