@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0777: (2016-01-19 )
MLRASFVLLALSCAAPLLSLAEPLRFAGDDGCPYLCPGTPQRPGYLVEALSQVLREPPHFDSLPWPRAVQMVRDGHRDGLVGAYGLDGLRVGSEPIGWVGLAFYTRHDSDWHYSGDASLLGQRLGLAQGYVNNPRFEAWRSQAGDDDLHLQVLGGERVLPRNLQKLLLGRIDVLLEDRDIIEHYLEHHPQLAGQIRRAGELPGRQPLHVGLSPHLPEVDARLAELDEGLRQLRREGTLKVLGERYRLSFE
Atome Classification :
(20 SA)
.........10........20..---------.....-.-30.......-----.40.......---.50....---.--------------------.--.---.60..-.-.....70........80.-.-.-.---.----.-----..90.----.......100.......110.......------.120........--.130.......140.......150......--.160.......170.......180..-.....190.......-----200-----.-----...---....210.......220..-.....230.......240...----....250-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLRA
S
F
V
L
L
A
L
S
C
A
A
P
L
L
S
L
A
E
P
---------
L
R
FAG-D-DGCPYLCPG-----TPQRP
G
Y
L
V
E
---
A
L
S
Q
V
LR---E--------------------P--P---HFDSL-P-
W
P
R
A
V
Q
M
V
RDGHRDG
L
V
G-A-Y-G---L----D-----
G
L
RVG----SEP
I
G
W
V
G
L
A
F
Y
T
RHDSD-WHYSG
D
A
S
------
L
L
--
G
Q
R
L
G
LAQ--GYVNNP
R
F
E
A
W
R
SQAGDD
D
L
H
L
Q
V
LGGERV--
L
P
R
N
L
Q
K
L
L
L
G
R
I
D
V
LLE
D
R
D
I
I
E
H
Y
-
L
E
HH
P
Q
L
A
G
Q
I
R
R
A
G-----E-L-----P-----GRQ---
P
L
HVGLSPHL
P
E
V
D
A
R
L
A
E
-
L
D
E
G
L
R
Q
L
R
RE
G
T
L
K
V
L
G
E
R
Y
----
R
LSFE---
1
PsiBlast_PDB
80.55
23%
-64
- C4 -
2YLN
10
?
A:
[80-275]
----------------------------------------------------------
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
G
---
V
--------------------
K
--
V
---
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
F
D
V
V
A
N
-
Q
-
V
-
G
---
L
----
T
S
P
E
R
Q
A
T
F
D
K
----
S
E
P
Y
S
W
S
G
A
V
L
V
A
H
N
D
S
N
-
I
K
S
I
A
D
I
------------
K
G
V
K
T
A
Q
--
S
L
T
S
N
Y
G
E
K
A
K
A
A
G
A
-----
Q
L
V
P
V
D
G
-----
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
D
Y
-
L
K
K
N
P
N
A
G
V
K
I
V
W
S
A
-------------
P
-----
A
D
E
---
K
V
G
S
G
L
I
V
N
K
G
N
-
D
E
A
V
A
K
-
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
----
F
G
K
D
I
---
24
HHSearch
79.98
18%
-76
- C4 -
3H7M
1
?
A:
[7-231]
-----------------
R
D
R
H
R
T
---------
I
V
V
G
G
-
D
R
D
Y
P
P
Y
E
F
I
D
Q----
N
G
K
P
A
G
Y
N
V
E
---
L
T
R
A
I
A
E
V
M
G
M
--------------------
T
--
V
---
E
F
R
L
G
-
A
-
W
S
E
M
F
S
A
L
K
S
G
R
V
D
V
L
Q
G
-
I
-
S
-
W
---
S
E
K
R
A
R
-----
Q
I
D
F
T
-----
P
P
H
T
I
V
Y
H
A
I
F
A
R
R
D
S
P
--
P
A
A
G
L
E
D
------
L
R
--
G
R
K
V
A
L
H
R
--
D
G
I
M
H
E
Y
L
A
E
R
----
G
---
Y
G
K
D
L
V
L
-
T
P
T
--
P
A
D
A
L
R
L
L
A
A
G
G
C
D
Y
A
V
V
A
M
V
P
G
M
Y
I
-
I
R
E
N
-
R
L
T
-
N
L
V
P
V
A
-----
R
-
S
-----
I
-----
A
A
Q
---
R
Y
G
Y
A
V
R
Q
G
---
D
A
E
L
L
A
R
-
F
S
E
G
L
A
I
L
R
K
T
G
Q
Y
E
A
I
R
A
K
W
----
L
G
V
L
E
---
28
HHSearch
79.72
20%
-77
- C4 -
2YLN
10
?
