@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4748: (2016-03-01 )
MRRPLVAGNWKMHGTHSSVAELIKGLRQLALPSGVDVAVMPPCLFISQVIQGLAGKAIDVGAQNSAVEPMQGALTGETAPSQLADVGCSMVLVGHSERRLILGESDEVVSRKFAAAQSCGLVPVLCVGETRAEREAGKTLEVVARQLGSVIDELGVGAFARAVVAYEPVWAIGTGLTASPAQAQEVHAAIRAQLAAENAEVAKGVRLLYGGSVKAASAAELFGMPDIDGGLVGGASLNADEFGAICRAAGS
Atome Classification :
(67 SA)
-.........10........20......-.--.30-.-.......40........50..-.--...--..60........70........80........90........100.......110.........120.......130.......140.......150.......160.......170.......180.......190....-.-.--.200........210.......220.......230.......240.......250---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MRRPLVAGN
W
K
MHG
T
H
S
S
V
A
E
L
I
K
G
L
R
-
Q
--LAL-P-SGV
D
V
AVM
P
P
C
L
F
I
S
Q
V
I
Q
G
L-A--GK
A
--
I
DVGAQNSAVEP
M
Q
GALTGETA
P
S
Q
L
A
D
VGC
S
M
V
L
VGHSE
R
R
L
I
LGES
D
E
V
V
S
--
R
K
F
A
A
A
QSCG
L
V
P
V
L
CVGE
T
R
A
E
R
EAG
K
T
L
E
V
V
A
R
Q
L
G
S
V
I
D
E
L
G
V
G
A
F
A
R
A
V
V
AYEP
V
W
AIGTGLTASP
A
Q
A
Q
E
V
H
A
A
I
R
A
Q
L
AA-E-
N
--
A
E
-
V
A
K
G
V
R
L
L
YGGSVKAA
S
A
A
E
LFGMPDIDGGLVGGASL
N
A
D
E
F
G
A
I
C
RAAGS----
21
PsiBlast_CBE
94.39
52%
-113
- C5 -
4MVA
3
?
B:
[25-273]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
------
1
PsiBlast_PDB
93.96
52%
-110
- C5 -
4K6A
1
?
A:
[25-273]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
------
4
PsiBlast_PDB
93.38
52%
-108
- C5 -
4IOT
1
TPIS_ECODH
A:
[1-249]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
------
2
PsiBlast_PDB
93.24
52%
-109
- C5 -
4MVA
4
?
A:
[25-273]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
------
8
PsiBlast_PDB
90.92
49%
-101
- C5 -
4OHQ
-
TPIC_ARATH
A:
[6-251]
---
K
F
F
V
G
G
N
W
K
C
N
G
T
K
D
S
I
A
K
L
I
S
D
L
N
-
S
--
A
T
L
-
E
-
A
D
V
D
V
V
V
S
P
P
F
V
Y
I
D
Q
V
K
S
S
L
-
T
--
D
R
---
I
D
I
S
G
Q
N
S
W
V
-
G
K
G
G
A
F
T
G
E
I
S
V
E
Q
L
K
D
L
G
C
K
W
V
I
L
G
H
S
E
R
R
H
V
I
G
E
K
D
E
F
I
G
--
K
K
A
A
Y
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
E
E
R
E
A
G
K
T
F
D
V
C
F
A
Q
L
K
A
F
A
D
--
A
V
P
S
W
D
N
I
V
V
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
S
P
Q
Q
A
Q
E
V
H
V
A
V
R
G
W
L
K
K
-
N
V
S
--
E
E
-
V
A
S
K
T
R
I
I
Y
G
G
S
V
N
G
G
N
S
A
E
L
A
K
E
E
D
I
D
G
F
L
V
G
G
A
S
L
K
G
P
E
F
A
T
I
V
N
S
V
T
S
----
3
PsiBlast_PDB
90.49
52%
-105
- C5 -
1TRE
-
TPIS_ECOLI
A:
[3-251]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
N
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
------
101
Fugue
89.96
52%
-102
- C5 -
1TRE
-
TPIS_ECOLI
A:
[3-257]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
-
K
--
E
L
A
-
G
V
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
E---
G
S
H
--
I
M
L
G
A
Q
N
V
N
L
N
L
-
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
K
QA
24
PsiBlast_CBE
88.81
51%
-105
- C5 -
1TMH
1
TPIS_ECOLI
B:
[1-248]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
A
------
17
PsiBlast_PDB
88.70
45%
-107
- C5 -
1R2T
-
TPIS_RABIT
A:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
22
PsiBlast_CBE
88.65
51%
-103
- C5 -
1TMH
1
TPIS_ECOLI
D:
[1-248]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
A
------
23
PsiBlast_CBE
88.62
51%
-105
- C5 -
1TMH
1
TPIS_ECOLI
C:
[1-248]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
A
------
44
PsiBlast_CBE
88.48
45%
-109
- C5 -
1R2R
7
TPIS_RABIT
D:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
14
PsiBlast_PDB
88.38
44%
-104
- C5 -
4Y8F
5
?
