@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3383c: (2016-05-19 )
MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLATMAGYHLGWWNADRSTAAGSSGKYFRAALVYAAAAACGGDVGDATPVSAAVELVHNFTLLHDDVMDGDATRRGRPTVWSVWGVGVAILLGDALHATAVRILTGLTDECVAVRAIRRLQMSCLDLCIGQFEDCLLEGQPEVTVDDYLRMAAGKTAALTGCCCALGALVANADDATIAALERFGHELGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAATELAALYQAPAAMTASDVERATALVKVAGGGHVAQRCADERIQAAIAALPDAVRSPDLIALSQLICRREC
Atome Classification :
(44 SA)
.........10........20........30........40---.-.......50........60........70........80......-..90....-----..---..100.......110-......--..120.......130.....--------..140...-...--.150.--...----.-----..160.-.-----.--.--------.----.--.170.......180-..------------....--.190.......200..-.....210...-....-220.......230.......240.......250.......260......-.270........-280.-.......290-----.------..--.....300.......310......---.320.------..---.---.---.-------.---330.-......340.......350
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MG
G
V
L
T
L
D
A
A
F
LGS
V
P
A
D
L
G
K
A
L
L
E
R
ARA
D
C
G
P
V
L
H
R
A
I
E
S
---
M
-
R
E
P
L
A
T
M
AGYH
L
G
W
WNADRSTAAGSSG
K
Y
F
R
A
A
L
V
Y
A
A
A
A
ACGGD-VGDAT
P
V
S
-----
A
A
---
V
E
L
V
H
N
F
T
L
L
HDDV--MDGDAT--RRGRP
T
V
W
S
V
W
G
V
G
V
A
I
L
LG--------D
A
L
H
A
T
A
V
-
R
I
L
--TGL
T
D
--
E
C
V
----
A
-----
V
R
A
I
R
R
-
L
-----
Q
--
M
--------
S
----
C
--
L
D
L
C
I
G
Q
F
E
D
C
L
LE-GQ------------PEV
T
--
V
D
D
Y
L
R
M
AAGK
T
A
A
L
T
-
G
C
C
C
A
L
G
A
L
VA-NAD
D
-
A
T
I
A
A
L
E
R
F
G
H
E
L
G
L
A
F
Q
C
V
D
D
L
I
GIWGDPGVTGKPV
G
N
D
L
A
R
RKAT
L
P
-
V
V
A
-ALNS
R
S
E
A
-
A
-
T
E
-
L
A
A
L
Y
QAPA------A------M
T
--
A
S
D
V
E
R
A
T
A
L
V
K
VAGG
G
H
V
A
Q
R
C
A
---
D
E
R
I
Q
------
A
A
---
I
---
A
---A-------L---
P
D
AV-RS
P
D
L
I
A
L
S
Q
L
I
CRREC-
53
HHSearch
97.64
42%
-115
- C1 -
3NF2
6
?
A:
[4-341]
------------------
D
V
T
A
L
L
E
R
G
R
T
L
A
T
P
V
L
R
A
A
V
D
R
---
L
-
A
P
P
M
D
T
V
A
A
Y
H
F
G
W
I
D
A
Q
G
N
P
A
D
G
D
G
G
K
A
V
R
P
A
L
A
V
L
S
A
E
V
T
G
A
A
-
P
E
V
G
V
P
G
A
-----
V
A
---
V
E
L
V
H
N
F
S
L
L
H
D
D
L
--
M
D
G
D
E
Q
--
R
R
H
R
D
T
V
W
K
V
H
G
P
A
Q
A
I
L
V
G
--------
D
A
L
F
A
L
A
N
-
E
V
L
--
L
E
L
G
T
--
V
E
-----
A
-----
G
R
A
T
R
R
-
L
-----
T
--
K
--------
A
----
S
--
R
S
L
I
D
G
Q
A
Q
D
I
S
Y
E
-
H
R
------------
D
R
V
S
--
V
E
E
C
L
E
M
E
G
N
K
T
G
A
L
L
-
A
C
A
S
S
I
G
A
V
L
G
-
G
A
D
E
-
R
T
A
D
T
L
E
K
Y
G
Y
H
L
G
L
A
F
Q
A
V
D
D
L
L
G
I
W
G
D
P
D
A
T
G
K
Q
T
W
S
D
L
R
Q
R
K
K
S
L
P
-
V
V
A
-
A
L
A
A
G
G
A
A
-
S
-
E
R
-
L
G
E
I
L
T
A
D
A
K
ASDFA
N
------
F
S
--
E
E
E
F
A
A
R
A
A
L
I
E
E
A
G
G
R
E
W
T
A
D
E
A
---
R
R
Q
H
T
------
I
A
---
I
---
E
A
L
D
A
-------
V
---
D
M
P
D
R
V
R
D
R
F
T
A
L
A
D
F
V
V
V
----
1
PsiBlast_PDB
94.34
43%
-113
- C1 -
3NF2
6
?
A:
[7-328]
---------------------
A
L
L
E
R
G
R
T
L
A
T
P
V
L
R
A
A
V
D
R
---
L
-
A
P
P
M
D
T
V
A
A
Y
H
F
G
W
I
D
A
Q
G
N
P
A
D
G
D
G
G
K
A
V
R
P
A
L
A
V
L
S
A
E
V
T
G
A
A
-
P
E
V
G
V
P
G
A
-----
V
A
---
V
E
L
V
H
N
F
S
L
L
H
D
D
L
--
M
D
G
D
E
Q
--
R
R
H
R
D
T
V
W
K
V
H
G
P
A
Q
A
I
L
V
G
--------
D
A
L
F
A
L
A
N
-
E
V
L
--
L
E
L
G
---
T
V
E
----
A
-----
G
R
A
T
R
R
-
L
-----
T
--
K
--------
A
----
S
--
R
S
L
I
D
G
Q
A
Q
D
I
S
Y
E
-
H
R
------------
D
R
V
S
--
V
E
E
C
L
E
M
E
G
N
K
T
G
A
L
L
-
A
C
A
S
S
I
G
A
V
L
G
-
G
A
D
E
-
R
T
A
D
T
L
E
K
Y
G
Y
H
L
G
L
A
F
Q
A
V
D
D
L
L
G
I
W
G
D
P
D
A
T
G
K
Q
T
W
S
D
L
R
Q
R
K
K
S
L
P
-
V
V
A
-
A
L
A
A
G
G
A
A
-
S
-
E
R
-
L
G
E
I
L
T
A
D
A
------
K
ASDFAN
F
S
--
E
E
E
F
A
A
R
A
A
L
I
E
E
A
G
G
R
E
W
T
A
D
E
A
---
R
R
Q
H
T
------
I
A
---
I
---
E
---
A
-------
L
----
D
A
V
-
D
M
P
D
R
V
------------
54
HHSearch
79.71
31%
-107
* C1 *
1WY0
2
?
