@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0141c: (2016-04-19 )
MTPFDDPQAELAWMFLQSLCEGGDLDEGFALLSNDFTYWSIVTRTELDKKTFRRAVERRKQVFEVNIELIRCVNEGETVVVEGHCDGVSADRTRYDSPFVCIFETRDGMIISLREYSDTQSLAEVYPVACATPGRC
Atome Classification :
(20 SA)
------------------.........-10.....-.-.-.20...--.....30......-..40-.-.-------.-...-..50.........-60...--..-....-70..--......80......--------.-.---------90--------..--.......100....-...110.......120.......130.-...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------MTPFD
D
P
Q
A
-
E
L
A
W
M
F
L
-
Q
-
S
-LCEGGD--L
D
E
G
F
A
L
LSNDF
T
-
Y
W
S
I
-
V
-
T
-------R-TEL-
D
K
K
-
T
F
R
R
A
V
E
R
R
-
K
-
Q
V
F
--
E
V
-
N
I
E
L
-
I
R
C
V--NEG
E
T
V
V
V
EGHCDG--------V-S---------A---------DR--TRYDS
P
F
V
C
I
F
ETR-D
G
M
I
I
S
L
REYS
D
T
Q
S
L
A
E
VY
P
V
ACATP-GRC
29
HHSearch
91.17
19%
-101
- C3 -
3F7X
8
?
A:
[19-151]
----------------------
G
M
T
A
T
-
E
L
V
N
A
Y
Y
-
A
-
A
-
F
N
A
-
G
D
--
M
P
A
F
L
A
L
L
S
E
D
V
I
-
H
D
I
N
-
Q
-
G
-------
E
-
R
Q
M
-
G
K
A
-
R
F
A
A
F
M
E
K
M
-
N
-
R
C
Y
R
-
E
R
-
L
A
D
I
V
V
M
Q
N
--
A
D
G
S
R
A
A
A
E
F
T
V
H
G
--------
Q
-
Y
L
A
DDEGLPT
A
---------
N
G
--
Q
T
Y
V
L
P
A
G
A
F
F
Y
I
H
-
C
G
K
I
A
R
V
T
N
Y
Y
N
L
N
D
W
V
E
Q
V
A
----------
26
HHSearch
86.35
20%
-101
- C3 -
5AIG
4
?
A:
[2-124]
------------------------
T
P
I
-
E
T
V
T
A
F
I
-
A
-
H
-
W
N
S
-
G
D
--
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C
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E
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V
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-
W
H
N
I
-
P
-
M
-------
E
-
P
I
A
-
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P
-
A
M
R
A
A
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-
A
N
V
S-
Q
C
-
D
W
Q
V
-
H
A
I
A
--
A
N
G
A
T
V
L
T
E
R
T
D
G
F
--------
T
-
F
---------
T
---------
N
G
--
R
R
A
T
I
R
V
M
G
T
F
E
C
D
A
E
R
R
I
I
A
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Y
F
D
M
L
E
F
Q
R
E
F
A
G
---------
28
HHSearch
85.81
19%
-84
- C3 -
3FGY
2
?
A:
[2-133]
--------------------
M
S
T
Q
E
N
V
-
Q
I
V
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D
F
F
-
A
-
A
-
M
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-
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D
--
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G
L
L
A
V
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A
E
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I
E
-
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I
I
P
-
G
-
E
WPLA---
G
-
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R
-
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H
A
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A
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A
A
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A
-
S
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E
M
V
E
-
I
S
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Y
P
E
P
-
P
E
F
V
--
A
Q
G
E
R
V
L
V
V
G
F
A
T
G
--------
R
-
V
K--------
S
---------
T
N
--
R
T
F
E
D
D
W
V
F
A
I
T
V
R
-
K
S
K
V
T
S
I
R
E
Y
I
D
T
L
A
L
A
R
A
T
N
F
N
--------
33
HHSearch
83.17
14%
-95
- C3 -
2GEY
2
?
A:
[2-139]
---------------------
S
M
A
E
R
K
-
A
L
C
L
E
M
V
-
A
-
A
-
W
N
R
-
W
D
--
L
S
G
I
I
K
H
W
S
P
D
I
V
-
H
Y
S
E
-
D
-----------
N
E
V
-
S
S
A
-
D
M
V
K
L
M
E
G
G
-
L
-
K
A
F
P-
D
L
-
Q
L
E
V
-
K
S
I
M
--
A
E
E
D
R
V
A
L
R
I
T
V
T
A
--------
T
-
H
QGEFMGVQ-
P
---------
T
G
--
Q
R
V
S
W
H
L
V
E
E
L
R
F
V
-
D
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K
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H
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D
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R
P
L
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V
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L
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K
L
P
D
V
P
-
K
V
-
39
HHSearch
83.12
15%
-100
- C3 -
3F8H
5
?
