@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0717: (2015-12-04 )
MAIERTLSILKPDTVKNNIIGNINSYIEKSGLRIIAQKMMLLTKKQAELFYAIHKDRPFFGGLVEFMTSGPVIVQVLVGENAISKYRQIMGATDPKQADKGTIRGDFADDVNENRVHGSDSLENAHKEIAFFFAECELV
Atome Classification :
(73 SA)
.........10........20........30........40-........50........60........70........80........90......-..100.......---110.---......120.......130.......-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
I
E
R
T
L
S
ILKPDTVKNNIIGN
I
N
S
Y
I
E
K
S
G
L
R
I
I
A
Q
K
M
M
L
-
L
T
K
KQ
A
E
L
F
Y
A
IHKDRPFF
G
G
L
V
E
F
MTSG
P
V
I
V
Q
V
LVG
E
N
A
I
S
K
Y
R
Q
I
MGATDPKQ-ADKGTIRGDFAD---DVNE---NRVHGS
D
S
L
E
N
A
H
K
E
I
A
F
F
F
A
ECELV-----
1
PsiBlast_PDB
94.67
63%
-88
- C8 -
3VGU
-
?
A:
[2-139]
-
A
T
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
E
I
E
S
R
F
E
K
A
G
L
K
I
V
A
A
K
M
L
Q
-
L
S
Q
E
Q
A
E
G
F
Y
A
E
H
K
E
R
P
F
F
G
D
L
V
G
F
M
T
S
G
P
V
V
V
Q
V
L
E
G
E
N
A
I
A
A
N
R
D
L
M
G
A
T
N
P
K
E
-
A
E
A
G
T
I
R
A
D
Y
A
Q
---
S
I
D
A
---
N
A
V
H
G
S
D
S
P
E
S
A
A
R
E
I
A
Y
F
F
A
E
S
E
I
C
-----
25
PsiBlast_CBE
94.18
59%
-84
- C8 -
4S0M
1
?
D:
[1-139]
M
A
I
E
R
T
L
S
I
V
K
P
D
A
V
S
K
N
H
I
G
E
I
F
A
R
F
E
K
A
G
L
K
I
V
A
T
K
M
K
H
-
L
S
Q
A
D
A
E
G
F
Y
A
E
H
K
E
R
G
F
F
G
D
L
V
A
F
M
T
S
G
P
V
V
V
S
V
L
E
G
E
N
A
V
L
A
H
R
E
I
L
G
A
T
N
P
K
E
-
A
A
P
G
T
I
R
A
D
F
A
V
---
S
I
D
E
---
N
A
A
H
G
S
D
S
V
A
S
A
E
R
E
I
A
Y
F
F
A
D
N
E
I
C
-----
8
PsiBlast_PDB
94.12
59%
-87
- C8 -
4S0M
-
?
A:
[1-139]
M
A
I
E
R
T
L
S
I
V
K
P
D
A
V
S
K
N
H
I
G
E
I
F
A
R
F
E
K
A
G
L
K
I
V
A
T
K
M
K
H
-
L
S
Q
A
D
A
E
G
F
Y
A
E
H
K
E
R
G
F
F
G
D
L
V
A
F
M
T
S
G
P
V
V
V
S
V
L
E
G
E
N
A
V
L
A
H
R
E
I
L
G
A
T
N
P
K
E
-
A
A
P
G
T
I
R
A
D
F
A
V
---
S
I
D
E
---
N
A
A
H
G
S
D
S
V
A
S
A
E
R
E
I
A
Y
F
F
A
D
N
E
I
C
-----
3
PsiBlast_PDB
94.05
62%
-82
- C8 -
3VGS
-
?
