@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1267: (2015-12-22 )
MKSNKKSNHLRAIYRALVIAIGLAVIIVFNYFNRKNNNARSSRRACSCFFSLTGVNLEKIGSFDTGAKLIVLNHQSLLDIIYLEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDKKGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAEKFQLKIQPMVLINSIKIFNSKPLEAYKARTRLVMLESYTPDFSSPTWYEELQERMQKEYLKHYHELNA
Atome Classification :
(20 SA)
-------.........10......--..20.---.......30---........40....--..------..50......-..60...----------.....70..-.-.....80........-------90........100.......110......-.120------------.......130-------------.----.....-.-..140...-.---------...150....------...-160.----...--------------------..----.170..--.----------------....---180.-----...---------..----.190----.--.....----..200.....-----..210---------.--.......220.......230.....-------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------MKSNKKS
N
H
L
R
A
I
Y
R
A
L
--
V
I
A
I
G
---
L
A
V
I
I
V
F
N
Y
---FNRKNNNA
R
S
S
R
R
A
--
C
S
------
C
F
F
S
LTGV
N
L
-
E
KIGSFD----------TG
A
K
L
I
V
L
N-
H
-
Q
S
L
L
D
I
I
Y
L
E
A
YHPS-------
N
I
C
W
I
A
K
K
ELGEIPFYGHALTDT
G
M
I
L
I
D-REDK------------
K
G
I
V
S
L
L
K
---------------
A
----
C
K
E
K
L-D-QNR
P
L
V
I
F-P---------EGTRGKGGEK------FL
P
-
F
K
Q
G
----
A
K
I
--------------------
I
A
----
E
K
F
Q
L
K
--
I
----------------
Q
P
M
V
---
L
I
N
S
-----
I
K
I---------FN----SKP-----
L
--
E
A
Y
KA----R
T
R
L
V
M
L
ESY-----TPDF----------S--S
P
T
W
Y
E
E
L
Q
E
R
M
Q
K
E
Y
L
K
H
Y
H
ELNA-------
41
Fugue
85.95
17%
-84
- C3 -
2CVH
-
RADB_THEKO
A:
[1-220]
-----------
M
L
S
T
G
T
K
S
L
D
S
L
L
----
G
G
G
---
F
A
P
G
V
L
T
Q
V
---
Y
G
P
Y
A
----
S
G
K
T
T
--
L
A
------
L
Q
T
G
L
L
S
----------------------
G
K
K
V
A
Y
V
D
-
T
-
E
G
--------
G
F
S
P
E
-------
R
L
V
Q
M
A
E
T
R
-
G
L
N
P
E
E
A
L
S
R
----
F
I
L
F
T
-
P
S
D
F
------------
K
E
Q
R
R
V
I
G
---------------
S
----
L
K
K
T
V
-
D
-
S
N
F
A
L
V
V
V
-
D
---------
S
I
T
A
H
Y
R
A
E
E
NRSGL-
I
A
E
-
L
S
R
Q
----
L
Q
V
--------------------
L
L
----
W
I
A
R
K
H
--
N
----------------
I
P
V
I
---
V
I
N
Q
-----
V
H
F
---------
D
S
RTEM
T
K
P
-----
V
AE
Q
T
L
G
Y
----
R
C
K
D
I
L
R
L
D
K
-----
L
P
K
P
----------
G
--
L
R
V
A
V
L
E
R
H
-
R
F
R
P
E
G
L
M
A
Y
F
R
I
T
E
RGIEDVE
27
HHSearch
73.61
13%
-81
- C4 -
1IUQ
9
PLSB_CUCMO
A:
[96-347]
------------------------------------------------------
I
F
G
Q
N
Y
--
I
R
------
P
L
I
D
F
G
N
--
S
-
F
V
G
N
L
S
L
F
K
D
I
E
E
K
L
Q
Q
G
H
N
V
V
L
I
S
N
-
H
-
Q
T
E
A
D
P
A
I
I
S
L
L
L
E
K
TN
P
Y
I
A
E
N
T
I
F
V
A
G
D
R
V
L
A
D
P
L
C
K
P
F
S
I
G
R
N
L
I
C
V
Y
-
S
K
K
H
MFDIPEL
T
E
T
K
R
K
A
N
T
R
S
L
K
---------------
E
----
M
A
L
L
L
R
G
-
G
S
Q
L
I
W
I
A
-
