@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0173: (2015-11-29 )
MKSFCVKAPAKINLFLHVVEKKETGYHLIEGLFVFANLSNFLEIKVGEKDFRYDNPIVEFVNSELKISNKYNTVMRAVNLLLRHAPVRTKVTVKVVKNIPTSAGLGSGSSDAGAVIRTLGKLWKIDRPILNEIALSVGADVPASIDSKPVLVRGIGEELCYINKFSLPTNIVLAKPKKKFLSTPEVFSKYGGNFSKPIEWRDDTEKDLLKLLKETENDLQEIAISLVPEIRDVILALESQEGSILSRMSGSGVTCFGIFDSEENAKTAAVNIREKQPEWWVCDAQLIV
Atome Classification :
(20 SA)
.........10........20........30........40.....-...-50........60.......-.70---........80....------.------...90........100.......110.......120.--.--..--...----130.......140.......150.......160---.......170--........180.--------------....---..190.....--------.---..200..------..-....210..-...-----...220.......230.......240.......250.......260.......270.......280......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKSFCVKA
P
A
K
I
N
L
F
L
H
V
V
EKKET
G
Y
H
L
I
E
G
L
F
V
F
ANLS
N
F
L
E
I
K
V-GEK-DFRYDN
P
I
V
E
F
VNS
E
L
K
IS-
N
K
Y
---
N
T
V
M
R
A
V
N
L
L
L
RHA------P------V
R
T
K
V
T
V
K
V
VKNIPTSAGLGSGSS
D
A
G
A
V
I
R
T
L
G
K
L
W--K--I
D
--
R
P
I
----
L
N
E
I
A
L
SVGADVPASIDSK
P
V
L
V
R
GIGEE
L
C
Y
I
---NKFSLPT
N
I
---
V
L
AK
P
K
K
KFLST--------------
P
E
V
F
---
S
KYG-GNFSK--------P---IEWR-DD------
T
E
-
K
D
L
L
K
-
L
L
K
-
E
T
E-----N
D
L
Q
E
I
A
I
S
L
V
P
E
I
R
D
V
I
L
A
LESQE
G
S
I
L
S
RMSGSG
V
T
C
F
G
I
FDSEENA
K
T
A
A
V
N
I
REKQP
E
W
W
V
CDAQLIV
15
PsiBlast_PDB
92.43
29%
-82
- C2 -
2V8P
5
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
16
PsiBlast_PDB
91.60
29%
-84
- C2 -
2VF3
6
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
22
HHSearch
91.33
29%
-83
- C2 -
1UEK
-
ISPE_THET8
A:
[1-263]
---
M
E
R
L
A
P
A
K
V
N
L
G
L
S
V
R
F
R
R
E
D
G
Y
H
E
L
H
T
L
F
A
P
F
S
L
A
D
R
L
V
V
E
P
-
V
S
S
-
G
L
H
------
F
------
Q
G
P
Y
G
R
E
---
N
L
A
Y
R
A
A
S
L
Y
L
E
A
A
------
G
------
Q
P
G
G
V
R
I
L
L
E
K
R
I
P
E
G
A
G
L
G
G
G
S
S
D
A
A
Q
V
L
L
A
L
Q
A
L
Y
--
P
--
A
---
E
V
D
----
L
F
A
L
A
R
T
L
G
A
D
V
P
F
F
L
L
G
R
G
A
E
A
R
G
V
G
E
R
L
K
P
L
---
A
-
L
P
-
P
V
P
A
---
V
V
F
F
P
-
G
L
R
V
P
T
--------------
P
L
V
Y
---
R
A
V
R
-
P
E
D
F
G
P-------
D
LP
V
E
A
I
L
E
A
L
