@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1205: (2016-03-23 )
MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIRYLQSIQQTLNN
Atome Classification :
(22 SA)
--------------.........-10---.---...---.....---20........30........40........50........60........70..-..-..-..80........90........100.......110.......120.......130.......140.......150.......160.......170.-......180.......190.......200.-..-..-..210.......220.------.-..------....230.......240-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------M
T
K
L
F
I
P
Y
I-M----G---N
K
D
---
L
IEN
A
---
T
L
LSENGA
D
I
I
E
IGVPFSDPVADG
P
V
I
M
E
A
G
Q
Q
A
I
K
QGI
T
I
D
Y
I
F
N
Q
L
E
KHG
D
Q
-
I
K
-
C
N
-
Y
V
L
M
T
Y
Y
N
I
I
C
HY
G
E
Q
A
F
F
E
K
C
R
DTG
V
Y
G
L
IIPDL
P
Y
E
L
S
Q
R
L
K
Q
Q
F
S
HYG
V
K
I
I
S
L
V
A
MTT
D
D
K
R
I
K
D
I
V
S
HAE
G
F
I
Y
T
V
T
M
NATTGQNGAF
H
P
E
-
L
K
R
K
I
E
S
I
K
A
I
ANV
P
V
V
A
GFGIR
T
P
Q
H
V
A
D
-
I
K
-
E
V-ADG
I
V
I
G
S
E
I
V
K
R
F
-K------S-N
T
------
R
E
E
I
I
R
Y
L
Q
S
I
Q
Q
T
LNN-
1
PsiBlast_PDB
93.35
34%
-136
- C3 -
1RD5
2
TRPA_MAIZE
A:
[20-259]
------------------
F
I
P
Y
I
T
A
----
G
---
D
P
D
---
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
A
V
L
E
M
L
R
E
V
T
P
E
-
L
S
-
C
P
-
V
V
L
L
S
Y
Y
K
P
I
M
F
R
S
----
L
A
K
M
K
E
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
P
R
-
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
V
K
Q
-
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
E
------
A
-
A
S
------
P
K
Q
G
L
R
R
L
E
E
Y
A
R
G
M
K
N
-
32
HHSearch
93.09
35%
-139
- C3 -
2EKC
-
TRPA_AQUAE
A:
[15-261]
--------------
R
E
K
A
L
V
S
Y
L
-
M
----
V
G--
Y
P
D
Y
E
T
S
L
K
A
F
---
K
E
V
L
K
N
G
T
D
I
L
E
I
G
F
P
F
S
D
P
V
A
D
G
P
T
I
Q
V
A
H
E
V
A
L
K
N
G
I
R
F
E
D
V
L
E
L
S
E
T
L
R
K
E
F
P
D
-
I
P
-
F
L
L
M
T
Y
Y
N
P
I
F
R
I
G
L
E
K
F
C
R
L
S
R
E
K
G
I
D
G
F
I
V
P
D
L
P
P
E
E
A
E
E
L
K
A
V
M
K
K
Y
V
L
S
F
V
P
L
G
A
P
T
S
T
R
K
R
I
K
L
I
C
E
A
A
D
E
M
T
Y
F
V
S
V
T
G
---------
Y
E
R
I
K
K
K
V
E
E
Y
R
E
L
C
D
K
P
V
V
V
G
F
G
V
S
K
K
E
H
A
R
E
-
I
G
-
S
F
-
A
D
G
V
V
V
G
S
A
L
V
K
L
A
-
G
------
Q
-
K
K
------
I
E
D
L
G
N
L
V
K
E
L
K
E
G
L
R
--
37
HHSearch
91.35
35%
-136
* C3 *
1RD5
2
TRPA_MAIZE
A:
[17-261]
---------------
K
T
A
F
I
P
Y
I
-
T
----
A
G--
D
P
D
L
A
T
T
A
E
A
L
---
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
A
V
L
E
M
L
R
E
V
T
P
E
-
L
S
-
C
P
-
V
V
L
L
S
Y
Y
K
P
I
M
F
----
R
S
L
A
K
M
K
E
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
P
R
-
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
V
K
Q
-
I
A
Q
W
G
-
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
-
G
------
E
-
A
A
S
P
K
Q
G
-
L
R
R
L
E
E
Y
A
R
G
M
K
N
A
L
---
3
PsiBlast_PDB
90.79
34%
-127
- C3 -
1TJR
1
TRPA_MAIZE
A:
