@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0094: (2015-12-21 )
MTLYRLHEADLEIPDAWQDQSINIFKLPASGPAREASFVISRDASQGDAPFADYVARQLENAEKQLPGFKLHKRWDINIHGHAAVLLDYQWQREGRDLMLRQVFIERRPAVLITTLTTTPADLPHHEPAWKQAMQTLVPRPTPS
Atome Classification :
(20 SA)
------------------.....--....10..---...---..-.20--..----.--------.-....---.--30........40.....---------------------...50...------.....60------------..-...---.---...70........80.....---------...90...---.-----------------....100.......------.----.110...-----.....120--------....-..-.130..--.....140..---------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------M
T
L
Y
R
--
L
HEADLEI---PDA---WQ-DQ---S
I
----
N
--------
I
-
F
KLP---A--SGPAR
E
A
S
F
V
I
SRDASQ---------------------GDA
P
F
A
D
Y
------
V
A
R
Q
L
E
-------------
N
A
-
E
K
Q---L---PG
F
K
L
H
K
R
W
D
I
N
I
HG
H
A
A
V
L
---------
L
D
Y
Q
WQRE---
G
-----------------
R
D
L
M
L
--
R
Q
V
F
I
ER------R----P
A
-
V
L
I
T
-----
T
LTTTPAD--------LPHH-
E
P
-
A
W
K
Q
A
M
--
Q
T
LVPRPTPS---------------------------------------------------------------------------------
20
Fugue
100.00
100%
-121
- C5 -
1TU1
3
?
A:
[1-144]
----------------G
H
M
T
L
Y
R
--
L
H
E
A
D
L
E
I
---
P
D
A
---
W
Q
-
D
Q
---
S
I
----
N
--------
I
-
F
K
L
P
---
A
--
S
G
P
A
R
E
A
S
F
V
I
S
R
D
A
S
Q
---------------------
G
D
A
P
F
A
D
Y
------
V
A
R
Q
L
E
-------------
N
A
-
E
K
Q
---
L
---
P
G
F
K
L
H
K
R
W
D
I
N
I
H
G
H
A
A
V
L
---------
L
D
Y
Q
W
Q
R
E
---
G
-----------------
R
D
L
M
L
--
R
Q
V
F
I
E
R
------
R
----
P
A
-
V
L
I
T
-----
T
L
T
T
T
P
A
D
--------
L
P
H
H
-
E
P
-
A
W
K
Q
A
M
--
Q
T
L
V
P
R
P
T
-----------------------------------------------------------------------------------
10
HHSearch
99.45
100%
-121
- C5 -
1TU1
3
?
A:
[3-144]
------------------
M
T
L
Y
R
--
L
H
E
A
D
L
E
I
---
P
D
A
---
W
Q
-
D
Q
---
S
I
----
N
--------
I
-
F
K
L
P
---
A
--
S
G
P
A
R
E
A
S
F
V
I
S
R
D
A
S
Q
---------------------
G
D
A
P
F
A
D
Y
------
V
A
R
Q
L
E
-------------
N
A
-
E
K
Q
---
L
---
P
G
F
K
L
H
K
R
W
D
I
N
I
H
G
H
A
A
V
L
---------
L
D
Y
Q
W
Q
R
E
---
G
-----------------
R
D
L
M
L
--
R
Q
V
F
I
E
R
------
R
----
P
A
-
V
L
I
T
-----
T
L
T
T
T
P
A
D
--------
L
P
H
H
-
E
P
-
A
W
K
Q
A
M
--
Q
T
L
V
P
R
P
T
-----------------------------------------------------------------------------------
1
PsiBlast_PDB
99.26
100%
-121
- C5 -
1TU1
3
?
A:
[3-144]
------------------
M
T
L
Y
R
--
L
H
E
A
D
L
E
I
---
P
D
A
---
W
Q
-
D
Q
---
S
I
----
N
--------
I
-
F
K
L
P
---
A
--
S
G
P
A
R
E
A
S
F
V
I
S
R
D
A
S
Q
---------------------
G
D
A
P
F
A
D
Y
------
V
A
R
Q
L
E
-------------
N
A
-
E
K
Q
---
L
---
P
G
F
K
L
H
K
R
W
D
I
N
I
H
G
H
A
A
V
L
---------
L
D
Y
Q
W
Q
R
E
---
G
-----------------
R
D
L
M
L
--
R
Q
V
F
I
E
R
------
R
----
P
A
-
V
L
I
T
-----
T
L
T
T
T
P
A
D
--------
L
P
H
H
-
E
P
-
A
W
K
Q
A
M
--
Q
T
L
V
P
R
P
T
-----------------------------------------------------------------------------------
9
PsiBlast_CBE
97.89
100%
-113
- C5 -
1TU1
5
?