------
A
R
-
G
E
E
P
P
-
Y
W
N
-
S
L
---------
E
G
P
A
F
R
L
F
P
E
L
K
E
V
R
G
R
M
R
A
-
L
G
L
R
G
V
L
M
S
G
S
G
S
A
F
F
G
L
A
E
G
P
D
H
A
R
R
A
A
E
A
L
R
A
W
G
R
A
W
A
G
T
L
G
G
G
--
12
PsiBlast_PDB
91.27
29%
-83
- C2 -
2V2V
9
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
14
PsiBlast_PDB
91.15
29%
-83
- C2 -
2V34
7
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
24
HHSearch
91.01
30%
-95
- C2 -
2WW4
2
ISPE_ECOLI
A:
[1-263]
-
M
R
T
Q
W
P
S
P
A
K
L
N
L
F
L
Y
I
T
G
Q
R
A
D
G
Y
H
T
L
Q
T
L
F
Q
F
L
D
Y
G
D
T
I
S
I
E
L
-
R
D
D
G
D
I
R
----
L
L
T
P
V
---
E
G
V
E
-
H
E
D
---
N
L
I
V
R
A
A
R
L
L
M
K
T
A
------
A
D
S
GRLP
T
G
S
G
A
N
I
S
I
D
K
R
L
P
M
G
G
G
L
G
G
G
S
S
N
A
A
T
V
L
V
A
L
N
H
L
W
--
Q
--
C
G
LS
M
D
E
----
L
A
E
M
G
L
T
L
G
A
D
V
P
V
F
V
R
G
H
A
A
F
A
E
G
V
G
E
I
L
T
P
V
---
D
-
P
P
-
E
K
W
Y
---
L
V
A
H
P
-
G
V
S
I
P
T
--------------
P
V
I
F
---
K
D
P
E
-
L
P
R
N
T
--------
P
-----
K
R
-
S
------------
I
E
T
-
L
L
K
C
E
F
S
-----
N
D
C
E
V
I
A
R
K
R
F
R
E
V
D
A
V
L
S
W
L
L
E
--
Y
-
A
P
S
R
L
T
G
T
G
A
C
V
F
A
E
F
D
T
E
S
E
A
R
Q
V
L
E
Q
A
P
E
W
L
N
G
F
V
A
K
G
V
N
L
S
P
11
PsiBlast_PDB
90.75
29%
-85
- C2 -
2V2Q
8
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
6
PsiBlast_PDB
90.52
30%
-99
- C2 -
1UEK
-
ISPE_THET8
A:
[5-246]
-------
A
P
A
K
V
N
L
G
L
S
V
R
F
R
R
E
D
G
Y
H
E
L
H
T
L
F
A
P
F
S
L
A
D
R
L
----------------
V
V
E
P
V
S
S
G
L
H
F
Q
-
G
P
Y
GRE
N
L
A
Y
R
A
A
S
L
Y
L
E
A
A
------
G
------
Q
P
G
G
V
R
I
L
L
E
K
R
I
P
E
G
A
G
L
G
G
G
S
S
D
A
A
Q
V
L
L
A
L
Q
A
L
Y
PA
E
--
V
D
---------
L
F
A
L
A
R
T
L
G
A
D
V
P
F
F
L
L
G
R
G
A
E
A
R
G
V
G
E
R
L
K
P
L
---
A
L
P
P
V
P
A
V
V
---
F
F
P
G
L
R
---
V
P
T
--------------
P
L
V
Y
---
R
A
V
------
R
--------
P
---
E
D
F
G
-
P
D
------
L
P
V
E
A
I
L
E
-
A
L
A
-
R
G
E
EPPYW
N
S
L
E
G
P
A
F
R
L
F
P
E
L
K
E
V
R
G
R
M
R
A
L
-
G
L
R
G
V
L
M
S
G
S
G
S
A
F
F
G
L
A
E
G
P
D
H
A
R
R
A
A
E
A
L
R
A
W
G
R
A
W
A
G
T
L
G
G
G
--
13
PsiBlast_PDB
90.43
29%
-82
- C2 -
2V2Z
5
ISPE_AQUAE
A:
[7-271]
-----
V
L
S
P
A
K
I
N
L
G
L
W
V
L
G
R
L
P
S
G
Y
H
E
I
--
L
T
L
Y
Q
E
I
P
F
Y
D
E
I
Y
I
-
R
E
G
-
V
L
R
--------
V
E