A:
[14-149]
-------------------
N
L
Y
F
Q
G
M
N
-
D
T
I
A
R
Y
F
-
D
-
A
-
F
N
A
-
G
D
--
T
D
G
M
L
A
C
L
S
E
D
V
A
-
H
H
V
N
-
E
-
G
-------
N
-
I
R
V
-
G
K
E
-
K
F
A
A
F
C
A
H
M
-
S
-
H
C
Y
--
K
E
-
E
L
T
D
-
M
V
I
F
A
T
P
D
A
T
R
A
A
A
E
Y
T
V
N
G
--------
T
-
Y
---------
L
ATDEGLPEA
R
Q
--
Q
S
Y
K
L
P
A
G
S
F
F
D
L
R
-
D
G
L
I
T
R
V
T
T
Y
Y
N
L
S
D
W
I
K
Q
V
S
----------
23
HHSearch
83.10
16%
-93
- C3 -
4LGQ
2
?
A:
[6-139]
----------------------
M
D
T
S
K
-
A
V
I
Q
R
F
N
-
R
E
V
-
I
E
N
-
G
D
--
M
A
A
F
A
E
L
V
A
P
D
F
V
-
N
H
S
A
-
P
-
P
-------
G
-
V
S
P
-
G
P
D
-
G
F
A
G
F
F
T
G
M
-
L
H
P
A
L
S-
D
I
-
R
V
H
I
-
H
E
Q
I
--
E
E
N
G
K
V
V
T
R
K
T
I
E
A
--------
T
-
H
TGAFFGQP-
A
---------
S
G
--
K
R
I
A
I
H
A
M
D
I
V
V
V
R
-
D
G
K
Y
A
E
H
W
S
C
A
D
L
Y
G
A
L
A
Q
I
R
A
---------
44
Fugue
82.51
14%
-97
- C3 -
1NWW
2
LIMA_RHOER
A:
[5-149]
------IEQPRWASKDSA
A
G
A
A
S
T
P
D
E
-
K
I
V
L
E
F
M
-
D
-
A
-
L
T
S
N
-
D
--
A
A
K
L
I
E
Y
F
A
E
D
T
M
-
Y
Q
N
M
-
P
-
L
-------
P
-
P
A
Y
-
G
R
D
-
A
V
E
Q
T
L
A
G
L
F
T
-
V
M
S
--
I
D
-
A
V
E
T
-
F
H
I
G
--
S
S
N
G
L
V
Y
T
E
R
V
D
V
L
--------
R
A
L
---------
P
---------
T
G
--
K
S
Y
N
L
S
I
L
G
V
F
Q
L
T
-
E
G
K
I
T
G
W
R
D
Y
F
D
L
R
E
F
E
E
A
V
D
L
----
P
-
L
R
G
38
HHSearch
81.57
18%
-84
- C3 -
1SJW
1
?
A:
[2-141]
-----------------------
S
R
Q
T
-
E
I
V
R
R
M
V
-
S
-
A
-
F
N
T
-
G
R
--
T
D
D
V
D
E
Y
I
H
P
D
Y
L
-
N
P
A
T
L
E
-
H
-------
G
-
I
H
T
-
G
P
K
-
A
F
A
Q
L
V
G
W
V
-
R
-
A
T
F
S-
E
E
A
R
L
E
E
-
V
R
I
E
--
E
R
G
P
W
V
K
A
Y
L
V
L
Y
G
--------
R
-
H
VGRLVGMP-
P
---------
T
D
--
R
R
F
S
G
E
Q
V
H
L
M
R
I
V
-
D
G
K
I
R
D
H
R
D
W
P
D
F
Q
G
T
L
R
Q
L
G
D
P
W
P
D
D
-
E
G
-
36
HHSearch
81.00
15%
-97
- C3 -
4R9K
3
LIMA_RHOER
A:
[19-148]
--------------------
K
A
S
T
P
D
E
-
K
I
V
L
E
F
M
-
D
-
A
-
L
T
S
-
N
D
--
A
A
K
L
I
K
Y
F
A
E
D
T
M
-
Y
Q
N
M
-
P
-
L
-------
P
-
P
A
Y
-
G
R
D
-
A
V
E
Q
T
L
A
G
L
-
F
-
K
V
M
S-
I
D
-
A
V
E
V
-
F
H
I
G
--
S
S
K
G
L
V
F
T
E
R
V
D
V
L
--------
R
-
A
L--------
P
---------
T
G
--
K
S
Y
N
L
S
I
L
G
V
F
Q
L
T
-
D
G
K
I
T
G
W
R
D
Y
F
D
L
R
E
F
E
E
A
V
D
L
P
L
R
------
24
HHSearch
79.61
14%
-103
- C3 -
1NWW
2
LIMA_RHOER
A:
[19-148]
--------------------
A
A
S
T
P
D
E
-
K
I
V
L
E
F
M
-
D
-
A
-
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T
S
-
N
D
--
A
A
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Y
F
A
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D
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M
-
Y
Q
N
M
-
P
-
L
-------
P
-
P
A
Y
-
G
R
D
-
A
V
E
Q
T
L
A
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L
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F
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V
M
S-
I
D
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A
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--
S
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N
G
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V
Y
T
E
R
V
D
V
L
--------
R
-
A
L--------
P
---------
T
G
--
K
S
Y
N
L
S
I
L
G
V
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Q
L
T
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E
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K
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G
W
R
D
Y
F
D
L
R
E
F
E
E
A
V
D
L
P
L
R
------
50
Fugue
78.96
17%
-87
- C3 -
1SJW
1
?