A:
[4-248]
-
M
R
T
P
I
I
A
G
N
W
K
M
H
Y
T
I
D
E
A
V
K
L
V
E
E
L
K
-
P
--
L
V
K
-
D
-
A
K
C
E
V
V
V
C
P
T
F
V
C
L
D
A
V
K
K
A
V
-
E
--
G
T
N
--
I
K
V
G
A
Q
N
M
H
F
E
E
-
K
G
A
F
T
G
E
I
A
P
R
M
L
E
A
M
N
I
D
Y
V
I
I
G
H
S
E
R
R
E
Y
F
N
E
T
D
E
T
C
N
--
K
K
V
K
A
A
F
A
H
N
L
T
P
I
L
C
C
G
E
T
L
E
Q
R
E
N
G
T
T
N
D
V
I
K
A
Q
I
T
A
D
L
E
G
L
T
K
E
Q
A
E
K
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
T
A
T
S
D
Q
A
N
E
T
I
A
A
I
R
A
M
V
A
E
-
M
F
G
--
Q
E
-
V
A
D
K
V
R
I
Q
Y
G
G
S
V
K
P
N
T
I
A
E
Q
M
A
K
S
D
I
D
G
A
L
V
G
G
A
S
L
V
A
A
D
F
A
Q
I
----------
113
HHSearch
88.33
50%
-102
- C5 -
1AW2
1
TPIS_MORMI
A:
[2-252]
--
R
H
P
V
V
M
G
N
W
K
L
N
G
S
K
E
M
V
V
D
L
L
N
G
L
N
-
A
--
E
L
E
G
V
-
T
G
V
D
V
A
V
A
P
P
A
L
F
V
D
L
A
E
R
T
L
-
T
E
A
G
S
A
--
I
I
L
G
A
Q
N
T
D
-
L
N
N
S
G
A
F
T
G
D
M
S
P
A
M
L
K
E
F
G
A
T
H
I
I
I
G
H
S
E
R
R
E
Y
H
A
E
S
D
E
F
V
A
--
K
K
F
A
F
L
K
E
N
G
L
T
P
V
L
C
I
G
E
S
D
A
Q
N
E
A
G
E
T
M
A
V
C
A
R
Q
L
D
A
V
I
N
T
Q
G
V
E
A
L
E
G
A
I
I
A
Y
E
P
I
W
A
I
G
T
G
K
A
A
T
A
E
D
A
Q
R
I
H
A
Q
I
R
A
H
I
A
E
-
K
-
S
--
E
A
-
V
A
K
N
V
V
I
Q
Y
G
G
S
V
K
P
E
N
A
A
A
Y
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
A
L
D
A
K
S
F
A
A
I
A
K
A
A
A
-----
37
PsiBlast_CBE
88.33
50%
-101
- C5 -
4G1K
5
?
