@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2626c: (2016-05-12 )
MTTARDIMNAGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIYYVDANASIQEMLNVMEEHQVRRVPVISEHRLVGIVTEADIARHLPEHAIVQFVKAICSPMALAS
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------.........10--...------......20........30----.........40.-.--......50........60-----------------------.----------------------..----------..------------------...70.....---------------...80........90........100...-.-..-.110.......120.......130.......140.--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------MT
T
A
R
D
I
M
N
A---G
V
T
------
C
VGEH
E
T
L
T
A
A
A
Q
Y
M
R
E-----HDIGALPICGDD-
D
--
R
L
H
GMLTD
R
D
I
V
I
K
G
L
AA-----------------------G----------------------LD----------PN------------------TA
T
A
G
ELAR
D
---------------
S
I
Y
Y
VDANA
S
I
Q
E
M
L
N
V
M
E
E
HQVRRVPVI-S-EH-
R
L
V
G
I
V
T
E
A
D
I
A
R
HL
P
E
H
A
I
V
Q
F
V
K
A
I
C
S
P
MALAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
96.39
100%
-129
- C1 -
1XKF
1
HRP1_MYCTU
B:
[7-129]
----------------------------------------------------------------------------------------------------------------------------
M
T
T
A
R
D
I
M
N
A
---
G
V
T
------
C
V
G
E
H
E
T
L
T
A
A
A
Q
Y
M
R
E
-----
H
D
I
G
A
L
P
I
C
G
D
D
-
D
--
R
L
H
G
M
L
T
D
R
D
I
V
I
K
G
L
A
A
-----------------------
G
----------------------
L
D
----------
P
N
------------------
T
A
T
A
G
E
L
A
R
D
---------------
S
I
Y
Y
V
D
A
N
A
S
I
Q
E
M
L
N
V
M
E
E
H
Q
V
R
R
V
P
V
I
-
S
-
E
H
-
R
L
V
G
I
V
T
E
A
D
I
A
R
H
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.91
100%
-138
- C1 -
1XKF
2
HRP1_MYCTU
A:
[8-130]
-----------------------------------------------------------------------------------------------------------------------------
T
T
A
R
D
I
M
N
A
---
G
V
T
------
C
V
G
E
H
E
T
L
T
A
A
A
Q
Y
M
R
E
-----
H
D
I
G
A
L
P
I
C
G
D
D
-
D
--
R
L
H
G
M
L
T
D
R
D
I
V
I
K
G
L
A
A
-----------------------
G
----------------------
L
D
----------
P
N
------------------
T
A
T
A
G
E
L
A
------------------
I
Y
Y
V
D
A
N
A
S
I
Q
E
M
L
N
V
M
E
E
H
Q
V
R
R
V
P
V
I
-
S
-
E
H
-
R
L
V
G
I
V
T
E
A
D
I
A
R
H
L
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
72.72
27%
-121
- C1 -
3KPB
2
Y100_METJA
A:
[2-119]
------------------------------------------------------------------------------------------------------------------------------
L
V
K
D
I
L
S
K
---
P
P
I
------
T
A
H
S
N
I
S
I
M
E
A
A
K
I
L
I
K
-----
H
N
I
N
H
L
P
I
V
D
E
H
-
G
--
K
L
V
G
I
I
T
S
W
D
I
-
A
K
A
L
A
Q
-----------------------
N
------------------------------------------------------
K
K
T
I
E
E
I
M
T
R
---------------
N
V
I
T
A
H
E
D
E
P
V
D
H
V
A
I
K
M
S
K
Y
N
I
S
G
V
P
V
V
-
D
D
Y
R
-
R
V
V
G
I
V
T
S
E
D
I
S
R
L
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
71.39
26%
-132
- C1 -
2YVY
1
MGTE_THET8
A:
[140-251]
