@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0580: (2015-12-02 )
MAVENEGVLLVLSSPSGAGKTTILERLLERSTNLVRSVSMTTRKPRPGEINGKDYFFVTKKEFHELCEAGQMLEYARVFENFYGIPKSFIEQNLSSGISVLLSIDWQGAFHLFELMREKVISVFILPPSMEELRLRLQKRNSDSASEIEHRLAEAQKEMSKRDKYDYVVINDDIDKSVEEISSILDKERLKRSGV
Atome Classification :
(32 SA)
......-...10........20.......-.30..--.-...--...40........50........60........70........80--..--......90........100.......110......-.---120.......130.......140.......150.......--160-..--..---.....170.......180.......190...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAVENE-
G
V
L
L
V
LSSPSGA
G
K
T
T
I
L
E
R
L
L
-
E
R
-
S
T
--
N
-
L
V
R
--
S
VSMTTRKPRPGEINGK
D
Y
F
F
V
T
K
K
E
F
H
E
L
C
E
A
G
Q
M
L
E
Y
A
R
V
F
E
N
--FY--GI
P
K
S
F
I
E
Q
N
L
S
S
G
I
S
V
L
L
S
IDWQ
G
A
F
H
L
F
E
L
M
R
E
-K---
V
I
S
V
F
ILPP
S
M
E
E
L
R
L
R
L
QKRNSD
S
A
S
E
I
E
H
R
L
A
E
A
Q
K
E
M
--
S
---KR--DK---Y
D
Y
V
V
INDD
I
D
K
S
V
E
E
I
S
S
I
L
D
K
E
R
L
K
RSGV
5
PsiBlast_PDB
94.56
44%
-115
- C5 -
2F3T
1
KGUA_ECOLI
A:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
22
PsiBlast_CBE
94.19
44%
-116
- C5 -
2F3T
1
KGUA_ECOLI
E:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
23
PsiBlast_CBE
94.05
44%
-118
- C5 -
2F3T
1
KGUA_ECOLI
B:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
---
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
3
PsiBlast_PDB
93.09
44%
-108
- C5 -
2ANC
-
KGUA_ECOLI
A:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
24
PsiBlast_CBE
93.05
44%
-113
- C5 -
2F3R
1
KGUA_ECOLI
B:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
----
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
21
PsiBlast_CBE
92.75
44%
-115
- C5 -
2F3T
1
KGUA_ECOLI
F:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
6
PsiBlast_PDB
92.05
44%
-106
- C5 -
1S96
2
KGUA_ECOLI
A:
[15-203]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
----
Q
Q
I
R
Q
-
K
M
PH
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
4
PsiBlast_PDB
91.58
44%
-113
- C5 -
2F3R
1
KGUA_ECOLI
A:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
----
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
25
PsiBlast_CBE
91.07
44%
-107
- C5 -
2AN9
3
KGUA_ECOLI
B:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
57
HHSearch
91.01
45%
-111
* C5 *
1S96
2
KGUA_ECOLI
A:
[15-201]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
--
L
-
Y
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
--
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
1
PsiBlast_PDB
90.55
44%
-109
- C5 -
2AN9
3
KGUA_ECOLI
A:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
2
PsiBlast_PDB
89.88
44%
-107
- C5 -
2ANB
2
KGUA_ECOLI
A:
[3-191]
-----
Q
-
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
-
Q
P
LY
D
-
T
Q
V
--
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
--
Y
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
-
P
-
H
---
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
--
S
---
H
Y
--
A
E
---
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
7
PsiBlast_PDB
88.18
42%
-109
- C5 -
3TR0
3
KGUA_COXBU
A:
[5-191]
----
N
K
-
A
N
L
F
I
I
S
A
P
S
G
A
G
K
T
S
L
V
R
A
L
V
-
K
A
-
L
A
--
E
-
I
K
I
--
S
I
S
H
T
T
R
P
K
R
P
G
D
Q
E
G
V
D
Y
F
F
I
D
E
T
R
F
Q
A
M
V
K
E
G
A
F
L
E
H
A
T
I
Y
E
R
--
H
Y
--
G
T
E
K
D
W
V
L
R
Q
L
K
A
G
R
D
V
L
L
E
I
D
W
Q
G
A
R
Q
I
R
E
L
F
-
P
-
P
---
A
L
S
I
F
I
L
P
P
S
I
E
A
L
R
E
R
L
I
K
R
R
Q
D
D
T
A
I
I
E
Q
R
L
A
L
A
R
E
E
M
--
A
---
H
Y
--
K
E
---
F
D
Y
L
V
V
N
D
N
F
D
Q
A
V
Q
N
L
I
H
I
I
S
A
E
R
L
Q
R
D
V
Q
46
HHSearch
87.90
34%
-123
- C5 -
1ZNW
-
KGUA_MYCTU
A:
[20-201]
-----
V
-
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
-
I
P
--
N
-
L
H
F
--
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
H
R
S
--
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
--
E
---
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
--
A
---
A
Q
--
G
D
---
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
---------
28
PsiBlast_CBE
87.31
40%
-107
- C5 -
4QRH
3
?