B:
[26-271]
--
R
I
K
R
V
I
G
N
W
K
M
H
G
R
L
S
G
N
Q
A
L
L
T
E
V
A
-
Q
G
A
Q
A
V
-
H
-
D
N
V
A
I
G
V
C
V
P
F
P
Y
L
A
Q
A
Q
A
Q
L
-
Q
--
G
G
R
--
V
S
W
G
S
Q
D
V
S
A
H
E
-
Q
G
A
Y
T
G
E
V
A
A
G
M
V
A
E
F
G
A
A
Y
A
I
V
G
H
S
E
R
R
A
Y
H
G
E
S
N
E
T
V
A
--
A
K
A
R
R
A
L
A
A
G
L
T
P
I
V
C
V
G
E
T
L
A
E
R
E
A
G
T
T
E
Q
V
V
G
A
Q
L
D
A
V
L
A
V
L
S
P
D
E
A
A
R
I
V
V
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
A
E
Q
A
Q
Q
V
H
A
F
L
R
G
R
L
A
A
-
K
-
G
------
A
G
H
V
S
L
L
Y
G
G
S
V
K
A
D
N
A
A
E
L
F
G
Q
P
D
I
D
G
G
L
I
G
G
A
S
L
K
S
G
D
F
L
A
I
C
R
A
A
------
35
PsiBlast_CBE
88.11
50%
-105
- C5 -
4G1K
4
?
D:
[26-271]
--
R
I
K
R
V
I
G
N
W
K
M
H
G
R
L
S
G
N
Q
A
L
L
T
E
V
A
-
Q
GA
Q
A
V
-
H
-
D
N
V
A
I
G
V
C
V
P
F
P
Y
L
A
Q
A
Q
A
Q
L
-
Q
--
G
G
R
--
V
S
W
G
S
Q
D
V
S
A
H
E
-
Q
G
A
Y
T
G
E
V
A
A
G
M
V
A
E
F
G
A
A
Y
A
I
V
G
H
S
E
R
R
A
Y
H
G
E
S
N
E
T
V
A
--
A
K
A
R
R
A
L
A
A
G
L
T
P
I
V
C
V
G
E
T
L
A
E
R
E
A
G
T
T
E
Q
V
V
G
A
Q
L
D
A
V
L
A
V
L
S
P
D
E
A
A
R
I
V
V
A
Y
E
P
V
W
A
------
A
T
A
E
Q
A
Q
Q
V
H
A
F
L
R
G
R
L
A
A
-
K
-
G
------
A
G
H
V
S
L
L
Y
G
G
S
V
K
A
D
N
A
A
E
L
F
G
Q
P
D
I
D
G
G
L
I
G
G
A
S
L
K
S
G
D
F
L
A
I
C
R
A
A
------
36
PsiBlast_CBE
87.92
50%
-101
- C5 -
4G1K
5
?
C:
[26-271]
--
R
I
K
R
V
I
G
N
W
K
M
H
G
R
L
S
G
N
Q
A
L
L
T
E
V
A
-
Q
GA
Q
A
V
-
H
-
D
N
V
A
I
G
V
C
V
P
F
P
Y
L
A
Q
A
Q
A
Q
L
-
Q
--
G
G
R
--
V
S
W
G
S
Q
D
V
S
A
H
E
-
Q
G
A
Y
T
G
E
V
A
A
G
M
V
A
E
F
G
A
A
Y
A
I
V
G
H
S
E
R
R
A
Y
H
G
E
S
N
E
T
V
A
--
A
K
A
R
R
A
L
A
A
G
L
T
P
I
V
C
V
G
E
T
L
A
E
R
E
A
G
T
T
E
Q
V
V
G
A
Q
L
D
A
V
L
A
V
L
S
P
D
E
A
A
R
I
V
V
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
A
E
Q
A
Q
Q
V
H
A
F
L
R
G
R
L
A
A
-
K
-
G
------
A
G
H
V
S
L
L
Y
G
G
S
V
K
A
D
N
A
A
E
L
F
G
Q
P
D
I
D
G
G
L
I
G
G
A
S
L
K
S
G
D
F
L
A
I
C
R
A
A
------
5
PsiBlast_PDB
87.90
51%
-106
- C5 -
1TMH
1
TPIS_ECOLI
A:
[1-248]
-
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
K
E
--
L
A
G
-
V
-
A
G
C
A
V
A
I
A
P
P
E
M
Y
I
D
M
A
K
R
E
A
-
E
--
G
S
H
--
I
M
L
G
A
Q
N
V
D
L
N
-
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
--
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
D
H
I
A
K
-
V
-
D
--
A
N
-
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
A
------
45
PsiBlast_CBE
87.68
45%
-106
- C5 -
1R2R
9
TPIS_RABIT
C:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
9
PsiBlast_PDB
87.57
50%
-102
- C5 -
4G1K
4
?