B:
[3-144]
------------------
M
T
L
Y
R
--
L
H
E
A
D
L
E
I
---
P
D
A
---
W
Q
-
D
Q
---
S
I
----
N
--------
I
-
F
K
L
P
---
A
--
S
G
P
A
R
E
A
S
F
V
I
S
R
D
A
S
Q
---------------------
G
D
A
P
F
A
D
Y
------
V
A
R
Q
L
E
-------------
N
A
-
E
K
Q
---
L
---
P
G
F
K
L
H
K
R
W
D
I
N
I
H
G
H
A
A
V
L
---------
L
D
Y
Q
W
Q
R
E
---
G
-----------------
R
D
L
M
L
--
R
Q
V
F
I
E
R
------
R
----
P
A
-
V
L
I
T
-----
T
L
T
T
T
P
A
D
--------
L
P
H
H
-
E
P
-
A
W
K
Q
A
M
--
Q
T
L
V
P
R
P
T
-----------------------------------------------------------------------------------
11
HHSearch
62.81
14%
-72
- C5 -
3LYD
2
?
A:
[19-161]
---------------------------
G
F
T
V
P
I
---
P
E
T
---
W
Q
-
P
D
---
P
T
----
M
--------
G
-
T
Q
F
A
A
R
P
H
TP
P
Q
-
G
F
T
P
N
I
I
G
T
V
R
R
A
A
---------------------
T
G
A
-
L
H
N
Q
------
R
T
-
E
L
D
-------------
Q
R
-
A
T
Q
---
L
---
P
D
Y
A
E
R
G
R
T
E
T
T
V
D
G
F
P
A
Y
H
---------
I
E
Y
A
Y
R
H
H
G--
T
-----------------
I
T
I
A
Q
--
M
I
T
L
V
E
V
------
S
H
PH
A
V
D
-
I
I
Q
L
-----
T
A
T
C
A
G
D
Q
--------
T
A
D
Y
-
W
D
-
T
F
R
L
M
H
--
A
D
L
T
V
Q
P
H
G
----------------------------------------------------------------------------------
14
HHSearch
55.67
7%
-76
- C5 -
1V2B
2
PSBP2_TOBAC
A:
[11-177]
--------------------
T
Y
N
--
G
D
G
F
K
L
Q
I
---
P
S
K
---
W
N
-
P
N
KEV
E
Y
PGQV
L
--------
R
-
F
E
D
N
---
F
--
D
A
---
T
S
N
V
I
V
A
I
T
P
T
D
KKSIT----------------
D
F
G
S
P
E
Q
F
------
L
S
Q
V
D
Y
-------------
L
L
----A--
V
---
A
I
A
N
V
L
E
T
S
T
A
E
V
G
G
K
Q
Y
Y
Y
---------
L
S
I
L
T
R
T
----------------------
G
G
K
H
Q
--
L
V
T
A
T
V
N
------
D
----
G
K
-
L
Y
I
C
-----
K
A
Q
A
G
D
K
R
--------
W
F
K
G
A
K
K
-
F
V
E
N
T
A
--
T
S
F
S
L
A
-------------------------------------------------------------------------------------
13
HHSearch
55.58
11%
-76
- C5 -
2LNJ
-
?
A:
[33-187]
-------------------
Q
R
Y
S
D
T
K
D
G
Y
E
F
L
Y
---
P
N
G
---
W
I
-
G
V
---
D
V
----
K
GASPGVD
V
V
-
F
R
D
L
---
I
-----
E
R
D
E
N
L
S
V
I
I
S
E
I
P
---------------------
S
D
K
T
L
T
D
L
GT
A
T
D
V
G
Y
R
F
M
K
-------------
T
V
-
N
D
A
SQG
D
---
R
Q
A
E
L
I
N
A
E
A
R
D
E
D
G
Q
V
Y
Y
T
---------
L
E
Y
R
V
L
V
G
D--
N
-----------------
V
E
R
H
D
--
L
A
S
V
T
T
N
------
R
----
G
K
-
L
I
T
F
-----
D
L
S
T
A
E
D
R
--------
W
D
T
V
-
K
S
-
L
F
D
T
V
A
--
S
S
F
H
V
Y
-------------------------------------------------------------------------------------
12
HHSearch
54.99
11%
-73
- C5 -
2XB3
5
?