A:
[4-341]
----------------
Y
E
E
L
F
A
R
I
K
E
K
A
K
L
I
D
E
K
I
F
E
L
I
P
E
---
K
D
P
R
V
L
Y
E
A
A
R
H
Y
P
-----------
L
A
G
G
K
R
V
R
P
F
V
V
L
T
S
T
E
A
V
G
G
D
-
P
L
R
A
I
Y
P
A
-----
V
A
---
I
E
L
I
H
N
Y
S
L
V
H
D
D
I
--
M
D
M
D
E
T
--
R
R
G
K
P
T
V
H
R
I
W
G
V
N
M
A
I
L
A
G
--------
D
L
L
F
S
K
A
F
-
E
A
V
--
A
R
A
E
I
--
P
P
E
K
---
K
-----
A
R
V
L
E
V
-
I
-----
V
--
K
--------
A
----
S
--
N
E
L
C
E
G
Q
A
R
D
L
E
F
E
-
K
K
------------
S
T
V
T
--
I
E
E
Y
M
E
M
I
S
G
K
T
G
A
L
F
-
E
A
S
A
K
V
G
G
I
I
G
-
T
D
N
E
-
E
Y
I
K
A
L
S
S
W
G
R
N
V
G
I
A
F
Q
I
W
D
D
V
L
D
L
I
A
D
E
K
K
L
G
K
P
V
G
S
D
I
R
K
G
K
K
T
L
I
-
V
A
H
-
F
F
E
N
A
D
E
K
-
D
K
Q
R
-
F
L
K
I
F
G
K
---------------
D
I
--
K
S
D
V
M
E
A
I
D
L
L
K
K
Y
G
S
I
D
Y
A
A
E
I
A
---
K
D
M
I
K
------
K
A
---
N
---
E
A
L
R
I
-------
L
---
P
K
S
K
-
A
R
M
D
L
E
L
L
A
K
F
I
V
E
R
E
--
2
PsiBlast_PDB
75.12
33%
-114
- C1 -
1WY0
2
?
A:
[46-341]
------------------------------------------------------------------------
G
K
R
V
R
P
F
V
V
L
T
S
T
E
A
V
G
G
D
-
P
L
R
A
I
Y
P
A
-----
V
A
---
I
E
L
I
H
N
Y
S
L
V
H
D
D
I
--
M
D
M
D
E
T
--
R
R
G
K
P
T
V
H
R
I
W
G
V
N
M
A
I
L
A
G
--------
D
L
L
F
S
K
A
F
-
E
A
V
A
R
A
E
I
P
P
--
E
K
K
----
A
------
R
V
L
E
V
-
I
-----
V
--
K
--------
A
----
S
--
N
E
L
C
E
G
Q
A
R
D
L
E
F
E
-
K
K
------------
S
T
V
T
--
I
E
E
Y
M
E
M
I
S
G
K
T
G
A
L
F
-
E
A
S
A
K
V
G
G
I
I
G
-
T
D
N
E
-
E
Y
I
K
A
L
S
S
W
G
R
N
V
G
I
A
F
Q
I
W
D
D
V
L
D
L
I
A
D
E
K
K
L
G
K
P
V
G
S
D
I
R
K
G
K
K
T
L
I
-
V
A
H
-
F
F
E
N
A
D
E
K
-
D
-
K
Q
R
F
L
K
I
F
G
K
-----------------D
I
K
S
D
V
M
E
A
I
D
L
L
K
K
Y
G
S
I
D
Y
A
A
E
I
A
---
K
D
M
I
K
------
K
A
---
N
---
E
---
A
L
RI----
L
---
P
K
S
K
-
A
R
M
D
L
E
L
L
A
K
F
I
V
E
R
E
--
58
HHSearch
72.75
30%
-111
- C1 -
4DHD
3
?
A:
[12-335]
-------------------------
K
Y
G
A
E
V
E
K
A
L
V
R
Y
L
S
I
---
G
L
A
E
D
F
R
E
A
V
L
Y
Q
V
-----------
K
T
G
G
K
R
L
R
P
L
L
T
L
A
A
A
E
A
V
S
G
Q
-
W
R
P
A
L
P
A
A
-----
A
I
---
V
E
L
I
H
N
Y
S
L
I
Y
D
D
I
--
I
D
R
G
D
V
--
R
R
G
L
P
T
V
R
K
A
F
G
D
N
A
A
I
L
V
G
--------
I
W
Y
R
E
A
I
E
-
E
A
V
--
L
D
T
P
K
---------
P
-----
T
L
F
A
K
E
-
V
-----
A
--
E
--------
V
----
I
--
K
A
I
D
E
G
E
R
L
D
I
L
F
E
-
A
A
GRSD
P
Y
F
V
Q
A
RW
R
E
V
T
--
L
D
D
Y
I
K
M
V
S
L
K
T
G
A
L
I
-
A
A
A
A
K
W
G
V
L
S
V
-
S
D
D
R
-
G
L
A
E
A
A
W
N
F
G
M
A
A
G
V
A
F
Q
I
I
D
D
V
L
D
I
Y
G
-------
E
I
G
K
D
I
K
E
H
K
R
G
N
A
V
V
A
V
-
A
L
S
H
L
G
E
G
-
E
R
R
R
-
L
L
E
I
L
A
R
E
-------
V
------
V
E
--
E
A
D
V
R
E
A
V
A
L
L
D
S
V
G
A
R
E
E
A
L
R
L
A
---
A
R
Y
R
E
------
E
A
---
E
---
R
---
H
-------
L
---
A
K
I
P
-
N
N
G
T
L
K
E
L
L
D
F
I
V
A
R
E
--
47
HHSearch
72.70
26%
-103
- C1 -
3AQB
3
HEXB_MICLU
B:
[5-325]
------------------
S
Y
K
A
F
L
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
Q
S
---
D
-
S
E
T
I
N
K
A
A
H
H
I
L
-----------
S
S
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
L
N
D
T
Q
-
K
D
D
L
I
R
T
A
-----
V
S
---
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
--
I
D
N
S
D
M
--
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
--------
H
F
L
L
A
R
A
L
-
Q
N
I
--
A
T
I
N
N
---------------
S
K
F
H
Q
I
-
F
-----
S
--
K
--------
T
----
I
--
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
-
F
N
------------
Y
P
V
S
--
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
-
E
A
S
C
H
L
G
A
L
S
S
-
Q
L
D
E
-
Q
S
T
Y
H
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
-
L
M
A
-
A
I
A
N
L
K
E
Q
-
D
D
D
K
-
L
E
A
V
V
K
H
L
T
S-----
T
------
S
D
--
D
E
V
Y
Q
Y
I
V
S
Q
V
K
Q
Y
G
-
I
E
P
A
E
L
L
S
---
R
K
Y
G
D
------
K
A
---
K
Y
H
L
S
---
Q
-------
L
---
Q
D
S
N
-
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
-
52
HHSearch
67.74
28%
-98
- C1 -
3PKO
2
?
