@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0013: (2016-04-18 )
MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVAGQFDGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRVTARTSSGVIMAVQHTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA
Atome Classification :
(20 SA)
-.........10........20........30..-......40.......--.50....-...-.---60---------------.---.-.---......70----...--.....80........90........100-------..-.--------------.....-110-------------------------------.-.---.---....120..--------.--....130.......------140.......150........160...--....170.......--180.......-190........200.......210.......220.......230
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-
M
R
I
L
V
VDN
Y
D
S
F
V
F
N
L
V
Q
Y
L
G
QLG
I
E
A
E
V
WRND-DHRLSDEAAVAGQFD--
G
V
L
LSPG-PGT-P---E----------------R---A-G---AS
V
S
I
V
H
A
----
C
A
A--AHT
P
L
L
G
V
C
LGH
Q
A
I
G
VAFGATVDRA
P
--------
E
L
-L--------------HGKTS-
S
V
F
-------------------------------H-T---N---V
G
V
LQGLPD--------P--FTAT
R
Y
H
S
L
T
ILPK------S
L
P
A
V
L
R
V
T
ART-SS
G
V
I
M
A
V
QHTGLP--IHG
V
Q
FH
P
E
S
I
L
T
E--GG
H
R
I
L
A
N
W
L
-
T
-CCGWTQ
D
D
T
L
V
R
R
L
E
N
E
V
L
T
A
ISPHFPTSTASAGEATGRTSA
54
Fugue
98.57
45%
-123
* C2 *
1QDL
-
TRPG_SULSO
B:
[1-195]
M
D
L
T
L
I
I
D
N
Y
D
S
F
V
Y
N
I
A
Q
I
V
G
E
L
G
S
Y
P
I
V
I
R
N
D
-
E
--
I
S
I
K
G
I
E
R
I
D
P
D
--
R
L
I
I
S
P
G
-
P
G
T
-
P
EKR
E
----------------
D
---
I
-
G
---
V
S
L
D
V
I
K
Y
----
L
G
K
---
R
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
--------
K
V
-
F
--------------
H
G
K
I
S
-
N
I
I
L
VN----------------------------
N
-
S
---
P
---
L
S
L
Y
Y
G
I
A
----------K
E
F
K
A
T
R
Y
H
S
L
V
V
D
--------
E
V
H
R
P
L
I
V
D
A
I
S
A
E
D
N
E
I
M
A
I
H
H
E
E
Y
P
--
I
Y
G
V
Q
F
H
P
E
S
V
G
T
S
--
L
G
Y
K
I
L
Y
N
F
L
-
N
-
R
V
----------------------------------------
39
HHSearch
95.78
44%
-115
- C2 -
1QDL
-
TRPG_SULSO
B:
[2-195]
-
D
L
T
L
I
I
D
N
Y
D
S
F
V
Y
N
I
A
Q
I
V
G
E
L
G
S
Y
P
I
V
I
R
N
D
-
E
I
S
I
K
G
I
--
E
R
I
D
P
D
--
R
L
I
I
S
P
G
-
P
G
T
-
P
---
E
----------------
K
---
R
-
E
DIG
V
S
L
D
V
I
K
Y
-----
L
G
--
K
R
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
--------
K
V
-
F
--------------
H
G
K
I
S
-
N
I
I
-------------------------------
L
-
V
NNS
P
---
L
S
L
Y
Y
G
I
A
K
--------
E
--
F
K
A
T
R
Y
H
S
L
V
V
D
--------
E
V
H
R
P
L
I
V
D
A
I
S
A
E
D
N
E
I
M
A
I
H
H
E
E
Y
P
--
I
Y
G
V
Q
F
H
P
E
S
V
G
T
S
--
L
G
Y
K
I
L
Y
N
F
L
-
N
-
R
V
----------------------------------------
1
PsiBlast_PDB
90.85
43%
-107
- C2 -
1QDL
-
TRPG_SULSO
B:
[5-193]
----
L
I
I
D
N
Y
D
S
F
V
Y
N
I
A
Q
I