----------------------------------------------------------------------------------------------------------------------------------
L
M
T
P
---
E
Y
V
------
A
V
R
E
G
M
T
V
E
E
V
L
R
F
L
R
R
A
APDA
E
T
I
Y
Y
I
Y
V
V
D
E
K
-
G
--
R
L
K
G
V
L
S
L
R
D
L
I
V
A
---------------------------------------------------
D
----------
P
R
------------------
T
R
V
A
-
E
I
M
N
P
---------------
K
V
V
Y
V
R
T
D
T
D
Q
E
E
V
A
R
L
M
A
D
Y
D
F
T
V
L
P
V
V
-
D
-
E
E
G
R
L
V
G
I
V
T
V
D
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
71.12
23%
-125
- C1 -
2YVX
5
MGTE_THET8
A:
[30-471]
VSLQEALQEGDTR
A
L
R
E
V
L
EEIH
P
Q
D
L
L
A
L
WDELKGE
H
R
Y
V
V
L
T
L
LP
K
A
K
A
A
E
V
L
S
H
LS
P
E
E
Q
A
E
Y
L
K
T
LPPWR
L
R
E
I
L
E
ELS
L
D
D
L
A
D
A
L
Q
A
V
R
K
E
D
P
A
Y
F
Q
R
L
K
D
L
LD
P
R
T
R
A
E
V
E
A
L
A
R
YE
E
D
E
A
G
G
L
M
T
P
---
E
Y
V
------
A
V
R
E
G
M
T
V
E
E
V
L
R
F
L
R
R
AAPDA
E
T
I
Y
Y
I
Y
V
V
D
E
K
-
G
--
R
L
K
G
V
L
S
L
R
D
L
I
----------------------------------------------------
V
A
----------
D
P
------------------
R
T
R
V
A
E
I
M
N
P
---------------
K
V
V
Y
V
R
T
D
T
D
Q
E
E
V
A
R
L
M
A
D
Y
D
F
T
V
L
P
V
V
D
E
-
E
G
-
R
L
V
G
I
V
T
V
D
D
V
L
D
V
L
E
A
E
A
T
E
D
I
H
K
L
G
A
V
D
V
P
D
L
V
Y
SEAG
P
V
A
L
W
L
A
R
V
R
W
L
V
I
L
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
V
T
ALAFYVP
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
T
L
I
I
R
A
L
A
T
RDLDLRD
W
R
R
V
F
L
K
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
L
V
G
K
VYWDGHPLLLPVV
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
R
R
L
GVDPALVS
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
L
E
46
HHSearch
70.89
29%
-108
- C1 -
4ESY
3
?
A:
[19-163]
------------------------------------------------------------------------------------------------------------------------------
P
I
R
D
I
L
T
S
---
P
V
V
------
T
V
R
E
D
D
T
L
D
A
V
A
K
T
M
L
E
-----
H
Q
I
G
C
A
P
V
V
D
Q
N
-
G
--
H
L
V
G
I
I
T
E
S
D
F
-
L
R
G
S
I
P
-----------------------
F
WIYEA
S
E
I
L
S
R
A
I
P
A
P
E
V
E
H
L
F
E
T
----------
G
R
------------------
K
L
T
A
S
A
V
M
T
Q
---------------
P
V
V
T
A
A
P
E
D
S
V
G
S
I
A
D
Q
M
R
R
H
G
I
H
R
I
P
V
V
-
Q
-
D
G
-
V
P
V
G
I
V
T
R
R
D
L
L
K
L
L
L
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
70.79
25%
-129
- C1 -
2QH1
-
?
A:
[28-150]
----------------------------------------------------------------------------------------------------------------------------------
I
M
N
S
---
N
F
K
------
T
V
N
W
N
T
T
V
F
D
A
V
K
I
M
N
E
-----
N
H
L
Y
G
L
V
V
K
D
D
N
-
G
--
N
D
V
G
L
L
S
E
R
S
I
I
K
R
F
I
P
R
-----------------------
N
----------------------
K
K
----------
P
D
------------------
E
V
P
I
R
L
V
M
R
K
---------------
P
I
P
K
V
K
S
D
Y
D
V
K
D
V
A
A
Y
L
S
E
N
G
L
E
R
C
A
V
V
-
D
-
D
P
G
R
V
V
G
I
V
T
L
T
D
L
S
R
Y
L
S
R
A
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
70.03
25%
-128
- C1 -
1PVM
-
?