P
---------
S
G
G
R
D
R
P
-
D
P
STGEWY
P
A
P
-
F
D
A
S
S
V
D
N
M
R
R
--------------------
L
I
----
Q
H
S
D
V
P
G
H
L
----------------
F
P
L
A
---
L
L
C
------
H
D
I
---------
M
P
----
P
P
------
R
--
V
I
A
F
N
----
G
A
G
L
S
V
A
P
E
I
-----
S
F
E
E
I
A
A
T
HKN
P
E
E
V
--
R
E
A
Y
S
K
A
L
F
D
S
V
A
M
Q
Y
N
V
L
K
T
A
I
S
G
-------
46
Fugue
73.32
16%
-38
- C3 -
4P0P
1
EME1_HUMAN
B:
[62-389]
------R
M
K
A
Q
R
P
E
E
C
L
K
H
I
I
V
V
L
D
P
V
L
L
Q
M
---
E
G
G
G
Q
L
L
G
A
---
L
Q
T
M
E
C
R
C
V
I
E
A
Q
A
VP
C
S
------
V
T
W
R
R
R
A
G
P
S
-
E
D
R
E
D
W
V
----------
E
E
P
T
V
L
V
L
L
R
A
-
E
A
F
V
S
M
I
D
N
G
K
T
L
Q
G
-------
F
V
T
D
I
T
A
K
T
A
G
K
--
A
L
S
L
V
I
V
D
Q
E
K
C
F
V
S
-
R
V
D
A
------------
E
E
A
L
V
D
L
Q
---------------
L
HTE
A
Q
A
Q
I
V
-
Q
-
S
W
K
E
L
A
D
F
T
C
---------
A
F
T
K
A
V
A
E
A
P
------
F
K
K
-
L
R
D
E
----
T
T
F
SFCLES
D
W
A
G
G
VKVDLAGRG
L
A
----
L
V
W
R
R
Q
--
I
----------------
Q
Q
L
N
RVS
L
E
M
A
-----
S
A
V
---------
V
N
----
A
Y
P
S
P
Q
L
L
V
--
Q
A
Y
Q
Q
CFS
D
K
E
R
Q
N
L
L
A
D
I
-----
Q
V
R
R
----------
T
--
S
R
R
I
G
P
E
L
S
R
R
I
Y
L
Q
M
T
T
L
Q
P
H
L
S
L
-------
42
Fugue
70.40
11%
-80
- C3 -
1DQW
-
PYRF_YEAST
A:
[1-267]
MHKAT
Y
K
E
R
A
A
T
H
P
S
P
V
A
A
K
L
F
N
I
--
M
H
E
K
Q
---
T
N
L
C
A
S
L
D
V
---
R
T
T
K
E
L
L
E
L
V
E
A
L
G
--
P
K
------
I
C
L
L
K
T
H
V
D
I
L
T
D
F
S
M
E
G
----------
T
V
K
P
L
K
A
L
S
-
A
-
K
Y
N
F
L
L
F
E
D
R
K
F
A
---------
D
I
G
N
T
V
K
L
Q
Y
S
A
G
V
Y
R
I
A
E
W
A
D
--
I
T
N
A
H
-
G
V
V
G
------------
P
G
I
V
S
G
L
K
---------------
Q
----
A
A
E
E
V
-
T
-
K
E
P
R
G
L
L
M
-
L
---------
A
E
L
S
C
K
G
S
L
S
------
T
G
E
-
Y
T
K
G
----
T
V
D
--------------------
I
A
----
K
S
D
K
D
F
--
V
IGFIAQRDMGGRDEGY
D
W
L
I
---
M
T
P
G
-----
V
G
L
DDKGDALGQ
Q
Y
----
R
T
V
-----
D
--
D
V
V
S
T
----
G
S
D
I
I
I
V
G
R
G
-----
L
F
A
K
----------
G
--
R
D
--
A
K
V
E
G
E
R
Y
R
K
A
G
W
E
A
Y
L
R
R
C
G
QQD----
37
Fugue
68.41
13%
-68
* C3 *
3WV7
1
?
A:
[10-210]
------------------
K
V
P
H
G
E
--
V
T
L
V
G
AG
R
L
G
F
R
T
A
L
N
L
---
M
Q
I
H
R
G
G
P
E
------------------
R
I
K
V
I
D
G
-
Q
K
V
S
A
D
D
----------
L
I
F
R
L
M
G
A
K
-
I
G
E
Y
K
V
K
F
I
E
S
L
A
C
D
G
F
-------
S
R
T
V
Q
G
I
P
E
Y
I
T
G
D
N
L
R
L
I
G
G
D
V
V
C
V
E
I
A
G
G
D
T
L
------------
P
I
T
T
E
I
I
R
---------------
Y
----
A
Q
E
------
R
G
A
A
T
I
S
-
T
---------
M
G
V
F
G
I
G
E
E
D
---------------------------------------------------
V
S
--
V
----------------
V
D
I
D
---
E
A
D
P
-----
E
N
P
---------
I
A
----
A
Y
L
-----
Q
--
A
E
G
I
H
----
E
H
V
L
V
G
T
G
K
L
-----
I
R
D
W
----------
E
PV
T
P
H
V
L
D
R
V
S
E
V
M
T
A
E
I
L
K
L
L
R
G
A
---------
38
Fugue
64.08
12%
-115
- C3 -
1BG6
-
?