V
G
E
L
G
S
Y
P
I
V
I
R
N
D
-
E
--
I
S
I
K
G
I
E
R
I
D
P
D
--
R
L
I
I
S
P
G
-
P
G
T
-
P
---
E
----------------
K
RED
I
-
G
---
V
S
L
D
V
I
K
Y
----
L
G
K
---
R
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
--------
K
V
-
F
--------------
H
G
K
I
S
-
N
I
I
-------------------------------
L
-
V
---
N
NSP
L
S
L
Y
Y
G
I
A
K
--------
E
--
F
K
A
T
R
Y
H
S
L
V
V
D
E
V
------
H
R
P
L
I
V
D
A
I
S
-
A
-
E
D
N
E
I
M
A
I
H
H
E
E
Y
P
--
I
Y
G
V
Q
F
H
P
E
S
V
G
T
S
--
L
G
Y
K
I
L
Y
N
F
L
-
N
-------------------------------------------
2
PsiBlast_PDB
85.80
40%
-111
- C2 -
1I7Q
1
TRPG_SERMA
B:
[4-187]
---
I
L
L
L
D
N
V
D
S
F
T
Y
N
L
V
D
Q
L
R
A
S
G
H
Q
V
V
I
Y
R
N
Q
I
G
A
E
V
I
I
E
R
L
Q
H
M
E
Q
P
--
V
L
M
L
S
P
G
-
P
G
T
-
P
---
S
----------------
E
---
A
-
G
---
C
M
P
E
L
L
Q
R
----
L
R
G
---
Q
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
--------
E
I
-
L
--------------
H
G
K
A
S
-
A
I
A
-------------------------------
H
-
D
---
G
---
E
G
M
F
A
G
M
A
N
--------
P
--
L
P
V
A
R
Y
H
S
L
--
V
G
S
------
N
I
P
A
D
L
T
V
N
A
R
F
-
G
E
-
M
V
M
A
V
R
D
D
R
R
R
--
V
C
G
F
Q
F
H
P
E
S
I
L
T
T
--
H
G
A
R
L
L
E
Q
T
L
---------------------------------------------
21
PsiBlast_CBE
85.62
40%
-110
- C2 -
1I7Q
1
TRPG_SERMA
D:
[4-187]
---
I
L
L
L
D
N
V
D
S
F
T
Y
N
L
V
D
Q
L
R
A
S
G
H
Q
V
V
I
Y
R
N
Q
I
G
A
E
V
I
I
E
R
L
Q
H
M
E
Q
P
--
V
L
M
L
S
P
G
-
P
G
T
-
P
---
S
----------------
E
---
A
-
G
---
C
M
P
E
L
L
Q
R
----
L
R
G
---
Q
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
--------
E
I
-
L
--------------
H
G
K
A
S
-
A
I
A
-------------------------------
H
-
D
---
G
---
E
G
M
F
A
G
M
A
N
--------
P
--
L
P
V
A
R
Y
H
S
L
--
V
G
S
------
N
I
P
A
D
L
T
V
N
A
R
F
-
G
E
-
M
V
M
A
V
R
D
D
R
R
R
--
V
C
G
F
Q
F
H
P
E
S
I
L
T
T
--
H
G
A
R
L
L
E
Q
T
L
---------------------------------------------
3
PsiBlast_PDB
82.77
40%
-109
- C2 -
1I7S
-
TRPG_SERMA
B:
[4-187]
---
I
L
L
L
D
N
V
D
S
F
T
Y
N
L
V
D
Q
L
R
A
S
G
H
Q
V
V
I
Y
R
N
Q
I
G
A
E
V
I
I
E
R
L
Q
H
M
E
Q
P
--
V
L
M
L
S
P
G
-
P
G
T
-
P
---
S
----------------
E
---
A
-
G
---
C
M
P
E
L
L
Q
R
----
L
R
G
---
Q
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
--------
E
I
-
L
--------------
H
G
K
A
S
-
A
I
A
-------------------------------
H
-
D
---
G
---
E
G
M
F
A
G
M
A
N
--------
P
--
L
P
V
A
R
Y
H
S
L
--
V
G
S
------
N
I
P
A
D
L
T
V
N
A
R
F
-
G
E
-
M
V
M
A
V
R
D
D
R
R
R
--
V
C
G
F
Q
F
H
P
E
S
I
L
T
T
--
H
G
A
R
L
L
E
Q
T
L
---------------------------------------------
4
PsiBlast_PDB
80.52
31%
-108
- C2 -
2D7J
-
GUAAA_PYRHO
A:
[2-187]
--
M
I
V
I
M
D
N
G
G
Q
Y
V
H
R
I
W
R
T
L
R
