@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2456: (2016-04-04 )
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
Atome Classification :
(20 SA)
----------------------------.........10........20........30........40....-....50........60........70........80........90..--------.--.-...-------.100.......110.-...----...120...---.-----...130-....---.--..140.....--.-.150.......160.........170--.....-....180.......190.......200--------.-..--....210----.......220.......230------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------MTNTRRST
S
S
L
I
V
HEQPKS
P
I
S
E
K
F
R
G
I
R
S
N
I
M
FANPD
S
A
V
Q
S
I
V
-
I
TSEAPGAG
K
S
T
I
A
A
N
L
A
V
A
Y
AQAG
Y
K
T
L
I
VDGDMRKPTQ
H
Y
I
F
NLPN--------N--E-
G
L
S
-------
S
L
LLNWSTYQ
D
S
I
I
S-TEI----
Q
D
L
D
V
LTSG---P-----IPP
N
P
S
-
E
L
I
T
---
S
--
R
A
F
A
N
L
Y
D
T
L
--L-MNY
N
F
V
I
IDTPP--VNT
V
T
D
A
Q
L
F
----
S
K
FTG-
N
V
V
Y
V
V
NSENN
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
--------
A
-
K
L
--
L
G
V
V
L
N
R----MPKDKSA
S
Y
Y
A
Y
YGTDES--------------------------
1
PsiBlast_PDB
93.42
99%
-98
- C1 -
3BFV
2
CAP8A_STAAU
A:
[42-256]
----------------------------
M
T
N
T
R
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
-
I
T
S
E
A
P
G
A
G
K
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
N
L
P
N
--------
N
--
E
-
G
L
S
-------
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
-
T
E
I
----
E
D
L
D
V
L
T
S
G
---
P
-----
I
P
P
N
P
S
-
E
L
I
T
---
S
--
R
A
F
A
N
L
Y
D
T
L
--
L
-
M
N
Y
N
F
V
I
I
D
T
P
P
--
V
N
T
V
T
D
A
Q
L
F
----
S
K
F
T
G
-
N
V
V
Y
V
V
N
S
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
--------
A
-
K
L
--
L
G
V
V
L
N
R
----
M
P
K
-----------------------------------------
2
PsiBlast_PDB
92.92
99%
-97
- C1 -
2VED
2
?
A:
[42-267]
----------------------------
M
T
N
T
R
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
-
I
T
S
E
A
P
G
A
G
M
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
N
L
P
N
--------
N
--
E
-
G
L
S
-------
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
-
T
E
I
----
E
D
L
D
V
L
T
S
G
---
P
-----
I
P
P
N
P
S
-
E
L
I
T
---
S
--
R
A
F
A
N
L
Y
D
T
L
--
L
-
M
N
Y
N
F
V
I
I
D
T
P
P
--
V
N
T
V
T
D
A
Q
L
F
----
S
K
F
T
G
-
N
V
V
Y
V
V
N
S
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
--------
A
-
K
L
--
L
G
V
V
L
N
R
----
M
P
K
D
K
S
A
S
Y
Y
A
Y
Y
G
------------------------------
21
PsiBlast_CBE
92.46
99%
-96
- C1 -
3BFV
2
CAP8A_STAAU
B:
[42-256]
----------------------------
M
T
N
T
R
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
-
I
T
S
E
A
P
G
A
G
K
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
N
L
P
N
--------
N
--
E
-
G
L
S
-------
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
-
T
E
I
----
E
D
L
D
V
L
T
S
G
---
P
-----
I
P
P
N
P
S
-
E
L
I
T
---
S
--
R
A
F
A
N
L
Y
D
T
L
--
L
-
M
N
Y
N
F
V
I
I
D
T
P
P
--
V
N
T
V
T
D
A
Q
L
F
----
S
K
F
T
G
-
N
V
V
Y
V
V
N
S
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
--------
A
-
K
L
--
L
G
V
V
L
N
R
----
M
P
K
-----------------------------------------
22
PsiBlast_CBE
91.94
99%
-98
- C1 -
2VED
2
?