A:
[15-333]
-----------------
W
R
Q
F
P
Q
V
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
Q
L
---
D
-
N
Q
P
I
H
H
K
I
L
A
L
L
-----------
K
S
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
F
G
N
A
A
T
P
A
Q
L
Q
A
G
A
-----
A
A
---
I
E
I
L
H
V
G
T
L
I
H
D
D
V
--
I
D
D
S
P
T
--
R
R
G
V
R
T
I
Q
M
T
Y
G
Q
R
N
A
I
Y
A
G
--------
D
F
M
F
T
V
Y
F
-
D
Q
V
--
L
K
S
T
T
--
D
------------
R
S
L
I
Q
N
-
H
-----
I
--
D
--------
A
----
M
--
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
-
Y
R
------------
E
D
I
T
--
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
-
A
L
S
C
Y
Q
G
A
Q
L
A
-
G
A
P
Q
-
S
V
I
D
R
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
D
Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
R
S
G
V
Y
S
L
P
-
L
L
L
-
S
L
S
H
A
P
R
-----
D
-
F
H
K
L
L
K
K
K
Q
------
A
------
M
T
--
L
E
D
I
K
H
V
Q
A
L
V
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
---
Q
D
Y
T
D
------
R
A
---
L
T
L
I
Q
---
Q
-------
L
---
P
V
G
S
-
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
D
--
69
Fugue
67.68
25%
-96
- C1 -
3AQB
3
HEXB_MICLU
B:
[5-325]
------------------
S
Y
K
A
F
L
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
Q
S
---
D
-
S
E
T
I
N
K
A
A
H
H
I
L
S
-----------
S
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
L
N
D
T
Q
-
K
D
D
L
I
R
T
A
-----
V
S
---
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
--
I
D
N
S
D
M
--
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
--------
H
F
L
L
A
R
A
L
-
Q
N
I
--
A
T
I
N
N
---------------
S
K
F
H
Q
I
-
F
-----
S
--
K
--------
T
----
I
--
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
-
F
N
------------
Y
P
V
S
--
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
-
E
A
S
C
H
L
G
A
L
S
S
-
Q
L
D
E
-
Q
S
T
Y
H
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
-
L
M
A
-
A
I
A
N
L
K
E
Q
D
D
-
D
K
-
L
E
A
V
V
K
H
L
T
------
S
------
T
S
--
D
D
E
V
Y
Q
Y
I
V
S
Q
V
K
Q
Y
G
I
E
P
A
E
L
L
S
---
R
K
Y
G
D
------
K
A
---
K
---
Y
---
H
-------
L
S
Q
L
Q
D
S
N
-
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
-
44
HHSearch
64.09
25%
-111
- C1 -
4JXY
2
?
A:
[18-345]
---------
L
Y
F
Q
S
M
D
L
D
H
I
L
S
L
A
E
P
D
M
L
A
V
N
Q
L
I
Q
K
Q
V
N
S
---
D
-
V
S
L
I
N
Q
L
G
F
Y
I
V
-----------
N
S
G
G
K
R
L
R
P
L
L
T
V
L
A
A
R
A
L
N
I
Q
-
T
E
Q
H
H
T
L
A
-----
A
I
---
I
E
F
I
H
T
A
T
L
L
H
D
D
V
--
V
D
-----------
T
A
N
E
V
F
G
N
Q
A
S
V
L
V
G
--------
D
F
L
Y
T
R
S
F
-
Q
M
M
--
V
T
L
D
S
---------------
M
R
V
M
Q
I
-
L
-----
S
--
D
--------
A
----
T
--
N
V
I
A
E
G
E
V
L
Q
L
M
N
C
-
N
D
------------
P
D
T
T
--
E
E
S
Y
M
E
V
I
Y
S
K
T
A
R
L
F
-
E
A
A
T
L
L
A
G
V
L
T
-
K
Q
S
E
-
A
I
E
N
A
M
Q
D
Y
G
K
Y
L
G
T
A
F
Q
L
V
D
D
I
M
D
Y
A
----------
G
D
D
L
A
E
G
K
P
T
L
P
-
L
L
Y
-
A
M
W
H
G
N
E
Q
-
Q
T
A
I
-
I
R
E
A
I
E
T
G
--------------
N
G
--
M
D
N
L
T
P
I
L
E
T
M
E
Q
T
G
A
L
T
Y
T
K
Q
Q
A
---
L
K
A
S
Q
------
Q
A
---
I
---
D
A
L
S
P
-------
I
---
E
E
S
V
-
Y
K
E
A
L
I
G
L
A
H
I
S
V
E
R
V
A
-
20
PsiBlast_PDB
63.56
30%
-102
- C1 -
3PKO
2
?
A:
[53-333]
----------------------------------------------------------------------
S
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
F
G
N
A
-----
A
T
P
A
Q
L
Q
A
G
A
A
A
---
I
E
I
L
H
V
G
T
L
I
H
D
D
V
--
I
D
D
S
P
T
--
R
R
G
V
R
T
I
Q
M
T
Y
G
Q
R
N
A
I
Y
A
G
--------
D
F
M
F
T
V
Y
F
D
Q
V
L
--
K
S
T
T
D
--
R
S
L
----
I
-----
Q
N
H
I
D
A
-
M
-----
H
--
R
------------------
I
L
Q
G
E
L
H
Q
M
D
L
N
-
Y
R
------------
E
D
I
T
--
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
-
A
L
S
C
Y
Q
G
A
Q
L
A
-
G
A
P
Q
-
S
V
I
D
R
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
D
Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
---
R
S
G
V
Y
-
S
L
P
-
L
L
L
S
L
S
H
A
-
P
-
R
D
-
F
H
K
L
L
K
K
K
Q
------
A
------
M
T
--
L
E
D
I
K
H
V
Q
A
L
V
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
---
Q
D
Y
T
D
------
R
A
L
T
L
I
---
Q
---
Q
-------
L
---
P
V
G
S
-
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
D
--
48
HHSearch
63.43
28%
-109
- C1 -
4LOB
4
?
A:
[34-346]
----------------------
P
V
A
T
D
F
A
A
M
D
H
L
I
N
E
G
I
S
S
---
K
-
V
G
L
V
M
S
V
S
K
H
V
V
-----------
E
A
G
G
K
R
M
R
P
I
M
C
L
L
A
A
R
A
C
D
L
D
N
M
Q
N
A
Q
R
L
A
-----
A
I
---
I
E
M
L
H
T
A
T
L
V
H
D
D
V
--
V
D
----------------
W
N
N
Q
T
A
V
L
V
G
--------
D
F
L
I
A
R
A
F
-
D
L
L
--
V
D
L
N
N
---------------
M
T
L
L
K
D
-
F
-----
S
--
T
--------
G
----
T
--
C
E
I
A
E
G
E
V
L
Q
L
Q
S
Q
-
H
Q
------------
P
D
T
T
--
E
E
T
Y
L
K
I
I
H
G
K
T
S
R
L
F
-
E
L
A
T
E
G
A
A
I
L
A
-
G
Q
E
--
A
Y
R
E
P
L
R
L
F
A
G
H
F
G
N
A
F
Q
I
I
D
D
I
L
D
Y
T
S
D
A
E
T
L
G
K
N
I
G
D
D
L
M
E
G
K
P
T
L
P
-
L
I
S
-
A
L
A
H
S
T
G
E
-
E
H
A
I
-
I
R
R
S
I
A
T
G
---------------
G
--
V
D
Q
L
P
K
V
I
E
I
V
Q
K
S
G
A
L
D
Y
C
Q
R
R
A
---
Q
E
E
T
E
------
A
A
---
L
Q
A
L
S
---
I
-------
L
---
P
D
T
P
-
Y
R
Q
A
L
I
N
L
T
R
L
A
L
H
R
I
--
12
PsiBlast_PDB
62.42
32%
-96
- C1 -
4GP1
3
?
