@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0804: (2015-12-04 )
MLNLESLPKHLAIIMDGNSRWANSQGRVKIDGYRKGSEVAYDIAKHCIALAIPYLTLYAFSMENWLRPKEETDCLFDLFYSILTDRDKVNFFHNYNIKLNFVGNLSLLPGKILNQIKESEEMTRKNDGLLLTVAVSYGAKQEIIHAVRNITRKNIDCVSEDEFEKFLYTKDLPKLDLLIRTGGEKRLSNFLLWQAAYAELYFCDTLWPDFSCQDLSKALEDYTKREKRYGR
Atome Classification :
(47 SA)
........----.10........20.......-.30-........40........50........60........70.......---.80........90....-------....100.......110.......120.......130.......140.......150.------.----------...------..-160.......170.-.----.....180.......190.......200.......210.......220.......230
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
N
L
E
S
LP----K
H
L
A
I
I
MDGNSRWANSQG
R
V
-
K
I
D
-
G
YRKG
S
E
V
A
Y
D
I
A
K
H
C
I
A
L
A
I
P
Y
L
T
L
Y
A
F
S
M
E
N
WLRPKEET
D
C
L
F
D
L
---
F
Y
S
I
LTDRD
K
V
N
F
F
H
N
Y
-------
N
I
K
L
N
F
VGNLSLL
P
G
K
I
L
N
Q
I
K
E
S
E
E
M
TRKND
G
L
L
L
T
V
A
VSYG
A
K
Q
E
I
I
H
A
V
R
N
I
T
R
K------N----------IDC------V
S
-
E
D
E
F
E
K
F
L
YTKDLP-K----
L
D
L
L
I
RTG
G
E
K
R
L
S
N
F
L
L
W
Q
A
A
Y
A
E
L
Y
F
CDTLWPDF
S
C
Q
D
L
S
K
A
L
E
D
Y
T
K
R
E
K
RYGR
4
PsiBlast_PDB
97.62
41%
-114
- C10 -
1X07
3
UPPS_ECOLI
A:
[11-240]
----
E
K
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
3
PsiBlast_PDB
96.20
41%
-110
- C10 -
1X06
4
UPPS_ECOLI
A:
[12-240]
-----
K
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
95
HHSearch
96.10
40%
-114
- C10 -
2VG3
6
DPDS_MYCTU
A:
[50-283]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
---
N
R
D
V
V
R
R
R
--
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
------
V
A
A
GRLN----
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
2
PsiBlast_PDB
96.08
41%
-116
- C10 -
1V7U
2
UPPS_ECOLI
A:
[13-239]
------
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
------
31
PsiBlast_CBE
95.77
41%
-114
- C10 -
2E9D
1
UPPS_ECOLI
B:
[17-243]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
----------
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
F
--
40
PsiBlast_CBE
95.55
40%
-109
- C10 -
1X08
3
UPPS_ECOLI
A:
[13-240]
------
L
P
AHGC
R
H
V
A
I
I
M
A
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
37
PsiBlast_CBE
95.53
41%
-112
- C10 -
1UEH
9
UPPS_ECOLI
B:
[17-241]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
----
39
PsiBlast_CBE
95.50
40%
-110
- C10 -
1X09
3
UPPS_ECOLI
A:
[11-239]
----
E
K
L
P
AHGC
R
H
V
A
I
I
M
A
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
------
13
PsiBlast_PDB
95.17
41%
-117
- C10 -
3SGV
2
UPPS_ECOLI
B:
[13-240]
------
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
-----------
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
12
PsiBlast_PDB
95.04
41%
-114
- C10 -
3SGT
1
UPPS_ECOL6
B:
[13-240]
------
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
---