B:
[42-269]
----------------------------
M
T
N
T
R
R
S
T
S
S
L
I
V
H
E
Q
P
K
S
P
I
S
E
K
F
R
G
I
R
S
N
I
M
F
A
N
P
D
S
A
V
Q
S
I
V
-
I
T
S
E
A
P
G
A
G
M
S
T
I
A
A
N
L
A
V
A
Y
A
Q
A
G
Y
K
T
L
I
V
D
G
D
M
R
K
P
T
Q
H
Y
I
F
N
L
P
N
--------
N
--
E
-
G
L
S
-------
S
L
L
L
N
W
S
T
Y
Q
D
S
I
I
S
-
T
E
I
----
E
D
L
D
V
L
T
S
G
---
P
-----
I
P
P
N
P
S
-
E
L
I
T
---
S
--
R
A
F
A
N
L
Y
D
T
L
--
L
-
M
N
Y
N
F
V
I
I
D
T
P
P
--
V
N
T
V
T
D
A
Q
L
F
----
S
K
F
T
G
-
N
V
V
Y
V
V
N
S
E
N
N
N
K
D
E
V
K
K
G
K
E
L
I
E
A
T
G
--------
A
-
K
L
--
L
G
V
V
L
N
R
----
M
P
K
D
K
S
A
S
Y
Y
A
Y
Y
G
T
D
----------------------------
85
Fugue
67.31
28%
-83
- C1 -
3CIO
2
ETK_ECOLI
A:
[25-290]
GVEAPE
Q
L
E
E
H
GISVY
A
T
I
P
M
S
E
W
L
D
K
R
Q
Q
R
H
R
T
K
N
I
P
F
L
A
V
D
N
P
A
D
S
A
V
E
A
V
R
A
L
R
T
S
L
H
F
A
M
M
E
T
E
N
N
I
L
M
-
I
T
G
A
T
P
D
S
G
K
T
F
V
S
S
T
L
A
A
V
I
A
Q
S
D
Q
K
V
L
F
I
D
A
D
L
R
R
G
Y
S
H
N
L
F
T
V
S
N
--------
E
--
H
-
G
L
S
-------
E
Y
L
A
G
K
D
E
L
N
K
V
I
Q
H
-
F
G
K
----
G
G
F
D
V
I
T
R
G
---
Q
-----
V
P
P
N
P
S
-
E
L
L
M
---
R
--
D
R
M
R
Q
L
L
E
W
A
--
N
-
D
H
Y
D
L
V
I
V
D
T
P
P
--
M
L
A
V
S
D
A
A
V
V
----
G
R
S
V
G
-
T
S
L
L
V
A
R
F
G
L
N
T
A
K
E
V
S
L
S
M
Q
R
L
E
Q
A
G
--------
V
-
N
I
--
K
G
A
I
L
N
G
----
V
I
K
R
A
S
T
A
Y
S
Y
G
Y
N
Y
-----------------------------
94
HHSearch
67.26
32%
-84
- C1 -
3LA6
2
WZC_ECOLI
A:
[66-270]
------------------------------------------
G
N
P
T
D
L
A
I
E
A
I
R
S
L
R
T
S
L
H
F
A
M
M
Q
A
Q
N
N
V
L
M
-
M
T
G
V
S
P
S
I
G
M
T
F
V
C
A
N
L
A
A
V
I
S
Q
T
N
K
R
V
L
L
I
D
C
D
M
R
K
G
Y
T
H
E
L
L
G
T
N
N
--------
V
--
N
-
G
L
S
-------
E
I
L
I
G
Q
G
D
I
T
T
A
A
K
P
-
T
S
I
----
A
K
F
D
L
I
P
R
G
---
Q
-----
V
P
P
N
P
S
-
E
L
L
M
---
S
--
E
R
F
A
E
L
V
N
W
A
--
S
-
K
N
Y
D
L
V
L
I
D
T
P
P
--
I
L
A
V
T
D
A
A
I
V
----
G
R
H
V
G
-
T
T
L
M
V
A
R
Y
A
V
N
T
L
K
E
V
E
T
S
L
S
R
F
E
Q
N
G
--------
I
-
P
V
--
K
G
V
I
L
N
S
----
I
F
R
R
A
S
A
-------------------------------------
95
HHSearch
65.49
30%
-87
- C1 -
3CIO
2
ETK_ECOLI
A:
[78-284]
------------------------------------------
D
N
P
A
D
S
A
V
E
A
V
R
A
L
R
T
S
L
H
F
A
M
M
E
T
E
N
N
I
L
M
-
I
T
G
A
T
P
D
S
G
K
T
F
V
S
S
T
L
A
A
V
I
A
Q
S
D
Q
K
V
L
F
I
D
A
D
L
R
R
G
Y
S
H
N
L
F