A:
[43-320]
----------------------------------------------------------------------
T
G
G
K
R
L
R
P
L
L
T
L
A
A
A
E
A
V
S
G
Q
-
W
R
P
A
L
P
A
A
-----
A
I
---
V
E
L
I
H
N
Y
S
L
I
Y
D
D
I
--
I
D
R
G
D
V
--
R
R
G
L
P
T
V
R
K
A
F
G
D
N
A
A
I
L
V
G
I
W
Y
R
E
A
I
E
E
A
V
L
D
T
P
K
-
P
T
L
--
F
A
-
K
E
--
V
A
E
----
V
-----
I
K
A
I
D
E
G
E
-----
R
--
L
--------
D
----
I
--
L
F
E
A
A
G
R
S
D
P
Y
F
V
Q
-
A
R
W-----------
R
E
V
T
--
L
D
D
Y
I
K
M
V
S
L
K
T
G
A
L
I
-
A
A
A
A
K
W
G
V
L
S
V
-
S
D
D
R
-
G
L
A
E
A
A
W
N
F
G
M
A
A
G
V
A
F
Q
I
I
D
D
V
L
D
I
Y
G
-------
E
I
G
K
D
I
K
E
H
K
R
G
N
A
-
V
V
A
V
A
L
S
H
L
G
E
G
-
E
-
R
R
-
R
L
L
E
I
L
A
R
E
------
V
------
V
E
--
E
A
D
V
R
E
A
V
A
L
L
D
S
V
G
A
R
E
E
A
L
R
L
A
A
R
Y
R
E
E
A
E
------
R
H
---
L
---
A
---
K
-------
I
---
P
N
---------------------
13
PsiBlast_PDB
62.15
32%
-92
- C1 -
4GP2
5
?
A:
[43-320]
----------------------------------------------------------------------
T
G
G
K
R
L
R
P
L
L
T
L
A
A
A
E
A
V
S
G
Q
-
W
R
P
A
L
P
A
A
-----
A
I
---
V
E
L
I
H
N
Y
S
L
I
Y
D
D
I
--
I
D
R
G
D
V
--
R
R
G
L
P
T
V
R
K
A
F
G
D
N
A
A
I
L
V
G
I
W
Y
R
E
A
I
E
E
A
V
L
D
T
P
K
-
P
T
L
--
F
A
-
K
E
--
V
A
E
----
V
-----
I
K
A
I
D
E
G
E
-----
R
--
L
--------
D
----
I
--
L
F
E
A
A
G
R
S
D
P
Y
F
V
Q
-
A
R
W-----------
R
E
V
T
--
L
D
D
Y
I
K
M
V
S
L
K
T
G
A
L
I
-
A
A
A
A
K
W
G
V
L
S
V
-
S
D
D
R
-
G
L
A
E
A
A
W
N
F
G
M
A
A
G
V
A
F
Q
I
I
D
D
V
L
D
I
Y
G
D
P
K
K
F
G
K
E
I
G
K
D
I
K
E
H
K
R
G
N
A
-
V
V
A
V
A
L
S
H
L
G
E
G
-
E
-
R
R
-
R
L
L
E
I
L
A
R
E
------
V
------
V
E
--
E
A
D
V
R
E
A
V
A
L
L
D
S
V
G
A
R
E
E
A
L
R
L
A
A
R
Y
R
E
E
A
E
------
R
H
---
L
---
A
---
K
-------
I
---
P
N
---------------------
11
PsiBlast_PDB
61.11
32%
-96
- C1 -
4DHD
3
?
A:
[43-320]
----------------------------------------------------------------------
T
G
G
K
R
L
R
P
L
L
T
L
A
A
A
E
A
V
S
G
Q
-
W
R
P
A
L
P
A
A
-----
A
I
---
V
E
L
I
H
N
Y
S
L
I
Y
D
D
I
--
I
D
R
G
D
V
--
R
R
G
L
P
T
V
R
K
A
F
G
D
N
A
A
I
L
V
G
I
W
Y
R
E
A
I
E
E
A
V
L
D
T
P
K
-
P
T
L
--
F
A
-
K
E
--
V
A
E
----
V
-----
I
K
A
I
D
E
G
E
-----
R
--
L
--------
D
----
I
--
L
F
E
A
A
G
R
S
D
P
Y
F
V
Q
-
A
R
W-----------
R
E
V
T
--
L
D
D
Y
I
K
M
V
S
L
K
T
G
A
L
I
-
A
A
A
A
K
W
G
V
L
S
V
-
S
D
D
R
-
G
L
A
E
A
A
W
N
F
G
M
A
A
G
V
A
F
Q
I
I
D
D
V
L
D
I
Y
G
-------
E
I
G
K
D
I
K
E
H
K
R
G
N
A
-
V
V
A
V
A
L
S
H
L
G
E
G
-
E
-
R
R
-
R
L
L
E
I
L
A
R
E
------
V
------
V
E
--
E
A
D
V
R
E
A
V
A
L
L
D
S
V
G
A
R
E
E
A
L
R
L
A
A
R
Y
R
E
E
A
E
------
R
H
---
L
---
A
---
K
-------
I
---
P
N
---------------------
46
HHSearch
60.17
28%
-114
- C1 -
3OYR
1
?
A:
[20-343]
------------
K
S
G
S
V
D
R
L
V
R
L
A
E
A
D
M
A
G
V
N
R
L
I
T
D
R
M
Q
S
---
D
-
V
A
I
I
P
A
L
A
E
H
L
I
-----------
A
A
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
L
A
G
A
D
-
N
D
H
F
Q
K
L
A
-----
A
A
---
V
E
F
I
H
T
A
T
L
L
H
D
D
V
--
V
-----------
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
--------
D
F
L
F
A
R
A
F
-
E
L
M
--
V
E
T
N
S
---------------
M
K
A
L
E
I
-
L
-----
A
--
R
--------
A
----
S
--
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
-
H
D
------------
L
N
L
S
--
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
-
A
A
A
S
E
A
G
A
V
S
A
-
G
V
D
V
-
A
K
S
E
A
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
-------------------
A
T
L
P
-
L
L
L
-
A
I
A
R
S
G
P
R
E
A
-
E
F
-
W
E
R
A
I
G
-----------------
T
--
E
A
D
F
R
R
A
R
E
L
I
I
G
S
G
A
L
D
A
T
L
D
L
A
---
A
D
Y
A
D
------
K
A
---
K
A
A
L
A
---
M
-------
F
---
P
A
N
D
-
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
---
55
HHSearch
60.11
27%
-88
- C1 -
1WMW
-
?
A:
[5-328]
-----------------------
P
E
A
I
R
Q
A
L
Q
E
R
L
L
A
R
L
D
H
---
P
-
D
P
L
Y
R
D
L
L
Q
D
Y
P
-----------
R
R
G
G
K
M
L
R
G
L
L
T
V
Y
S
A
L
A
H
G
A
P
-
L
E
A
G
L
E
A
A
-----
T
A
---
L
E
L
F
Q
N
W
V
L
V
H
D
D
I
--
E
D
G
S
E
E
--
R
R
G
R
P
A
L
H
R
L
H
P
M
P
L
A
L
N
A
G
--------
D
A
M
H
A
E
M
W
-
G
L
L
--
A
E
G
L
A
--
R
G
L
F---
P
-----
P
E
V
L
L
E
-
F
-----
H
--
E
--------
V
----
V
--
R
R
T
A
Y
G
Q
H
L
D
L
L
W
T
-
L
G
GT----------
F
D
L
R
--
P
E
D
Y
F
R
M
V
A
H
K
A
A
Y
Y
T
A
V
A
P
L
R
L
G
A
L
L
A
-
G
K
T
P
-
P
--
A
A
Y
E
E
G
G
L
R
L
G
T
A
F
Q
I
V
D
D
V
L
N
L
E
G
G
E
-
A
Y
G
K
E
R
A
G
D
L
Y
E
G
K
R
T
L
I
-
L
L
R
-
F
L
E
E
A
P
P
E
-
E
R
A
R
-
A
L
A
L
L
A
L
P
R
E-----
A
------
K
P
--
E
A
E
V
G
W
L
L
E
R
L
L
A
S
R
A
L
A
W
A
K
A
E
A
---
K
R
L
Q
A
------
E
G
---
L
---
A
---
L
L
E
AAFQD
L
---
P
G
K
E
-
A
L
D
H
L
R
G
L
L
A
A
L
V
E
R
---
26
PsiBlast_CBE
59.31
32%
-92
- C1 -
4GP2
5
?
