@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0916: (2015-12-04 )
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIEVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
Atome Classification :
(68 SA)
---.........10........20........30........40........50........60........70........80........90..-......100.....---..110.......120.......130......----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---ME
Q
T
F
F
M
IKPDGVKR
G
F
I
G
E
V
I
S
R
I
E
R
RGFSI
D
R
L
E
V
RHA
D
A
D
I
L
K
R
H
Y
A
E
LTDRPF
F
P
T
L
V
D
Y
MTSG
P
V
I
I
E
VISG
E
E
V
I
S
T
W
R
T
M
MGSTNP-KDALPGTIRGDFAQ---APSPNQ
A
T
C
N
I
V
HGSDSPESA
T
R
E
I
A
I
W
FNN----------------
8
PsiBlast_PDB
93.18
50%
-112
- C7 -
3VVT
-
?
A:
[1-133]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
S
R
F
E
R
K
G
L
K
I
V
A
M
K
M
M
R
I
S
R
E
M
A
E
K
H
Y
A
E
H
R
E
K
P
F
F
S
A
L
V
D
Y
I
T
S
G
P
V
V
A
M
V
L
E
G
K
N
A
V
E
V
V
R
K
M
V
G
A
T
N
P
-
K
E
A
A
P
G
T
I
R
G
D
F
G
L
--------
D
V
G
K
N
V
I
H
A
S
D
S
P
E
S
A
E
R
E
I
S
L
F
F
K
D
----------------
105
HHSearch
92.94
53%
-111
- C7 -
1WKJ
-
NDK_THET8
A:
[1-133]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
L
P
G
T
I
R
G
D
F
A
T
---
T
-----
I
D
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
----------------
124
Fugue
91.94
54%
-104
- C7 -
1NDL
-
NDKA_DROME
A:
[2-153]
AAN
K
E
R
T
F
I
M
V
K
P
D
G
V
Q
R
G
L
V
G
K
I
I
E
R
F
E
Q
K
G
F
K
L
V
A
L
K
F
T
W
A
S
K
E
L
L
E
K
H
Y
A
D
L
S
A
R
P
F
F
P
G
L
V
N
Y
M
N
S
G
P
V
V
P
M
V
W
E
G
L
N
V
V
K
T
G
R
Q
M
L
G
A
T
N
P
-
A
D
S
L
P
G
T
I
R
G
D
F
C
I
---
Q
V
G
R
N
-----
I
I
H
G
S
D
A
V
E
S
A
E
K
E
I
A
L
W
F
N
E
KE
L
V
T
W
T
P
AAKDWIYE
29
PsiBlast_CBE
91.94
53%
-111
- C7 -
4ENO
1
NDKA_HUMAN
B:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
12
PsiBlast_PDB
91.31
53%
-109
- C7 -
4ENO
1
NDKA_HUMAN
A:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
26
PsiBlast_CBE
91.14
51%
-112
- C7 -
1WKL
2
NDK_THET8
B:
[1-132]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
L
P
G
T
I
R
G
D
F
A
--------
T
T
I
D
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
----------------
5
PsiBlast_PDB
90.94
51%
-109
- C7 -
1WKJ
-
NDK_THET8
A:
[1-132]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
L
P
G
T
I
R
G
D
F
A
--------
T
T
I
D
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
----------------
6
PsiBlast_PDB
90.68
51%
-107
- C7 -
1WKK
1
NDK_THET8
A:
[1-132]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
L
P
G
T
I
R
G
D
F
A
--------
T
T
I
D
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
----------------
23
PsiBlast_CBE
90.30
54%
-113
- C7 -
1BHN
1
NDKA1_BOVIN
D:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
1
PsiBlast_PDB
90.30
53%
-109
- C7 -
1NDL
-
NDKA_DROME
A:
[6-136]
----
E
R
T
F
I
M
V
K
P
D
G
V
Q
R
G
L
V
G
K
I
I
E
R
F
E
Q
K
G
F
K
L
V
A
L
K
F
T
W
A
S
K
E
L
L
E
K
H
Y
A
D
L
S
A
R
P
F
F
P
G
L
V
N
Y
M
N
S
G
P
V
V
P
M
V
W
E
G
L
N
V
V
K
T
G
R
Q
M
L
G
A
T
N
P
-
A
D
S
L
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
A
V
E
S
A
E
K
E
I
A
L
W
F
N
E
----------------
21
PsiBlast_CBE
90.24
54%
-114
- C7 -
1BHN
1
NDKA1_BOVIN
F:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
120
HHSearch
90.23
55%
-110
- C7 -