B:
[5-197]
---
D
N
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
L
E
H
L
-------------------
N
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
40
HHSearch
86.88
38%
-108
- C5 -
3TAU
3
KGUA_LISMO
A:
[5-193]
---
T
E
R
-
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
E
A
V
F
-
K
D
-
P
E
--
T
S
F
D
Y
--
S
I
S
M
T
T
R
L
P
R
E
G
E
Q
D
G
V
D
Y
Y
F
R
S
R
E
V
F
E
Q
A
I
K
D
G
K
M
L
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
L
E
Y
V
E
E
K
L
A
A
G
V
D
I
F
L
E
I
E
V
Q
G
A
M
Q
V
R
K
A
M
P
--
E
---
G
I
F
I
F
L
T
P
P
D
L
S
E
L
K
N
R
-------
S
M
E
V
V
E
E
R
M
E
T
A
K
K
E
I
--
E
---
M
M
--
A
S
---
Y
D
Y
A
V
V
N
D
V
V
A
N
A
V
Q
K
I
K
G
I
V
E
T
E
H
L
K
T
E
R
V
9
PsiBlast_PDB
86.26
40%
-122
- C5 -
2J41
1
KGUA_STAAC
A:
[4-194]
-----
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
---------------------------
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
8
PsiBlast_PDB
86.23
40%
-115
- C5 -
4QRH
1
?
A:
[6-197]
----
N
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
L
E
H
L
-------------------
N
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
29
PsiBlast_CBE
85.97
40%
-119
- C5 -
2J41
4
KGUA_STAAC
D:
[5-194]
------K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
------------------------
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
26
PsiBlast_CBE
85.46
40%
-109
- C5 -
4QRH
6
?
D:
[6-197]
----
N
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
L
E
H
L
--------------
I
Q
S
R
I
N
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
30
PsiBlast_CBE
85.17
40%
-115
- C5 -
2J41
3
KGUA_STAAC
C:
[5-194]
------K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
-------------------
Q
S
R
I
N
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
31
PsiBlast_CBE
85.01
40%
-116
- C5 -
2J41
3
KGUA_STAAC
B:
[5-194]
------K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
----------------------------
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
43
HHSearch
83.73
40%
-98
- C5 -
3TR0
3
KGUA_COXBU
A:
[5-191]
----
N
K
-
A
N
L
F
I
I
S
A
P
S
G
A
G
K
T
S
L
V
R
A
L
V
-
K
A
-
L
A
--
E
-
I
K
I
--
S
I
S
H
T
T
R
P
K
R
P
G
D
Q
E
G
V
D
Y
F
F
I
D
E
T
R
F
Q
A
M
V
K
E
G
A
F
L
E
H
A
T
I
Y
E
R
--
H
Y
--
G
T
E
K
D
W
V
L
R
Q
L
K
A
G
R
D
V
L
L
E
I
D
W
Q
G
A
R
Q
I
R
E
L
F
P
P
-
A
---
L
S
I
F
I
L
P
P
S
-
I
E
A
L
R
E
R
L
I
K
R
R
Q
D
D
T
A
I
I
E
Q
R
L
A
L
A
R
E
E
M
--
A
---
H
Y
--
K
E
---
F
D
Y
L
V
V
N
D
N
F
D
Q
A
V
Q
N
L
I
H
I
I
S
A
E
R
L
Q
R
D
V
Q
15
PsiBlast_PDB
82.50
37%
-111
- C5 -
1Z8F
2
KGUA_MYCTU
A:
[23-202]
-------
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
-
I
P
--
N
-
L
H
F
--
S
V
S
A
T
T
R
C
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
