@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1301: (2016-03-24 )
MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
Atome Classification :
(68 SA)
--.........10........20........30........-40........50........60........70........80........90........100.....---..110.......120.......130.......140.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--M
E
R
T
F
L
M
IK
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
RK
G
L
K
L
VGG
K
L
M
Q
-
V
P
M
E
L
A
E
T
HYGEHQGK
P
F
Y
N
D
L
I
S
F
ITSA
P
V
F
A
M
V
VEGEDA
V
N
V
S
R
H
IIGSTNPSEASPGSIRGDL
G
L
---
T
VGRNIIHGSD
S
L
E
S
A
E
R
E
I
N
L
W
FNE
N
E
ITSYASPRDAWLYE
22
PsiBlast_CBE
98.14
100%
-113
- C8 -
3Q8Y
2
NDK_STAAC
G:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
28
PsiBlast_CBE
97.42
100%
-116
- C8 -
3Q8V
2
NDK_STAAC
D:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
25
PsiBlast_CBE
97.26
100%
-112
- C8 -
3Q8Y
3
NDK_STAAC
D:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
23
PsiBlast_CBE
97.01
100%
-113
- C8 -
3Q8Y
1
NDK_STAAC
F:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
29
PsiBlast_CBE
96.98
100%
-115
- C8 -
3Q8V
2
NDK_STAAC
B:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
37
PsiBlast_CBE
96.86
100%
-114
- C8 -
3Q86
1
NDK_STAAC
B:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
35
PsiBlast_CBE
96.72
100%
-112
- C8 -
3Q89
2
NDK_STAAC
E:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
31
PsiBlast_CBE
96.72
100%
-111
- C8 -
3Q8U
2
NDK_STAAC
E:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
27
PsiBlast_CBE
96.59
100%
-114
- C8 -
3Q8Y
2
NDK_STAAC
B:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
32
PsiBlast_CBE
96.39
100%
-112
- C8 -
3Q8U
2
NDK_STAAC
D:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
6
PsiBlast_PDB
96.33
100%
-112
- C8 -
3Q8Y
2
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
36
PsiBlast_CBE
96.26
100%
-113
- C8 -
3Q89
2
NDK_STAAC
B:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
26
PsiBlast_CBE
96.22
100%
-110
- C8 -
3Q8Y
1
NDK_STAAC
C:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
33
PsiBlast_CBE
96.20
100%
-111
- C8 -
3Q8U
1
NDK_STAAC
C:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
5
PsiBlast_PDB
96.12
100%
-112
- C8 -
3Q8V
2
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
3
PsiBlast_PDB
96.12
100%
-113
- C8 -
3Q89
-
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
1
PsiBlast_PDB
95.81
100%
-112
- C8 -
3Q83
-
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
21
PsiBlast_CBE
95.38
100%
-112
- C8 -
3Q8Y
3
NDK_STAAC
H:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
24
PsiBlast_CBE
95.29
100%
-113
- C8 -
3Q8Y
2
NDK_STAAC
E:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
102
HHSearch
95.15
100%
-109
- C8 -
3Q8U
3
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
4
PsiBlast_PDB
95.15
100%
-109
- C8 -
3Q8U
3
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
30
PsiBlast_CBE
95.08
100%
-110
- C8 -
3Q8U
2
NDK_STAAC
F:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
2
PsiBlast_PDB
94.83
100%
-110
- C8 -
3Q86
2
NDK_STAAC
A:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
34
PsiBlast_CBE
94.55
100%
-106
- C8 -
3Q8U
2
NDK_STAAC
B:
[1-149]
--
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