B:
[43-320]
----------------------------------------------------------------------
T
G
G
K
R
L
R
P
L
L
T
L
A
A
A
E
A
V
S
G
Q
-
W
R
P
A
L
P
A
A
-----
A
I
---
V
E
L
I
H
N
Y
S
L
I
Y
D
D
I
--
I
D
R
G
D
V
--
R
R
G
L
P
T
V
R
K
A
F
G
D
N
A
A
I
L
V
G
I
W
Y
R
E
A
I
E
E
A
V
L
D
T
P
K
-
P
T
L
--
F
A
-
K
E
--
V
A
E
----
V
-----
I
K
A
I
D
E
G
E
-----
R
--
L
--------
D
----
I
--
L
F
E
A
A
G
R
S
D
P
Y
F
V
Q
-
A
R
W-----------
R
E
V
T
--
L
D
D
Y
I
K
M
V
S
L
K
T
G
A
L
I
-
A
A
A
A
K
W
G
V
L
S
V
-
S
D
D
R
-
G
L
A
E
A
A
W
N
F
G
M
A
A
G
V
A
F
Q
I
I
D
D
V
L
D
I
Y
G
D
------
E
I
G
K
D
I
K
E
H
K
R
G
N
A
-
V
V
A
V
A
L
S
H
L
G
E
G
-
E
-
R
R
-
R
L
L
E
I
L
A
R
E
------
V
------
V
E
--
E
A
D
V
R
E
A
V
A
L
L
D
S
V
G
A
R
E
E
A
L
R
L
A
A
R
Y
R
E
E
A
E
------
R
H
---
L
---
A
---
K
-------
I
---
P
N
---------------------
75
Fugue
59.28
27%
-105
- C1 -
3OYR
1
?
A:
[20-343]
------------
K
S
G
S
V
D
R
L
V
R
L
A
E
A
D
M
A
G
V
N
R
L
I
T
D
R
M
Q
S
---
D
-
V
A
I
I
P
A
L
A
E
H
L
I
A
-----------
A
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
L
A
G
A
D
-
N
D
H
F
Q
K
L
A
-----
A
A
---
V
E
F
I
H
T
A
T
L
L
H
D
D
V
--
V
V
A
A
H
-----------
L
I
W
G
G
A
Q
S
V
L
V
G
--------
D
F
L
F
A
R
A
F
-
E
L
M
--
V
E
T
N
S
---------------
M
K
A
L
E
I
-
L
-----
A
--
R
--------
A
----
S
--
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
-
H
D
------------
L
N
L
S
--
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
-
A
A
A
S
E
A
G
A
V
S
A
-
G
V
D
V
-
A
K
S
E
A
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
-------------------
Y
A
T
L
P
-
L
L
L
-
A
I
A
R
S
G
P
R
-
E
-
A
E
-
F
W
E
R
A
I
G
T
E
------------------
A
D
F
R
R
A
R
E
L
I
I
G
S
G
A
L
D
A
T
L
D
L
A
---
A
D
Y
A
D
------
K
A
---
K
---
A
---
A
-------
L
---
A
M
F
P
-
A
N
D
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
30
PsiBlast_CBE
56.85
31%
-105
- C1 -
3Q2Q
5
?
A:
[74-350]
------------------------------------------------------------------------
G
K
R
F
R
P
--
M
F
A
L
L
A
S
E
F
G
E
-
K
P
L
S
E
N
V
I
-----
K
A
A
V
V
V
E
I
T
H
L
A
T
L
Y
H
D
D
V
--
M
D
E
A
---------
S
A
N
A
R
W
D
N
S
V
A
I
L
A
G
--------
D
I
L
L
A
H
A
S
-
G
L
M
--
S
Q
L
G
T
--
D
T
V
----
A
----------
H
-
F
-----
A
--
E
--------
T
----
F
--
G
E
L
V
T
G
Q
M
R
E
T
V
----
G
------------
P
R
D
T
D
P
I
E
H
Y
T
N
V
I
R
E
K
T
G
V
L
I
-
A
S
A
G
Y
L
G
A
M
H
A
-
G
A
A
P
-
E
H
I
D
A
L
K
N
F
G
A
A
V
G
M
I
F
Q
I
V
D
D
I
I
D
I
F
S
E
T
H
----
T
P
G
T
D
L
R
E
G
V
F
T
L
P
-
V
L
Y
-
A
L
R
E
D
T
P
V
-
G
-
A
E
-
L
R
D
I
L
T
G
P
L
------
E
------
D
D
--
E
T
-
V
N
H
V
L
E
L
L
S
Q
S
G
G
---
R
Q
A
A
L
---
D
E
V
Y
R
Y
M
D
I
A
N
A
E
---
L
---
D
---
R
-------
L
---
P
D
S
T
-
V
K
E
A
L
R
N
L
A
T
F
T
V
K
R
---
14
PsiBlast_PDB
56.13
33%
-121
- C1 -
5E8L
-
GGPP1_ARATH
A:
[22-276]
---------------------------------
L
V
N
K
A
L
D
S
A
V
P
L
-
R
E
P
L
K
I
H
E
A
M
R
Y
S
L
L
---------
A
G
G
K
R
V
R
P
V
L
C
I
A
A
C
E
L
V
G
G
E
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
I
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
K
V
F
G
E
D
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
L
--
A
S
A
T
S
--
S
D
V
----
V
S
P
V
R
V
V
R
A
V
G
E
-
L
-----
A
K
A
I
--------
G
----
T
--
E
G
L
V
A
G
Q
V
V
D
I
S
-------------------
V
G
--
L
E
H
L
E
F
I
H
L
H
K
T
A
A
L
L
-
E
A
S
A
V
L
G
A
I
V
G
-
G
G
S
D
-
D
E
I
E
R
L
R
K
F
A
R
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
------------
L
I
A
D
K
L
T
Y
P
-
K
I
M
-
G
L
E
K
S
R
E
F
-
A
-
E
K
-
L
---------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
53.01
32%
-100
- C1 -
3KRF
4
?
A:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
A
V
Q
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
G
E
L
A
V
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
----------------
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
52.06
32%
-92
- C1 -
3KRP
3
?
D:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
AVQ
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
GELAV
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
S
S
K
E
L
G
K
-----------
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
51.76
32%
-84
- C1 -
3OAB
4
?
D:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
AVQ
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
GELAV
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
S
S
K
E
L
G
K
T
A
G
K
D
L
V
A
D
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
51.72
32%
-99
- C1 -
3KRO
4
?
A:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
A
V
Q
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
G
E
L
A
V
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
----------------
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.91
32%
-100
- C1 -
3KRC
1
?
A:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
A
V
Q
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
G
E
L
A
V
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
----------------
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
50.81
32%
-84
- C1 -
3KRO
4
?
D:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
AVQ
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
GELAV
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
S
S
K
E
L
G
K
T
A
G
K
D
L
V
A
D
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
50.78
32%
-90
- C1 -
3OYR
4
?