A:
[2-139]
-
A
T
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
E
I
E
S
R
F
E
K
A
G
L
K
I
V
A
A
K
M
L
Q
-
L
S
Q
E
Q
A
E
G
F
Y
A
E
H
K
E
R
P
F
F
G
D
L
V
G
F
M
T
S
G
P
V
V
V
Q
V
L
E
G
E
N
A
I
A
A
N
R
D
L
M
G
A
T
N
P
K
E
-
A
E
A
G
T
I
R
A
D
Y
A
Q
---
S
I
D
A
---
N
A
V
H
G
S
D
S
P
E
S
A
A
R
E
I
A
Y
F
F
E
E
S
E
I
C
-----
6
PsiBlast_PDB
93.28
60%
-85
- C8 -
4EK2
3
NDK_BURTA
A:
[5-142]
M
A
L
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
Q
I
Y
S
R
F
E
N
A
G
L
K
I
V
A
A
R
M
A
H
-
L
S
R
A
D
A
E
K
F
Y
A
V
H
A
E
R
P
F
F
K
D
L
V
E
F
M
I
S
G
P
V
M
I
Q
V
L
E
G
E
D
A
I
L
K
N
R
D
L
M
G
A
T
D
P
K
K
-
A
E
K
G
T
I
R
A
D
F
A
D
---
S
I
D
A
---
N
A
V
H
G
S
D
A
P
E
T
A
R
V
E
I
A
F
F
F
P
E
M
N
V
Y
-----
9
PsiBlast_PDB
92.99
59%
-84
- C8 -
4W98
-
NDK_ACIBS
A:
[3-141]
M
A
I
E
R
T
L
S
I
V
K
P
D
A
V
S
K
N
H
I
G
E
I
F
A
R
F
E
K
A
G
L
K
I
V
A
T
K
M
K
H
-
L
S
Q
A
D
A
E
G
F
Y
A
E
H
K
E
R
G
F
F
G
D
L
V
A
F
M
T
S
G
P
V
V
V
S
V
L
E
G
E
N
A
V
L
A
H
R
E
I
L
G
A
T
N
P
K
E
-
A
A
P
G
T
I
R
A
D
F
A
V
---
S
I
D
E
---
N
A
A
H
G
S
D
S
V
A
S
A
E
R
E
I
A
Y
F
F
A
D
N
E
I
C
-----
24
PsiBlast_CBE
92.85
59%
-87
- C8 -
4S0M
1
?
G:
[1-139]
M
A
I
E
R
T
L
S
I
V
K
P
D
A
V
S
K
N
H
I
G
E
I
F
A
R
F
E
K
A
G
L
K
I
V
A
T
K
M
K
H
-
L
S
Q
A
D
A
E
G
F
Y
A
E
H
K
E
R
G
F
F
G
D
L
V
A
F
M
T
S
G
P
V
V
V
S
V
L
E
G
E
N
A
V
L
A
H
R
E
I
L
G
A
T
N
P
K
E
-
A
A
P
G
T
I
R
A
D
F
A
V
---
S
I
D
E
---
N
A
A
H
G
S
D
S
V
A
S
A
E
R
E
I
A
Y
F
F
A
D
N
E
I
C
-----
4
PsiBlast_PDB
92.67
62%
-89
- C8 -
3VGT
-
?
A:
[2-139]
-
A
T
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
E
I
E
S
R
F
E
K
A
G
L
K
I
V
A
A
K
M
L
Q
-
L
S
Q
E
Q
A
E
G
F
Y
A
E
H
K
E
R
P
F
F
G
D
L
V
G
F
M
T
S
G
P
V
V
V
Q
V
L
E
G
E
N
A
I
A
A
N
R
D
L
M
G
A
T
N
P
K
E
-
A
E
A
G
T
I
R
A
D
Y
A
Q
---
S
I
D
A
---
N
A
V
H
G
S
D
S
P
E
S
A
A
R
E
I
A
Y
F
F
E
E
S
E
I
C
-----
2
PsiBlast_PDB
92.16
63%
-84
- C8 -
3VGV
-
?