[19-258]
------------------
F
I
P
Y
I
T
A
----
G
---
D
P
D
---
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
Y
I
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
A
V
L
E
M
L
R
E
V
T
P
E
-
L
S
-
C
P
-
V
V
L
L
S
Y
Y
K
P
I
M
S
R
S
----
L
A
E
M
K
E
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
N
G
V
T
G
P
R
A
N
V
N
P
R
-
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
V
K
Q
-
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
E
------
A
-
A
S
------
P
K
Q
G
L
R
R
L
E
E
Y
A
R
G
M
K
N
-
21
PsiBlast_CBE
89.04
34%
-140
- C3 -
1RD5
2
TRPA_MAIZE
B:
[20-259]
------------------
F
I
P
Y
I
T
A
----
G
---
D
P
D
---
L
A
T
T
A
E
A
L
R
L
L
D
G
C
G
A
D
V
I
E
L
G
V
P
C
S
D
P
--
D
G
P
I
I
Q
A
S
V
A
R
A
L
A
S
G
T
T
M
D
A
V
L
E
M
L
R
E
V
T
P
E
-
L
S
-
C
P
-
V
V
L
L
S
Y
Y
K
P
I
M
F
R
S
----
L
A
K
M
K
E
A
G
V
H
G
L
I
V
P
D
L
P
Y
V
A
A
H
S
L
W
S
E
A
K
N
N
N
L
E
L
V
L
L
T
T
P
A
I
P
E
D
R
M
K
E
I
T
K
A
S
E
G
F
V
Y
L
V
S
V
-----------
P
R
-
V
E
S
L
I
Q
E
V
K
K
V
T
N
K
P
V
A
V
G
F
G
I
S
K
P
E
H
V
K
Q
-
I
A
-
Q
W
G
A
D
G
V
I
I
G
S
A
M
V
R
Q
L
G
E
------
A
-
A
S
------
P
K
Q
G
L
R
R
L
E
E
Y
A
R
G
M
K
N
-
7
PsiBlast_PDB
87.37
33%
-135
- C3 -
2DZP
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
N
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
11
PsiBlast_PDB
86.75
33%
-132
- C3 -
1GEQ
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
-------
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
10
PsiBlast_PDB
86.38
33%
-129
- C3 -
2DZW
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
12
PsiBlast_PDB
86.32
33%
-129
- C3 -
1WDW
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
------
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
14
PsiBlast_PDB
85.36
33%
-127
- C3 -
2DZS
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
A
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
52
Fugue
85.25
30%
-128
- C3 -
1GEQ
-
TRPA_PYRFU
A:
[1-248]
-----------MFK-
D
G
S
L
I
P
Y
L
-
T
A
GDP
D
---
K
Q
S
---
T
L
N
F
L
---
L
A
L
D
E
Y
-
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
S-
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
-----
E
--
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
-
L
L
-
K
E
G
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
K--------
G
R
E
A
T
E
F
L
K
K
K
V
E
E
L
L
G
I
16
PsiBlast_PDB
85.13
32%
-135
- C3 -
2DZV
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
A
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
9
PsiBlast_PDB
84.98
33%
-132
- C3 -
2DZU
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
N
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
15
PsiBlast_PDB
84.82
33%
-131
- C3 -
2E09
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
A
