@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1070c: (2016-04-28 )
MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRAPQFTHR
Atome Classification :
(25 SA)
.........-10--.-........20........30---.........40........50.......-.60........70---........80........90...----.....100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......-220.....--..230.......240.......250.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
Y
E
T
I
L
V
E-R---D-Q
R
V
G
I
I
T
LNR
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
ATELDDDPDI
G
A
I
I
I
TGSA-KAFAAGA
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
LAAVR----T
P
T
I
A
A
V
A
G
YALGGG
C
E
L
A
M
M
C
D
V
L
IAADTAKFGQP
E
I
K
L
G
V
LPGMG
G
S
Q
R
L
T
R
A
IGKA
K
A
M
D
L
I
L
TGRTM
D
A
A
E
A
E
RSG
L
V
SRVV
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-SE
G
L
L
Y
E
R
--
R
L
F
H
S
AFATEDQSE
G
M
A
A
F
I
E
K
RAPQFTHR
26
PsiBlast_CBE
93.78
100%
-101
- C2 -
3Q0G
1
ECHA8_MYCTU
F:
[2-255]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
1
PsiBlast_PDB
93.55
100%
-99
- C2 -
3H81
5
ECHA8_MYCTU
A:
[23-278]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
R
22
PsiBlast_CBE
93.48
100%
-103
- C2 -
3H81
4
ECHA8_MYCTU
B:
[23-277]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
-
30
PsiBlast_CBE
92.76
100%
-105
- C2 -
3Q0G
2
ECHA8_MYCTU
B:
[2-254]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
---
118
HHSearch
92.67
100%
-99
- C2 -
3H81
5
ECHA8_MYCTU
A:
[24-278]
--
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
R
28
PsiBlast_CBE
92.65
100%
-102
- C2 -
3Q0G
2
ECHA8_MYCTU
D:
[2-255]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
-------
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
25
PsiBlast_CBE
92.51
100%
-101
- C2 -
3Q0J
1
ECHA8_MYCTU
C:
[2-256]
M
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
21
PsiBlast_CBE
92.51
100%
-99
- C2 -
3H81
6
ECHA8_MYCTU
C:
[23-278]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
R
23
PsiBlast_CBE
91.81
100%
-99
- C2 -
3Q0J
1
ECHA8_MYCTU
F:
[2-255]
M
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
---
32
PsiBlast_CBE
91.70
100%
-101
- C2 -
3PZK
2
ECHA8_MYCTU
B:
[2-254]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
---
29
PsiBlast_CBE
91.45
100%
-100
- C2 -
3Q0G
2
ECHA8_MYCTU
C:
[1-255]
M
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
27
PsiBlast_CBE
91.39
100%
-104
- C2 -
3Q0G
1
ECHA8_MYCTU
E:
[2-254]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
---
24
PsiBlast_CBE
91.31
100%
-99
- C2 -
3Q0J
1
ECHA8_MYCTU
D:
[3-257]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
-
5
PsiBlast_PDB
91.25
99%
-96
- C2 -
4FJW
-
ECHA8_MYCTU
D:
[1-256]
M
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
Q
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
-
2
PsiBlast_PDB
90.98
100%
-98
- C2 -
3Q0J
1
ECHA8_MYCTU
A:
[2-256]
M
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
31
PsiBlast_CBE
90.46
100%
-102
- C2 -
3PZK
1
ECHA8_MYCTU
C:
[3-254]
--
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
---
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
---
3
PsiBlast_PDB
89.78
100%
-99
- C2 -
3PZK
2
ECHA8_MYCTU
A:
[2-255]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
-------------
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
4
PsiBlast_PDB
89.50
100%
-98
- C2 -
3Q0G
2
ECHA8_MYCTU
A:
[2-256]
-
T
Y
E
T
I
L
V
E
-
R
---
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
----
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
------
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
----
T
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
-
S
E
G
L
L
Y
E
R
--
R
L
F
H
S
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
-
6
PsiBlast_PDB
81.13
61%
-94
- C2 -
3MOY
6
?