Y
L
G
V
E
T
K
I
I
P
N
T
-
T
---
P
L
E
E
I
K
A
M
N
P
K
--
G
I
I
F
S
G
G
-
P
S
L
-----
E
----------------
N
---
T
-
G
---
N
C
E
K
V
L
E
H
----
Y
D
E
--
F
N
V
P
I
L
G
I
C
L
G
H
Q
L
I
A
K
F
F
G
G
K
V
G
R
G
E
--------
K
A
-
E
--------------
Y
S
L
V
E
-
I
E
I
-------------------------------
I
-
D
---
E
---
D
E
I
F
K
G
L
P
K
--------
R
--
L
K
V
W
E
S
H
M
D
E
V
--
K
------
E
L
P
P
K
F
K
I
L
A
R
S
-
E
T
C
P
I
E
A
M
K
H
E
E
L
P
--
I
Y
G
V
Q
F
H
P
E
V
A
H
T
E
--
K
G
E
E
I
L
R
N
F
A
-
K
-
L
C
G
---------------------------------------
6
PsiBlast_PDB
79.62
30%
-110
- C2 -
2A9V
3
GUAAA_THEAC
A:
[14-199]
-
L
K
I
Y
V
V
D
N
G
G
Q
W
T
H
R
E
W
R
V
L
R
E
L
G
V
D
T
K
I
V
P
N
D
-----
I
D
S
S
E
L
D
G
-
L
D
--
G
L
V
L
S
G
G
A
P
N
I
-
D
---
E
----------------
E
---
L
-
D
---
K
L
G
S
V
G
K
Y
----
I
D
D
--
H
N
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
L
H
F
G
A
S
V
V
K
A
K
--------
H
P
-
E
--------------
F
G
K
T
K
V
S
V
M
-------------------------------
H
-
S
---
E
----
N
I
F
G
G
L
P
S
--------
E
--
I
T
V
W
E
N
H
N
D
E
I
I
--------
N
L
P
D
D
F
T
L
A
A
S
S
-
A
T
C
Q
V
Q
G
F
Y
H
K
T
R
P
--
I
Y
A
T
Q
F
H
P
E
V
E
H
T
Q
--
Y
G
R
D
I
F
R
N
F
I
-
G
-
I
C
----------------------------------------
28
HHSearch
78.89
27%
-104
- C2 -
2A9V
3
GUAAA_THEAC
A:
[14-207]
-
L
K
I
Y
V
V
D
N
G
G
Q
W
T
H
R
E
W
R
V
L
R
E
L
G
V
D
T
K
I
V
P
N
D
-
I
D
S
S
-----
E
L
D
G
L
D
--
G
L
V
L
S
G
G
-
A
P
N
-
I
---
D
----------------
E
---
E
L
D
---
K
L
G
S
V
G
K
Y
----
I
D
D
--
H
N
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
L
H
F
G
A
S
V
V
K
A
K
--------
H
P
-
E
--------------
F
G
K
T
K
-
V
S
V
-------------------------------
M
-
H
---
S
---
E
N
I
F
G
G
L
P
S
--------
E
--
I
T
V
W
E
N
H
N
D
E
I
I
--------
N
L
P
D
D
F
T
L
A
A
S
S
-
A
T
C
Q
V
Q
G
F
Y
H
K
T
R
P
--
I
Y
A
T
Q
F
H
P
E
V
E
H
T
Q
--
Y
G
R
D
I
F
R
N
F
I
-
G
-
I
C
A
S
Y
R
E
I
Q
K
--------------------------------
36
HHSearch
76.66
21%
-110
- C2 -
3UOW
-
?
A:
[9-274]
--
K
I
L
V
L
N
F
G
S
Q
Y
F
H
L
I
V
K
R
L
N
N
I
K
I
F
S
E
T
K
D
Y
G
-
V
E
L
K
D
-
I
--
K
D
M
N
I
K
--
G
V
I
L
S
G
G
-
P
Y
S
-
V
---
T
----------------
E
---
A
-
G
SPH
L
K
K
E
V
F
E
Y
----
F
L
E
--
K
K
I
P
I
F
G
I
C
Y
G
M
Q
E
I
A
V
Q
M
N
G
E
V
K
K
S
K
--------
T
S
-
E
--------------
Y
G
C
T
D
-
V
N
I
L
R
NDNINNITYCRNFSS
A
M
D
L
Y
S
N
Y
K
L
M
---
N
---------
C
C
L
F
E
N
I
K
S
D-------
I
--
T
T
V
W
M
N
H
N
D
E
V
T
--------
K
I
P
E
N
F
Y
L
V
S
S
S
-
E
N
C
L
I
C
S
I
Y
N
K
E
Y
N
--
I
Y
G
V
Q
Y
H
P
E
V
Y
E
S
L
--
D
G
E
L
M
F
Y
N
F
A
Y
N
-
I
C
K
C
K
K
-
F
D
P
I
R
Y
H
E
L
E
L
K
-----------------------
37
HHSearch
76.60
21%
-110
- C2 -
4WIN
3
?