A:
[26-271]
--
R
I
K
R
V
I
G
N
W
K
M
H
G
R
L
S
G
N
Q
A
L
L
T
E
V
A
-
Q
G
A
Q
A
V
-
H
-
D
N
V
A
I
G
V
C
V
P
F
P
Y
L
A
Q
A
Q
A
Q
L
-
Q
--
G
G
R
--
V
S
W
G
S
Q
D
V
S
A
H
E
-
Q
G
A
Y
T
G
E
V
A
A
G
M
V
A
E
F
G
A
A
Y
A
I
V
G
H
S
E
R
R
A
Y
H
G
E
S
N
E
T
V
A
--
A
K
A
R
R
A
L
A
A
G
L
T
P
I
V
C
V
G
E
T
L
A
E
R
E
A
G
T
T
E
Q
V
V
G
A
Q
L
D
A
V
L
A
V
L
S
P
D
E
A
A
R
I
V
V
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
A
E
Q
A
Q
Q
V
H
A
F
L
R
G
R
L
A
A
-
K
-
G
------
A
G
H
V
S
L
L
Y
G
G
S
V
K
A
D
N
A
A
E
L
F
G
Q
P
D
I
D
G
G
L
I
G
G
A
S
L
K
S
G
D
F
L
A
I
C
R
A
A
------
84
PsiBlast_CBE
87.07
42%
-108
- C5 -
2Y62
3
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
68
PsiBlast_CBE
86.69
44%
-106
- C5 -
4HHP
2
?
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
-
A
--
A
T
F
-
D
-
H
D
V
Q
C
V
V
A
P
T
F
L
H
I
P
M
T
K
A
R
L
-
T
--
N
P
K
--
F
Q
I
A
A
Q
N
A
I
T
R
--
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
D
T
N
E
I
V
A
--
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
S
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
R
W
V
R
S
-
K
L
G
--
T
D
-
I
A
A
Q
L
R
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
-------
10
PsiBlast_PDB
86.53
45%
-101
- C5 -
4MKN
6
?
A:
[20-265]
---
K
F
F
V
G
G
N
W
K
C
N
G
S
V
A
N
V
A
K
L
V
D
E
L
N
-
A
--
G
T
I
-
P
-
R
G
V
D
V
V
V
A
P
P
F
I
Y
I
D
Y
V
M
Q
H
L
-
D
--
R
D
K
--
Y
Q
L
S
A
Q
N
A
W
I
G
G
-
N
G
A
F
T
G
E
V
S
A
E
Q
L
T
D
F
G
V
P
W
V
I
L
G
H
S
E
R
R
S
L
F
G
E
S
N
E
V
V
A
--
K
K
T
S
H
A
L
A
A
G
L
G
V
I
A
C
I
G
E
T
L
E
Q
R
N
S
G
S
V
F
K
V
L
D
A
Q
M
D
A
L
V
D
E
--
V
K
D
W
T
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
V
V
A
S
P
E
Q
A
Q
E
V
H
A
Y
L
R
Q
Y
C
A
K
-
K
L
G
--
A
A
-
V
A
D
K
L
R
I
I
Y
G
G
S
V
S
D
T
N
C
K
D
L
S
K
Q
E
D
I
D
G
F
L
V
G
G
A
S
L
K
G
A
A
F
V
T
I
C
N
A
A
G
-----
83
PsiBlast_CBE
86.46
42%
-106
- C5 -
2Y63
1
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
102
Fugue
86.30
41%
-103
- C5 -
1IF2
1
TPIS_LEIME
A:
[3-251]
A
K
P
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
--
A
I
A
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
K
W
V
S
E
-
N
I
G
--
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
E
-
F
R
D
I
I
D
A
T
R
-----
88
PsiBlast_CBE
86.22
42%
-107
- C5 -
1N55
6
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
85
PsiBlast_CBE
85.90
42%
-106
- C5 -
2Y61
3
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
18
PsiBlast_PDB
85.54
45%
-103
- C5 -
4OWG
1
TPIS_RABIT
A:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
86
PsiBlast_CBE
85.47
42%
-105
- C5 -
2VXN
7
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
80
PsiBlast_CBE
85.41
43%
-104
- C5 -
1SW7
1
TPIS_CHICK
A:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
N
S
S
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
87
PsiBlast_CBE
85.37
42%
-104
- C5 -
1QDS
1
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
116
HHSearch
85.30
39%
-106
- C5 -
2J27
1
TPIS_TRYBB
A:
[3-249]
-
K
P
Q
P
I
A
A
A
N
W
K
C
N
G
S
Q
Q
S
L
S
E
L
I
D
L
F
N
-
S
--
T
S
I
-
N
-
H
D
V
Q
C
V
V
A
S
T
F
V
H
L
A
M
T
K
E
R
L
-
S
--
H
P
K
--
F
V
I
A
A
Q
N
A
I
-
A
-
K
S
G
A
F
T
G
E
V
S
L
P
I
L
K
D
F
G
V
N
W