A:
[7-263]
-
T
Y
T
T
I
A
T
S
-
R
---
P
V
A
G
V
G
L
I
R
L
D
R
P
D
A
L
N
A
L
N
Q
----
T
L
E
A
E
V
L
D
A
A
R
D
F
D
A
D
L
E
I
G
A
I
V
V
T
G
S
E
-
R
A
F
A
A
G
A
D
I
A
E
M
V
---
T
L
T
P
H
Q
A
R
E
R
N
L
L
S
G
W
D
S
L
T
Q
V
R
----
K
P
I
V
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
L
C
D
L
V
I
A
A
D
T
A
R
F
G
Q
P
E
I
T
L
G
I
L
P
G
L
G
G
T
Q
R
L
T
R
A
V
G
K
A
K
A
M
D
L
C
L
T
G
R
S
L
T
A
E
E
A
E
R
V
G
L
V
S
R
I
V
P
A
A
D
L
L
D
E
A
L
A
V
A
Q
R
I
A
R
M
S
R
P
A
G
R
A
V
K
D
A
I
N
E
A
F
E
R
P
L
-
S
A
G
M
R
Y
E
R
--
D
A
F
Y
A
M
F
D
T
H
D
Q
T
E
G
M
T
A
F
L
E
K
R
T
P
E
F
T
D
R
38
PsiBlast_CBE
80.52
50%
-95
- C2 -
1DUB
2
ECHM_RAT
F:
[3-258]
-
N
F
Q
Y
I
I
T
E
-
K
KGK
N
-
S
S
V
G
L
I
Q
L
N
R
P
K
A
L
N
A
L
C
N
----
G
L
I
E
E
L
N
Q
A
L
E
T
F
E
E
D
P
A
V
G
A
I
V
L
T
G
G
E
-
K
A
F
A
A
G
A
D
I
K
E
M
Q
---
N
R
T
F
Q
D
C
Y
S
G
K
F
L
S
H
W
D
H
I
T
R
I
K
----
K
P
V
I
A
A
V
N
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
I
I
Y
A
G
E
K
A
Q
F
G
Q
P
E
I
L
L
G
T
I
P
G
A
G
G
T
Q
R
L
T
R
A
V
G
K
S
L
A
M
E
M
V
L
T
G
D
R
I
S
A
Q
D
A
K
Q
A
G
L
V
S
K
I
F
P
V
E
T
L
V
E
E
A
I
Q
C
A
E
K
I
A
N
N
S
K
I
I
V
A
M
A
K
E
S
V
N
A
A
F
E
M
T
L
-
T
E
G
N
K
L
E
K
--
K
L
F
Y
S
T
F
A
T
D
D
R
R
E
G
M
S
A
F
V
E
K
R
K
A
N
F
---
119
HHSearch
80.50
61%
-94
- C2 -
3MOY
6
?
A:
[8-263]
--
Y
T
T
I
A
T
S
R
P
---
V
-
A
G
V
G
L
I
R
L
D
R
P
D
A
L
N
A
L
N
Q
----
T
L
E
A
E
V
L
D
A
A
R
D
F
D
A
D
L
E
I
G
A
I
V
V
T
G
S
E
-
R
A
F
A
A
G
A
D
I
A
E
M
V
---
T
L
T
P
H
Q
A
R
E
R
N
L
L
S
G
W
D
S
L
T
Q
V
R
----
K
P
I
V
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
L
C
D
L
V
I
A
A
D
T
A
R
F
G
Q
P
E
I
T
L
G
I
L
P
G
L
G
G
T
Q
R
L
T
R
A
V
G
K
A
K
A
M
D
L
C
L
T
G
R
S
L
T
A
E
E
A
E
R
V
G
L
V
S
R
I
V
P
A
A
D
L
L
D
E
A
L
A
V
A
Q
R
I
A
R
M
S
R
P
A
G
R
A
V
K
D
A
I
N
E
A
F
E
R
P
L
-
S
A
G
M
R
Y
E
R
--
D
A
F
Y
A
M
F
D
T
H
D
Q
T
E
G
M
T
A
F
L
E
K
R
T
P
E
F
T
D
R
65
PsiBlast_CBE
70.14
46%
-90
- C2 -
4FZW
2
PAAF_ECOLI
B:
[7-258]
-----
L
I
V
S
-
R
---
Q
-
Q
R
V
L
L
L
T
L
N
R
P
A
A
R
N
A
L
N
N
A
L
L
M
Q
L
V
N
E
L
E
A
A
A
T
----
D
T
S
I
S
V
C
V
I
T
G
N
A
-
R
F
F
A
A
G
A
D
L
N
E
M
A
---
E
K
D
L
A
A
T
L
N
D
T
R
P
Q
L
W
A
R
L
Q
A
F
N
----
K
P
L
I
A
A
V
N
G
Y