T
N
I
G
I
P
-
Q
E
E
---
N
L
V
Y
K
G
L
R
E
F
E
R
I
T
------
G
------
I
E
I
N
Y
S
I
F
I
Q
K
N
I
P
P
G
A
G
L
G
G
G
S
S
N
L
A
V
V
L
K
K
V
N
E
L
------
L
G
--
S
P
L
S
E
E
E
L
R
E
L
V
G
S
I
S
A
D
A
P
F
F
L
L
G
K
S
A
I
G
R
G
K
G
E
V
L
E
P
V
---
E
T
-
E
I
S
G
K
I
---
T
L
V
I
P
Q
V
S
S
-
S
T
--------------
G
R
V
Y
---
S
S
L
R
E
E
H
F
V
T
--------
P
---
E
Y
A
E
-
E
K
------
I
Q
-
R
I
I
S
G
-
E
V
E
-
E
I
E
-----
N
V
L
G
D
I
A
R
E
L
Y
P
E
I
N
E
V
Y
R
F
V
E
Y
L
--
G
F
K
P
F
V
S
G
S
G
S
T
V
Y
F
F
G
G
A
S
E
E
L
K
K
A
A
-----
K
M
R
G
W
K
V
V
E
L
E
L
--
45
Fugue
86.77
29%
-71
- C2 -
1UEK
-
ISPE_THET8
A:
[1-268]
---
M
E
R
L
A
P
A
K
V
N
L
G
L
S
V
R
F
R
R
E
D
G
Y
H
E
L
H
T
L
F
A
P
F
S
L
A
D
R
L
V
V
E
P
-
V
S
S
-
G
L
H
F
Q
G
P
Y
------------
G
R
E
---
N
L
A
Y
R
A
A
S
L
Y
L
E
A
A
------
G
------
Q
P
G
G
V
R
I
L
L
E
K
R
I
P
E
G
A
G
L
G
G
G
S
S
D
A
A
Q
V
L
L
A
L
Q
A
L
Y
--
P
--
A
E
--
V
D
-----
L
F
A
L
A
R
T
L
G
A
D
V
P
F
F
L
L
G
R
G
A
E
A
R
G
V
G
E
R
L
K
P
L
---
A
--
L
P
P
V
P
A
---
V
V
F
F
P
G
L
R
-
V
P
T
--------------
P
L
V
Y
---
R
A
V
R
-
P
E
D
F
G
--------
P
---
D
L
P
V
-
E
A
------
I
L
-
E
A
L
A
R
G
E
E
P
-
P
Y
W
-----
N
S
L
E
G
P
A
F
R
L
F
P
E
L
K
E
V
R
G
R
M
R
A
L
-
G
L
R
G
V
L
M
S
G
S
G
S
A
F
F
G
L
A
E
G
P
D
H
A
R
R
A
A
E
A
L
R
A
W
G
R
A
W
A
G
T
L
G
G
G
--
3
PsiBlast_PDB
85.20
28%
-67
- C2 -
4ED4
1
?
A:
[17-283]
--
A
V
T
V
R
A
P
G
K
V
N
L
Y
L
A
V
G
D
L
----
Y
H
E
L
T
T
V
F
H
A
V
S
L
A
D
--
D
V
T
V
-
R
D
A
-
D
V
L
S
I
D
V
V
G
Q
--
G
E
G
T
V
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
F
A
D
H
V
------
G
------
R
A
P
D
V
S
I
F
I
N
K
D
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
E
L
W
--
H
AG
V
P
--
R
R
D
----
L
H
H
L
A
A
Q
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
Q
L
A
T
V
-------
L
A
R
N
V
F
H
W
V
F
A
F
A
D
G
G
-
L
A
T
--------------
P
Q
V
F
K
E
I
D
R
L
R
-
E
N
G
D
P
--------
P
---
R
L
A
E
-
A
D
E
L
L
G
A
L
A
A
-
G
D
A
R
R
-
L
A
P
-
L
L
G
-----
N
E
L
Q
A
A
A
V
S
L
N
P
E
L
R
R
T
L
R
A
G
E
S
A
-
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
D
D
A
V
Q
V
S
A
E
L
A
G
A
G
V
C
R
T
V
R
V
A
S
G
P
V
2
PsiBlast_PDB
84.45
28%
-66
- C2 -
4DXL
3
?