T
V
S
N
--------
E
--
H
-
G
L
S
-------
E
Y
L
A
G
K
D
E
L
N
K
V
I
Q
H
-
F
G
K
----
G
G
F
D
V
I
T
R
G
---
Q
-----
V
P
P
N
P
S
-
E
L
L
M
---
R
--
D
R
M
R
Q
L
L
E
W
A
--
N
-
D
H
Y
D
L
V
I
V
D
T
P
P
--
M
L
A
V
S
D
A
A
V
V
----
G
R
S
V
G
-
T
S
L
L
V
A
R
F
G
L
N
T
A
K
E
V
S
L
S
M
Q
R
L
E
Q
A
G
--------
V
-
N
I
--
K
G
A
I
L
N
G
----
V
I
K
R
A
S
T
A
Y
-----------------------------------
3
PsiBlast_PDB
65.31
30%
-87
- C1 -
3CIO
2
ETK_ECOLI
A:
[78-283]
------------------------------------------
D
N
P
A
D
S
A
V
E
A
V
R
A
L
R
T
S
L
H
F
A
M
M
E
T
E
N
N
I
L
M
-
I
T
G
A
T
P
D
S
G
K
T
F
V
S
S
T
L
A
A
V
I
A
Q
S
D
Q
K
V
L
F
I
D
A
D
L
R
R
G
Y
S
H
N
L
F
T
V
S
N
--------
E
--
H
-
G
L
S
-------
E
Y
L
A
G
K
D
E
L
N
K
V
I
Q
H
-
F
G
K
----
G
G
F
D
V
I
T
R
G
---
Q
-----
V
P
P
N
P
S
-
E
L
L
M
---
R
--
D
R
M
R
Q
L
L
E
W
A
--
N
-
D
H
Y
D
L
V
I
V
D
T
P
P
--
M
L
A
V
S
D
A
A
V
V
----
G
R
S
V
G
-
T
S
L
L
V
A
R
F
G
L
N
T
A
K
E
V
S
L
S
M
Q
R
L
E
Q
A
G
--------
V
-
N
I
--
K
G
A
I
L
N
G
----
V
I
K
R
A
S
T
A
------------------------------------
7
PsiBlast_PDB
58.06
27%
-83
- C1 -
1G3R
2
?
A:
[5-172]
-----------------------------------------------------------------------
I
S
-
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
--------
P
--
D
V
T
L
H
-------
D
V
L
A
G
E
A
N
V
E
D
A
I
Y
M
-
T
Q
F
----
D
N
V
Y
V
L
-
P
G
---
A
-----
V
D
W
E
H
V
-
L
K
A
D
---
P
--
R
K
L
P
E
V
I
K
S
L
--
K
-
D
K
F
D
F
I
L
I
D
C
-
P
--
A
G
L
Q
L
D
A
-
M
S
----
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
K
K
A
G
--------
L
-
A
I
--
L
G
F
V
L
N
R
------------------------------------------------
96
HHSearch
58.01
25%
-76
- C1 -
1G3Q
2
?
A:
[2-176]
--------------------------------------------------------------------
G
R
I
I
S
-
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
P-------
D
--
V
-
T
L
H
-------
D
V
L
A
G
E
A
N
V
E
D
A
I
Y
M
-
T
Q
F
----
D
N
V
Y
V
L
P
G
A
---
V
-----
D
W
E
H
V
--
L
K
A
D
---
P
--
R
K
L
P
E
V
I
K
S
L
--
K
-
D
K
F
D
F
I
L
I
D
C
P
A
--
G
L
Q
L
D
-
A
M
S
A
----
M
L
S
G
E
-
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
K
K
A
G
--------
L
-
A
I
--
L
G
F
V
L
N
R
----
Y
G
R
S
----------------------------------------
6
PsiBlast_PDB
57.74
27%
-82
- C1 -
1G3Q
2
?