B:
[57-297]
--------------------------------------------------------------
A
E
H
L
I
A
A
G
--
G
K
R
L
R
P
L
M
T
V
A
A
A
R
L
A
G
A
D
-
N
D
H
F
Q
K
L
A
-----
A
A
---
V
E
F
I
H
T
A
T
L
L
H
D
D
V
--
V
D
G
S
Q
L
--
R
R
G
K
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
--------
D
F
L
F
A
R
A
F
-
E
L
M
--
V
------
E
T
N
----
S
-----
M
K
A
L
E
I
-
L
-----
A
--
R
--------
A
----
S
--
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
-
H
D
------------
L
N
L
S
--
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
-
A
A
A
S
E
A
G
A
V
S
A
-
G
V
D
V
-
A
K
S
E
A
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
G
G
A
T
E
T
L
G
K
N
A
G
D
D
F
R
E
G
K
A
T
L
P
-
L
L
L
-
A
I
A
R
S
G
P
R
-
E
-
A
E
-
F
W
E
R
A
I
G
R
R
------
E
------
Q
T
--
E
A
D
F
R
R
A
R
E
L
I
---------------------------------------------------------------------------
9
PsiBlast_PDB
50.50
32%
-97
- C1 -
3OAB
4
?
A:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
A
V
Q
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
G
E
L
A
V
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
----------------
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
50.28
32%
-84
- C1 -
3OAC
4
?
D:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
AVQ
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
GELAV
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
S
S
K
E
L
G
K
T
A
G
K
D
L
V
A
D
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
50.26
32%
-85
- C1 -
3KRF
4
?
D:
[3-264]
-----------------
D
F
D
G
Y
M
L
R
K
A
K
S
-----
V
N
K
A
L
E
A
AVQ
M
-
K
E
P
L
K
I
-------
H
E
S
M
R
Y
S
L
L
A
G
--
G
K
R
V
R
P
M
L
C
I
A
A
C
E
L
V
G
G
D
-
E
S
T
A
M
P
A
A
-----
C
A
---
V
E
M
I
H
T
M
S
L
M
H
D
D
L
PC
M
D
N
D
D
L
--
R
R
G
K
P
T
N
H
M
A
F
G
E
S
V
A
V
L
A
G
--------
D
A
L
L
S
F
A
F
-
E
H
V
--
A
A
A
T
K
--
G
A
P
----
P
-----
E
R
I
V
R
V
-
L
GELAV
S
--
I
--------
G
----
S
--
E
G
L
V
A
G
Q
V
V
D
V
C
S
E
-
G
M
------------
A
E
V
G
--
L
D
H
L
E
F
I
H
H
H
K
T
A
A
L
L
-
Q
G
S
V
V
L
G
A
I
L
G
-
G
G
K
E
-
E
E
V
A
K
L
R
K
F
A
N
C
I
G
L
L
F
Q
V
V
D
D
I
L
D
V
T
K
S
S
K
E
L
G
K
T
A
G
K
D
L
V
A
D
K
T
T
Y
P
-
K
L
I
-
G
V
E
K
S
K
E
F
-
A
-
D
R
-
L
---------------------------------------------------------------------------------------------------------------
65
HHSearch
46.91
33%
-92
- C1 -
1RQJ
5
ISPA_ECOLI
A:
[2-261]
------------------
D
F
P
Q
Q
L
E
A
C
V
K
Q
A
N
Q
A
L
S
R
F
I
A
P
LPF
Q
-
N
T
P
V
V
E
T
M
Q
Y
G
A
-----------
L
L
G
G
K
R
L
R
P
F
L
V
Y
A
T
G
H
M
F
G
V
S
-
T
N
T
L
D
A
P
A
-----
A
A
---
V
E
C
I
H
A
Y
S
L
I
H
D
D
L
PA
M
D
D
D
D
L
--
R
R
G
L
P
T
C
H
V
K
F
G
E
A
N
A
I
L
A
G
--------
D
A
L
Q
T
L
A
F
-
S
I
L
--
S
D
A
D
M
--
P
E
V
S
D
R
D
R
-----
I
S
M
I
S
E
-
L
-----
A
--
S
A
S
------
G
----
I
--
A
G
M
C
G
G
Q
A
L
D
L
D
A
E
-
G
K
-------------
H
V
P
--
L
D
A
L
E
R
I
H
R
H
K
T
G
A
L
I
-
R
A
A
V
R
L
G
A
L
S
A
-
G
D
K
G
R
R
A
L
P
V
L
D
K
Y
A
E
S
I
G
L
A
F
Q
V
Q
D
D
I
L
D
V
V
G
D
T
A
T
L
G
K
R
Q
G
A
D
Q
Q
L
G
K
S
T
Y
P
-
A
L
L
-
G
L
E
Q
A
R
K
-----------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
45.77
32%
-113
- C1 -
3OYR
1
?
A:
[57-297]
--------------------------------------------------------------
A
E
H
L
I
A
A
G
--
G
K
R
L
R
P
L
M
T
V
A
A
A
R
L
A
G
A
D
-
N
D
H
F
Q
K
L
A
-----
A
A
---
V
E
F
I
H
T
A
T
L
L
H
D
D
V
--
V
-----------
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
--------
D
F
L
F
A
R
A
F
-
E
L
M
--
V
------
E
T
N
----
S
-----
M
K
A
L
E
I
-
L
-----
A
--
R
--------
A
----
S
--
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
-
H
D
------------
L
N
L
S
--
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
-
A
A
A
S
E
A
G
A
V
S
A
-
G
V
D
V
-
A
K
S
E
A
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
-------------------
A
T
L
P
-
L
L
L
-
A
I
A
R
S
G
P
R
-
E
-
A
E
-
F
W
E
R
A
I
G
----------------
T
--
E
A
D
F
R
R
A
R
E
L
I
---------------------------------------------------------------------------
27
PsiBlast_CBE
41.55
36%
-86
- C1 -
4LLT
5
?
B:
[58-273]
--------------------------------------------------------------------
A
T
S
G
G
K
R
L
R
G
F
L
V
L
E
T
A
R
L
H
D
I
A
-
A
G
E
A
I
W
S
A
-----
T
A
---
I
E
A
L
H
A
Y
S
L
V
H
D
D
L
PC
M
D
N
D
D
M
--
R
R
G
Q
P
T
V
H
K
K
W
D
D
A
T
A
V
L
A
G
--------
D
A
L
Q
T
L
A
F
-
E
L
V
--
T
H
P
G
A
--
S
A
S
----
A
E
----
V
R
A
D
L
A
-
L
-----
S
--
L
--------
A
R
A
S
G
A
--
Q
G
M
V
L
G
Q
A
L
D
I
A
A
E
T
A
R
------------
A
P
L
S
--
L
D
E
I
T
R
L
Q
Q
G
K
T
G
A
L
I
-
G
W
S
A
Q
A
G
A
R
L
A
-
Q
A
D
----
T
A
A
L
K
R
Y
A
Q
A
L
G
L
A
F
Q
I
A
D
D
I
L
D
V
T
G
D
S
A
Q
V
G
K
A
V
G
K
D
A
S
A
G
K
A
T
F
V
-
S
L
L
-
G
L
D
A
--------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
41.28
36%
-86
- C1 -
4LLT
5
?