A:
[19-245]
-
D
K
I
L
V
L
N
F
G
S
Q
Y
F
H
L
I
V
K
R
L
N
N
I
K
I
F
S
E
T
K
D
Y
G
-
V
E
L
K
-
D
I
--
K
D
M
N
I
K
--
G
V
I
L
S
G
G
-
P
Y
S
-
V
---
T
----------------
E
---
A
-
G
SPH
L
K
K
E
V
F
E
Y
----
F
L
E
--
K
K
I
P
I
F
G
I
C
Y
G
M
Q
E
I
A
V
Q
M
N
G
E
V
K
K
S
K
--------
T
S
-
E
--------------
Y
G
C
T
D
-
V
N
I
L
R
NDNINNITYCRNFGDSSS
A
M
D
L
Y
S
N
Y
K
L
M
N
-
E
---
T
---
C
C
L
F
E
N
I
K
S
D-------
I
--
T
T
V
W
M
N
H
N
D
E
V
T
--------
K
I
P
E
N
F
Y
L
V
S
S
S
-
E
N
C
L
I
C
S
I
Y
N
K
E
Y
N
--
I
Y
G
V
Q
Y
H
P
E
V
Y
E
S
L
--
D
G
E
L
M
F
Y
N
F
A
-
Y
N
I
C
K
C
K
K
------------------------------------
5
PsiBlast_PDB
75.79
30%
-100
- C2 -
2LXN
-
GUAAA_METJA
A:
[2-186]
---
I
V
I
L
D
N
G
G
Q
Y
V
H
R
I
H
R
S
L
K
Y
I
G
V
S
S
K
I
V
P
N
T
-
T
P
L
--
E
E
I
E
S
N
K
E
V
K
--
G
I
I
L
S
G
G
-
P
D
I
-----
E
----------------
K
---
A
-
K
---
N
C
I
D
I
A
-------
L
N
--
A
K
L
P
I
L
G
I
C
L
G
H
Q
L
I
A
L
A
Y
G
G
E
V
G
R
A
E
--------
A
E
-
E
--------------
Y
A
L
T
K
-
V
Y
V
-------------------------------
D
-
K
---
E
---
N
D
L
F
K
N
V
P
R
--------
E
--
F
N
A
W
A
S
H
K
D
E
V
--
K
------
K
V
P
E
G
F
E
I
L
A
H
S
-
D
I
C
Q
V
E
A
M
K
H
K
T
K
P
--
I
Y
G
V
Q
F
H
P
E
V
A
H
T
E
--
Y
G
N
E
I
L
K
N
F
C
-
K
-
V
C
G
Y
K
-------------------------------------
31
HHSearch
73.41
28%
-100
- C2 -
2LXN
-
GUAAA_METJA
A:
[1-186]
--
M
I
V
I
L
D
N
G
G
Q
Y
V
H
R
I
H
R
S
L
K
Y
I
G
V
S
S
K
I
V
P
N
T
-
T
P
L
E
E
I
--
E
S
N
K
E
V
K
--
G
I
I
L
S
G
G
-
P
D
I
-
E
---
K
---------------------------
A
K
N
C
I
D
I
----
A
L
N
--
A
K
L
P
I
L
G
I
C
L
G
H
Q
L
I
A
L
A
Y
G
G
E
V
G
R
A
E
--------
A
E
-
E
--------------
Y
A
L
T
K
-
V
Y
V
-------------------------------
D
-
K
---
E
---
N
D
L
F
K
N
V
P
R
--------
E
--
F
N
A
W
A
S
H
K
D
E
V
K
--------
K
V
P
E
G
F
E
I
L
A
H
S
-
D
I
C
Q
V
E
A
M
K
H
K
T
K
P
--
I
Y
G
V
Q
F
H
P
E
V
A
H
T
E
--
Y
G
N
E
I
L
K
N
F
C
-
K
-
V
C
G
Y
K
-------------------------------------
18
PsiBlast_PDB
73.28
27%
-116
- C2 -
3R74
-
?