A:
[5-172]
-----------------------------------------------------------------------
I
S
-
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
--------
P
--
D
V
T
L
H
-------
D
V
L
A
G
E
A
N
V
E
D
A
I
Y
M
-
T
Q
F
----
D
N
V
Y
V
L
-
P
G
---
A
-----
V
D
W
E
H
V
-
L
K
A
D
---
P
--
R
K
L
P
E
V
I
K
S
L
--
K
-
D
K
F
D
F
I
L
I
D
C
-
P
--
A
G
L
Q
L
D
A
-
M
S
----
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
K
K
A
G
--------
L
-
A
I
--
L
G
F
V
L
N
R
------------------------------------------------
4
PsiBlast_PDB
57.44
27%
-86
- C1 -
1ION
2
?
A:
[5-172]
-----------------------------------------------------------------------
I
S
-
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
E
M
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
V-------
N
--
I
-
T
L
H
-------
D
V
L
A
G
D
A
K
L
E
D
A
I
Y
M
-
T
Q
F
----
E
N
V
Y
I
L
------
P
-----
G
A
V
D
W
E
-
H
V
I
K
---
A
DP
R
K
L
P
E
V
I
K
S
L
--
K
-
G
K
Y
D
F
I
L
I
D
C
P
-------
A
G
L
Q
L
R
A
M
S
-
A
M
L
S
G
E
E
A
I
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
M
V
L
K
K
A
G
--------
L
-
A
I
--
L
G
F
I
L
N
R
------------------------------------------------
16
PsiBlast_PDB
54.83
23%
-80
- C2 -
5AUQ
1
?
A:
[16-194]
------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
--------
K
--
E
----------------
F
P
E
E
D
R
G
V
V
P
-
P
T
V
----
H
G
I
K
F
M
T
I
A
YYT--------
L
R
G
K
-
E
-
I
S
---
D
--
A
L
I
E
L
L
T
I
T
R
--
W
-
D
E
L
D
Y
L
V
I
D
M
P
P
GL
G
D
Q
L
L
D
V
L
R
F
----
L
K
-
R
G
-
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
-
K
V
--
I
G
V
V
E
N
-------------------------------------------------
8
PsiBlast_PDB
54.12
30%
-66
* C2 *
2PH1
1
?
A:
[21-213]
-----------------------------------------------------------------------
I
A
-
V
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
L
R
N
A
R
I
A
V
S
--
A
--
E
-
G
L
E
-------
P
V
L
T
Q
--
K
Y
G
I
K
V
M
S
-
M
Q
F
L
L
PK
E
N
T
P
V
I
W
R
G
---
P
-----
L
I
A
G
M
I
-
R
E
F
L
---
G
--
R
V
A
W
G
E
L
D
H
L
--
L
--------
I
D
L
P
P
----
G
T
G
D
A
P
L
T
V
M
Q
D
A
K
P
T
G
--
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
M
A
E
E
T
N
--------
T
-
S
V
--
L
G
L
V
E
N
M
S
Y
F
V
C
P
N
C
G
H
K
S
Y
I
F
G
E
G
K
G
E
S
--------------------------
93
Fugue
54.01
20%
-95
- C1 -
3K9G
12
?
A:
[26-267]
-------------------------------------------------------------------
K
P
K
I
I
T
-
I
A
S
I
K
G
G
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
K
-
N
N
K
V
L
L
I
D
M
D
T
Q
A
S
I
T
S
Y
F
Y
E
K
I
E
--------
K
--
L
-
G
I
N
FTKFN
I
Y
E
I
L
K
E
N
V
D
I
D
S
T
I
I
N
-
V
D
-----
N
N
L
D
L
I
P
S
Y
---
L
-----
T
L
H
N
F
S
-
E
D
K
I
E
HK
D
--
F
L
L
K
T
S
L
G
T
L
--
Y
-
Y
K
Y
D
Y
I
V
I
D
T
N
P
--
S
L
D
V
T
L
K
N
A
L
----
L
-
C
S
D
-
Y
V
I
I
P
M
T
A
E
K
W
A
V
E
S
L
D
L
F
N
F
F
V
R
K
L
N
--------
L
-
F
L
P
I
F
L
I
I
T
R
F
----
K
K
N
R
T
H
K
T
L
F
E
I
L
K
T
K
D
R
FL
G
T
I
S
ENK
D
Y
I
K
E
Y
E
N
I
L
E
I
F
L
K
K
I
101
HHSearch
53.66
21%
-83
* C1 *
3Q9L
3
MIND_ECOLI
A:
[2-187]
--------------------------------------------------------------------
A
R
I
I
V
-
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
--------
R
VV
Y
-
D
F
V
-------
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
----
E
N
L
Y
I
L
P
A
S
---
Q
-----
T
R
D
K
---
D
A
L
T
---
R
--
E
G
V
A
K
V
L
D
D
L
--
K
A
M
D
F
E
F
I
V
C
D
S
P
A
--
G
I
E
-
T
G
A
L
M
A
----
L
Y
F
A
D
-
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
S
K
S
R
R
A
E
N
GEE
P
-
I
K
--
E
H
L
L
L
T
R
----
Y
N
P
G
R
---------------------------------------
12
PsiBlast_PDB
52.72
23%
-78
- C2 -
3VX3
5
?