A:
[58-273]
--------------------------------------------------------------------
A
T
S
G
G
K
R
L
R
G
F
L
V
L
E
T
A
R
L
H
D
I
A
-
A
G
E
A
I
W
S
A
-----
T
A
---
I
E
A
L
H
A
Y
S
L
V
H
D
D
L
PC
M
D
N
D
D
M
--
R
R
G
Q
P
T
V
H
K
K
W
D
D
A
T
A
V
L
A
G
--------
D
A
L
Q
T
L
A
F
-
E
L
V
--
T
H
P
G
A
--
S
A
S
----
A
E
----
V
R
A
D
L
A
-
L
-----
S
--
L
--------
A
R
A
S
G
A
--
Q
G
M
V
L
G
Q
A
L
D
I
A
A
E
T
A
R
------------
A
P
L
S
--
L
D
E
I
T
R
L
Q
Q
G
K
T
G
A
L
I
-
G
W
S
A
Q
A
G
A
R
L
A
-
Q
A
D
----
T
A
A
L
K
R
Y
A
Q
A
L
G
L
A
F
Q
I
A
D
D
I
L
D
V
T
G
D
S
A
Q
V
G
K
A
V
G
K
D
A
S
A
G
K
A
T
F
V
-
S
L
L
-
G
L
D
A
--------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
41.14
36%
-85
- C1 -
4LLS
6
?
B:
[58-273]
--------------------------------------------------------------------
A
T
S
G
G
K
R
L
R
G
F
L
V
L
E
T
A
R
L
H
D
I
A
-
A
G
E
A
I
W
S
A
-----
T
A
---
I
E
A
L
H
A
Y
S
L
V
H
D
D
L
PC
M
D
N
D
D
M
--
R
R
G
Q
P
T
V
H
K
K
W
D
D
A
T
A
V
L
A
G
--------
D
A
L
Q
T
L
A
F
-
E
L
V
--
T
H
P
G
A
--
S
A
S
----
A
E
----
V
R
A
D
L
A
-
L
-----
S
--
L
--------
A
R
A
S
G
A
--
Q
G
M
V
L
G
Q
A
L
D
I
A
A
E
T
A
R
------------
A
P
L
S
--
L
D
E
I
T
R
L
Q
Q
G
K
T
G
A
L
I
-
G
W
S
A
Q
A
G
A
R
L
A
-
Q
A
D
----
T
A
A
L
K
R
Y
A
Q
A
L
G
L
A
F
Q
I
A
D
D
I
L
D
V
T
G
D
S
A
Q
V
G
K
A
V
G
K
D
A
S
A
G
K
A
T
F
V
-
S
L
L
-
G
L
D
A
--------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
40.63
36%
-84
- C1 -
4LLS
6
?
A:
[58-273]
--------------------------------------------------------------------
A
T
S
G
G
K
R
L
R
G
F
L
V
L
E
T
A
R
L
H
D
I
A
-
A
G
E
A
I
W
S
A
-----
T
A
---
I
E
A
L
H
A
Y
S
L
V
H
D
D
L
PC
M
D
N
D
D
M
--
R
R
G
Q
P
T
V
H
K
K
W
D
D
A
T
A
V
L
A
G
--------
D
A
L
Q
T
L
A
F
-
E
L
V
--
T
H
P
G
A
--
S
A
S
----
A
E
----
V
R
A
D
L
A
-
L
-----
S
--
L
--------
A
R
A
S
G
A
--
Q
G
M
V
L
G
Q
A
L
D
I
A
A
E
T
A
R
------------
A
P
L
S
--
L
D
E
I
T
R
L
Q
Q
G
K
T
G
A
L
I
-
G
W
S
A
Q
A
G
A
R
L
A
-
Q
A
D
----
T
A
A
L
K
R
Y
A
Q
A
L
G
L
A
F
Q
I
A
D
D
I
L
D
V
T
G
D
S
A
Q
V
G
K
A
V
G
K
D
A
S
A
G
K
A
T
F
V
-
S
L
L
-
G
L
D
A
--------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
39.95
33%
-85
- C1 -
1RQJ
5
ISPA_ECOLI
A:
[44-266]
------------------------------------------------------------------------
G
K
R
L
R
P
F
L
V
Y
A
T
G
H
M
F
G
V
S
-
T
N
T
L
D
A
P
A
-----
A
A
---
V
E
C
I
H
A
Y
S
L
I
H
D
D
L
--
P
A
M
D
D
D
DL
R
R
G
L
P
T
C
H
V
K
F
G
E
A
N
A
I
L
A
G
--------
D
A
L
Q
T
L
A
F
-
S
I
L
--
S
D
A
D
M
--
P
E
V
----
S
-----
D
R
--
D
R
-
I
-----
S
--
M
I
S
E
L
A
S
A
S
G
----
I
--
A
G
M
C
G
G
Q
A
L
D
L
D
A
E
-
G
K
-------------
H
V
P
--
L
D
A
L
E
R
I
H
R
H
K
T
G
A
L
I
-
R
A
A
V
R
L
G
A
L
S
A
G
D
K
G
R
-
R
A
L
P
V
L
D
K
Y
A
E
S
I
G
L
A
F
Q
V
Q
D
D
I
L
D
V
V
G
D
T
A
T
L
G
K
R
Q
G
A
D
Q
Q
L
G
K
S
T
Y
P
-
A
L
L
-
G
L
E
Q
A
R
K
K
-
A
-
R
D
-
L
---------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
39.79
33%
-87
- C1 -
1RQJ
5
ISPA_ECOLI
B:
[44-266]
------------------------------------------------------------------------
G
K
R
L
R
P
F
L
V
Y
A
T
G
H
M
F
G
V
S
-
T
N
T
L
D
A
P
A
-----
A
A
---
V
E
C
I
H
A
Y
S
L
I
H
D
D
L
--
P
A
M
D
D
D
DL
R
R
G
L
P
T
C
H
V
K
F
G
E
A
N
A
I
L
A
G
--------
D
A
L
Q
T
L
A
F
-
S
I
L
--
S
D
A
D
M
--
P
E
V
----
S
-----
D
R
--
D
R
-
I
-----
S
--
M
I
S
E
L
A
S
A
S
G
----
I
--
A
G
M
C
G
G
Q
A
L
D
L
D
A
E
-
G
K
-------------
H
V
P
--
L
D
A
L
E
R
I
H
R
H
K
T
G
A
L
I
-
R
A
A
V
R
L
G
A
L
S
A
G
D
K
G
R
-
R
A
L
P
V
L
D
K
Y
A
E
S
I
G
L
A
F
Q
V
Q
D
D
I
L
D
V
V
G
D
T
A
T
L
G
K
R
Q
G
A
D
Q
Q
L
G
K
S
T
Y
P
-
A
L
L
-
G
L
E
Q
A
R
K
K
-
A
-
R
D
-
L
---------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
39.55
33%
-84
- C1 -
1RQI
5
ISPA_ECOLI
B:
[45-267]
------------------------------------------------------------------------
G
K
R
L
R
P
F
L
V
Y
A
T
G
H
M
F
G
V
S
-
T
N
T
L
D
A
P
A
-----
A
A
---
V
E
C
I
H
A
Y
S
L
I
H
D
D
L
--
P
A
M
D
D
D
DL
R
R
G
L
P
T
C
H
V
K
F
G
E
A
N
A
I
L
A
G
--------
D
A
L
Q
T
L
A
F
-
S
I
L
--
S
D
A
D
M
--
P
E
V
----
S
-----
D
R
--
D
R
-
I
-----
S
--
M
I
S
E
L
A
S
A
S
G
----
I
--
A
G
M
C
G
G
Q
A
L
D
L
D
A
E
-
G
K
-------------
H
V
P
--
L
D
A
L
E
R
I
H
R
H
K
T
G
A
L
I
-
R
A
A
V
R
L
G
A
L
S
A
G
D
K
G
R
-
R
A
L
P
V
L
D
K
Y
A
E
S
I
G
L
A
F
Q
V
Q
D
D
I
L
D
V
V
G
D
T
A
T
L
G
K
R
Q
G
A
D
Q
Q
L
G
K
S
T
Y
P
-
A
L
L
-
G
L
E
Q
A
R
K
K
-
A
-
R
D
-
L
---------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
39.29
33%
-85
- C1 -
1RQI
6
ISPA_ECOLI
A:
[45-267]
------------------------------------------------------------------------
G
K
R
L
R
P
F
L
V
Y
A
T
G
H
M
F
G
V
S
-
T
N
T
L
D
A
P
A
-----
A
A
---
V
E
C
I
H
A
Y
S
L
I
H
D
D
L
--
P
A
M
D
D
D
DL
R
R
G
L
P
T
C
H
V
K
F
G
E
A
N
A
I
L
A
G
--------
D
A
L
Q
T
L
A
F
-
S
I
L
--
S
D
A
D
M
--
P
E
V
----
S
-----
D
R
--
D
R
-
I
-----
S
--
M
I
S
E
L
A
S
A
S
G
----
I
--
A
G
M
C
G
G
Q
A
L
D
L
D
A
E
-
G
K
-------------
H
V
P
--
L
D
A
L
E
R
I
H
R
H
K
T
G
A
L
I
-
R
A
A
V
R
L
G
A
L
S
A
G
D
K
G
R
-
R
A
L
P
V
L
D
K
Y
A
E
S
I
G
L
A
F
Q
V
Q
D
D
I
L
D
V
V
G
D
T
A
T
L
G
K
R
Q
G
A
D
Q
Q
L
G
K
S
T
Y
P
-
A
L
L
-
G
L
E
Q
A
R
K
K
-
A
-
R
D
-
L
---------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
36.78
31%
-80
- C1 -
4LFG
5
?