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
35
PsiBlast_CBE
94.93
41%
-115
- C10 -
2E98
3
UPPS_ECOLI
B:
[17-243]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
----------
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
F
--
27
PsiBlast_CBE
94.76
41%
-117
- C10 -
3WYJ
1
UPPS_ECOLI
A:
[14-240]
-------
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
-----
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
92
HHSearch
94.55
42%
-115
* C10 *
3SGV
2
UPPS_ECOLI
B:
[14-240]
---
P
A
H
G
C
----
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
-----------
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
E
--
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
------
V
Q
Q
GNLQ----
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
51
PsiBlast_CBE
94.40
39%
-100
- C10 -
2VG3
7
DPDS_MYCTU
B:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
1
PsiBlast_PDB
94.38
41%
-119
- C10 -
1UEH
4
UPPS_ECOLI
A:
[13-240]
------
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
--------------
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
16
PsiBlast_PDB
94.23
41%
-111
- C10 -
4H2J
1
UPPS_ECOLI
A:
[13-240]
------
L
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
-----------
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
30
PsiBlast_CBE
94.16
41%
-112
- C10 -
3SGV
3
UPPS_ECOLI
A:
[17-238]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
-------
34
PsiBlast_CBE
94.15
41%
-115
- C10 -
2E99
2
UPPS_ECOLI
B:
[17-243]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
----------
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
F
--
25
PsiBlast_CBE
94.11
41%
-113
- C10 -
4H2M
1
UPPS_ECOLI
B:
[17-239]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
----------
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
------
6
PsiBlast_PDB
94.08
41%
-110
- C10 -
2E99
3
UPPS_ECOLI
A:
[14-240]
-------
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
52
PsiBlast_CBE
93.92
39%
-98
- C10 -
2VG3
6
DPDS_MYCTU
A:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
V
A
A
GRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
53
PsiBlast_CBE
93.84
39%
-99
- C10 -
2VG2
5
DPDS_MYCTU
D:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
47
PsiBlast_CBE
93.84
39%
-99
- C10 -
4ONC
2
DPDS_MYCTU
B:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
V
A
A
GRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
5
PsiBlast_PDB
93.79
41%
-111
- C10 -
2E98
4
UPPS_ECOLI
A:
[15-240]
--------AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
49
PsiBlast_CBE
93.76
39%
-101
- C10 -
2VG3
3
DPDS_MYCTU
D:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
56
PsiBlast_CBE
93.71
39%
-97
- C10 -
2VG2
9
DPDS_MYCTU
A:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
V
A
A
GRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