I
V
L
G
H
S
E
R
R
A
Y
Y
G
E
T
N
E
I
V
A
--
D
K
V
A
A
A
V
A
S
G
F
M
V
I
A
C
I
G
E
T
L
Q
E
R
E
S
G
R
T
A
V
V
V
L
T
Q
I
A
A
I
A
K
K
L
K
K
A
D
W
A
K
V
V
I
A
Y
E
A
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
A
H
A
L
I
R
S
W
V
S
S
-
K
-
I
--
G
A
D
V
A
G
E
L
R
I
L
Y
G
G
S
V
N
G
K
N
A
R
T
L
Y
Q
Q
R
D
V
N
G
F
L
V
G
G
A
S
L
K
P
E
-
F
V
D
I
I
K
A
T
------
120
HHSearch
85.08
42%
-102
- C5 -
2VXN
7
TPIS_LEIME
A:
[4-250]
-
K
P
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
-
A
-
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
K
W
V
S
E
-
N
-
I
--
G
T
D
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
E
-
F
R
D
I
I
D
A
T
------
95
PsiBlast_CBE
84.61
40%
-104
- C5 -
3UWW
3
TPIS_STAAR
A:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
79
PsiBlast_CBE
84.57
43%
-101
- C5 -
1SW7
1
TPIS_CHICK
B:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
N
S
S
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
64
PsiBlast_CBE
84.42
44%
-102
- C5 -
1SW0
1
TPIS_CHICK
A:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
L
W
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
89
PsiBlast_CBE
84.40
42%
-102
- C5 -
1IF2
1
TPIS_LEIME
A:
[6-249]
---
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
-
E
--
H
T
I
-
S
-
H
D
V
Q
C
V
V
A
P
T
F
V
H
I
P
L
V
Q
A
K
L
-
R
--
N
P
K
--
Y
V
I
S
A
Q
N
A
I
A
K
--
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
--
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
-
K
W
V
S
-
E
-
N
IG
T
D
-
V
A
A
K
L
R
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
-------
72
PsiBlast_CBE
84.32
44%
-103
- C5 -
1SW3
1
TPIS_CHICK
A:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
99
PsiBlast_CBE
84.25
40%
-102
- C5 -
3UWU
2
TPIS_STAAR
A:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
74
PsiBlast_CBE
84.08
44%
-104
- C5 -
1TPW
1
TPIS_CHICK
A:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
P
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
T
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
97
PsiBlast_CBE
84.01
40%
-101
- C5 -
3UWV
5
TPIS_STAAR
A:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
94
PsiBlast_CBE
83.88
40%
-101
- C5 -
3UWW
3
TPIS_STAAR
B:
[10-253]
--
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
121
HHSearch
83.76
39%
-104
- C5 -
1O5X
2
TPIS_PLAFA
A:
[3-247]
--
R
K
Y
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
-
N
--
L
D
F
D
P
-
S
K
L
D
V
V
V
F
P
V
S
V
H
Y
D
H
T
R
K
L
L
----
Q
S
K
--
F
S
T
G
I
Q
N
V
S
-
K
F
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
--
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
D
--
N
F
D
N
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
-
T
-
C
--
G
E
K
Q
A
N
Q
I
R
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
K
E
-
S
F
V
D
I
I
K
S
A
------
43
PsiBlast_CBE
83.65
45%
-102
- C5 -
4OWG
1
TPIS_RABIT
B:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
71
PsiBlast_CBE
83.60
44%
-103
- C5 -
1SW3
1
TPIS_CHICK
B:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
76
PsiBlast_CBE
83.54
43%
-102
- C5 -
1SSG
4
TPIS_CHICK
A:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
Y
S
L