A:
[10-165]
--------------------
A
Y
V
D
S
Y
D
G
Y
E
F
L
Y
---
P
R
G
---
W
V
-
Q
V
---
Q
V
----
E
D
PV-----
D
-
V
V
F
H
---
D
--
I
I
-
E
T
T
E
N
V
S
V
V
V
N
T
V
A
---------------------
S
T
K
S
L
E
E
L
GS
P
E
E
V
G
D
R
L
L
R
-------------
N
I
-
I
A
P
---
S
ESG
R
S
S
A
L
I
A
A
T
S
Q
K
A
D
D
K
T
Y
Y
I
---------
L
E
Y
A
V
T
L
P
----A----------------
Q
Q
R
H
N
--
L
S
S
I
A
V
S
------
R
----
G
K
-
V
Y
T
L
-----
S
V
S
A
P
E
E
R
--------
W
P
K
V
-
E
D
-
Q
F
K
T
I
V
--
S
S
F
T
V
Y
-------------------------------------------------------------------------------------
26
Fugue
51.07
15%
-54
- C5 -
1YAX
4
PHOQ_SALTY
A:
[1-153]
----------------MD
K
T
T
F
R
--
L
L
R
G
E
S
N
L
---
F
Y
T
L
A
K
W
E
-
N
N
---
K
I
----
S
--------
V
--
E
L
P
---
E
--
N
L
D
M
Q
S
P
T
M
T
L
I
Y
D
-
E
T
---------------------
G
K
L
L
W
T
Q
R
------
N
I
P
W
L
I
-------------
K
S
I
Q
P
E
---
W
---
L
K
T
N
G
F
H
E
I
E
T
N
V
D
A
T
S
T
L
L
SEDH
S
A
Q
E
K
L
K
E
V
R
E
D
D
---
D
-----------------
D
A
E
M
T
--
H
S
V
A
V
N
I
Y
P
A
TAR
M
----
P
Q
-
L
T
I
V
-----
V
V
D
T
I
P
I
E
--------
L
------------
K
--
R
S
Y
M
H
H
H
H
H
H
---------------------------------------------------------------------------------
22
Fugue
48.25
10%
-58
- C5 -
2EHB
-
D:
[2-127]
------------------
E
G
P
L
M
--
M
N
A
F
E
M
I
T
---
L
S
Q
---
G
L
-
N
L
---
S
-----
A
--------
L
-
F
D
R
R
---
Q
--
D
F
V
K
R
Q
T
R
F
V
S
R
R
E
-----------------------------
P
S
E
------
I
I
A
N
I
E
-------------
A
V
-
A
N
S
---
M
---
G
F
K
S
H
T
R
N
F
K
T
R
L
E
G
L
S
-----------------
S
I
K
---
A
-----------------
G
Q
L
A
V
--
V
I
E
I
Y
E
V
------
A
----
P
S
-
L
F
M
V
-----
D
V
R
K
A
A
G
E
--------
T
L
E
Y
-
H
K
-
F
Y
K
K
L
C
--
S
K
L
E
N
I
I
W
R
----------------------------------------------------------------------------------
24
Fugue
45.55
11%
-32
* C5 *
4OL4
-
PR28_MYCTU
A:
[76-252]
P
V
T
P
A
ISGT
L
R
D
H
L
R
E
K
G
V
K
L
E
A
--
Q
R
P
H
G
F
K
A
---
L
D
I
---
T
L
-
P
M
---
P
P
----
R
--------
W
-
T
Q
V
P
---
D
--
P
N
V
P
D
A
F
V
V
I
A
D
R
L
G
N
S
---------------------
V
Y
T
S
N
A
Q
L
------
V
V
Y
R
L
I
G
DFD
P
A
E
A
I
T
HGY
I
D
-
S
Q
K
---
L
---
L
A
W
Q
T
T
N
A
S
M
A
N
F
D
G
F
P
S
S
I
---------
I
E
G
T
Y
R
E
N
---
D
-----------------