A:
[54-279]
------------------
N
N
K
G
T
---------
V
T
V
G
T
-
E
G
T
Y
A
P
F
T
Y
H
D
K----
D
G
K
L
T
G
Y
D
V
E
---
V
T
R
A
V
A
E
K
L
G
V
--------------------
K
--
V
---
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
F
D
V
V
A
N
-
Q
-
V
-
G
LTS
P
E
R
Q
-
A
-----
T
F
D
K
S
-----
E
P
Y
S
W
S
G
A
V
L
V
A
H
N
D
S
N
---
I
K
S
I
A
D
------
I
K
--
G
V
K
T
A
Q
S
L
--
T
S
N
Y
G
E
K
A
K
----
A
A
G
-----
A
Q
L
V
P
-
V
D
G
--
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
D
Y
-
L
K
K
N
P
N
A
G
V
K
I
V
W
S
A
-----
P
-
A
-----
D
-----
E
K
V
---
G
S
G
L
I
V
N
K
G
---
N
D
E
A
V
A
K
-
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
----
F
G
K
D
I
---
32
HHSearch
78.08
17%
-72
- C4 -
3VV5
1
?
A:
[32-255]
-----------------
I
K
R
S
G
E
---------
I
R
I
G
T
-
E
G
A
F
P
P
F
N
Y
F
D
E----
R
N
Q
L
T
G
F
E
V
D
---
L
G
N
A
I
A
E
R
L
G
L
--------------------
K
--
P
---
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
Q
G
R
F
D
F
V
I
A
-
S
-
H
G
I
---
T
E
E
R
A
R
-----
A
V
D
F
T
-----
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
G
G
----
P
R
T
A
K
D
------
L
Q
--
G
K
V
V
G
V
Q
V
--
G
T
T
Y
M
E
A
A
Q
K
I
---
P
G
-----
I
K
E
V
R
T
Y
Q
R
--
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
E
A
-
I
K
E
R
-
K
L
E
N
T
L
Q
V
-
G
-----
E
-
L
-----
V
-----
F
Q
E
---
R
V
A
M
A
V
A
K
G
---
N
K
S
L
L
D
A
-
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
----
F
G
E
D
V
---
2
PsiBlast_PDB
77.85
23%
-66
- C4 -
3ZSF
-
?
A:
[72-267]
----------------------------------------------------------
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
G
---
V
--------------------
K
--
V
---
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
F
D
V
V
A
N
-
Q
-
V
-
G
---
L
----
T
S
P
E
R
Q
A
T
F
D
K
----
S
E
P
Y
S
W
S
G
A
V
L
V
A
H
N
D
S
N
-
I
K
S
I
A
D
I
------------
K
G
V
K
T
A
Q
--
S
L
T
S
N
Y
G
E
K
A
K
A
A
G
A
-----
Q
L
V
P
V
D
G
-----
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
D
Y
-
L
K
K
N
P
N
A
G
V
K
I
V
W
S
A
-------------
P
-----
A
D
E
---
K
V
G
S
G
L
I
V
N
K
G
N
-
D
E
A
V
A
K
-
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
----
F
G
K
D
I
---
21
HHSearch
76.96
17%
-74
- C4 -
1LST
1
ARGT_SALTY
A:
[2-233]
-------------------
L
P
Q
T
---------
V
R
I
G
T
-
D
T
T
Y
A
P
F
S
S
K
D
A----
K
G
E
F
I
G
F
D
I
D
---
L
G
N
E
M
C
K
R
M
Q
V
--------------------
K
--
C
---
T
W
V
A
S
-
D
-
F
D
A
L
I
P
S
L
K
A
K
K
I
D
A
I
I
S
S
L
-
S
-
I
---
T
D
K
R
Q
Q
-----
E
I
A
F
S
-----
D
K
L
Y
A
A
D
S
R
L
I
A
A
K
G
S
P
-
I
-
Q
P
T
L
E
S
------
L
K
--
G
K
H
V
G
V
L
Q
--
G
S
T
Q
E
A
Y
A
N
D
N
W
R
T
K
G
-----
V
D
V
V
A
-
Y
A
N
--
Q
D
L
I
Y
S
D
L
T
A
G
R
L
D
A
A
L
Q
D
E
V
A
A
S
E
G
F
L
K
Q
-
P
A
G
-
K
E
Y
A
F
A
G
-----
P
-
S
VKDKK
Y
-----
F
G
D
---
G
T
G
V
G
L
R
K
D
---
D
T
E
L
K
A
A
-
F
D
K
A
L
T
E
L
R
Q
D
G
T
Y
D
K
M
A
K
K
Y
----
F
D
F
N
V
---
3
PsiBlast_PDB
76.48
20%
-58
- C4 -
4KR5
5
?