A:
[16-193]
------------------------------------------------------------------
E
G
V
K
R
I
I
P
V
V
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
F
E
P
--------
K
--
E
----------------
F
P
E
E
D
R
G
V
V
P
-
P
T
V
----
H
G
I
K
F
M
T
I
A
YYT------
T
P
L
R
G
K
-
E
-
I
S
---
D
--
A
L
I
E
L
L
T
I
T
R
--
W
-
D
E
L
D
Y
L
V
I
D
M
P
P
GL
G
D
Q
L
L
D
V
L
R
F
----
L
K
-
R
G
-
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
L
L
K
E
E
G
--------
H
-
K
V
--
I
G
V
V
E
N
-------------------------------------------------
97
HHSearch
52.03
25%
-84
- C1 -
1HYQ
-
?
A:
[2-175]
--------------------------------------------------------------------
V
R
T
I
T
-
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
M
E
G
L-------
P
--
V
-
T
L
Q
-------
N
V
L
A
G
E
A
R
I
D
E
A
I
Y
V
--
G
P
----
G
G
V
K
V
V
P
A
G
---
V
-----
S
L
E
G
L
--
R
K
A
N
---
P
--
E
K
L
E
D
V
L
T
Q
I
--
M
-
E
S
T
D
I
L
L
L
D
A
P
A
--
G
L
E
R
-
S
A
V
I
A
----
I
A
A
A
Q
-
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
E
R
L
G
--------
T
-
K
V
--
L
G
V
V
V
N
R
----
I
T
T
L
----------------------------------------
105
HHSearch
51.96
21%
-78
- C1 -
3K9G
11
?
A:
[26-227]
-------------------------------------------------------------------
K
P
K
I
I
T
-
I
A
S
I
K
G
G
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
K
-
N
N
K
V
L
L
I
D
M
D
T
Q
A
-
S
I
T
S
Y
F
Y
E
K
I
E
K
L
GINFT
K
--
F
-
N
I
Y
-------
E
I
L
K
E
N
V
D
I
D
S
T
I
I
N
--
V
D
----
N
N
L
D
L
I
P
S
Y
---
L
-----
T
L
H
N
F
S
-
E
D
K
I
E
HK
D
--
F
L
L
K
T
S
L
G
T
L
--
Y
-
Y
K
Y
D
Y
I
V
I
D
T
N
P
--
S
L
D
V
-
T
L
K
N
A
----
L
L
C
S
D
-
Y
V
I
I
P
M
T
A
E
K
W
A
V
E
S
L
D
L
F
N
F
F
V
R
K
L
N
--------
L
F
L
P
--
I
F
L
I
I
T
R
----
F
K
K
N
R
---------------------------------------
5
PsiBlast_PDB
51.19
29%
-85
- C1 -
1HYQ
-
?
A:
[2-172]
--------------------------------------------------------------------
V
R
T
I
T
-
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
M
-------------
E
-
G
L
P
-------
V
T
L
Q
N
-------
V
L
A
-
G
E
A
----
R
I
D
E
A
I
Y
V
G
---
P
GG
V
K
V
V
P
A
G
V
S
L
E
G
L
R
---
K
--
A
N
P
E
K
L
E
D
V
L
T
Q
I
-
M
E
S
T
D
I
L
L
L
D
A
P
--
A
G
L
E
R
S
A
V
I
A
----
I
A
A
A
Q
-
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
E
R
L
G
--------
T
-
K
V
--
L
G
V
V
V
N
R
----
I
-------------------------------------------