A:
[14-136]
----------------------------------------------------------------------------------------------------------------------------------
I
M
N
S
---
N
F
K
------
T
V
N
W
N
T
T
V
F
D
A
V
K
I
M
N
E
-----
N
H
L
Y
G
L
V
V
K
D
D
N
-
G
--
N
D
V
G
L
L
S
E
R
S
I
I
K
R
F
I
P
R
-----------------------
N
----------------------
K
K
----------
P
D
------------------
E
V
P
I
R
L
V
M
R
K
---------------
P
I
P
K
V
K
S
D
Y
D
V
K
D
V
A
A
Y
L
S
E
N
G
L
E
R
C
A
V
V
-
D
-
D
P
G
R
V
V
G
I
V
T
L
T
D
L
S
R
Y
L
S
R
A
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
69.65
26%
-132
- C1 -
2ZY9
3
MGTE_THET8
A:
[160-271]
----------------------------------------------------------------------------------------------------------------------------------
L
M
T
P
---
E
Y
V
------
A
V
R
E
G
M
T
V
E
E
V
L
R
F
L
R
R
A
APDA
E
T
I
Y
Y
I
Y
V
V
D
E
K
-
G
--
R
L
K
G
V
L
S
L
R
D
L
I
V
A
---------------------------------------------------
D
----------
P
R
------------------
T
R
V
A
-
E
I
M
N
P
---------------
K
V
V
Y
V
R
T
D
T
D
Q
E
E
V
A
R
L
M
A
D
Y
D
F
T
V
L
P
V
V
-
D
-
E
E
G
R
L
V
G
I
V
T
V
D
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
67.86
23%
-129
- C1 -
4GQW
-
CBSX1_ARATH
A:
[75-227]
-----------------------------------------------------------------------------------------------------------------------------
Y
T
V
G
E
F
M
T
K
KE-
D
L
H
------
V
V
K
P
T
T
T
V
D
E
A
L
E
L
L
V
E
-----
N
R
I
T
G
F
P
V
I
D
E
D
-
W
--
K
L
V
G
L
V
S
D
Y
D
L
-
L
A
L
D
-------------------------------------------------
T
W
K
T
F
N
A
V
Q
K
L--------------------
G
K
L
V
G
D
L
M
T
P
---------------
A
P
L
V
V
E
E
K
T
N
L
E
D
A
A
K
I
L
L
E
T
K
Y
R
R
L
P
V
V
-
D
S
D
G
-
K
L
V
G
I
I
T
R
G
N
V
V
R
A
A
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
67.49
24%
-121
* C1 *
2RC3
12
?
A:
[6-131]
-----------------------------------------------------------------------------------------------------------------------------
K
T
V
K
H
L
L
Q
E
K
GH
T
V
V
------
A
I
G
P
D
D
S
V
F
N
A
M
Q
K
M
A
A
-----
D
N
I
G
A
L
L
V
M
K
-
D
-
E
--
K
L
V
G
I
L
T
E
R
D
F
-
S
R
K
S
Y
L
L----------------------
D
----------------------
K
P
----------
V
K
------------------
D
T
Q
V
K
E
I
M
T
R
---------------
Q
V
A
Y
V
D
L
N
N
T
N
E
D
C
M
A
L
I
T
E
M
R
V
R
H
L
P
V
L
-
D
-
D
G
-
K
V
I
G
L
L
S
I
G
D
L
V
K
D
A
I
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
67.25
26%
-116
- C1 -
2RC3
12
?