?:
[4-187]
--------------
S
K
T
Y
A
V
L
G
L
G
--
N
G
G
H
A
---
F
A
A
Y
L
A
L
K
---------------------
G
------
Q
S
V
L
A
W
D
I
D
A
-
Q
R
I
K
E
I
Q
----------
D
R
G
A
I
I
A
E
G
-
P
-
G
L
A
G
T
A
H
P
D
L
L
T
S
D
-----------------------
I
G
L
A
V
K
D
A
D
V
I
L
I
V
-
V
P
-
A
------------
I
H
H
A
S
I
A
A
---------------
N
----
I
A
S
Y
I
-
S
-
E
G
Q
L
I
I
L
N
-
P
---------
G
A
T
G
-------------------
G
----
A
L
E
--------------------
F
R
----
K
I
L
R
E
N
--
G
----------------
A
P
E
V
---
T
I
G
E
-----
T
------------
S
----
S
M
L
-----
F
--
T
C
R
S
E
----
R
P
G
Q
V
T
V
N
A
I
-----
K
G
A
M
----------
D
--
F
A
C
L
P
A
A
K
A
G
W
A
L
E
Q
I
G
S
V
L
P
Q
Y
V
A
V
E-----
43
Fugue
62.57
11%
-54
- C3 -
2WTM
3
?
A:
[2-251]
-----G
A
M
Y
I
D
C
D
G
I
K
L
N
A
Y
L
D
M
P
--
K
N
N
P
E
---
K
C
P
L
C
I
I
I
H
G
FT
G
H
S
E
E
R
H
I
V
A
V
Q
E
T
--
L
N
E
I
G
V
A
T
L
R
A
D
M
Y
G
H
G
K
-
S
D
G
K
F
E
D
----------
H
T
L
F
K
W
L
T
N
-
I
-
L
A
V
V
D
Y
A
K
K
L
D
F
-------------------
V
T
D
I
Y
M
A
G
H
S
Q
G
G
L
S
V
M
L
A
A
-
A
M
E
R
------------
D
I
I
K
A
L
I
P
L
SPAAM
I
P
E
I
A
R
T
G
E
L
----
L
G
L
K
F
-
D
-
P
E
N
I
P
D
E
L
-
D
---------
A
W
D
G
R
K
L
K
G
N
------
Y
V
R
-
V
A
Q
T
----
I
R
V
--------------------
E
D
----
F
V
D
K
Y
T
-------------------
K
P
V
L
---
I
V
H
G
DQDEA
V
P
Y
---------
E
A
----
S
V
A
-----
F
--
S
K
Q
Y
K
----
N
C
K
L
V
T
I
P
G
D
-----
T
H
C
Y
----------
D
--
H
H
--
L
E
L
V
T
E
A
V
K
E
F
M
L
E
Q
I
A
K
----------
16
PsiBlast_PDB
62.05
22%
-48
* C5 *
1YPZ
1
TCC3_MOUSE
F:
[25-168]
--------------------------------------------------------------------------------------------------------------------
V
F
I
E
S
F
R
S
V
-------
T
I
H
W
Y
R
Q
K
P
N
Q
G
L
E
F
L
L
Y
V
L
A
T
P
T
H
I
F
L
D
-
K
E
Y
K
------------
K
-----
M
E
---------------
A
----
S
K
N
P
S
-
A
-
S
T
S
I
L
T
I
Y
-
S
LEEEDEAIY
Y
C
S
Y
G
E
G
S
S
G
------
F
H
K
V
F
A
E
G
----
T
K
L
--------------------
I
V
IPSD
K
R
L
D
A
D
--
I
SP--------------
K
P
T
I
---
F
L
P
S
-----
V
A
E
---------
T
N
----------------
L
H
K
T
----
G
T
Y
L
C
L
L
E
A
F
-----
F
P
D
V
----------
I
--
R
V
Y
W
K
E
K
D
G
N
T
I
L
D
S
Q
E
G
D
T
L
K
T
N
D
-------
32
HHSearch
39.88
20%
-7
- C4 -
2LND
-
?