M
T
L
N
T
S
R
R
H
V
I
A
T
S
------
G
----
A
D
-
K
Y
L
V
-----
S
L
S
V
T
T
A
L
--------
S
Q
A
V
-
T
D
-
G
P
A
T
D
A
--
I
V
N
G
F
Q
V
V
A
H
---------------------------------------------------------------------------------
29
Fugue
42.87
21%
-40
- C5 -
3WTT
2
RUNX1_MOUSE
A:
[1-119]
------------------
G
E
L
V
R
--
T
D
S
P
N
F
L
C
S
V
L
P
T
H
---
W
R
C
N
K
---
T
L
----
P
--------
I
A
F
K
V
V
---
A
--
K
G
D
V
P
D
G
T
L
V
T
V
M
A
G
N
D
---------------------
E
N
Y
S
A
------------
E
L
R
-------------
N
A
-
T
A
A
---
M
---
K
N
-------------
Q
V
A
R
F
--------------------------------------
N
D
L
R
F
--
V
G
R
S
G
R
G
------
K
----
S
F
-
T
L
T
I
-----
T
V
F
T
N
P
P
Q
--------
V
A
T
Y
-
H
R
-
A
I
K
I
T
V
--
D
G
--
P
R
E
P
R
R
---------------------------------------------------------------------------------
25
Fugue
38.77
12%
-45
- C5 -
1ZHH
1
LUXQ_VIBHA
B:
[15-235]
--------RT
K
Q
Q
T
S
A
L
I
H
N
I
F
D
--
S
H
F
A
A
I
Q
I
---
H
H
D
---
S
N
-
S
K
---
S
E
----
V
--------
I
-
R
D
F
Y
---
T
--
D
R
D
T
D
V
L
N
F
F
F
L
S
I
D
Q
S
DPSHTPE
F
R
F
L
T
D
HKGIIWDD
G
N
A
H
F
Y
G
V
------
N
D
L
I
L
D
-------------
S
L
-
A
N
R
---
V
---
S
F
S
N
N
W
Y
Y
I
N
V
M
T
S
I
G
S
R
H
M
---------
L
V
R
R
V
P
I
L
---
D
PSTGEVL
G
F
S
F
N
A
V
V
LD
N
N
F
A
L
--
M
E
K
L
K
S
E
S
NV---
D
----
N
V
-
V
L
V
A
-----
N
S
V
P
L
A
N
S
--------
L
I
G
D
-
E
P
Y
N
V
A
D
V
L
--
V
I
E
T
P
I
V
V
N
A
VTTE
L
C
L
L
T
V
QD---------------------------------------------------------------------
27
Fugue
38.20
17%
-78
- C4 -
3FMG
2
VP7_ROTRH
A:
[28-262]
---------------T
S
T
L
C
L
Y
Y
--
P
T
E
A
A
T
E
I
---
N
D
N
---
S
W
-
K
D
---
T
L
----
S
--------
Q
-
L
F
L
T
---
K
--
G
W
P
T
G
S
V
Y
F
K
E
Y
T
D
----------------------------
I
A
S
F
------
S
V
D
P
Q
L
-------------
Y
C
-
D
Y
N
---
V
---
V
L
M
K
Y
D
A
T
L
Q
L
D
M
S
E
L
A
D
L
I
---------
L
-
N
E
W
L
C
N
---
P
-----------------
M
D
I
T
L
--
Y
Y
Y
Q
Q
T
D
------
E
----
A
N
-
K
W
I
S
M
GS
S
C
T
I
K
V
C
P
L
N
TQTLGIGC
L
T
T
D
-
T
A
-
T
F
E
E
V
A
TA
E
K
L
V
I
T
D
V
V
D
GVNHKLDVTTAT
C
T
I
R
N
C
K
K
LGPREN
V
A
V
I
Q
V
G
GSDVLDITADPT
T
A
P
Q
T
ER
M
M
R
I
N
W
K
K
W
W
Q
V
F
Y
T
V
V
D
Y
V
N
Q
I
I
Q
A
M
S
K
7
PsiBlast_PDB
38.20
28%
-87
- C6 -
1P59
3
?