54
PsiBlast_CBE
93.68
39%
-94
- C10 -
2VG2
8
DPDS_MYCTU
C:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
48
PsiBlast_CBE
93.59
39%
-95
- C10 -
4ONC
1
DPDS_MYCTU
A:
[50-280]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
V
A
A
GRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
---
33
PsiBlast_CBE
93.39
41%
-117
- C10 -
2E9A
1
UPPS_ECOLI
B:
[17-242]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
------------
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
---
9
PsiBlast_PDB
93.20
41%
-113
- C10 -
2E9D
2
UPPS_ECOLI
A:
[16-240]
--------HGC-
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
-------
A
Q
E
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
50
PsiBlast_CBE
93.14
39%
-94
- C10 -
2VG3
6
DPDS_MYCTU
C:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
7
PsiBlast_PDB
93.02
41%
-111
- C10 -
2E9A
2
UPPS_ECOLI
A:
[14-240]
-------
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
---------
V
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
55
PsiBlast_CBE
92.97
39%
-100
- C10 -
2VG2
6
DPDS_MYCTU
B:
[50-282]
-
I
P
A
D
R
L
P
----
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
--
F
L
M
---
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
-------
G
V
R
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
R
E
VAAGRL
N
----------
P
E
R
------
I
T
-
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
-
D
----
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
S
45
PsiBlast_CBE
92.59
38%
-111
- C10 -
4Q9M
8
ISPT_STRR6
B:
[12-239]
-----
Q
V
P
----
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
PVE
F
Y
D
-----
N
Y
V
P
E
L
H
A
N
-------
N
V
K
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
Q
D
------
V
----------
L
D
A
KINPGD
I
T
-
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
-
K
DLRD
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
------
32
PsiBlast_CBE
92.44
41%
-115
- C10 -
2E9C
1
UPPS_ECOLI
B:
[17-239]
--------GC--
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
----------
S
A
L
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
------
46
PsiBlast_CBE
92.30
38%
-107
- C10 -
4Q9M
12
ISPT_STRR6
A:
[12-240]
-----
Q
V
P
----
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
PVE
F
Y
D
-----
N
Y
V
P
E
L
H
A
N
-------
N
V
K
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
Q
D
------
V
----------
L
D
A
KINPGD
I
T
-
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
-
K
DLRD
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
H
-----
58
PsiBlast_CBE
90.89
36%
-102
- C10 -
4H8E
3
ISPT_STAAN
A:
[19-251]
-
L
D
S
S
N
I
P
----
E
H
I
A
I
I
M
D
G
N
G
R
W
A
K
K
R
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
I
K
K
I
T
R
I
A
S
D
I
G
V
K
Y
L
T
L
Y
A
F
S
T
E
N
W
S
R
P
E
S
E
V
N
Y
I
M
N
L
------------
P
V
N
F
L
K