-
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
N
E
I
T
S
Y
A
S
P
R
D
A
W
L
Y
E
121
HHSearch
82.64
56%
-109
- C8 -
2DXE
3
NDK_PYRHO
A:
[7-156]
--
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
-
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
K
D
A
A
P
G
T
I
R
G
D
F
G
L
EVS
D
A
I
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
E
E
L
F
E
Y
P
R
A
A
D
-
W
F
Y
-
50
PsiBlast_CBE
80.62
54%
-105
- C8 -
1ZS6
1
NDK3_HUMAN
B:
[22-169]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
C
W
E
D
S
A
G
H
W
L
Y
E
49
PsiBlast_CBE
79.80
54%
-103
- C8 -
1ZS6
1
NDK3_HUMAN
D:
[22-169]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
C
W
E
D
S
A
G
H
W
L
Y
E
68
PsiBlast_CBE
79.24
56%
-100
- C8 -
1HIY
1
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
19
PsiBlast_PDB
79.20
56%
-99
- C8 -
2BEF
2
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
85
PsiBlast_CBE
79.04
51%
-103
- C8 -
2HVD
1
NDKA_HUMAN
A:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
51
PsiBlast_CBE
78.87
51%
-105
- C8 -
1S59
2
NDK2_ARATH
C:
[5-153]
--
V
E
E
T
Y
I
M
V
K
P
D
G
I
Q
R
G
L
V
G
E
I
I
S
R
F
E
K
K
G
F
K
L
I
G
L
K
M
F
Q
-
C
P
K
E
L
A
E
E
H
Y
K
D
L
S
A
K
S
F
F
P
N
L
I
E
Y
I
T
S
G
P
V
V
C
M
A
W
E
G
V
G
V
V
A
S
A
R
K
L
I
G
K
T
D
P
L
Q
A
E
P
G
T
I
R
G
D
L
A
V
---
Q
T
G
R
N
I
V
H
G
S
D
S
P
E
N
G
K
R
E
I
G
L
W
F
K
E
G
E
L
C
K
W
D
S
A
L
A
T
W
L
R
E
88
PsiBlast_CBE
78.69
51%
-107
- C8 -
2HVE
1
NDKA_HUMAN
C:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
14
PsiBlast_PDB
78.65
54%
-105
- C8 -
1ZS6
2
NDK3_HUMAN
A:
[22-169]
---
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
C
W
E
D
S
A
G
H
W
L
Y
E
64
PsiBlast_CBE
78.64
56%
-99
- C8 -
1NDC
2
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
66
PsiBlast_CBE
78.60
56%
-101
- C8 -
1KDN
2
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
105
HHSearch
78.51
54%
-104
- C8 -
1ZS6
2
NDK3_HUMAN
A:
[21-169]
--
H
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
-
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
D
E
L
L
C
W
E
D
S
A
G
H
W
L
Y
E
78
PsiBlast_CBE
78.48
56%
-99
- C8 -
1B99
1
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
59
PsiBlast_CBE
78.24
56%
-99
- C8 -
2BEF
2
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
70
PsiBlast_CBE
78.16
56%
-99
- C8 -
1F6T
2
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
18
PsiBlast_PDB
78.09
56%
-100
- C8 -
1KDN
2
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
77
PsiBlast_CBE
78.03
56%
-103
- C8 -
1B99
1
NDKC_DICDI
D:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
58
PsiBlast_CBE
77.76
56%
-100
- C8 -
2BEF
3
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
16
PsiBlast_PDB
77.70
51%
-98
- C8 -
1S59
1
NDK2_ARATH
A:
[5-153]
--
V
E
E
T
Y
I
M
V
K
P
D
G
I
Q
R
G
L
V
G
E
I
I
S
R
F
E
K
K
G
F
K
L
I
G
L
K
M
F
Q
-
C
P
K
E
L
A
E
E
H
Y
K
D
L
S
A
K
S
F
F
P
N
L
I
E
Y
I
T
S
G
P
V
V
C
M
A
W
E
G
V
G
V
V
A
S
A
R
K
L
I
G
K
T
D
P
L
Q
A
E
P
G
T
I
R
G
D
L
A
V
---
Q
T
G
R
N
I
V
H
G
S
D
S
P
E
N
G
K
R
E
I
G
L
W
F
K
E
G
E
L
C
K
W
D
S
A
L
A
T
W
L
R
E
90
PsiBlast_CBE
77.61
51%
-101
- C8 -
2HVE
2
NDKA_HUMAN
A:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
79
PsiBlast_CBE
77.60
56%
-97
- C8 -
1B99
1
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
93
PsiBlast_CBE