--
L
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
E
-
A
---
V
-
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
C
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
--
A
---
A
Q
--
G
D
---
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
G
--------
20
PsiBlast_PDB
82.35
36%
-82
- C5 -
1LVG
3
KGUA_MOUSE
A:
[7-194]
----------
V
V
L
S
G
P
S
G
A
G
K
S
T
L
L
K
K
L
F
-
Q
E
-
H
S
--
S
-
I
F
G
F
-
S
V
S
H
T
T
R
N
P
R
P
G
E
E
D
G
K
D
Y
Y
F
V
T
R
E
M
M
Q
R
D
I
A
A
G
D
F
I
E
H
A
E
F
S
G
N
--
L
Y
--
G
T
S
K
E
A
V
R
A
V
Q
A
M
N
R
I
C
V
L
D
V
D
L
Q
G
V
R
S
I
-
K
K
T
D
L
-
C
---
P
I
Y
I
F
V
Q
P
P
S
L
D
V
L
E
Q
R
L
R
L
R
N
T
E
T
E
E
S
L
A
K
R
L
A
A
A
R
T
D
M
--
E
---
S
S
--
K
E
PGL
F
D
L
V
I
I
N
D
D
L
D
K
A
Y
A
T
L
K
Q
A
L
S
E
E
I
K
K
A
Q
G
-
44
HHSearch
82.07
36%
-94
- C5 -
1LVG
3
KGUA_MOUSE
A:
[5-193]
--------
R
P
V
V
L
S
G
P
S
G
A
G
K
S
T
L
L
K
K
L
F
-
Q
E
-
H
S
--
S
I
F
G
F
--
S
V
S
H
T
T
R
N
P
R
P
G
E
E
D
G
K
D
Y
Y
F
V
T
R
E
M
M
Q
R
D
I
A
A
G
D
F
I
E
H
A
E
F
S
G
N
--
L
Y
--
G
T
S
K
E
A
V
R
A
V
Q
A
M
N
R
I
C
V
L
D
V
D
L
Q
G
V
R
S
I
K
K
T
D
L
--
C
---
P
I
Y
I
F
V
Q
P
P
S
L
D
V
L
E
Q
R
L
R
L
R
N
T
E
T
E
E
S
L
A
K
R
L
A
A
A
R
T
D
M
--
E
SSK
E
P
--
G
L
---
F
D
L
V
I
I
N
D
D
L
D
K
A
Y
A
T
L
K
Q
A
L
S
E
E
I
K
K
A
Q
G
-
10
PsiBlast_PDB
81.83
37%
-106
- C5 -
1S4Q
4
KGUA_MYCTU
A:
[23-202]
-------
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
-
I
P
--
N
-
L
H
F
--
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
--
L
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
E
-
A
---
V
-
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
--
A
---
A
Q
--
G
D
---
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
G
--------
27
PsiBlast_CBE
81.45
40%
-108
- C5 -
4QRH
4
?
C:
[6-197]
----
N
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
P
S
T
--
S
-
Y
K
Y
--
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
--
Y
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
D
-
A
---
L
F
-
I
F
L
A
P
P
S
L
E
H
L
------------------
I
N
E
A
R
K
E
V
--
E
---
M
M
--
N
L
---
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
18
PsiBlast_PDB
79.98
37%
-99
- C5 -
1GKY
3
KGUA_YEAST
A:
[4-186]
----------
I
V
I
S
G
P
S
G
T
G
K
S
T
L
L
K
K
L
F
A
E
Y
-
P
D
--
S
-
F
G
F
--
S
V
S
S
T
T
R
T
P
R
A
G
E
V
N
G
K
D
Y
N
F
V
S
V
D
E
F
K
S
M
I
K
N
N
E
F
I
E
W
A
Q
F
S
G
N
--
Y
Y
--
G
S
T
V
A
S
V
K
Q
V
S
K
S
G
K
T
C
I
L
D
I
D
M
Q
G
V
K
S
V
K
A
I
P
E
L
-
N
---
A
R
F
L
F
I
A
P
P
S
V
E
D
L
K
K
R
L
E
G
R
G
T
E
T
E
E
S
I
N
K
R
L
S
A
A
Q
A
E
L
A
Y
A
---
E
T
--
G
A
---
H
D
K
V
I
V
N
D
D
L
D
K
A
Y
K
E
L
K
D
F
I
F
A
E
K
------
41
HHSearch
79.73
32%
-87
- C5 -
2QOR
2
?