A:
[2-139]
-
A
T
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
E
I
E
S
R
F
E
K
A
G
L
K
I
V
A
A
K
M
L
Q
-
L
S
Q
E
Q
A
E
G
F
Y
A
E
H
----
F
F
G
D
L
V
G
F
M
T
S
G
P
V
V
V
Q
V
L
E
G
E
N
A
I
A
A
N
R
D
L
M
G
A
T
N
P
K
E
-
A
E
A
G
T
I
R
A
D
Y
A
Q
---
S
I
D
A
---
N
A
V
H
G
S
D
S
P
E
S
A
A
R
E
I
A
Y
F
F
A
E
S
E
I
C
-----
10
PsiBlast_PDB
91.60
59%
-88
- C8 -
4WBF
-
NDK_ACIBS
A:
[3-140]
M
A
I
E
R
T
L
S
I
V
K
P
D
A
V
S
K
N
H
I
G
E
I
F
A
R
F
E
K
A
G
L
K
I
V
A
T
K
M
K
H
-
L
S
Q
A
D
A
E
G
F
Y
A
E
H
K
E
R
G
F
F
G
D
L
V
A
F
M
T
S
G
P
V
V
V
S
V
L
E
G
E
N
A
V
L
A
H
R
E
I
L
G
A
T
N
P
K
E
-
A
A
P
G
T
I
R
A
D
F
A
V
---
S
I
D
E
---
N
A
A
H
G
S
D
S
V
A
S
A
E
R
E
I
A
Y
F
F
A
D
N
E
I
------
13
PsiBlast_PDB
91.25
58%
-82
- C8 -
2NCK
-
NDK_MYXXA
R:
[2-138]
-
A
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
-----
21
PsiBlast_CBE
91.15
60%
-84
- C8 -
4HR2
1
NDK_BURTA
B:
[6-142]
-
A
L
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
Q
I
Y
S
R
F
E
N
A
G
L
K
I
V
A
A
R
M
A
H
-
L
S
R
A
D
A
E
K
F
Y
A
V
H
A
E
R
P
F
F
K
D
L
V
E
F
M
I
S
G
P
V
M
I
Q
V
L
E
G
E
D
A
I
L
K
N
R
D
L
M
G
A
T
D
P
K
K
-
A
E
K
G
T
I
R
A
D
F
A
D
---
S
I
D
A
---
N
A
V
H
G
S
D
A
P
E
T
A
R
V
E
I
A
F
F
F
P
E
M
N
V
Y
-----
123
Fugue
91.02
57%
-85
- C8 -
1NLK
2
NDK_MYXXA
R:
[1-143]
-
A
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
SYPYQ
35
PsiBlast_CBE
91.02
58%
-84
- C8 -
1NHK
1
NDK_MYXXA
L:
[1-137]
-
A
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
-----
22
PsiBlast_CBE
90.67
60%
-83
- C8 -
4EK2
3
NDK_BURTA
B:
[6-142]
-
A
L
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
Q
I
Y
S
R
F
E
N
A
G
L
K
I
V
A
A
R
M
A
H
-
L
S
R
A
D
A
E
K
F
Y
A
V
H
A
E
R
P
F
F
K
D
L
V
E
F
M
I
S
G
P
V
M
I
Q
V
L
E
G
E
D
A
I
L
K
N
R
D
L
M
G
A
T
D
P
K
K
-
A
E
K
G
T
I
R
A
D
F
A
D
---
S
I
D
A
---
N
A
V
H
G
S
D
A
P
E
T
A
R
V
E
I
A
F
F
F
P
E
M
N
V
Y
-----
15
PsiBlast_PDB
90.64
58%
-83
- C8 -
1NHK
1
NDK_MYXXA
R:
[1-137]
-
A
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
-----
14
PsiBlast_PDB
90.26
58%
-83
- C8 -
1NLK
2
NDK_MYXXA
R:
[1-137]
-
A
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
-----
109
HHSearch
90.14
58%
-82
- C8 -
1NHK
1
NDK_MYXXA
R:
[2-137]
--
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
-
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
---
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
-----
7
PsiBlast_PDB
89.90
60%
-85
- C8 -
4HR2
1
NDK_BURTA
A:
[5-142]
M
A
L
E
R
T
L
S
I
I
K
P
D
A
V
A
K
N
V
I
G
Q
I
Y
S
R
F
E
N
A
G
L
K
I
V
A
A
R
M
A
H
-
L
S
R
A
D
A
E
K
F
Y
A
V
H
A
E
R
P
F
F
K
D
L
V
E
F
M
I
S
G
P
V
M
I
Q
V
L
E
G
E
D
A
I
L
K
N
R
D
L
M
G
A
T
D
P
K
K
-
A
E
K
G
T
I
R
A
D
F
A
D
---
S
I
D
A
---
N
A
V
H
G
S
D
A
P
E
T
A
R
V
E
I
A
F
F
F
P
E
M
N
V
Y
-----
32
PsiBlast_CBE
89.48
55%
-87
- C8 -
2HUR
1
NDK_ECOLI
C:
[1-138]
-
A
I
E
R
T
F
S
I
I
K
P
N
A
V
A
K
N
V
I
G
N
I
F
A
R
F
E
A
A
G
F
K
I
V
G
T
K
M
L
H
-
L
T
V
E
Q
A
R
G
F
Y
A
E
H
D
G
K
P
F
F
D
G
L
V
E
F
M
T
S
G
P
I
V
V
S
V
L
E
G
E
N
A
V
Q
R
H
R
D
L
L
G
A
T
N
P
A
N
-
A
L
A
G
T
L
R
A
D
Y
A
D
---
S
L
T
E
---
N
G
T
H
G
S
D
S
V
E
S
A
A
R
E
I
A
Y
F
F
G
E
G
E
V
C
-----
19
PsiBlast_PDB
88.20
48%
-89
- C8 -
1WKK
1
NDK_THET8
A:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
-
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
E
---
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
-----
84
PsiBlast_CBE
87.53
47%
-90
- C8 -
2DXF
2
NDK_PYRHO
A:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
86
PsiBlast_CBE
87.23
47%
-89
- C8 -
2DXE
2
NDK_PYRHO
A:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
20
PsiBlast_PDB
87.19
48%
-92
- C8 -
1WKL
2
NDK_THET8
A:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
-
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
E
---
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
-----
80
PsiBlast_CBE
87.05
47%
-89
- C8 -
2DYA
3
NDK_PYRHO
A:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
79
PsiBlast_CBE
86.96
47%
-89
- C8 -
2DYA
4
NDK_PYRHO
B:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
87
PsiBlast_CBE
86.80
47%
-90
- C8 -
2DXD
2
NDK_PYRHO
B:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
48
PsiBlast_CBE
86.76
46%
-88
- C8 -
1NDC
2
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
49
PsiBlast_CBE
86.53
46%
-85
- C8 -
1KDN
2
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
88
PsiBlast_CBE
86.43
47%
-92
- C8 -
2DXD
2
NDK_PYRHO
A:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
82
PsiBlast_CBE
86.41
47%
-89
- C8 -
2DY9
3
NDK_PYRHO
A:
[8-145]
---
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
---
E
V
S
D
AIC
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
36
PsiBlast_CBE
86.39
48%
-89
- C8 -
1WKL
2
NDK_THET8
B:
[1-137]
--
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
-
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
K
D
-
A
L
P
G
T
I
R
G
D
F
A
T
---
T
I
D
E
---
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
E
E
L
L
-----
61
PsiBlast_CBE
86.20
46%
-89
- C8 -
1B99
1
NDKC_DICDI
F:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
64
PsiBlast_CBE
85.73
46%
-88
- C8 -
1B99
1
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
95
PsiBlast_CBE
85.56
43%
-90
- C8 -
3Q8Y
2
NDK_STAAC
B:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
60
PsiBlast_CBE
85.55
46%
-90
- C8 -
1BUX
1
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
55
PsiBlast_CBE
85.33
46%
-84
- C8 -
1F6T
2
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
90
PsiBlast_CBE
85.28
43%
-90
- C8 -
3Q8Y
2
NDK_STAAC
G:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
62
PsiBlast_CBE
85.25
46%
-89
- C8 -
1B99
1
NDKC_DICDI
E:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
40
PsiBlast_CBE
85.21
46%
-83
- C8 -
2BEF
2
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
53
PsiBlast_CBE
85.19
46%
-87
- C8 -
1HIY
1
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
63
PsiBlast_CBE
85.11
46%
-90
- C8 -
1B99
1
NDKC_DICDI
D:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
93
PsiBlast_CBE
85.09
43%
-88
- C8 -
3Q8Y
3
NDK_STAAC
D:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
101
PsiBlast_CBE
85.03
43%
-87
- C8 -
3Q8U
2
NDK_STAAC
E:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
46
PsiBlast_CBE
84.97
46%
-83
- C8 -
1NDP
1
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
65
PsiBlast_CBE
84.93
46%
-84
- C8 -
1B99
1
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
52
PsiBlast_CBE
84.78
46%
-91
- C8 -
1HIY
1
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
97
PsiBlast_CBE
84.70
43%
-88
- C8 -
3Q8V
2
NDK_STAAC
D:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
115
HHSearch
84.65
42%
-86
- C8 -
1ZS6
1
NDK3_HUMAN
A:
[20-156]
-
A
H
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
-
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
K
---
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
-----
51
PsiBlast_CBE
84.64
46%
-83
- C8 -
1KDN
2
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
50
PsiBlast_CBE
84.53
46%
-84