A:
[17-283]
--
A
V
T
V
R
A
P
G
K
V
N
L
Y
L
A
V
G
D
L
R
D
D
G
Y
H
E
L
T
T
V
F
H
A
V
S
L
A
D
--
D
V
T
V
-
R
D
A
-
D
V
L
S
I
D
V
V
G
Q
--
G
E
G
T
V
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
F
A
D
H
V
------
G
------
R
A
P
D
V
S
I
F
I
N
K
D
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
E
L
W
--
H
AG
V
P
--
R
R
D
----
L
H
H
L
A
A
Q
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
Q
L
A
T
V
-------
L
A
R
N
V
F
H
W
V
F
A
F
A
D
G
G
-
L
A
T
--------------
P
Q
V
F
K
E
I
D
R
L
R
-
E
N
G
D
P
--------
P
---
R
L
A
E
-
A
D
E
L
L
G
A
L
A
A
-
G
D
A
R
R
-
L
A
P
-
L
L
G
-----
N
E
L
Q
A
A
A
V
S
L
N
P
E
L
R
R
T
L
R
A
G
E
S
A
-
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
D
D
A
V
Q
V
S
A
E
L
A
G
A
G
V
C
R
T
V
R
V
A
S
G
P
V
4
PsiBlast_PDB
84.37
28%
-67
- C2 -
4EMD
2
?
A:
[17-283]
--
A
V
T
V
R
A
P
G
K
V
N
L
Y
L
A
V
G
D
L
R
D
D
G
Y
H
E
L
T
T
V
F
H
A
V
S
L
A
D
--
D
V
T
V
-
R
D
A
-
D
V
L
S
I
D
V
V
G
Q
--
G
E
G
T
V
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
F
A
D
H
V
------
G
------
R
A
P
D
V
S
I
F
I
N
K
D
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
E
L
W
--
H
AG
V
P
--
R
R
D
----
L
H
H
L
A
A
Q
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
Q
L
A
T
V
-------
L
A
R
N
V
F
H
W
V
F
A
F
A
D
G
G
-
L
A
T
--------------
P
Q
V
F
K
E
I
D
R
L
R
-
E
N
G
D
P
--------
P
---
R
L
A
E
-
A
D
E
L
L
G
A
L
A
A
-
G
D
A
R
R
-
L
A
P
-
L
L
G
-----
N
E
L
Q
A
A
A
V
S
L
N
P
E
L
R
R
T
L
R
A
G
E
S
A
-
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
D
D
A
V
Q
V
S
A
E
L
A
G
A
G
V
C
R
T
V
R
V
A
S
G
P
V
5
PsiBlast_PDB
80.46
28%
-65
- C2 -
1OJ4
3
ISPE_ECOL6
A:
[7-264]
-------
S
P
A
K
L
N
L
F
L
Y
I
T
G
Q
R
A
D
G
Y
H
T
L
Q
T
L
F
Q
F
L
D
Y
G
D
T
I
S
I
E
L
R
D
D
G
-
D
I
R
L
L
T
P
V
E
-------
G
V
E
-
H
E
D
---
N
L
I
V
R
A
A
R
L
L
M
K
T
A
A
D
S
GRL
P
------
T
G
S
G
A
N
I
S
I
D
K
R
L
P
M
G
G
G
L
G
G
G
S
S
N
A
A
T
V
L
V
A
L
N
H
L
W
--
Q
CG
L
S
--
M
D
E
----
L
A
E
M
G
L
T
L
G
A
D
V
P
V
F
V
R
G
H
A
A
F
A
E
G
V
G
E
I
L
T
P
V
---
D
P
---
P
E
K
W
---
Y
L
V
A
H
P
G
V
S
I
P
T
--------------
P
V
I
-----------
F
K
D
--------
P
---
E
L
P
R
-
N
T
------
P
K
-
R
S
I
E
T
-
L
L
K
C
E
F
S
-----
N
D
C
E
V
I
A
R
K
R
F
R
E
V
-
D
A
V
L
S
W
L
L
E
Y
A
P
--
S
R
L
T
G
T
G
A
C
V
F
A
E
F
D
T
E
S
E
A
R
----
Q
V
L
E
Q
A
P
E
W
L
N
G
F
V
A
K
G
V
1
PsiBlast_PDB
78.83
28%
-71
- C2 -
2WW4