A:
[19-127]
------------------------------------------------------------------------------------------------------------------------------------------
V
V
------
A
I
G
P
D
D
S
V
F
N
A
M
Q
K
M
A
A
-----
D
N
I
G
A
L
L
V
M
K
D
E
----
K
L
V
G
I
L
T
E
R
D
F
S
R
K
S
Y
L
L
-----------------------
D
----------------------
K
P
----------
V
K
------------------
D
T
Q
V
K
E
I
M
T
R
---------------
Q
V
A
Y
V
D
L
N
N
T
N
E
D
C
M
A
L
I
T
E
M
R
V
R
H
L
P
V
L
-
D
-
D
G
-
K
V
I
G
L
L
S
I
G
D
L
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
67.23
26%
-126
- C1 -
1PVM
-
?
A:
[9-134]
-----------------------------------------------------------------------------------------------------------------------------
M
R
V
E
K
I
M
N
S
---
N
F
K
------
T
V
N
W
N
T
T
V
F
D
A
V
K
I
M
N
E
-----
N
H
L
Y
G
L
V
V
K
D
D
N
-
G
--
N
D
V
G
L
L
S
E
R
S
I
-
I
K
R
F
I
P
R----------------------
N
----------------------
K
K
----------
P
D
------------------
E
V
P
I
R
L
V
M
R
K
---------------
P
I
P
K
V
K
S
D
Y
D
V
K
D
V
A
A
Y
L
S
E
N
G
L
E
R
C
A
V
V
-
D
D
P
G
-
R
V
V
G
I
V
T
L
T
D
L
S
R
Y
L
S
R
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
66.65
20%
-130
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
-----------------------------------------------------------------------------------------------------------------------------
Q
R
V
R
D
I
M
I
P
RS-
Q
M
I
------
T
L
K
R
N
Q
T
L
D
E
C
L
D
V
I
I
E
-----
S
A
H
S
R
F
P
V
I
S
E
D
K
D
--
H
I
E
G
I
L
M
A
K
D
L
-
L
P
F
M
R
S
-----------------------
D
----------------------
A
------------
E
------------------
A
F
S
M
D
K
V
L
R
T
----------------
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
-
D
E
F
G
-
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
Fugue
66.40
18%
-128
- C1 -
2D4Z
-
CICH_TORMA
A:
[527-770]
-------------------------------------------------------------------------------------------------------------------L
S
W
S
S
A
NKY
N
I
Q
V
G
D
I
M
V
R
---
D
V
T
------
S
I
A
S
T
S
T
Y
G
D
L
L
H
V
L
R
Q
-----
T
K
L
K
F
F
P
F
V
D
T
P
-
D
TN
T
L
L
G
S
I
D
R
T
E
V
E
G
L
L
Q
R
R
-----------------------
I
----------------------
S
A
----------
Y
R
RQP
A
A
A
A
E
ADEEFEEMLT
L
E
E
I
Y
R
W
E
Q
R
EKNVVVNFET
C
R
I
D
Q
S
P
F
Q
L
V
E
G
T
S
L
Q
K
T
H
T
L
F
S
L
L
G
L
D
R
A
Y
V
T
-
S
-
M
G
-
K
L
V
G
V
V
A
L
A
E
I
Q
A
A
I
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
66.23
21%
-119
- C1 -
1PVM
1
?