A:
[20-227]
----------------------
P
---------
F
E
F
Q
N
-
D
-
D
--------------
K
Q
F
T
G
I
D
V
D
---
L
L
N
A
I
A
K
---
N
--------------------
Q
--
G
F
K
L
K
W
N
F
I
-
G
-
F
Q
A
A
V
D
S
V
Q
S
G
H
A
D
G
M
M
S
-
G
-
M
-
S
---
I
----
T
-----
D
A
R
-------
K
Q
V
F
D
Y
G
S
P
Y
Y
S
S
N
L
T
I
-
A
T
S
S
T
D
D
S
IKSWKD
L
K
--
G
K
T
L
G
A
K
N
--
G
---
T
A
S
F
D
Y
L
N
A
H
A
K
E
Y
G
Y
T
V
K
T
F
T
D
A
T
T
--
M
Y
S
S
L
N
N
---
G
S
I
N
A
L
M
D
D
E
P
V
I
K
Y
A
-
I
K
Q
G
Q
K
F
A
T
P
I
K
--------
P
-
I
-----
P
-----
D
G
Q
Y
G
F
A
V
K
K
G
S
N
P
E
L
I
E
M
-------
F
N
N
G
L
A
N
L
R
A
N
G
E
Y
D
K
I
I
D
K
Y
----
L
E
------
36
HHSearch
76.29
17%
-87
- C4 -
3TQL
2
?
A:
[2-227]
---------------------
D
T
---------
I
K
F
A
T
-
E
A
T
Y
P
P
Y
V
Y
M
G
------
G
Q
V
E
G
F
G
A
D
---
I
V
K
A
V
C
K
Q
M
Q
A
--------------------
V
--
C
---
T
I
S
N
Q
-
P
-
W
D
S
L
I
P
S
L
K
L
G
K
F
D
A
L
F
G
-
G
M
N
-
I
---
T
T
A
R
Q
K
-----
E
V
D
F
T
-----
D
P
Y
Y
T
N
S
V
S
F
I
A
D
K
N
T
P
-
L
-
T
L
S
K
Q
G
------
L
K
--
G
K
I
I
G
V
Q
G
--
G
T
T
F
D
S
Y
L
Q
D
S
F
G
--
N
----
S
I
T
I
Q
R
-
Y
P
S
--
E
E
D
A
L
M
D
L
T
S
G
R
V
D
A
V
V
G
D
T
P
L
I
K
Q
W
-
L
K
Q
N
-
G
R
R
-
E
Y
V
L
I
G
-----
K
-
P
-----
V
NDPNY
F
G
K
---
G
V
G
I
A
V
K
K
G
---
N
Q
A
L
L
L
K
-
L
N
K
A
L
A
A
I
K
A
N
G
V
Y
A
A
I
V
Q
K
Y
----
F
-------
30
HHSearch
75.06
15%
-70
- C4 -
2Y7I
7
?