2
ISPE_ECOLI
A:
[7-264]
-------
S
P
A
K
L
N
L
F
L
Y
I
T
G
Q
R
A
D
G
Y
H
T
L
Q
T
L
F
Q
F
L
D
Y
G
D
T
I
S
I
E
L
R
D
D
G
-
D
I
R
L
L
T
P
V
E
-------
G
V
E
-
H
E
D
---
N
L
I
V
R
A
A
R
L
L
M
K
T
A
A
D
S
GRL
P
------
T
G
S
G
A
N
I
S
I
D
K
R
L
P
M
G
G
G
L
G
G
G
S
S
N
A
A
T
V
L
V
A
L
N
H
L
W
--
Q
--
C
G
--
L
S
M
D
E
--
L
A
E
M
G
L
T
L
G
A
D
V
P
V
F
V
R
G
H
A
A
F
A
E
G
V
G
E
I
L
T
P
V
---
D
P
---
P
E
K
W
---
Y
L
V
A
H
P
G
V
S
I
P
T
--------------
P
V
I
-----------
F
K
D
--------
P
---
E
L
P
R
-
N
T
------
P
K
-
R
S
I
E
T
-
L
L
K
C
E
F
S
-----
N
D
C
E
V
I
A
R
K
R
F
R
E
V
-
D
A
V
L
S
W
L
L
E
Y
A
P
--
S
R
L
T
G
T
G
A
C
V
F
A
E
F
D
T
E
S
E
A
R
----
Q
V
L
E
Q
A
P
E
W
L
N
G
F
V
A
K
G
V
10
PsiBlast_PDB
77.07
27%
-64
- C2 -
3PYG
1
ISPE_MYCTU
A:
[5-271]
--
S
V
T
V
R
V
P
G
K
V
N
L
Y
L
A
V
G
D
R
R
E
D
G
Y
H
--
E
L
T
T
V
F
H
A
V
S
L
V
D
E
V
T
V
-
R
N
A
-
D
V
L
S
L
E
L
V
G
E
--
G
A
D
Q
L
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
M
A
E
H
V
------
G
------
R
A
P
D
V
S
I
M
I
D
K
S
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
S
L
W
--
E
--
L
N
--
V
P
R
R
D
--
L
R
M
L
A
A
R
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
E
L
A
T
V
L
S
R
N
T
F
----
H
W
---
V
L
A
F
A
D
S
G
L
L
T
S
A
V
Y
N
E
L
D
R
L
R
E
V
GD
P
P
R
L
---
G
E
P
G
-
P
V
L
A
A
--------
L
---
A
A
G
D
-
P
D
------
Q
L
-
A
P
L
L
G
-------------
N
E
M
Q
A
A
A
V
S
L
D
P
A
L
A
R
A
L
R
A
-
G
V
E
A
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
S
S
A
I
D
V
G
A
Q
L
S
G
A
G
V
C
R
T
V
R
V
A
T
G
P
V
8
PsiBlast_PDB
76.30
27%
-63
- C2 -
3PYE
1
ISPE_MYCTU
A:
[5-271]
--
S
V
T
V
R
V
P
G
K
V
N
L
Y
L
A
V
G
D
R
R
E
D
G
Y
H
--
E
L
T
T
V
F
H
A
V
S
L
V
D
E
V
T
V
-
R
N
A
-
D
V
L
S
L
E
L
V
G
E
--
G
A
D
Q
L
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
M
A
E
H
V
------
G
------
R
A
P
D
V
S
I
M
I
D
K
S
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
S
L
W
--
E
--
L
N
--
V
P
R
R
D
--
L
R
M
L
A
A
R
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
E
L
A
T
V
L
S
R
N
T
F
----
H
W
---
V
L
A
F
A
D
S
G
L
L
T
S
A
V
Y
N
E
L
D
R
L
R
E
V
GD
P
P
R
L
---
G
E
P
G
-
P
V
L
A
A
--------
L
---
A
A
G
D
-
P
D
------
Q
L
-
A
P
L
L
G
-------------
N
E
M
Q
A
A
A
V
S
L
D
P
A
L
A
R
A
L
R
A
-
G
V
E
A
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
S
S
A
I
D
V
G
A
Q
L
S
G
A
G
V
C
R
T
V
R
V
A
T
G
P
V
21
HHSearch
74.93