T
F
L
P
E
L
I
E
K
N
V
K
V
E
T
I
G
F
T
D
K
L
P
K
S
T
I
E
A
I
N
N
A
K
E
K
T
A
N
N
T
G
L
K
L
I
F
A
I
N
Y
G
G
R
A
E
L
V
H
S
I
K
N
M
F
D
E
L
H
Q
Q
GL
N
----------
S
D
I
------
I
D
-
E
T
Y
I
N
N
H
L
M
T
K
D
Y
P
-
D
----
P
E
L
L
I
R
T
S
G
E
Q
R
I
S
N
F
L
I
W
Q
V
S
Y
S
E
F
I
F
N
Q
K
L
W
P
D
F
D
E
D
E
L
I
K
C
I
K
I
Y
Q
S
R
Q
R
R
F
G
G
57
PsiBlast_CBE
90.76
36%
-103
- C10 -
4U82
3
ISPT_STAAN
A:
[19-251]
-
L
D
S
S
N
I
P
----
E
H
I
A
I
I
M
D
G
N
G
R
W
A
K
K
R
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
I
K
K
I
T
R
I
A
S
D
I
G
V
K
Y
L
T
L
Y
A
F
S
T
E
N
W
S
R
P
E
S
E
V
N
Y
I
M
N
L
------------
P
V
N
F
L
K
T
F
L
P
E
L
I
E
K
N
V
K
V
E
T
I
G
F
T
D
K
L
P
K
S
T
I
E
A
I
N
N
A
K
E
K
T
A
N
N
T
G
L
K
L
I
F
A
I
N
Y
G
G
R
A
E
L
V
H
S
I
K
N
M
F
D
E
L
H
Q
Q
GL
N
----------
S
D
I
------
I
D
-
E
T
Y
I
N
N
H
L
M
T
K
D
Y
P
-
D
----
P
E
L
L
I
R
T
S
G
E
Q
R
I
S
N
F
L
I
W
Q
V
S
Y
S
E
F
I
F
N
Q
K
L
W
P
D
F
D
E
D
E
L
I
K
C
I
K
I
Y
Q
S
R
Q
R
R
F
G
G
97
HHSearch
90.54
36%
-112
- C10 -
2VG0
2
ZFPP_MYCTU
A:
[1-227]
-----
D
L
P
----
R
H
I
A
V
L
C
D
G
N
R
R
W
A
R
S
A
G
Y
D
D
V
S
Y
-
G
Y
R
M
G
A
A
K
I
A
E
M
L
R
W
C
H
E
A
G
I
E
L
A
T
V
Y
L
L
S
T
E
N
L
Q
R
D
P
D
E
L
A
A
L
I
E
I
---
I
T
D
V
V
E
E
I
--
C
A
--
P
A
N
-------
H
W
S
V
R
T
V
G
D
L
G
L
I
G
E
E
P
A
R
R
L
R
G
A
V
E
S
T
P
E
V
A
S
F
H
V
N
V
A
V
G
Y
G
G
R
R
E
I
V
D
A
V
R
A
L
L
S
K
------
E
L
A
N
GAT
A
E
E
L
V
D
A
------
V
T
-
V
E
G
I
S
E
N
L
Y
T
S
G
Q
P
-
D
----
P
D
L
V
I
R
T
S
G
E
Q
R
L
S
G
F
L
L
W
Q
S
A
Y
S
E
M
W
F
T
E
A
H
W
P
A
F
R
H
V
D
F
L
R
A
L
R
D
Y
S
A
R
------
28
PsiBlast_CBE
90.40
41%
-109
- C10 -
3TH8
1
UPPS_ECOLI
B:
[14-239]
-------
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
---------------
M
E
L
---
F
V
W
A
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
------
60
PsiBlast_CBE
90.29
40%
-101
- C10 -
2DTN
1
ISPT_HELPY
B:
[15-241]
------
T
L
----
K
H
L
A
I
I
M
D
G
N
G
R
W
A
K
L
K
N
K
A
-
R
A
Y
-
G
H
K
K
G
V
K
T
L
K
D
I
T
I
W
C
A
N
H
K
L
E
C
L
T
L
Y
A
----------------
M
K
M
---
L
K
K
Y
L
K
D
-
E
R
S
T
Y
L
D
N
--------
N
I
R
F
R
A
I
G
D
L
E
G
F
S
K
E
L
R
D
T
I
L
Q
L
E
N
D
T
R
H
F
K
D
F
T
Q
V
L
A
L
N
Y
G
S
K
N
E
L
S
R
A
F
K
S
L
L
E
S
------
P
---------------------L
E
N
E
I
S
N
R
L
D
T
R
N
L
P
-
E
----
V
D
L
L
L
R
T
G
G
E
M
R
L
S
N
F
L
L
W
Q
S
S
Y
A
E
L
F
F
T
P
I
L
W
P
D
F
T
P
K
D
L
E
N
I
I
S
D
F
Y
K
R
V
R
K
F
G
E
8
PsiBlast_PDB
90.19
41%
-109
- C10 -
2E9C
3
UPPS_ECOLI
A:
[14-240]
-------
P
AHGC
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
----------------------
L
D
S
--
E
V
K
S
L
H
R
H
-------
N
V
R
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
E
K
V
Q
Q
GNL
Q
----------
P
D
Q
------
I
D
-
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
-
P
----
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
-----
67
PsiBlast_CBE
88.92
33%
-117
- C10 -
2VG1
6