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
13
PsiBlast_PDB
84.63
33%
-131
- C3 -
2DZX
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
D
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
A
A
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
4
PsiBlast_PDB
84.51
36%
-140
- C3 -
2EKC
-
TRPA_AQUAE
A:
[42-262]
---------------------------------------------------
K
N
G
T
D
I
L
E
I
G
F
P
F
S
D
P
V
A
D
G
P
T
I
Q
V
A
H
E
V
A
L
K
N
G
I
R
F
E
D
V
L
E
L
S
E
T
L
R
K
E
-
F
P
D
I
P
-
F
L
L
M
T
Y
Y
N
P
I
F
R
I
G
L
E
K
F
C
R
L
S
R
E
K
G
I
D
G
F
I
V
P
D
L
P
P
E
E
A
E
E
L
K
A
V
M
K
K
Y
V
L
S
F
V
P
L
G
A
P
T
S
T
R
K
R
I
K
L
I
C
E
A
A
D
E
M
T
Y
F
V
S
V
T
G
--------
Y
E
R
-
I
K
K
K
V
E
E
Y
R
E
L
C
D
K
P
V
V
V
G
F
G
V
S
K
K
E
H
A
R
E
-
I
G
-
S
F
-
A
D
G
V
V
V
G
S
A
L
V
K
L
A
-
G
------
Q
-
K
K
------
I
E
D
L
G
N
L
V
K
E
L
K
E
G
L
R
E
-
8
PsiBlast_PDB
83.78
33%
-130
- C3 -
2DZT
-
TRPA_PYRFU
A:
[7-233]
------------------
L
I
P
Y
L
-
T
----
A
GDP
D
K
Q
---
S
T
L
N
F
---
L
L
A
L
D
E
Y
A
G
A
I
E
L
G
I
P
F
S
D
P
I
A
D
G
K
T
I
Q
E
S
H
Y
R
A
L
K
N
G
F
K
L
R
E
A
F
W
I
V
K
E
F
R
R
H
-
S
S
-
T
P
-
I
V
L
M
T
Y
Y
N
P
I
Y
R
A
G
V
R
N
F
L
A
E
A
K
A
S
G
V
A
G
I
L
V
V
D
L
P
V
F
H
A
K
E
F
T
E
I
A
R
E
E
G
I
K
T
V
F
L
A
A
P
N
T
P
D
E
R
L
K
V
I
D
D
M
T
T
G
F
V
Y
L
V
S
L
Y
G
T
----
E
E
I
P
K
T
-
A
Y
D
L
L
R
R
A
K
R
I
C
R
N
K
V
A
V
G
F
G
V
S
K
R
E
H
V
V
S
L
L
K
-
E
G
-
A
N
G
V
V
V
G
S
A
L
V
K
I
I
-
G
------
E
-
K
G
------
R
E
----------------
53
Fugue
83.27
28%
-123
- C3 -
2TYS
-
TRPA_SALTY
A:
[1-268]
M
E
R
Y
E
N
L
F
A
Q
L
N
D
R
R
E
G
A
F
V
P
F
V
-
T
LGDP
G
---
I
E
Q
---
S
L
K
I
I
---
D
T
L
I
D
A
G
A
D
A
L
E
L
G
V
P
F
S
D
P
L
A
D
G
P
T
I
Q
N
A
N
L
R
A
F
A
A
G
V
T
P
A
Q
C
F
E
M
L
A
L
I
R
E
K
-
H
P
-
T
I
P
I
G
L
L
M
Y
A
N
L
V
F
N
N
G
I
D
A
F
Y
A
R
C
E
Q
V
G
V
D
S
V
L
V
A
D
V
P
V
E
E
S
A
P
F
R
Q
A
A
L
R
H
N
I
A
P
I
F
I
C
P
P
N
A
D
D
D
L
L
R
Q
V
A
S
Y
G
R
G
Y
T
Y
L
L
S
-------------
P
-
L
H
H
L
I
E
K
L
K
E
Y
H
A
A
P
A
L
Q
G
F
G
I
S
S
P
E
Q
V
S
A
-
A
V
-
R
A
G
A
A
G
A
I
S
G
S
A
I
V
K
I
I
-
E
K
N
L
AS
P
K
-
Q
M
------
L
A
E
L
R
S
F
V
S
A
M
K
A
A
S
R
A
-
36
HHSearch
82.91
32%
-143
- C3 -
1UJP
1
TRPA_THET2
A:
[15-250]
---------------
R
A
A
L
I
P
Y
L
-
T
----
A
G--
F
P
S
R
E
G
F
L
Q
A
V
---
E
E
V
L
-
P
Y
A
D
L
L
E
I
G
L
P
Y
S
D
----
G
P
V
I
Q
R
A
S
E
L
A
L
R
K
G
M
S
V
Q
G
A
L
E
L
V
R
E
V
R
A
L
-
T
E
-
K
P
-
L
F
L
M
T
Y
L
N
P
V
L
A
W
G
P
E
R
F
F
G
L
F
K
Q
A
G
A
T
G
V
I
L
P
D
L
P
P
D
E
D
P
G
L
V
R
L
A
Q
E
I
G
L
E
T
V
F
L
L
A
P
T
S
T
D
A
R
I
A
T
V
V
R
H
A
T
G
F
V
Y
A
V
S
V
------------
E
-
V
K
D
L
V
R
R
I
K
A
R
T
A
L
P
V
A
V
G
F
G
V
S
G
K
A
T
A
A
Q
-
A
--
A
V
-
A
D
G
V
V
V
G
S
A
L
V
R
A
L
-
E
------
E
---------------------------
33
HHSearch
81.62
26%
-112
- C3 -
3VND
5
?