A:
[9-200]
---
M
A
R
-
I
P
P
L
V
V
C
G
P
S
G
V
G
K
G
T
L
I
K
K
V
L
-
S
E
-
F
P
S-
R
-
F
R
F
--
S
I
S
C
T
T
R
N
K
R
E
K
E
T
N
G
V
D
Y
Y
F
V
D
K
D
D
F
E
R
K
L
K
E
G
Q
F
L
E
F
D
K
Y
A
N
N
--
F
Y
--
G
T
L
K
S
E
Y
D
L
A
V
G
E
G
K
I
C
L
F
E
M
N
I
N
G
V
K
Q
L
K
E
S
K
H
I
Q
D
---
G
I
Y
I
F
V
K
P
P
S
I
D
I
L
L
G
R
L
K
N
R
N
T
E
K
P
E
E
I
N
K
R
M
Q
E
L
T
R
E
M
--
D
---
E
A
DK
V
G
---
F
N
Y
F
I
V
N
D
D
L
A
R
T
Y
A
E
L
R
E
Y
L
L
G
S
Y
P
Q
L
R
G
G
45
HHSearch
79.40
36%
-102
- C5 -
1EX7
3
KGUA_YEAST
A:
[1-184]
-------
S
R
P
I
V
I
S
G
P
S
G
T
G
K
S
T
L
L
K
K
L
F
-
A
E
-
Y
P
--
D
S
F
G
F
--
S
V
S
S
T
T
R
T
P
R
A
G
E
V
N
G
K
D
Y
N
F
V
S
V
D
E
F
K
S
M
I
K
N
N
E
F
I
E
W
A
Q
F
S
G
N
--
Y
Y
--
G
S
T
V
A
S
V
K
Q
V
S
K
S
G
K
T
C
I
L
D
I
D
M
Q
G
V
K
S
V
K
A
I
P
E
L
-
N
---
A
R
F
L
F
I
A
P
P
S
V
E
D
L
K
K
R
L
E
G
R
G
T
E
T
E
E
S
I
N
K
R
L
S
A
A
Q
A
E
L
--
A
---
Y
A
E
T
G
A
---
H
D
K
V
I
V
N
D
D
L
D
K
A
Y
K
E
L
K
D
F
I
F
A
E
K
------
17
PsiBlast_PDB
79.10
37%
-101
- C5 -
1EX7
3
KGUA_YEAST
A:
[4-186]
----------
I
V
I
S
G
P
S
G
T
G
K
S
T
L
L
K
K
L
F
A
E
Y
-
P
D
--
S
-
F
G
F
--
S
V
S
S
T
T
R
T
P
R
A
G
E
V
N
G
K
D
Y
N
F
V
S
V
D
E
F
K
S
M
I
K
N
N
E
F
I
E
W
A
Q
F
S
G
N
--
Y
Y
--
G
S
T
V
A
S
V
K
Q
V
S
K
S
G
K
T
C
I
L
D
I
D
M
Q
G
V
K
S
V
K
A
I
P
E
L
-
N
---
A
R
F
L
F
I
A
P
P
S
V
E
D
L
K
K
R
L
E
G
R
G
T
E
T
E
E
S
I
N
K
R
L
S
A
A
Q
A
E
L
A
Y
A
---
E
T
--
G
A
---
H
D
K
V
I
V
N
D
D
L
D
K
A
Y
K
E
L
K
D
F
I
F
A
E
K
------