77.59
56%
-99
- C8 -
1LWX
1
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
83
PsiBlast_CBE
77.54
51%
-102
- C8 -
2HVD
1
NDKA_HUMAN
C:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
65
PsiBlast_CBE
77.52
56%
-96
- C8 -
1KDN
2
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
62
PsiBlast_CBE
77.45
56%
-104
- C8 -
1S5Z
1
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
20
PsiBlast_PDB
77.40
56%
-99
- C8 -
1BUX
1
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
73
PsiBlast_CBE
77.09
56%
-99
- C8 -
1BUX
1
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
67
PsiBlast_CBE
77.06
56%
-103
- C8 -
1HIY
1
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
63
PsiBlast_CBE
77.01
56%
-98
- C8 -
1NDP
1
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
75
PsiBlast_CBE
76.92
56%
-95
- C8 -
1B99
1
NDKC_DICDI
F:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
84
PsiBlast_CBE
76.78
51%
-98
- C8 -
2HVD
1
NDKA_HUMAN
B:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
80
PsiBlast_CBE
76.54
56%
-96
- C8 -
1B99
1
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
71
PsiBlast_CBE
76.49
56%
-96
- C8 -
1F6T
2
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
94
PsiBlast_CBE
76.48
56%
-101
- C8 -
1LWX
2
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
74
PsiBlast_CBE
76.44
56%
-101
- C8 -
1BUX
1
NDKC_DICDI
B:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
92
PsiBlast_CBE
75.92
56%
-99
- C8 -
1LWX
2
NDKC_DICDI
C:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
A
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
17
PsiBlast_PDB
75.86
56%
-93
- C8 -
1NDP
1
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
122
Fugue
75.76
56%
-92
- C8 -
1NDP
1
NDKC_DICDI
A:
[6-155]
VN
K
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
N
-
P
N
L
Y
E
72
PsiBlast_CBE
75.47
56%
-94
- C8 -
1F6T
3
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
89
PsiBlast_CBE
75.09
51%
-96
- C8 -
2HVE
1
NDKA_HUMAN
B:
[4-152]
--
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
-
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
E
76
PsiBlast_CBE
74.94
56%
-98
- C8 -
1B99
1
NDKC_DICDI
E:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
69
PsiBlast_CBE
74.31
56%
-93
- C8 -
1HIY
1
NDKC_DICDI
A:
[9-155]
---
E
R
T
F
L
A
V
K
P
D
G
V
A
R
G
L
V
G
E
I
I
A
R
Y
E
K
K
G
F
V
L
V
G
L
K
Q
L
V
-
P
T
K
D
L
A
E
S
H
Y
A
E
H
K
E
R
P
F
F
G
G
L
V
S
F
I
T
S
G
P
V
V
A
M
V
F
E
G
K
G
V
V
A
S
A
R
L
M
I
G
V
T
N
P
L
A
S
A
P
G
S
I
R
G
D
F
G
V
---
D
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
R
E
I
A
L
W
F
K
P
E
E
L
L
T
E
V
K
P
-
N
P
N
L
Y
E
120
HHSearch
74.16
43%
-111
- C8 -
3EVO
1
NDK_MIMIV
A:
[6-138]
--
L
Q
R
T
L
V
L
I
K
P
D
A
F
E
R
S
L
V
A
E
I
M
G
R
I
E
K
K
N
F
K
I
V
S
M
K
F
W
S
K
A
P
R
N
L
I
E
Q
H
Y
K
E
H
S
E
Q
S
Y
F
N
D
N
C
D
F
M
V
S
G
P
I
I
S
I
V
Y
E
G
T
D
A
I
S
K
I
R
R
L
Q
G
N
T
N
P
L
A
S
A
P
G
T
I
R
G
D
L
A
N
---
D
I
R
E
N
L
I
H
A
S
D
S
E
D
S
A
V
D
E
I
S
I
W
F
P
-----------------
117
HHSearch
72.86
47%
-103
- C8 -
1NHK
1
NDK_MYXXA
R:
[2-142]
--
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
-
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
A
Q
A
A
E
G
T
I
R
K
D
F
A
T
---
S
I
D
K
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
T
E
I
H
S
Y
P
Y
--------