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
98
PsiBlast_CBE
83.43
40%
-101
- C5 -
3UWU
1
TPIS_STAAR
B:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
63
PsiBlast_CBE
83.35
44%
-101
- C5 -
1SW0
1
TPIS_CHICK
B:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
L
W
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
49
PsiBlast_CBE
83.05
45%
-102
- C5 -
1HTI
1
TPIS_HUMAN
B:
[4-246]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
R
K
Q
S
L
G
E
L
I
G
T
L
N
-
A
--
A
K
V
-
P
-
A
D
T
E
V
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
L
-
D
--
P
K
---
I
A
V
A
A
Q
N
-
C
Y
K
V
T
N
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
--
N
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
N
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
93
PsiBlast_CBE
82.99
40%
-101
- C5 -
3UWZ
1
TPIS_STAAR
A:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
111
HHSearch
82.97
40%
-101
- C5 -
2BTM
1
TPIS_GEOSE
A:
[1-250]
--
R
K
P
I
I
A
G
N
W
K
M
N
G
T
L
A
E
A
V
Q
F
V
E
D
V
K
-
G
--
H
V
P
P
A
-
D
E
V
I
S
V
V
C
A
P
F
L
F
L
D
R
L
V
Q
A
A
-
D
--
G
T
D
--
L
K
I
G
A
Q
T
M
H
-
F
A
D
Q
G
A
Y
T
G
E
V
S
P
V
M
L
K
D
L
G
V
T
Y
V
I
L
G
H
S
E
R
R
Q
M
F
A
E
T
D
E
T
V
N
--
K
K
V
L
A
A
F
T
R
G
L
I
P
I
I
C
C
G
E
S
L
E
E
R
E
A
G
Q
T
N
A
V
V
A
S
Q
V
E
K
A
L
A
G
L
T
P
E
Q
V
K
Q
A
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
P
E
D
A
N
S
V
C
G
H
I
R
S
V
V
S
R
-
L
-
F
--
G
P
E
A
A
E
A
I
R
I
Q
Y
G
G
S
V
K
P
D
N
I
R
D
F
L
A
Q
Q
Q
I
D
G
A
L
V
G
G
A
S
L
E
P
A
S
F
L
Q
L
V
E
A
G
R
-----
96
PsiBlast_CBE
82.75
40%
-101
- C5 -
3UWV
4
TPIS_STAAR
B:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
90
PsiBlast_CBE
82.60
40%
-101
- C5 -
3M9Y
3
TPIS_STAAR
B:
[2-246]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
81
PsiBlast_CBE
82.24
44%
-98
- C5 -
1TPU
1
TPIS_CHICK
B:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
N
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
T
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
92
PsiBlast_CBE
82.16
40%
-104
- C5 -
3UWZ
2
TPIS_STAAR
B:
[9-253]
-
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
-
T
--
L
P
D
-
S
-
K
E
V
E
S
V
I
C
A
P
A
I
Q
L
D
A
L
T
T
A
V
-
K
E
-
G
K
A
QG
L
E
I
G
A
Q
N
T
Y
F
E
D
-
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
--
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
V
V
I
A
Y
E
P
I
W
A
I
---
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
Q
T
I
A
D
L
S
-
S
--
K
E
-
V
S
E
A
T
R
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
-------------
73
PsiBlast_CBE
82.07
44%
-100
- C5 -
1TPW
1
TPIS_CHICK
B:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
P
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
T
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
75
PsiBlast_CBE
81.82
43%
-100
- C5 -
1SSG
6
TPIS_CHICK
B:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
Y
S
L
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
S
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
82
PsiBlast_CBE
81.48
44%
-99
- C5 -
1TPU
1
TPIS_CHICK
A:
[3-245]
--
R
K
F
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
H
T
L
N
-
G
--
A
K
L
-
S
-
A
D
T
E
V