26%
-68
- C2 -
3PYF
1
ISPE_MYCTU
A:
[5-282]
--
S
V
T
V
R
V
P
G
K
V
N
L
Y
L
A
V
G
D
R
R
E
D
G
Y
H
E
L
T
T
V
F
H
A
V
S
L
V
D
E
V
T
V
R
N
-
A
D
V
-
L
-
S
----
L
E
L
V
G
E
G
A
D
Q
L
P
T
D
E
R
---
N
L
A
W
Q
A
A
E
L
M
A
E
H
V
------
G
------
R
A
P
D
V
S
I
M
I
D
K
S
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
S
L
W
--
E
--
L
N
VP
R
R
D
----
L
R
M
L
A
A
R
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
E
L
A
T
V
---
L
S
R
N
-
T
F
H
W
---
V
L
A
F
A
-
D
S
G
L
L
T
--------------
S
A
V
Y
---
N
E
L
D
-
R
L
R
E
V
GD
P
P
R
L
G
E
P
---
G
P
V
L
A
A
L
------
A
A
-
G
D
P
D
Q
-
L
A
P
-
L
L
G
-----
N
E
M
Q
A
A
A
V
S
L
D
P
A
L
A
R
A
L
R
A
G
V
E
-
A
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
S
S
A
I
D
V
G
A
Q
L
S
G
A
G
V
C
R
T
V
R
V
A
T
G
P
V
9
PsiBlast_PDB
73.62
27%
-62
- C2 -
3PYF
1
ISPE_MYCTU
A:
[5-271]
--
S
V
T
V
R
V
P
G
K
V
N
L
Y
L
A
V
G
D
R
R
E
D
G
Y
H
--
E
L
T
T
V
F
H
A
V
S
L
V
D
E
V
T
V
-
R
N
A
-
D
V
L
S
L
E
L
V
G
E
--
G
A
D
Q
L
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
M
A
E
H
V
------
G
------
R
A
P
D
V
S
I
M
I
D
K
S
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
S
L
W
--
E
--
L
N
--
V
P
R
R
D
--
L
R
M
L
A
A
R
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
E
L
A
T
V
L
S
R
N
T
F
----
H
W
---
V
L
A
F
A
D
S
G
L
L
T
S
A
V
Y
N
E
L
D
R
L
R
E
V
GD
P
P
R
L
---
G
E
P
G
-
P
V
L
A
A
--------
L
---
A
A
G
D
-
P
D
------
Q
L
-
A
P
L
L
G
-------------
N
E
M
Q
A
A
A
V
S
L
D
P
A
L
A
R
A
L
R
A
-
G
V
E
A
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
S
S
A
I
D
V
G
A
Q
L
S
G
A
G
V
C
R
T
V
R
V
A
T
G
P
V
7
PsiBlast_PDB
72.91
27%
-62
- C2 -
3PYD
1
ISPE_MYCTU
A:
[5-271]
--
S
V
T
V
R
V
P
G
K
V
N
L
Y
L
A
V
G
D
R
R
E
D
G
Y
H
--
E
L
T
T
V
F
H
A
V
S
L
V
D
E
V
T
V
-
R
N
A
-
D
V
L
S
L
E
L
V
G
E
--
G
A
D
Q
L
P
T
-
D
E
R
---
N
L
A
W
Q
A
A
E
L
M
A
E
H
V
------
G
------
R
A
P
D
V
S
I
M
I
D
K
S
I
P
V
A
G
G
M
A
G
G
S
A
D
A
A
A
V
L
V
A
M
N
S
L
W
--
E
--
L
N
--
V
P
R
R
D
--
L
R
M
L
A
A
R
L
G
S
D
V
P
F
A
L
H
G
G
T
A
L
G
T
G
R
G
E
E
L
A
T
V
L
S
R
N
T
F
----
H
W
---
V
L
A
F
A
D
S
G
L
L
T
S
A
V
Y
N
E
L
D
R
L
R
E
V
GD
P
P
R
L
---
G
E
P
G
-
P
V
L
A
A
--------
L
---
A
A
G
D
-
P
D
------
Q
L
-
A
P
L
L
G
-------------
N
E
M
Q
A
A
A
V
S
L
D
P
A
L
A
R
A
L
R
A
-
G
V
E
A
G
A
L
A
G
I
V
S
G
S
G
P
T
C
A
F
L
C
T
S
A
S
S
A
I
D
V
G
A
Q
L
S
G
A
G
V
C
R
T
V
R
V
A
T
G
P
V