A:
[3-228]
------------------
V
S
A
R
T
---------
L
H
F
G
T
-
S
A
T
Y
A
P
Y
E
F
V
D
A----
D
N
K
I
V
G
F
D
I
D
---
V
A
N
A
V
C
K
E
M
Q
A
--------------------
E
--
C
---
S
F
T
N
Q
-
S
-
F
D
S
L
I
P
S
L
R
F
K
K
F
D
A
V
I
A
-
G
M
D
-
M
---
T
P
K
R
E
Q
-----
Q
V
S
F
S
-----
Q
P
Y
Y
E
G
L
S
A
V
V
V
T
R
K
G
A
---
Y
H
T
F
A
D
------
L
K
--
G
K
K
V
G
L
E
N
--
G
T
T
H
Q
R
Y
L
Q
D
K
Q
Q
-------
A
I
T
P
V
A
-
Y
D
S
--
Y
L
N
A
F
T
D
L
K
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
K
W
-
L
K
N
N
P
D
----
Y
A
I
M
D
E
R
A
S
D
P
-
D
-----
Y
-----
Y
G
K
---
G
L
G
I
A
V
R
K
D
---
N
D
A
L
L
Q
E
-
I
N
A
A
L
D
K
V
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
----
F
T
------
27
HHSearch
74.59
17%
-71
- C4 -
2YJP
10
?
A:
[52-278]
------------------
K
E
K
G
V
---------
I
R
I
G
V
-
F
G
D
K
P
P
F
G
Y
V
D
A----
N
G
K
N
Q
G
F
D
V
E
---
I
A
K
D
L
A
K
D
--
L
LGSPD---------------
K
--
V
---
E
F
V
L
T
-
E
-
A
A
N
R
V
E
Y
V
R
S
G
K
V
D
L
I
L
A
N
F
-
T
-
Q
---
T
P
E
R
A
E
-----
A
V
D
F
A
-----
D
P
Y
M
K
V
A
L
G
V
V
S
P
K
N
K
P
---
I
T
D
M
A
Q
------
L
K
--
D
Q
T
L
L
V
N
K
--
G
T
T
A
D
A
F
F
T
K
S
H
P
--
E
-----
V
K
L
L
K
-
F
D
Q
--
N
T
E
T
F
D
A
L
K
D
G
R
G
V
A
L
A
H
D
N
A
L
L
W
A
W
-
A
K
E
N
P
----
N
F
E
V
A
I
-----
G
N
L
-----
G
-----
P
A
E
---
F
I
A
P
A
V
Q
K
G
---
N
A
D
L
L
N
W
-
V
N
G
E
I
A
A
M
K
K
D
G
R
L
K
A
A
Y
E
K
T
----
L
L
P
V
Y
---
42
Fugue
74.22
16%
-65
- C4 -
1HSL
6
HISJ_ECOLI
A:
[1-238]
-
A
I
P
Q
K
I
R
I
G
T
D
P
T
Y
A
------
P
---------
F
E
S
K
N
-
A
-
Q
G
--------------
E
L
V
G
F
D
I
D
---
L
A
K
E
L
C
K
---
R
I
N
T
-----------------
Q
--
C
---
T
F
V
E
N
-
P
-
L
D
A
L
I
P
S
L
K
A
K
K
I
D
A
I
M
S
-
S
-
L
-
S
---
I
----
T
-----
E
K
R
Q
Q
E
I
A
F
T
D
K
L
Y
A
A
D
S
R
L
V
V
A
K
N
S
-D
I
Q
P
-
T
V
A
S
------
L
K
--
G
K
R
V
G
V
L
Q
--
G
---
T
T
Q
E
T
F
G
N
E
H
W
A
P
K
G
I
E
I
V
S
Y
Q
G
Q
D
N
--
I
Y
S
D
L
T
A
---
G
R
I
D
A
A
F
Q
D
E
V
A
A
S
E
G
-
F
L
K
Q
P
V
G
K
D
Y
K
F
G
G
P
-----
A
-
V
-----
K
-----
D
E
K
---
L
F
G
V
G
T
G
M
G
L
R
K
E
D
N
E
L
R
E
A
L
N
K
A
F
A
E
M
R
A
D
G
T
Y
E
K
L
A
K
K
Y
FDFD
V
Y
G
G
----
37
HHSearch
73.89
14%
-79
- C4 -
2PYY
1
?