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
L
-
D
--
A
K
---
I
G
V
A
A
Q
N
C
Y
K
V
P
-
K
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
N
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
--
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
--
V
K
D
W
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
G
W
L
K
T
-
H
-
V
--
S
D
A
V
A
Q
S
T
R
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
P
-
E
F
V
D
I
I
N
A
-------
60
PsiBlast_CBE
81.03
42%
-108
- C5 -
3YPI
1
TPIS_YEAST
A:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
Q
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
D
K
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
54
PsiBlast_CBE
80.15
43%
-108
- C5 -
2YPI
1
TPIS_YEAST
A:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
D
K
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
61
PsiBlast_CBE
79.68
42%
-108
- C5 -
4FF7
13
TPIS_YEAST
B:
[3-236]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
DK
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
S
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
62
PsiBlast_CBE
78.40
42%
-104
- C5 -
4FF7
9
TPIS_YEAST
A:
[3-236]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
D
K
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
S
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
125
HHSearch
78.04
40%
-95
- C5 -
3KXQ
4
TPIS_BARHE
A:
[26-273]
--
I
R
P
F
I
A
G
N
W
K
M
N
G
T
G
E
S
L
G
E
L
R
A
I
A
A
-
G
--
I
S
----
R
L
F
E
A
L
I
C
V
P
A
T
L
L
S
R
A
F
D
I
L
-
G
--
G
E
N
--
I
L
L
G
G
Q
N
C
H
-
F
D
D
Y
G
P
Y
T
G
D
I
S
A
F
M
L
K
E
A
G
A
S
H
V
I
I
G
H
S
E
R
R
T
V
Y
Q
E
S
D
A
I
V
R
--
A
K
V
Q
A
A
W
R
A
G
L
V
A
L
I
C
V
G
E
T
L
E
E
R
K
S
N
K
V
L
D
V
L
T
R
Q
L
E
G
S
L
P
D
G
A
--
T
A
E
N
I
I
I
A
Y
E
P
V
W
--------
T
S
A
D
V
A
E
V
H
A
F
I
H
H
K
M
H
S
-
R
-
F
--
G
D
-
E
G
A
K
I
R
L
L
Y
G
G
S
V
K
P
S
N
A
F
E
L
L
S
T
A
H
V
N
G
A
L
I
G
G
A
S
L
K
A
I
D
F
L
T
I
C
D
V
Y
R
-----
52
PsiBlast_CBE
77.22
43%
-102
- C5 -
7TIM
1
TPIS_YEAST
A:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
D
K
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
59
PsiBlast_CBE
77.00
42%
-105
- C5 -
3YPI
1
TPIS_YEAST
B:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
Q
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
DK
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
51
PsiBlast_CBE
76.14
43%
-101
- C5 -
7TIM
1
TPIS_YEAST
B:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
DK
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------
53
PsiBlast_CBE
70.90
43%
-94
- C5 -
2YPI
1
TPIS_YEAST
B:
[2-235]
--
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
-
T
--
A
S
I
-
P
-
E
N
V
E
V
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
V
-
K
--
K
P
Q
--
V
T
V
G
A
Q
N
A
Y
L
K
A
-
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
H
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
DK
T
K
F
A
L
G
Q
G
V
G
V
I
--
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
--
V
K
D
W
T
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
K
F
L
A
S
-
K
L
G
--
D
K
-
A
A
S
E
L
R
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
------------------