A:
[2-143]
------------------------
S
R
Q
-
T
E
I
V
R
R
M
-
V
-
S
-
A
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G
R
--
T
D
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V
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Y
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P
D
Y
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P
A
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-
L
-
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-------
H
G
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T
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P
K
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A
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A
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SE
E
A
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E
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R
I
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E
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G
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W
V
K
A
Y
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L
Y
G
R
HVGRLVG
M
-
P
---------
P
---------
T
D
--
R
R
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L
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D
P
W
P
D
D
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W
R
34
HHSearch
78.20
19%
-74
- C3 -
2BNG
1
EPHG_MYCTU
A:
[13-139]
---------------------
E
T
T
E
A
I
-
R
A
V
E
A
F
L
-
N
-
A
-
L
Q
N
-
E
D
--
F
D
T
V
D
A
A
L
G
D
D
L
V
-
Y
E
N
V
-
G
-
F
-------
S
-
R
I
R
-
G
G
R
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R
T
A
T
L
L
R
R
M
-
Q
-
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R
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--
G
F
-
E
V
K
I
-
H
R
I
G
--
A
D
G
A
A
V
L
T
E
R
T
D
A
L
--------
I
-
I
-------------------
G
P
--
L
R
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Q
F
W
V
C
G
V
F
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V
D
-
D
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R
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Y
F
D
V
Y
D
M
F
K
G
L
L
R
G
L
V
A
-----
22
HHSearch
77.86
15%
-89
- C3 -
4H3U
14
?
A:
[25-154]
-----------------------
M
T
T
P
-
E
I
V
T
A
W
A
-
A
-
A
-
W
T
G
-
T
N
--
P
N
A
L
G
T
L
F
A
A
D
G
T
-
Y
V
D
H
-
A
I
G
-------
A
-
T
M
T
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G
R
E
-
Q
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K
A
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-
A
M
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E-
N
V
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V
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K
A
Y
--
R
A
G
D
H
V
T
I
E
A
V
Y
G
G
--------
H
-
I
-------------------
K
G
AP
T
P
F
A
V
P
M
A
T
L
L
R
T
R
-
G
E
E
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Q
D
Y
Y
S
L
S
S
V
L
A
Q
S
G
L
P
A
D
W
T
----
35
HHSearch
75.97
16%
-90
- C3 -
3KKG
4
?
A:
[6-144]
--------------------
P
I
E
-
Q
N
V
-
E
T
V
L
R
L
F
-
D
-
E
G
W
G
A
-
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D
V
W
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-
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H
-
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-
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-------
Q
-
A
V
E
-
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I
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A
I
A
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N
A
V
L
-
F
-
E
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F
P
-
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L
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E
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V
V
-
E
N
V
T
--
V
E
G
D
N
V
V
V
Q
A
R
L
T
G
--------
A
-
Q
DGPFLGVP-
P
---------
S
G
--
Q
M
V
D
V
P
D
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T
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-
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A
I
S
A
P
P
-------
30
HHSearch
75.65
14%
-86
* C3 *
3EBT
2
?
A:
[3-132]
-----------------------
S
N
N
M
-
Q
T
V
R
E
S
Y
-
E
-
A
-
F
H
R
-
R
D
--
L
P
G
V
L
A
A
L
A
P
D
V
R
-
W
T
H
P
-
D
-
G
MSPYGLG
G
-
T
K
H
-
G
H
D
-
E
V
I
A
F
I
R
H
V
-
P
-
T
H
I
A-
E
M
-
R
L
A
P
-
D
E
F
I
--
E
S
G
E
R
I
V
V
L
G
T
R
R
V
--------
T
-
A
---------
V
---------
N
G
--
R
S
A
T
L
K
F
V
H
V
W
R
F
E
-
N
G
R
A
V
T
F
E
D
H
F
D
T
A
E
M
I
R
L
I
T
A
---------
21
HHSearch
71.20
13%
-91
- C3 -
3K0Z
1
?