A:
[4-223]
----------------------
P
---------
L
L
V
A
T
-
R
-
V
I
P
P
F
V
L
S
N
--------
L
S
G
F
S
I
D
---
L
W
R
S
I
A
T
Q
I
G
I
--------------------
E
--
S
---
K
L
I
E
Y
S
S
-
V
P
E
L
I
S
A
I
K
D
N
K
V
N
L
G
I
A
-
A
I
S
-
I
---
T
A
E
R
E
Q
-----
N
F
D
F
S
-----
L
P
I
F
A
S
G
L
Q
I
M
V
R
N
----
G
D
I
R
S
I
D
D
------
L
P
--
G
K
V
V
A
T
T
A
--
G
S
T
A
A
T
Y
L
R
E
----
H
H
-----
I
S
V
L
E
-
V
P
K
--
I
E
E
A
Y
K
A
L
Q
T
K
K
A
D
A
V
V
F
D
A
P
V
L
L
F
Y
-
A
A
N
E
-
G
K
-
G
K
V
E
I
V
G
-----
S
-
I
-----
L
-----
R
E
E
---
S
Y
G
I
I
L
P
N
N
----
S
P
Y
R
K
P
-
I
N
Q
A
L
L
N
L
K
E
N
G
T
Y
Q
S
L
Y
D
K
W
----
F
D
P
-----
39
HHSearch
72.82
15%
-71
* C4 *
3K4U
1
?
A:
[3-230]
-------------------
L
R
G
E
---------
L
R
V
G
L
-
E
P
G
Y
L
P
F
E
M
K
D
K----
K
G
N
V
I
G
F
D
V
D
---
L
A
R
E
M
A
K
A
M
G
V
--------------------
K
--
L
---
K
L
V
P
T
-
S
-
W
D
G
L
I
P
G
L
V
T
E
K
F
D
I
I
I
S
-
G
M
T
-
I
---
S
Q
E
R
N
L
-----
R
V
N
F
V
-----
E
P
Y
I
V
V
G
Q
S
L
L
V
K
K
G
L
E
-
K
G
V
K
S
Y
K
D
------
L
D
--
K
P
E
L
T
L
V
T
K
F
G
V
S
A
E
Y
A
A
K
R
L
F
K
-------
N
A
K
L
K
T
-
Y
D
T
--
E
A
E
A
V
Q
E
V
L
N
G
K
A
D
M
F
I
F
D
L
P
F
N
V
A
F
-
M
A
Q
K
-
G
Q
-
G
Y
L
V
H
L
D
-----
T
-
S
-----
L
-----
T
Y
E
---
P
L
G
W
A
I
K
K
G
---
D
P
D
F
L
N
W
-
L
N
H
F
L
A
Q
I
K
H
D
G
S
Y
D
E
L
Y
E
R
W
----
F
V
D
T
K
---
41
Fugue
72.33
13%
-71
- C4 -
1PB7
1
A:
[4-292]
----
T
R
L
K
I
V
T
I
H
Q
E
P
F
V
Y
V
K
P
T
M
SDGTC
K
E
E
F
T
V
N
G
-
D
-
P
V
K
K
V
I
C
T
G
PNH
T
V
P
Q
C
C
Y
G
F
C
I
D
---
L
L
I
K
L
A
R
---
T
M
N
F
T
Y
E
V
H
L
VADGKF
G
T
Q
E
R
V
--
N
---
N
S
N
K
K
-
E
-
W
N
G
M
M
G
E
L
L
S
G
Q
A
D
M
I
V
A
-
P
-
L
-
T
---
I
----
N
-----
N
E
R
A
Q
Y
I
E
F
S
K
P
F
K
Y
Q
G
L
T
I
L
V
K
K
G
T
R
-
I
T
G
I
N
D
P
R
------
L
R
--
N
P
S
D
K
F
I
Y
--
A
T
V
K
Q
S
S
V
D
I
Y
F
R
R
Q
V
E
L
S
T
M
Y
R
H
M
E
K
H
N
Y
ES
A
A
E
A
I
Q
A
V
R
D
N
K
L
H
A
F
I
W
D
S
A
V
L
E
F
E
-
A
S
Q
K
C
D
----
L
V
T
T
G
-----
E
-
L
-----
F
-----
F
R
S
---
G
F
G
I
G
M
R
K
D
----
S
P
W
K
Q
N
-
V
S
L
S
I
L
K
S
H
E
N
G
F
M
E
D
L
D
K
T
W
----
V
R
Y
Q
E
CDS
40
HHSearch
71.07
15%
-74
- C4 -
3MPK
4
A:
[28-251]
-----------------
M
A
D
H
P
V
---------
V
K
V
A
V
-
L
N
L
F
A
P
F
T
L
F
R
T----
D
E
Q
F
G
G
I
S
A
A
---
V
L
Q
L
L
Q
L
R
T
G
L
--------------------
D
--
F
---
E
I
I
G
V
-
D
T
V
E
E
L
I
A
K
L
R
S
G
E
A
D
M
A
G
A
-
L
-
F
-
V
---
N
SARE
S
-----
F
L
S
F
S
-----
R
P
Y
V
R
N
G
M
V
I
V
T
R
Q
D
P
D
--
A
P
V
D
A
D
H
------
L
D
--
G
R
T
V
A
L
V
R
--
N
S
A
A
I
P
L
L
Q
R
R
Y
P
Q
-------
A
K
V
V
T
-
A
D
N
--
P
S
E
A
M
L
M
V
A
N
G
Q
A
D
A
V
V
Q
T
Q
I
S
A
S
Y
Y
-
V
N
R
Y
-
F
A
-
G
K
L
R
I
A
S
-----
A
L
D
-----
L
-----
P
P
A
---
E
I
A
L
A
T
T
R
G
---
Q
T
E
L
M
S
I
-
L
N
K
A
L
Y
S
I
S
N
-
D
E
L
A
S
I
I
S
R
W
----
R
-------
31
HHSearch
68.98
13%
-74
- C4 -
1II5
1
?