A:
[446-629]
--
R
A
L
I
V
D
A
E
D
H
F
T
A
M
I
A
Q
Q
L
S
S
L
G
L
A
T
E
V
C
G
V
H
-
D
------
A
V
D
L
A
R
Y
D
--
V
V
V
M
G
P
G
-
P
G
D
-
P
---
S
----------------
D
---
A
-
G
D--
P
R
I
A
R
L
Y
A
W
L
R
H
L
I
D
--
E
G
K
P
F
M
A
V
C
L
S
H
Q
I
L
N
A
I
L
G
I
P
L
V
R
R
E
V
P
N
Q
G
I
Q
V
E
I
D
L
--------------
F
G
Q
R
E
-
R
V
G
-------------------------------
F
-
Y
---
N
---
T
Y
V
A
Q
T
V
R
D
--------
E
--
M
D
V
D
G
V
G
T
V
A
I
-----------------
S
R
D
P
-
R
T
G
E
V
H
A
L
R
--
G
P
T
--
F
S
S
M
Q
F
H
A
E
S
V
L
T
V
--
D
G
P
R
I
L
G
E
A
I
-
T
-------------------------------------------
43
HHSearch
73.27
25%
-120
- C2 -
3FIJ
1
?
A:
[30-244]
-------------
Q
Q
R
Y
V
D
A
I
Q
K
V
G
G
F
P
I
A
L
P
I
D
-
D
P
S
T
--
A
V
Q
A
I
S
L
V
D
--
G
L
L
L
T
G
G
-
Q
D
I
T
P
---
Q
LYLEEPSQEIGAYF
P
P
R
---
D
-
S
---
Y
E
I
A
L
V
R
A
----
A
L
D
--
A
G
K
P
I
F
A
I
C
R
G
M
Q
L
V
N
V
A
L
G
G
T
L
Y
Q
D
I
--------
S
Q
-
V
ETKALQHLQRVDEQ
L
G
S
-
H
-
T
I
D
-------------------------------
I
E
P
---
T
---
S
E
L
A
K
H
H
P
N
--------
K
--
K
L
V
N
S
L
H
H
Q
F
I
K
--------
K
L
A
P
S
F
K
V
T
A
R
T
-
A
D
G
M
I
E
A
V
E
G
D
N
L
P
S
W
Y
L
G
V
Q
W
H
P
E
L
M
F
Q
T
D
P
E
S
E
Q
L
F
Q
A
L
V
-
D
-
E
S
K
K
T
M
------------------------------------
30
HHSearch
73.18
26%
-105
- C2 -
2YWB
-
GUAA_THET8
A:
[1-228]
--
M
V
L
V
L
D
F
G
S
Q
Y
T
R
L
I
A
R
R
L
R
E
L
R
A
F
S
L
I
L
P
G
D
-
A
P
L
E
E
-
V
--
L
K
H
R
P
Q
--
A
L
I
L
S
G
G
-
P
R
S
-
V
---
F
----------------
D
---
P
-
D
---
A
-
P
R
P
D
P
R
----
L
F
S
--
S
G
L
P
L
L
G
I
C
Y
G
M
Q
L
L
A
Q
E
L
G
G
R
V
E
R
A
------------
E
--------------
Y
G
K
A
L
--
L
T
-------------------------------
R
-
H
---
E
---
G
P
L
F
R
G
L
E
G
--------
E
--
V
Q
V
W
M
S
H
Q
D
A
V
T
--------
A
P
P
P
G
W
R
V
V
A
E
T
-
E
E
N
P
V
A
A
I
A
S
P
D
G
R
--
A
Y
G
V
Q
F
H
P
E
V
A
H
T
P
--
K
G
M
Q
I
L
E
N
F
L
-
E
-
L
A
G
V
K
R
D
W
T
P
E
H
V
L
E
E
L
-------------------------
34
HHSearch
72.92
24%
-116
- C2 -
3TQI
-
GUAA_COXBU
A:
[8-260]
-
H
R
I
L
I
L
D
F
G
S
Q
Y
A
Q
L
I
A
R
R
V
R
E
I
G
V
Y
C
E
L
M
P
C
D
-
I
D
E
E
T
-
I
--
R
D
F
N
P
H
--
G
I
I
L
S
G
G
-
P
E
-------------------------------------
A
P
A
F
----
I
F
E
--
I
G
C
P
V
L
G
I
C
Y
G
M
Q
T
M
A
Y
Q
L
G
G
K
V
N
--------------
E
--------------
F
G
H
A
Q
-
L
R
V