A:
[39-64]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
R
---------------
D
----
I
I
K
S
M
-
K
D
N
G
K
P
L
V
V
F
-
V
---------
N
G
A
S
Q
N
D
V
N
E
------
F
Q
N
-
E
A
K
K
----
E
G
V
--------------------
S
Y
----
D
V
L
K
S
T
--
D
----------------
P
E
E
L
---
T
Q
R
V
-----
R
E
F
---------
L
K
----
T
A
G
-----
S
--
L
E
H
H
H
----
H
H
H
-------------------------------------------------------------
1
PsiBlast_PDB
37.63
38%
19
- C4 -
4DBL
-
BTUD_ECOLI
C:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
4
PsiBlast_PDB
37.28
38%
17
- C4 -
2QI9
1
BTUD_ECOLI
C:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
26
PsiBlast_CBE
36.71
38%
19
- C4 -
2QI9
1
BTUD_ECOLI
D:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
2
PsiBlast_PDB
36.57
38%
45
- C4 -
4FI3
1
BTUD_ECOLI
C:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
22
PsiBlast_CBE
36.50
38%
45
- C4 -
4FI3
1
BTUD_ECOLI
D:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
5
PsiBlast_PDB
36.21
38%
18
- C4 -
1L7V
-
BTUD_ECOLI
C:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
21
PsiBlast_CBE
35.19
38%
48
- C4 -
4R9U
2
BTUD_ECOLI
D:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------
13
PsiBlast_PDB
34.92
40%
-47
- C6 -
4OK6
-
?
A:
[148-188]
---------------------------------------------------------------------------------------------------
G
A
R
L
V
V
L
A
-
T
-
A
T
P
P
G
S
V
T
V
S
--
H
P
--------
N
I
E
E
V
A
L
S
T
T
G
E
I
P
F
Y
G
K
A
I
P
L
E
V
I
K
G
G
R
-
H
L
I
F
------------
C
H
S
K
K
K
C
D
---------------
E
----
L
A
A
K
L
-
I
-
N
A
V
A
Y
Y
R
G
-
L
---------
D
V
S
V
D
V
V
V
V
S
------
T
D
A
-
L
M
F
D
----
S
V
I
--------------------
D
C
----
N
T
C
V
T
Q
--
T
----------------
V
D
F
S
---
L
D
P
T
-----
F
T
I
---------
E
T
----
T
T
L
-----
P
--
Q
D
A
V
S
----
R
T
Q
R
R
G
R
T
G
R
-----
G
K
P
G
----------
I
--
Y
R
F
V
A
P
G
E
R
P
S
G
M
F
D
S
S
V
L
C
E
C
Y
D
A
-------
18
PsiBlast_PDB
34.72
40%
-41
- C6 -
3KQH
-
POLG_HCVCO
A:
[126-166]
---------------------------------------------------------------------------------------------------
G
A
R
L
V
V
L
A
-
T
-
A
T
P
P
G
S
V
T
V
P
--
H
P
--------
N
I
E
E
V
A
L
S
S
T
G
E
I
P
F
Y
G
K
A
I
P
I
E
T
I
K
G
G
R
-
H
L
I
F
------------
C
H
S
K
K
K
C
D
---------------
E
----
L
A
A
K
L
-
S
-
G
L
G
L
N
A
V
A
-
Y
---------
Y
R
G
L
D
V
S
V
I
P
------
T
S
G
-
D
V
I
V
----
V
A
T
--------------------
D
A
----
L
M
T
G
F
T
--
G
----------------
D
F
D
S
---
V
I
D
C
-----
N
T
C
---------
V
T
----
Q
T
V
-----
D
--
F
S
L
D
P
----
T
F
T
I
E
T
T
T
V
P
-----
Q
D
A
V
----------
S
--
R
S
Q
R
R
G
R
T
G
R
G
R
M
G
I
Y
R
F
V
T
P
G
E
R
P
-------
7
PsiBlast_PDB
34.70
34%
-27
* C2 *
3LIB
-
?
A:
[179-214]
-------------------------------------------------------------------------------
V
-
S
K
V
R
T
F
D
----------
T
G
Y
A
F
M
V
S
N
-
S
-
G
V
I
L
S
-------
H
P
T
-------
H
K
D
W
I
G
K
K
D
L
Y
D
F
G
G
E
E
L
E
K
A
S
R
D
I
K
N
G
I
-
G
G
H
L
------------
E
T
A
D
P
T
T
G
---------------
K
----
T
V
I
L
F
-
Y
-
E
P
V
E
T
G
D
F
-
A
---------
F
V
L
V
V
P
K
E
E
M
------
L
A
G
-
V
A
D
L
----
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
34.15
38%
50
- C4 -
4R9U
2
BTUD_ECOLI
C:
[58-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
----
G
Q
P
-----
L
--
E
A
W
S
A
-----
T
K
L
A
L
H
R
A
Y
LSQQQ
T
P
P
F
----------
A
--
T
P
V
W
H
Y
L
T
L
H
Q
H
D
K
T
R
T
E
L
L
N
D
V
A
G
-------