A
L
G
A
G
C
E
L
A
L
L
C
D
V
V
V
A
G
E
N
A
R
F
G
L
P
E
I
T
L
G
I
M
P
G
A
G
G
T
Q
R
L
I
R
S
V
G
K
S
L
A
S
K
M
V
L
S
G
E
S
I
T
A
Q
Q
A
Q
Q
A
G
L
V
S
D
V
F
P
S
D
L
T
L
E
Y
A
L
Q
L
A
S
K
M
A
R
H
S
P
L
A
L
Q
A
A
K
Q
A
L
R
Q
S
Q
E
V
A
L
-
Q
A
G
L
A
Q
E
R
--
Q
L
F
T
L
L
A
A
T
E
D
R
H
E
G
I
S
A
F
L
Q
K
R
T
P
D
F
K
G
R
124
HHSearch
69.84
44%
-88
* C2 *
4FZW
1
PAAF_ECOLI
A:
[5-258]
---
S
E
L
I
V
S
-
R
---
Q
-
Q
R
V
L
L
L
T
L
N
R
P
A
A
R
N
A
L
N
N
----
A
L
L
M
Q
L
V
N
E
L
E
A
A
A
T
D
T
S
I
S
V
C
V
I
T
G
N
A
-
R
F
F
A
A
G
A
D
L
N
E
M
A
---
E
K
D
L
A
A
T
L
N
D
T
R
P
Q
L
W
A
R
L
Q
A
F
N
----
K
P
L
I
A
A
V
N
G
Y
A
L
G
A
G
C
E
L
A
L
L
C
D
V
V
V
A
G
E
N
A
R
F
G
L
P
E
I
T
L
G
I
M
P
G
A
G
G
T
Q
R
L
I
R
S
V
G
K
S
L
A
S
K
M
V
L
S
G
E
S
I
T
A
Q
Q
A
Q
Q
A
G
L
V
S
D
V
F
P
S
D
L
T
L
E
Y
A
L
Q
L
A
S
K
M
A
R
H
S
P
L
A
L
Q
A
A
K
Q
A
L
R
Q
S
Q
E
V
A
L
-
Q
A
G
L
A
Q
E
R
--
Q
L
F
T
L
L
A
A
T
E
D
R
H
E
G
I
S
A
F
L
Q
K
R
T
P
D
F
K
G
R
14
PsiBlast_PDB
69.27
46%
-90
- C2 -
4FZW
1
PAAF_ECOLI
A:
[7-258]
-----
L
I
V
S
-
R
---
Q
-
Q
R
V
L
L
L
T
L
N
R
P
A
A
R
N
A
L
N
N
A
L
L
M
Q
L
V
N
E
L
E
A
A
A
T
----
D
T
S
I
S
V
C
V
I
T
G
N
A
-
R
F
F
A
A
G
A
D
L
N
E
M
A
---
E
K
D
L
A
A
T
L
N
D
T
R
P
Q
L
W
A
R
L
Q
A
F
N
----
K
P
L
I
A
A
V
N
G
Y
A
L
G
A
G
C
E
L
A
L
L
C
D
V
V
V
A
G
E
N
A
R
F
G
L
P
E
I
T
L
G
I
M
P
G
A
G
G
T
Q
R
L
I
R
S
V
G
K
S
L
A
S
K
M
V
L
S
G
E
S
I
T
A
Q
Q
A
Q
Q
A
G
L
V
S
D
V
F
P
S
D
L
T
L
E
Y
A
L
Q
L
A
S
K
M
A
R
H
S
P
L
A
L
Q
A
A
K
Q
A
L
R
Q
S
Q
E
V
A
L
-
Q
A
G
L
A
Q
E
R
--
Q
L
F
T
L
L
A
A
T
E
D
R
H
E
G
I
S
A
F
L
Q
K
R
T
P
D
F
K
G
R
69
PsiBlast_CBE
62.98
37%
-81
- C2 -
3R0O
4
?
B:
[13-273]
-
T
R
Q
A
A
V
V
E
-
R
---
R
-
G
N
V
A
L
I
T
I
D
R
P
D
A
R
N
A
V
N
G
----
A
V
S
T
A
V
G
D
A
L
E
E
A
Q
R
D
P
E
V
W
A
V
V
I
T
G
A
G
D
K
S
F
C
A
G
A
D
L
K
A
I
S
R
GE
N
L
Y
H
A
E
------
H
P
E
W
G
F
A
G
Y
V
H
HFID
K
P
T
I
A
A
V
N
G
T
A
L
G
G
G
S
E
L
A
L
A
S
D
L
V
I
A
C
E
S
A
S
F
G
L
P
E
V
K
R
G
L
I
A
G
A
G
G
V
F
R
I
V
E
Q
L
P
R
K
V
A
L
E
L
V
L
T
G
E
P
M
T
A
S
D
A
L
R
W
G
L
I
N
E
V
V
P
D
G
T
V
V
E
A
A
L
A
L
A
E
R
I
T
C
N
A
P
L
S
V
Q
A
S
K
R
V
A
Y
G
A
D
D
G
I
I
G
A
E
E
P
K
W
E
R
T
I
R
E
F
T
E
L
L
K
S
E
D
A
K
E
G
P
L
A
F
A
E
K
R
Q
P
V
W
K
A
R