A:
[32-157]
---------------------
E
A
T
E
M
V
-
H
A
A
Q
R
F
Y
-
A
-
F
-
W
D
T
-
G
K
--
E
E
L
I
P
Q
T
V
T
E
N
F
F
-
D
H
T
L
-
P
-
K
-------
G
-
R
P
Q
-
G
T
E
-
G
L
K
F
A
A
Q
N
F
-
R
-
K
I
V
P-
N
I
-
H
C
E
I
-
E
D
L
L
--
V
V
G
D
K
V
T
A
R
L
S
F
T
G
--------
T
-
H
-------------------
N
D
--
K
K
I
D
F
F
A
I
D
I
L
H
V
K
-
D
G
K
I
T
E
D
W
H
L
E
D
N
L
T
L
K
Q
Q
L
G
L
I
A
-------
48
Fugue
69.62
12%
-84
- C3 -
3K0Z
1
?
A:
[9-157]
EVQLLKEMPKPK
A
M
T
I
D
P
S
L
S
Q
K
E
A
T
E
M
V
H
A
A
Q
R
F
-
Y
-
A
-
F
W
D
T
G
K
--
E
E
L
I
P
Q
T
V
T
E
N
F
F
-
D
H
T
L
-
P
-
K
-------
G
-
R
P
Q
-
G
T
E
-
G
L
K
F
A
A
Q
N
F
-
R
-
K
I
V
P-
N
I
-
H
C
E
I
-
E
D
L
L
--
V
V
G
D
K
V
T
A
R
L
S
F
T
G
--------
T
-
H
---------
N
---------
D
---
K
K
I
D
F
F
A
I
D
I
L
H
V
K
-
D
G
K
I
T
E
D
W
H
L
E
D
N
L
T
L
K
Q
Q
L
G
L
I
A
-------
27
HHSearch
69.60
12%
-77
- C3 -
3F9S
1
?
A:
[1-143]
------------------
G
M
S
I
S
S
K
A
K
-
E
I
L
T
Q
F
T
R
E
-
V
-
W
S
E
-
G
N
--
I
E
A
S
D
K
Y
I
A
P
K
Y
T
V
L
H
D
P
-
G
-
D
PWE----
G
-
R
E
L
-
D
V
A
-
G
Y
K
E
R
V
K
T
L
-
R
-
A
A
F
P
-
D
Q
-
C
F
D
I
-
Q
G
L
F
--
A
D
G
D
A
V
V
M
T
W
L
W
T
A
--------
T
-
H
KEDIPGFP-
S
---------
T
G
--
K
Q
I
K
M
S
G
A
T
V
Y
Y
F
D
-
G
N
R
L
T
G
H
W
Q
I
T
D
R
L
G
V
Y
Q
Q
L
R
Q
A
A
-------
40
HHSearch
68.42
13%
-78
- C3 -
3EC9
2
?
A:
[11-140]
----------------------
M
R
T
P
Y
-
Q
I
V
A
D
H
Y
-
A
-
A
-
S
D
R
-
H
D
--
P
A
A
M
M
A
D
I
A
P
A
I
E
-
W
T
E
M
-
A
-
G
FPC
A
---
G
-
T
Y
R
-
S
A
D
E
I
V
R
N
V
F
R
R
L
-
G
-
E
E
W
D-
G
Y
-
T
F
K
L
-
D
A
L
H
--
D
A
G
D
T
V
I
G
V
G
R
Y
S
G
--------
T
-
Y
R--------
R
---------
T
G
--
K
S
F
E
C
R
V
A
H
V
W
R
V
D
-
A
G
K
I
V
H
F
E
Q
F
T
D
T
L
L
V
A
Q
A
M
Q
P
---------
46
Fugue
67.69
14%
-77
- C3 -
2K54
-
?
A:
[1-123]
---------------------
M
N
S
E
I
E
-
L
P
V
Q
K
Q
L
-
E
-
A
-
Y
N
A
R
-
D
--
I
D
A
F
M
A
W
W
A
D
D
C
Q
-
Y
Y
A
F
-
P
-
A
-------
T
-
L
L
A
G
N
A
A
-
E
I
R
V
R
H
I
E
R
-
F
-
K
E
P
--
D
L
-
Y
G
E
L
-
L
T
R
V
--
I
V
G
N
V
V
I
D
H
E
T
V
T
R
--------
N
-
F
---------
P
---------
E
G
---
K
G
E
V
D
V
A
C
I
Y
E
V
E
-
N
G
R
I
A
K
A
W
F
K
I
G
E
P
R
I
V
S
Q
K
S
----------