A:
[17-267]
---------------
K
G
A
F
V
P
F
V
-
T
----
I
G--
D
P
S
P
E
L
S
L
K
I
I
---
Q
T
L
V
D
N
G
A
D
A
L
E
L
G
F
P
F
S
D
P
L
A
D
G
P
V
I
Q
G
A
N
L
R
S
L
A
A
G
T
T
S
S
D
C
F
D
I
I
T
K
V
R
A
Q
H
P
D
-
M
P
-
I
G
L
L
L
Y
A
N
L
V
F
A
N
G
I
D
E
F
Y
T
K
A
Q
A
A
G
V
D
S
V
L
I
A
D
V
P
V
E
E
S
A
P
F
S
K
A
A
K
A
H
G
I
A
P
I
F
I
A
P
P
N
A
D
A
D
T
L
K
M
V
S
E
Q
G
E
G
Y
T
Y
L
L
S
R
A
G
V
T
--------
P
-
I
E
N
I
L
T
Q
L
A
E
F
N
A
P
P
P
L
L
G
F
G
I
A
E
P
E
Q
V
R
A
-
A
I
K
A
G
-
A
A
G
A
I
S
G
S
A
V
V
K
I
I
-
E
------
A
-
H
Q
HD
E
A
T
L
L
A
K
L
A
E
F
T
T
A
M
K
A
A
T
---
5
PsiBlast_PDB
76.45
33%
-138
- C3 -
1UJP
1
TRPA_THET2
A:
[43-267]
------------------------------------------------------
A
D
L
L
E
I
G
L
P
Y
S
D
----
G
P
V
I
Q
R
A
S
E
L
A
L
R
K
G
M
S
V
Q
G
A
L
E
L
V
R
E
V
R
A
L
-
T
E
-
K
P
-
L
F
L
M
T
Y
L
N
P
V
L
A
W
G
P
E
R
F
F
G
L
F
K
Q
A
G
A
T
G
V
I
L
P
D
L
P
P
D
E
D
P
G
L
V
R
L
A
Q
E
I
G
L
E
T
V
F
L
L
A
P
T
S
T
D
A
R
I
A
T
V
V
R
H
A
T
G
F
V
Y
A
V
S
V
------------
E
-
V
K
D
L
V
R
R
I
K
A
R
T
A
L
P
V
A
V
G
F
G
V
-
S
G
K
A
T
A
A
-
Q
A
-
A
V
-
A
D
G
V
V
V
G
S
A
L
V
R
A
L
-
E
------
E
-
G
--------
R
S
L
A
P
L
L
Q
E
I
R
Q
G
L
Q
R
-
6
PsiBlast_PDB
75.43
33%
-135
- C3 -
1WXJ
5
TRPA_THET2
A:
[43-255]
------------------------------------------------------
A
D
L
L
E
I
G
L
P
Y
S
-----
G
P
V
I
Q
R
A
S
E
L
A
L
R
K
G
M
S
V
Q
G
A
L
E
L
V
R
E
V
R
A
L
-
T
E
-
K
P
-
L
F
L
M
T
Y
L
N
P
V
L
A
W
G
P
E
R
F
F
G
L
F
K
Q
A
G
A
T
G
V
I
L
P
D
L
P
P
D
E
D
P
G
L
V
R
L
A
Q
E
I
G
L
E
T
V
F
L
L
A
P
T
S
T
D
A
R
I
A
T
V
V
R
H
A
T
G
F
V
Y
A
V
S
-------------
E
-
V
K
D
L
V
R
R
I
K
A
R
T
A
L
P
V
A
V
G
F
G
V
-
S
G
K
A
T
A
A
-
Q
A
-
A
V
-
A
D
G
V
V
V
G
S
A
L
V
R
A
L
-
E
------
E
-
G
--------
R
S
L
A
P
L
L
Q
E
I
R
Q
G
L
Q
R
-