B:
[65-279]
---------------------------------------------------------------------------------------------------
A
-----
A
A
---
L
E
M
I
H
T
G
S
L
I
H
D
D
L
PA
M
D
N
D
D
Y
--
R
R
G
Q
L
T
N
H
K
K
F
D
E
A
T
A
I
L
A
G
--------
D
S
L
F
L
D
A
F
-
G
M
L
--
A
E
-
T
D
FP
T
D
V
----
T
-----
V
D
L
V
R
S
-
L
-----
S
--
S
--------
A
----
S
GT
F
G
M
V
G
G
Q
M
L
D
M
A
A
E
-
G
K
-------------
K
L
N
--
L
K
N
L
Q
L
I
H
R
H
K
T
G
Q
L
L
-
A
Y
P
F
W
A
A
A
R
V
A
-
Q
L
D
E
-
N
L
L
A
T
F
L
E
I
G
M
I
I
G
L
A
F
Q
V
R
D
D
I
L
D
I
T
A
N
F
E
E
I
G
K
T
P
K
K
D
V
M
A
E
K
M
T
Y
P
-
H
L
L
-
G
L
N
E
S
Y
Q
I
-
L
-
D
E
---
S
L
D
Q
A
E
A
------
I
------
L
R
--
K
L
S
D
E
I
A
F
A
P
Q
K
I
-------------------------------------------------------------------------
39
PsiBlast_CBE
36.22
31%
-78
- C1 -
4LFG
5
?
A:
[65-279]
---------------------------------------------------------------------------------------------------
A
-----
A
A
---
L
E
M
I
H
T
G
S
L
I
H
D
D
L
PA
M
D
N
D
D
Y
--
R
R
G
Q
L
T
N
H
K
K
F
D
E
A
T
A
I
L
A
G
--------
D
S
L
F
L
D
A
F
-
G
M
L
--
A
E
-
T
D
FP
T
D
V
----
T
-----
V
D
L
V
R
S
-
L
-----
S
--
S
--------
A
----
S
GT
F
G
M
V
G
G
Q
M
L
D
M
A
A
E
-
G
K
-------------
K
L
N
--
L
K
N
L
Q
L
I
H
R
H
K
T
G
Q
L
L
-
A
Y
P
F
W
A
A
A
R
V
A
-
Q
L
D
E
-
N
L
L
A
T
F
L
E
I
G
M
I
I
G
L
A
F
Q
V
R
D
D
I
L
D
I
T
A
N
F
E
E
I
G
K
T
P
K
K
D
V
M
A
E
K
M
T
Y
P
-
H
L
L
-
G
L
N
E
S
Y
Q
I
-
L
-
D
E
---
S
L
D
Q
A
E
A
------
I
------
L
R
--
K
L
S
D
E
I
A
F
A
P
Q
K
I
-------------------------------------------------------------------------
40
PsiBlast_CBE
35.99
31%
-79
- C1 -
4LFE
5
?
B:
[65-279]
---------------------------------------------------------------------------------------------------
A
-----
A
A
---
L
E
M
I
H
T
G
S
L
I
H
D
D
L
PA
M
D
N
D
D
Y
--
R
R
G
Q
L
T
N
H
K
K
F
D
E
A
T
A
I
L
A
G
--------
D
S
L
F
L
D
A
F
-
G
M
L
--
A
E
-
T
D
FP
T
D
V
----
T
-----
V
D
L
V
R
S
-
L
-----
S
--
S
--------
A
----
S
GT
F
G
M
V
G
G
Q
M
L
D
M
A
A
E
-
G
K
-------------
K
L
N
--
L
K
N
L
Q
L
I
H
R
H
K
T
G
Q
L
L
-
A
Y
P
F
W
A
A
A
R
V
A
-
Q
L
D
E
-
N
L
L
A
T
F
L
E
I
G
M
I
I
G
L
A
F
Q
V
R
D
D
I
L
D
I
T
A
N
F
E
E
I
G
K
T
P
K
K
D
V
M
A
E
K
M
T
Y
P
-
H
L
L
-
G
L
N
E
S
Y
Q
I
-
L
-
D
E
---
S
L
D
Q
A
E
A
------
I
------
L
R
--
K
L
S
D
E
I
A
F
A
P
Q
K
I
-------------------------------------------------------------------------
41
PsiBlast_CBE
35.97
31%
-91
- C1 -
4LFE
3
?
A:
[65-279]
---------------------------------------------------------------------------------------------------
A
-----
A
A
---
L
E
M
I
H
T
G
S
L
I
H
D
D
L
PA
M
D
N
D
D
Y
--
R
R
G
Q
L
T
N
H
K
K
F
D
E
A
T
A
I
L
A
G
--------
D
S
L
F
L
D
A
F
-
G
M
L
--
A
E
-
T
D
FP
T
D
V
----
T
-----
V
D
L
V
R
S
-
L
-----
S
--
S
--------
A
----
S
GT
F
G
M
V
G
G
Q
M
L
D
M
A
A
E
-
G
K
-------------
K
L
N
--
L
K
N
L
Q
L
I
H
R
H
K
T
G
Q
L
L
-
A
Y
P
F
W
A
A
A
R
V
A
-
Q
L
D
E
-
N
L
L
A
T
F
L
E
I
G
M
I
I
G
L
A
F
Q
V
R
D
D
I
L
D
I
T
A
----------------
K
M
T
Y
P
-
H
L
L
-
G
L
N
E
S
Y
Q
I
-
L
-
D
E
---
S
L
D
Q
A
E
A
------
I
------
L
R
--
K
L
S
D
E
I
A
F
A
P
Q
K
I
-------------------------------------------------------------------------