- C8 -
1KDN
2
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
122
HHSearch
84.27
47%
-88
- C8 -
2DXE
2
NDK_PYRHO
A:
[6-146]
-
E
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
-
A
A
P
G
T
I
R
G
D
F
G
L
EVS
D
A
I
C
---
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
-----
66
PsiBlast_CBE
84.13
46%
-88
- C8 -
1B99
1
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
42
PsiBlast_CBE
84.09
46%
-83
- C8 -
2BEF
2
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
100
PsiBlast_CBE
84.07
43%
-83
- C8 -
3Q8U
2
NDK_STAAC
F:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
58
PsiBlast_CBE
83.87
46%
-88
- C8 -
1BUX
1
NDKC_DICDI
C:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
41
PsiBlast_CBE
83.86
46%
-81
- C8 -
2BEF
2
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
99
PsiBlast_CBE
83.47
43%
-86
- C8 -
3Q8V
2
NDK_STAAC
A:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
47
PsiBlast_CBE
83.22
46%
-83
- C8 -
1NDP
1
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
89
PsiBlast_CBE
83.16
43%
-91
- C8 -
3Q8Y
3
NDK_STAAC
H:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
54
PsiBlast_CBE
83.10
46%
-87
- C8 -
1HIY
1
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
117
HHSearch
82.76
43%
-84
- C8 -
3Q8U
2
NDK_STAAC
A:
[1-136]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
98
PsiBlast_CBE
82.71
43%
-87
- C8 -
3Q8V
2
NDK_STAAC
B:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
39
PsiBlast_CBE
82.67
50%
-78
- C8 -
4ANE
1
NDK_MYCTU
A:
[3-133]
---
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
---
E
T
Q
F
---
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------
96
PsiBlast_CBE
82.44
43%
-90
- C8 -
3Q8Y
2
NDK_STAAC
A:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
38
PsiBlast_CBE
82.16
50%
-77
- C8 -
4ANE
1
NDK_MYCTU
D:
[3-133]
---
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
----
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
---
E
T
Q
F
---
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------
56
PsiBlast_CBE
81.96
46%
-82
- C8 -
1F6T
2
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
92
PsiBlast_CBE
81.80
43%
-89
- C8 -
3Q8Y
2
NDK_STAAC
E:
[1-137]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
-
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
---
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
-----
45
PsiBlast_CBE
81.68
46%
-86
- C8 -
1S5Z
1
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
57
PsiBlast_CBE
80.93
46%
-83
- C8 -
1F6T
2
NDKC_DICDI
A:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
59
PsiBlast_CBE
80.85
46%
-85
- C8 -
1BUX
1
NDKC_DICDI
B:
[9-144]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
-
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
---
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
-----
37
PsiBlast_CBE
80.58
50%
-75
- C8 -
4ANE
1
NDK_MYCTU
F:
[3-133]
---
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
-
V
S
A
E
L
A
S
Q
H
Y
A
E
H
--------
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
---
E
T
Q
F
---
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
A
--------
110
HHSearch
77.88
37%
-75
- C8 -
3EVO
1
NDK_MIMIV
A:
[6-138]
--
L
Q
R
T
L
V
L
I
K
P
D
A
F
E
R
S
L
V
A
E
I
M
G
R
I
E
K
K
N
F
K
I
V
S
M
K
F
W
S
K
A
P
R
N
L
I
E
Q
H
Y
K
E
H
S
E
Q
S
Y
F
N
D
N
C
D
F
M
V
S
G
P
I
I
S
I
V
Y
E
G
T
D
A
I
S
K
I
R
R
L
Q
G
N
T
N
P
L
A
-
S
A
P
G
T
I
R
G
D
L
A
N
---
D
I
R
E
---
N
L
I
H
A
S
D
S
E
D
S
A
V
D
E
I
S
I
W
F
P
----------