ZFPP_MYCTU
B:
[3-228]
------
L
P
----
R
H
I
A
V
L
C
D
G
N
R
R
W
A
R
S
A
G
Y
D
-
D
V
S
Y
G
Y
R
M
G
A
A
K
I
A
E
M
L
R
W
C
H
E
A
G
I
E
L
A
T
V
Y
L
L
S
T
E
N
L
Q
R
D
P
D
E
L
A
A
L
I
E
I
---
I
T
D
V
V
---
E
E
I
C
A
P
A
N
H
--------
W
S
V
R
T
V
G
D
L
G
L
I
G
E
E
P
A
R
R
L
R
G
A
V
E
S
T
P
E
V
A
S
F
H
V
N
V
A
V
G
Y
G
G
R
R
E
I
V
D
A
V
R
A
L
L
S
K
------
E
LANGATAEEL
V
D
A
------
V
T
-
V
E
G
I
S
E
N
L
Y
T
S
G
Q
P
-
D
----
P
D
L
V
I
R
T
S
G
E
Q
R
L
S
G
F
L
L
W
Q
S
A
Y
S
E
M
W
F
T
E
A
H
W
P
A
F
R
H
V
D
F
L
R
A
L
R
D
Y
S
A
R
------
64
PsiBlast_CBE
88.37
33%
-113
- C10 -
2VG0
2
ZFPP_MYCTU
A:
[2-227]
------
L
P
----
R
H
I
A
V
L
C
D
G
N
R
R
W
A
R
S
A
G
Y
D
-
D
V
S
Y
G
Y
R
M
G
A
A
K
I
A
E
M
L
R
W
C
H
E
A
G
I
E
L
A
T
V
Y
L
L
S
T
E
N
L
Q
R
D
P
D
E
L
A
A
L
I
E
I
---
I
T
D
V
V
---
E
E
I
C
A
P
A
N
H
--------
W
S
V
R
T
V
G
D
L
G
L
I
G
E
E
P
A
R
R
L
R
G
A
V
E
S
T
P
E
V
A
S
F
H
V
N
V
A
V
G
Y
G
G
R
R
E
I
V
D
A
V
R
A
L
L
S
K
------
E
L
A
N
GAT
A
E
E
L
V
D
A
------
V
T
-
V
E
G
I
S
E
N
L
Y
T
S
G
Q
P
-
D
----
P
D
L
V
I
R
T
S
G
E
Q
R
L
S
G
F
L
L
W
Q
S
A
Y
S
E
M
W
F
T
E
A
H
W
P
A
F
R
H
V
D
F
L
R
A
L
R
D
Y
S
A
R
------
61
PsiBlast_CBE
87.02
38%
-112
- C10 -
3UGS
2
ISPT_CAMJE
B:
[8-225]
------------
K
H
L
A
V
V
M
D
G
N
R
----------------
S
Q
G
V
K
T
M
Q
K
L
M
E
V
C
M
E
E
N
I
S
N
L
S
L
F
A
F
S
T
E
N
W
K
R
P
K
D
E
I
D
F
I
F
E
L
---
L
D
R
C
L
D
--
E
A
L
E
K
F
E
K
N
-------
N
V
R
L
R
A
I
G
D
L
S
R
L
E
D
K
V
R
E
K
I
T
L
V
E
E
K
T
K
H
C
D
A
L
C
V
N
L
A
I
S
Y
G
A
R
D
E
I
I
R
A
A
K
R
V
I
E
K
------
K
----------
L
E
L
------
N
E
-
E
N
L
T
Q
N
L
----
D
L
P
L
D
----
V
D
L
M
L
R
V
G
N
A
K
R
L
S
N
F
L
L
W
Q
C
S
Y
A
E
I
Y
F
S
E
T
L
F
P
S
L
T
K
R
E
F
K
R
I
I
K
E
F
R
N
R
E
R
T
F
G
K
62
PsiBlast_CBE
86.38
38%
-116
- C10 -
3UGS
2
ISPT_CAMJE
A:
[8-224]
------------
K
H
L
A
V
V
M
D
G
N
R
------------------
G
V
K
T
M
Q
K
L
M
E
V
C
M
E
E
N
I
S
N
L
S
L
F
A
F
S
T
E
N
W
K
R
P
K
D
E
I
D
F
I
F
E
L
---
L
D
R
C
L
D
--
E
A
L
E
K
F
E
K
N
-------
N
V
R
L
R
A
I
G
D
L
S
R
L
E
D
K
V
R
E
K
I
T
L
V
E
E
K
T
K
H
C
D
A
L
C
V
N
L
A
I
S
Y
G
A
R
D
E
I
I
R
A
A
K
R
V
I
E
K
------
K
----------
L
E
L
------
N
E
-
E
N
L
T
Q
N
L
----
D
L
P
L
D
----
V
D
L
M
L
R
V
G
N
A
K
R
L
S
N
F
L
L
W
Q
C
S
Y
A
E
I
Y
F
S
E
T
L
F
P
S
L
T
K
R
E
F
K
R
I
I
K
E
F
R
N
R
E
R
T
F
G
-
93
HHSearch
85.65
38%
-114
- C10 -
3UGS
2
ISPT_CAMJE
B:
[4-225]
----
M
N
E
L
----
K
H
L
A
V
V
M
D
G
N
R
----------------
S
Q
G
V
K
T
M
Q
K
L
M
E
V
C
M
E
E
N
I
S
N
L
S
L
F
A
F
S
T
E
N
W
K
R
P
K
D
E
I
D
F
I
F
E
L
---
L
D
R
C
L
D
E
A
--
L
E
K
F
E
K
N
-------
N
V
R
L
R
A
I
G
D
L
S
R
L
E
D
K
V
R
E
K
I
T
L
V
E
E
K
T
K
H
C
D
A
L
C
V
N
L
A
I
S
Y
G
A
R
D
E
I
I
R
A
A
K
R
V
I
E
K
-----------------
K
L
E
------
L
N
-
E
E
N
L
T
Q
N
L
D
--
L
P
L
-
D
----
V
D
L
M
L
R
V
G
N
A
K
R
L
S
N
F
L
L
W
Q
C
S
Y
A
E
I
Y
F
S
E
T
L
F
P
S
L
T
K
R
E
F
K
R
I
I
K
E
F
R
N
R
E
R
T
F
G
K