-------------------------------
L
-
N
---
P
---
A
F
L
F
D
G
I
E
D
QVSPQG
E
P
L
--
L
D
V
W
M
S
H
G
D
I
V
S
--------
E
L
P
P
G
F
E
A
T
A
C
T
-
D
N
S
P
L
A
A
M
A
D
F
K
R
R
--
F
F
G
L
Q
F
H
P
E
V
T
H
T
P
--
Q
G
H
R
I
L
A
H
F
V
I
H
-
I
C
Q
C
I
P
N
W
T
T
K
H
I
I
E
D
S
I
R
-----------------------
33
HHSearch
71.66
22%
-98
- C2 -
1GPM
1
GUAA_ECOLI
A:
[8-239]
-
H
R
I
L
I
L
D
F
G
S
Q
Y
T
Q
L
V
A
R
R
V
R
E
L
G
V
Y
C
E
L
W
A
W
D
-
V
T
E
A
Q
-
I
--
R
D
F
N
P
S
--
G
I
I
L
S
G
G
-
P
E
S
-
T
---
T
----------------
E
---
E
-
N
---
S
-
P
R
A
P
Q
Y
----
V
F
E
--
A
G
V
P
V
F
G
V
C
Y
G
M
Q
T
M
A
M
Q
L
G
G
H
V
E
A
S
N
--------
E
R
-
E
--------------
F
G
Y
A
Q
-
V
E
V
-------------------------------
V
-
N
---
D
---
S
A
L
V
R
G
I
E
D
ALTADG
K
P
L
--
L
D
V
W
M
S
H
G
D
K
V
T
--------
A
I
P
S
D
F
I
T
V
A
S
T
-
E
S
C
P
F
A
I
M
A
N
E
E
K
R
--
F
Y
G
V
Q
F
H
P
E
V
T
H
T
R
--
Q
G
M
R
M
L
E
R
F
V
R
D
-
I
C
Q
C
E
A
L
W
T
P
A
K
I
I
D
D
A
-------------------------
17
PsiBlast_PDB
71.48
24%
-101
- C2 -
1GPM
1
GUAA_ECOLI
A:
[9-220]
--
R
I
L
I
L
D
F
G
S
Q
Y
T
Q
L
V
A
R
R
V
R
E
L
G
V
Y
C
E
L
W
A
W
D
-----
V
T
E
A
Q
I
R
-
D
F
N
PS
G
I
I
L
S
G
G
-
P
E
S
-
T
---
T
----------------
E
---
E
-
N
---
S
P
R
A
P
Q
Y
V
----
F
E
A
--
G
-
V
P
V
F
G
V
C
Y
G
M
Q
T
M
A
M
Q
L
G
G
H
V
E
A
S
N
--------
E
R
-
E
--------------
F
G
Y
A
Q
-
V
E
V
-------------------------------
V
-
N
---
D
---
S
A
L
V
R
G
I
E
D
--------
A
--
L
T
A
D
G
K
P
L
L
D
V
W
M
S
H
G
D
KVT
A
I
P
S
D
F
I
T
V
A
S
T
-
E
S
C
P
F
A
I
M
A
N
E
E
K
R
--
F
Y
G
V
Q
F
H
P
E
V
T
H
T
R
--
Q
G
M
R
M
L
E
R
F
V
---------------------------------------------
49
HHSearch
67.67
21%
-105
- C2 -
5DOT
2
CPSM_HUMAN
A:
[207-502]
-
T
K
V
V
A
V
D
C
G
--
I
K
N
N
V
I
R
L
L
V
K
R
G
A
E
V
H
L
V
P
W
N
-
H
D
F
------
T
K
M
E
Y
D
--
G
I
L
I
A
G
G
-
P
G
N
-
P
---
A
----------------
L
---
A
-
E
---
P
L
I
Q
N
V
R
K
----
I
L
E
SD
R
K
E
P
L
F
G
I
S
T
G
N
L
I
T
G
L
A
A
G
A
K
T
Y
K
M
S
--------
M
A
-
N
--------------
R
G
Q
N
Q
-
P
V
L
-------------------------------
N
-
I
---
T
---
N
------
K
Q
--------
A
--
F
I
T
A
Q
N
H
G
Y
A
L
D
N
-------
T
L
P
A
G
W
K
P
L
F
V
N
V
N
D
Q
T
N
E
G
I
M
H
E
S
K
P
--
F
F
A
V
Q
F
H
P
E
V
T
P
G
P
I-
D
T
E
Y
L
F
D
S
F
F
-
S
-
L
I
K
K
G
K
A
T
T
I
T
S
V
L
P
---------------------------