A:
[3-226]
--------------------
A
M
A
---------
L
K
V
G
V
-
V
-
G
N
P
P
F
V
F
Y
G
-------
A
F
T
G
I
S
L
D
---
V
W
R
A
V
A
E
S
Q
K
W
--------------------
N
--
S
---
E
Y
V
R
Q
N
S
-
I
S
A
G
I
T
A
V
A
E
G
E
L
D
I
L
I
G
P
I
-
S
-
V
---
T
P
E
R
-
A
A
IE--
G
I
T
F
T
-----
Q
P
Y
F
S
S
G
I
G
L
L
I
P
G
T
A
T
-
P
L
F
R
S
V
G
D
------
L
K
--
N
K
E
V
A
V
V
R
--
D
T
T
A
V
D
W
A
N
F
----
Y
Q
-----
A
D
V
R
E
-
T
N
N
--
L
T
A
A
I
T
L
L
Q
K
K
Q
V
E
A
V
M
F
D
R
P
A
L
I
Y
Y
-
T
R
Q
N
P
N
--
L
N
L
E
V
T
E
-----
I
-
R
-----
V
-----
S
L
E
---
P
Y
G
F
V
L
K
E
N
----
S
P
L
Q
K
T
-
I
N
V
E
M
L
N
L
L
Y
S
R
V
I
A
E
F
T
E
R
W
----
L
G
------
23
HHSearch
68.78
13%
-67
- C4 -
2V25
3
PEB1A_CAMJE
A:
[34-258]
-----------------
I
K
S
K
G
Q
---------
L
I
V
G
V
K
N
-
D
V
P
H
Y
A
L
L
D
QA---
T
G
E
I
K
G
F
E
V
D
---
V
A
K
L
L
A
K
S
--
I
LGDDK---------------
K
--
I
---
K
L
V
A
V
-
N
-
A
K
T
R
G
P
L
L
D
N
G
S
V
D
A
V
I
A
-
T
F
T
-
I
---
T
P
E
R
K
R
-----
I
Y
N
F
S
-----
E
P
Y
Y
Q
D
A
I
G
L
L
V
L
K
E
K
K
---
Y
K
S
L
A
D
------
M
K
--
G
A
N
I
G
V
A
Q
--
A
A
T
T
K
K
A
I
G
E
A
A
K
K
I
G
I
---
D
V
K
F
S
E
-
F
P
D
--
Y
P
S
I
K
A
A
L
D
A
K
R
V
D
A
F
S
V
D
K
S
I
L
L
G
Y
-
V
D
D
------
K
S
E
I
L
P
-----
D
-
S
-----
F
-----
E
P
Q
---
S
Y
G
I
V
T
K
K
D
---
D
P
A
F
A
K
Y
-
V
D
D
F
V
K
E
H
K
N
--
E
I
D
A
L
A
K
K
W
----
G
L
------
29
HHSearch
68.77
11%
-74
- C4 -
2VHA
2
?