A:
[67-138]
-------------------------------------------------------------------------------------------------------------------------
D
Y
------
I
A
V
P
L
E
-------------
E
L
-
E
Q
D
---
I
---
R
S
I
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
---------
I
D
-
K
Y
N
G
E
VPR
D
-----------------
R
D
E
L
M
--
K
L
P
G
V
G
R
------
K
----
T
A
N
V
V
V
S
-----
T
A
F
G
V
P
A
I
--------
A
V
D
T
-
H
V
-
E
R
V
S
K
R
--
L
G
F
C
R
W
D
D
S
V
---------------------------------------------------------------------------------
23
Fugue
37.04
14%
-8
- C3 -
3P8C
1
ABI2_HUMAN
F:
[1-156]
----------------AM
A
E
L
Q
M
--
L
L
E
E
--
E
I
---
P
G
G
---
R
R
-
A
L
---
F
D
----
S
--------
Y
-
T
N
L
E
---
R
--
V
A
D
Y
C
E
N
N
Y
I
Q
S
A
D
K
Q
R
---------------------
A
L
E
E
T
K
A
Y
------
T
T
Q
S
L
A
-------------
S
V
-
A
Y
L
---
I
---
N
T
L
A
N
N
V
L
Q
M
L
D
I
Q
A
S
Q
L
R
R
---------
M
E
S
S
I
N
H
I
---
S
-----------------
Q
T
V
D
I
--
H
K
E
K
V
A
R
------
R
----
E
I
-
G
I
L
T
-----
T
N
K
N
T
S
R
T
--------
H
K
I
I
-
A
P
-
A
N
L
E
R
P
--
V
R
Y
I
R
K
P
I
D
Y
TILDDIGHGVKV---------------------------------------------------------------------
3
PsiBlast_PDB
36.42
26%
-56
- C6 -
4R86
-
?
A:
[79-149]
----------------------
Q
--
L
Q
S
A
M
R
K
L
---
P
Q
A
---
V
Q
-
D
Q
---
G
V
----
T
--------
V
-
R
K
T
G
---
D
--
T
N
I
L
T
I
A
--
F
V
S
T
D
G
S
M
---------------------
D
K
Q
D
I
A
D
Y
------
V
A
S
N
I
Q
-------------
D
------------
P
L
S
R
V
N
G
V
G
D
I
D
A
Y
G
S
Q
Y
S
M
---------
R
I
W
L
D
P
A
K
---
L
-----------------
N
S
F
Q
M
--
T
T
K
D
V
T
D
------
A
----
I
E
-
S
Q
N
A
-----
Q
I
A
V
G
Q
L
G
--------
G
Q
A
L
-
N
A
-
T
I
N
A
Q
S
--
L
L
Q
T
P
Q
Q
F
R
D
---------------------------------------------------------------------------------
2
PsiBlast_PDB
35.62
28%
-55
- C6 -
4QJY
2
?
A:
[168-221]
---------------------------------------------------------------------------------------------------------------------
C
K
Y
A
D
Y
------
I
G
T
V
F
G
-------------
R
G
-
E
G
Q
---
I
---
P
G
Y
D
G
H
Q
E
I
E
L
------
A
L
L
---------
K
L
Y
E
V
T
G
N
---
E
-----------------
N
Y
L
K
L
--
S
Q
Y
F
I
D
Q
------
R
----
G
Q
-
Q
P
Y
Y
-----
F
D
Q
E
K
E
A
R
--------
G
E
T
E
-
P
F
-
W
Y
D
G
G
Y
--
R
Y
H
Q
A
H
I
P
V
R
---------------------------------------------------------------------------------
6
PsiBlast_PDB
35.28
29%
-60
- C6 -
4QK0
-
?
A:
[170-221]
-----------------------------------------------------------------------------------------------------------------------
Y
A
D
Y
------
I
G
T
V
F
G
-------------
R
G
-
E
G
Q
---
I
---
P
G
Y
D
G
H
Q
E
I
E
L
------
A
L
L
---------
K
L
Y
E
V
T
G
N
---
E
-----------------
N
Y
L
K
L
--
S
Q
Y
F
I
D
Q
------
R
----
G
Q
-
Q
P
Y
Y
-----
F
D
Q
E
K
E
A
R
--------
G
E
T
E
-
P
F
-
W
Y
D
G
G
Y
--
R
Y
H
Q
A
H
I
P
V
R
---------------------------------------------------------------------------------
8
PsiBlast_PDB
35.15
37%
-26
- C6 -
1YR2
1
?
A:
[648-682]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
-
I
L
V
T
-----
T
A
D
T
D
D
R
V
--------
V
P
G
H
-
S
F
-
K
Y
T
A
A
L
--
Q
T
A
A
I
G
P
K
P
----------------------------------------------------------------------------------