A:
[7-184]
---------------------------------------------------------------------------------------------------------------------------M
F
M
R
V
E
K
I
M
N
S
---
N
F
K
------
T
V
N
W
N
T
T
V
F
D
A
V
K
I
M
N
E
-----
N
H
L
Y
G
L
V
V
K
D
D
N
-
G
--
N
D
V
G
L
L
S
E
R
S
I
I
K
R
F
I
P
R
-----------------------
N
----------------------
K
K
----------
P
D
------------------
E
V
P
I
R
L
V
M
R
K
---------------
P
I
P
K
V
K
S
D
Y
D
V
K
D
V
A
A
Y
L
S
E
N
G
L
E
R
C
A
V
V
D
D
-
P
G
-
R
V
V
G
I
V
T
L
T
D
L
S
R
Y
L
S
R
A
S
I
T
D
I
L
L
S
H
R
T
K
D
Y
Q
H
L
CPKCGV
G
V
L
E
P
V
Y
N
EKGEIK
V
F
R
C
SNPACDYEE-----------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
65.95
26%
-130
- C1 -
2YVX
5
MGTE_THET8
A:
[160-271]
----------------------------------------------------------------------------------------------------------------------------------
L
M
T
P
---
E
Y
V
------
A
V
R
E
G
M
T
V
E
E
V
L
R
F
L
R
R
AAPDA
E
T
I
Y
Y
I
Y
V
V
D
E
K
-
G
--
R
L
K
G
V
L
S
L
R
D
L
I
V
A
---------------------------------------------------
D
----------
P
R
------------------
T
R
V
A
-
E
I
M
N
P
---------------
K
V
V
Y
V
R
T
D
T
D
Q
E
E
V
A
R
L
M
A
D
Y
D
F
T
V
L
P
V
V
-
D
-
E
E
G
R
L
V
G
I
V
T
V
D
D
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
65.84
20%
-126
- C1 -
2J9L
4
CLCN5_HUMAN
A:
[9-182]
---------------------------------------------------------------------------------------------------------------------------H
K
T
L
A
M
D
V
M
K
P
---
R
R
N
DPLLTV
L
T
Q
D
S
M
T
V
E
D
V
E
T
I
I
S
E
-----
T
T
Y
S
G
F
P
V
V
V
S
R
-
E
SQ
R
L
V
G
F
V
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
QDGVVST
S
I
I
Y
FTEHSPPLP
P
----------------------
Y
T
----------
P
P
------------------
T
L
K
L
R
N
I
L
D
L
---------------
S
P
F
T
V
T
D
L
T
P
M
E
I
V
V
D
I
F
R
K
L
G
L
R
Q
C
L
V
T
-
H
-
N
G
-
R
L
L
G
I
I
T
K
K
D
V
L
K
H
I
A
Q
M
A
N
F
N
------
E
F
L
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
65.78
23%
-112
- C1 -
4O9K
2
?
A:
[6-128]
-----------------------------------------------------------------------------------------------------------------------------
T
F
V
R
D
I
M
H
T
GD-
D
T
P
------
V
I
G
L
E
A
S
V
R
D
A
L
L
E
M
T
A
-----
K
K
L
G
M
T
A
I
V
D
G
A
-
G
--
T
I
Q
G
V
F
T
D
G
D
L
-
R
R
L
L
E
K
-----------------------
A
----------------------
Q
D
----------
I
H
------------------
A
T
P
I
T
A
V
M
T
R
---------------
S
C
V
T
V
E
G
S
L
L
A
A
E
A
V
R
I
M
E
Q
K
R
I
N
A
L
P
V
V
-
E
-
N
G
-
R
L
I
G
A
I
N
M
H
D
L
L
R
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
65.31
27%
-126
- C1 -
3KPD
2
Y100_METJA
A:
[1-116]
-----------------------------------------------------------------------------------------------------------------------------
T
L
V
K
D
I
L
S
K
---
P
P
I
------
T
A
H
S
N
I
S
I
M
E
A
A
K
I
L
I
K
-----
H
N
I
N
H
L
P
I
V
D
E
H
-
G
--
K
L
V
G
I
I
T
S
W
D
I
-----
A
K
-----------------------
A
----------------------
L
A
----------
Q
N
------------------
K
K
T
I
E
E
I
M
T
R
---------------
N
V
I
T
A
H
E
D
E
P
V
D
H
V
A
I
K
M
S
K
Y
N
I
S
G
V
P
V
V
-
D
-
D
Y
R
R
V
V
G
I
V
T
S
E
D
I
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------