A:
[12-249]
----------------
K
I
A
K
N
G
V
---------
I
V
V
G
H
-
R
E
S
S
V
P
F
S
Y
Y
D
N----
Q
Q
K
V
V
G
Y
S
Q
D
---
Y
S
N
A
I
V
E
A
--
V
K
K
K
L
NKP-------------
D
L
Q
V
---
K
L
I
P
I
-
T
-
S
Q
N
R
I
P
L
L
Q
N
G
T
F
D
F
E
C
G
-
S
T
T
-
N
---
N
V
E
R
Q
K
-----
Q
A
A
F
S
-----
D
T
I
F
V
V
G
T
R
L
L
T
K
K
G
G
D
---
I
K
D
F
A
D
------
L
K
--
G
K
A
V
V
V
T
S
--
G
T
T
S
E
V
L
L
N
K
L
N
E
E
Q
K
---
M
N
M
R
I
I
S
-
A
K
D
--
H
G
D
S
F
R
T
L
E
S
G
R
A
V
A
F
M
M
D
D
A
L
L
A
G
E
-
R
A
K
A
-
K
K
P
D
N
W
D
I
V
G
-----
K
-
P
-----
Q
-----
S
Q
E
---
A
Y
G
C
M
L
R
K
D
---
D
P
Q
F
K
K
L
-
M
D
D
T
I
A
Q
V
Q
T
S
G
E
A
E
K
W
F
D
K
W
----
F
K
N
P
I
---
26
HHSearch
67.75
14%
-67
- C4 -
1WDN
1
GLNH_ECOLI
A:
[4-224]
----------------------
K
---------
L
V
V
A
T
-
D
T
A
F
V
P
F
E
F
K
Q
-----
G
D
L
Y
V
G
F
D
V
D
---
L
W
A
A
I
A
K
E
L
K
L
--------------------
D
--
Y
---
E
L
K
P
M
-
D
-
F
S
G
I
I
P
A
L
Q
T
K
N
V
D
L
A
L
A
G
I
-
T
-
I
---
T
DERK
K
-----
A
I
D
F
S
-----
D
G
Y
Y
K
S
G
L
L
V
M
V
K
A
N
N
N
--
D
V
K
S
V
K
D
------
L
D
--
G
K
V
V
A
V
K
S
--
G
T
G
S
V
D
Y
A
K
A
N
I
K
-------
T
K
D
L
R
Q
-
F
P
N
--
I
D
N
A
Y
M
E
L
G
T
N
R
A
D
A
V
L
H
D
T
P
N
I
L
Y
F
-
I
K
T
A
-
G
N
-
G
Q
F
K
A
V
G
-----
D
-
S
-----
L
-----
E
A
Q
---
Q
Y
G
I
A
F
P
K
G
---
S
D
E
L
R
D
K
-
V
N
G
A
L
K
T
L
R
E
N
G
T
Y
N
E
I
Y
K
K
W
----
F
G
T
E
P
---
35
HHSearch
67.69
15%
-67
- C4 -
3KBR
10
PHEC_PSEAE
A:
[10-236]
----------------
R
I
L
E
S
G
V
---------
L
R
V
A
T
-
T
G
D
Y
K
P
F
S
Y
R
T
E----
E
G
G
Y
A
G
F
D
V
D
---
M
A
Q
R
L
A
E
S
L
G
A
--------------------
K
--
L
---
V
V
V
P
T
-
S
-
W
P
N
L
M
R
D
F
A
D
D
R
F
D
I
A
M
S
-
G
I
S
-
I
---
N
L
E
R
Q
R
-----
Q
A
Y
F
S
-----
I
P
Y
L
R
D
G
K
T
P
I
T
L
C
S
E
E
-
A
R
F
Q
T
L
E
Q
------
I
D
QP
G
V
T
A
I
V
N
P
--
G
G
T
N
E
K
F
A
R
A
N
L
K
K
-------
A
R
I
L
V
-
H
P
D
--
N
V
T
I
F
Q
Q
I
V
D
G
K
A
D
L
M
M
T
D
A
I
E
A
R
L
Q
-
S
R
L
H
P
E
L
---
C
A
V
H
P
-----
Q
-
P
-----
F
-----
D
F
A
---
E
K
A
Y
L
L
P
R
D
----
E
A
F
K
R
Y
-
V
D
Q
W
L
H
I
A
E
Q
S
G
L
L
R
Q
R
M
E
H
W
----
L
-------