3L7U
-
NDKA_HUMAN
A:
[24-155]
---
C
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
-----
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
7
PsiBlast_PDB
90.16
51%
-111
- C7 -
1WKL
2
NDK_THET8
A:
[1-132]
---
M
E
R
T
F
V
M
I
K
P
D
G
V
R
R
G
L
V
G
E
I
L
A
R
F
E
R
K
G
F
R
I
A
A
L
K
L
M
Q
I
S
Q
E
L
A
E
R
H
Y
A
E
H
R
E
K
P
F
F
P
G
L
V
R
F
I
T
S
G
P
V
V
A
M
V
L
E
G
P
G
V
V
A
E
V
R
K
M
M
G
A
T
H
P
-
K
D
A
L
P
G
T
I
R
G
D
F
A
--------
T
T
I
D
E
N
V
I
H
G
S
A
T
L
E
D
A
Q
R
E
I
A
L
F
F
R
P
----------------
48
PsiBlast_CBE
89.78
51%
-109
- C7 -
1NUE
1
NDKB_HUMAN
C:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
108
HHSearch
89.77
53%
-109
- C7 -
1VYA
-
?
A:
[1-133]
---
M
E
S
T
F
I
M
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
F
Y
L
K
A
L
K
L
V
N
V
E
R
S
F
A
E
K
H
Y
A
D
L
A
S
K
P
F
F
Q
G
L
V
D
Y
I
I
S
G
P
V
V
A
M
V
W
E
G
K
S
V
V
T
T
G
R
K
I
I
G
A
T
N
P
-
L
A
S
E
P
G
T
I
R
G
D
F
A
V
---
D
-----
I
G
R
N
V
I
H
G
S
D
S
I
E
S
A
N
K
E
I
A
L
W
F
P
E
----------------
13
PsiBlast_PDB
89.68
54%
-109
- C7 -
1BE4
1
NDKA2_BOVIN
A:
[4-133]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
M
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
R
P
----------------
42
PsiBlast_CBE
89.58
51%
-108
- C7 -
3BBB
2
NDKB_HUMAN
E:
[4-134]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
24
PsiBlast_CBE
89.56
54%
-104
- C7 -
1BHN
1
NDKA1_BOVIN
C:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
115
HHSearch
89.54
53%
-103
- C7 -
3BBB
-
NDKB_HUMAN
A:
[3-135]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
---
Q
-----
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
22
PsiBlast_CBE
89.54
54%
-107
- C7 -
1BHN
1
NDKA1_BOVIN
E:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
34
PsiBlast_CBE
89.40
52%
-109
- C7 -
2HVE
1
NDKA_HUMAN
C:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
4
PsiBlast_PDB
89.37
54%
-109
- C7 -
1BHN
1
NDKA1_BOVIN
A:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
47
PsiBlast_CBE
89.28
51%
-104
- C7 -
1NUE
1
NDKB_HUMAN
D:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
114
HHSearch
89.08
48%
-113
- C7 -
3Q8U
2
NDK_STAAC
A:
[1-133]
---
M
E
R
T
F
L
M
I
K
P
D
A
V
Q
R
N
L
I
G
E
V
I
S
R
I
E
R
K
G
L
K
L
V
G
G
K
L
M
Q
V
P
M
E
L
A
E
T
H
Y
G
E
H
Q
G
K
P
F
Y
N
D
L
I
S
F
I
T
S
A
P
V
F
A
M
V
V
E
G
E
D
A
V
N
V
S
R
H
I
I
G
S
T
N
P
-
S
E
A
S
P
G
S
I
R
G
D
L
G
L
---
T
-----
V
G
R
N
I
I
H
G
S
D
S
L
E
S
A
E
R
E
I
N
L
W
F
N
E
----------------
45
PsiBlast_CBE
89.04
51%
-111
- C7 -
1NUE
1
NDKB_HUMAN
F:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
32
PsiBlast_CBE
88.88
54%
-104
- C7 -
1BE4
1
NDKA2_BOVIN
C:
[4-133]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
M
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
R
P
----------------
16
PsiBlast_PDB
88.85
51%
-110
- C7 -
1NUE
2
NDKB_HUMAN
A:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
43
PsiBlast_CBE
88.82
51%
-106
- C7 -
3BBB
2
NDKB_HUMAN
C:
[4-134]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
37
PsiBlast_CBE
88.76
51%
-108
- C7 -
3BBF
4
NDKB_HUMAN
E:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
36
PsiBlast_CBE
88.58
51%
-111
- C7 -
3BBF
3
NDKB_HUMAN
F:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
30
PsiBlast_CBE
88.38
53%
-104
- C7 -
2HVD
1
NDKA_HUMAN
C:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
25
PsiBlast_CBE
88.23
54%
-103
- C7 -
1BHN
1
NDKA1_BOVIN
B:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
H
P
----------------
62
PsiBlast_CBE
88.18
52%
-98
- C7 -
1UCN
3
NDKA_HUMAN
A:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
W
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
G
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
39
PsiBlast_CBE
88.18
51%
-104
- C7 -
3BBF
1
NDKB_HUMAN
C:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
41
PsiBlast_CBE
88.17
51%
-105
- C7 -
3BBB
1
NDKB_HUMAN
F:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
31
PsiBlast_CBE
88.06
53%
-100
- C7 -
2HVD
1
NDKA_HUMAN
B:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
38
PsiBlast_CBE
87.81
51%
-104
- C7 -
3BBF
2
NDKB_HUMAN
D:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
50
PsiBlast_CBE
87.63
50%
-104
- C7 -
4UOH
2
?
C:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
49
PsiBlast_CBE
87.63
51%
-105
- C7 -
1NUE
1
NDKB_HUMAN
B:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
61
PsiBlast_CBE
87.55
52%
-100
- C7 -
1UCN
4
NDKA_HUMAN
B:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
W
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
G
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
18
PsiBlast_PDB
87.54
51%
-107
- C7 -
3BBF
3
NDKB_HUMAN
A:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
33
PsiBlast_CBE
87.53
54%
-104
- C7 -
1BE4
1
NDKA2_BOVIN
B:
[4-133]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
M
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
M
R
A
S
E
D
L
L
K
E
H
Y
I
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
A
L
W
F
R
P
----------------
46
PsiBlast_CBE
87.14
51%
-105
- C7 -
1NUE
1
NDKB_HUMAN
E:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
40
PsiBlast_CBE
87.08
51%
-104
- C7 -
3BBF
2
NDKB_HUMAN
B:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
52
PsiBlast_CBE
87.03
50%
-105
- C7 -
4UOG
2
?
C:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
14
PsiBlast_PDB
86.97
52%
-104
- C7 -
2HVE
1
NDKA_HUMAN
A:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
35
PsiBlast_CBE
86.94
52%
-101
- C7 -
2HVE
1
NDKA_HUMAN
B:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
G
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
60
PsiBlast_CBE
86.93
52%
-98
- C7 -
1UCN
4
NDKA_HUMAN
C:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
W
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
G
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
55
PsiBlast_CBE
86.89
50%
-102
- C7 -
4UOF
2
?
C:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
123
HHSearch
86.86
47%
-104
- C7 -
2DXE
2
NDK_PYRHO
A:
[7-142]
---
T
E
R
T
L
V
I
I
K
P
D
A
V
V
R
G
L
I
G
E
I
I
S
R
F
E
K
K
G
L
K
I
V
G
M
K
M
I
W
I
D
R
E
L
A
E
K
H
Y
E
E
H
R
E
K
P
F
F
K
A
L
I
D
Y
I
T
K
T
P
V
V
V
M
V
L
E
G
R
Y
A
V
E
V
V
R
K
M
A
G
A
T
D
P
-
K
D
A
A
P
G
T
I
R
G
D
F
G
L
EVS
D
-----
A
I
C
N
V
I
H
A
S
D
S
K
E
S
A
E
R
E
I
S
L
F
F
K
P
----------------
101
PsiBlast_CBE
86.74
47%
-103
- C7 -
3NGS
1
?
B:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
A
R
F
E
R
K
G
Y
K
L
V
A
L
K
I
L
Q
P
T
T
E
Q
A
Q
G
H
Y
K
D
L
C
S
K
P
F
F
P
A
L
V
K
Y
F
S
S
G
P
I
V
C
M
V
W
E
G
K
N
V
V
K
S
G
R
V
L
L
G
A
T
N
P
-
A
D
S
Q
P
G
T
I
R
G
D
F
A
V
--------
D
V
G
R
N
V
C
H
G
S
D
S
V
E
S
A
E
R
E
I
A
F
W
F
K
A
----------------
11
PsiBlast_PDB
86.68
53%
-104
- C7 -
2HVD
1
NDKA_HUMAN
A:
[5-135]
----
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
W
F
H
P
----------------
44
PsiBlast_CBE
86.62
51%
-103
- C7 -
3BBB
1
NDKB_HUMAN
B:
[3-134]
---
L
E
R
T
F
I
A
I
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
K
R
F
E
Q
K
G
F
R
L
V
A
M
K
F
L
R
A
S
E
E
H
L
K
Q
H
Y
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
M
N
S
G
P
V
V
A
M
V
W
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
N
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
I
--------
Q
V
G
R
N
I
I
H
G
S
D
S
V
K
S
A
E
K
E
I
S
L
W
F
K
P
----------------
119
HHSearch
86.58
52%
-111
- C7 -
1ZS6
1
NDK3_HUMAN
A:
[21-153]
---
H
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
-
A
D
A
P
P
G
T
I
R
G
D
F
C
I
---
E
-----
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
----------------
51
PsiBlast_CBE
86.43
50%
-107
- C7 -
4UOH
2
?
B:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
20
PsiBlast_PDB
86.37
50%
-103
- C7 -
4UOF
2
?
A:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
57
PsiBlast_CBE
86.34
50%
-104
- C7 -
1ZS6
1
NDK3_HUMAN
D:
[22-152]
----
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
-
A
D
A
P
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
----------------
56
PsiBlast_CBE
86.33
50%
-100
- C7 -
4UOF
2
?
B:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
86
PsiBlast_CBE
86.29
47%
-100
- C7 -
3NGU
1
?
A:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
A
R
F
E
R
K
G
Y
K
L
V
A
L
K
I
L
Q
P
T
T
E
Q
A
Q
G
H
Y
K
D
L
C
S
K
P
F
F
P
A
L
V
K
Y
F
S
S
G
P
I
V
C
M
V
W
E
G
K
N
V
V
K
S
G
R
V
L
L
G
A
T
N
P
-
A
D
S
Q
P
G
T
I
R
G
D
F
A
V
--------
D
V
G
R
N
V
C
H
G
S
D
S
V
E
S
A
E
R
E
I
A
F
W
F
K
A
----------------
54
PsiBlast_CBE
86.28
50%
-105
- C7 -
4UOG
2
?
A:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
84
PsiBlast_CBE
86.20
49%
-107
- C7 -
4ANE
1
NDK_MYCTU
A:
[3-133]
----
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
G
K
P
F
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
--------
E
T
Q
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
----------------
59
PsiBlast_CBE
85.40
50%
-108
- C7 -
1ZS6
1
NDK3_HUMAN
A:
[22-152]
----
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
-
A
D
A
P
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
----------------
53
PsiBlast_CBE
85.31
50%
-100
- C7 -
4UOG
2
?
B:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
I
G
E
I
I
K
R
F
E
A
K
G
F
K
L
A
G
M
K
Y
I
Q
A
S
E
D
L
L
K
Q
H
Y
I
D
L
A
D
K
P
F
Y
P
G
L
C
K
Y
M
S
S
G
P
V
V
A
M
C
W
E
G
T
G
V
V
K
T
A
R
V
M
M
G
E
T
R
P
-
A
D
S
K
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
R
N
I
I
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
W
F
K
P
----------------
58
PsiBlast_CBE
85.24
50%
-103
- C7 -
1ZS6
1
NDK3_HUMAN
B:
[22-152]
----
E
R
T
F
L
A
V
K
P
D
G
V
Q
R
R
L
V
G
E
I
V
R
R
F
E
R
K
G
F
K
L
V
A
L
K
L
V
Q
A
S
E
E
L
L
R
E
H
Y
A
E
L
R
E
R
P
F
Y
G
R
L
V
K
Y
M
A
S
G
P
V
V
A
M
V
W
Q
G
L
D
V
V
R
T
S
R
A
L
I
G
A
T
N
P
-
A
D
A
P
P
G
T
I
R
G
D
F
C
--------
I
E
V
G
K
N
L
I
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
W
F
R
A
----------------
85
PsiBlast_CBE
84.97
47%
-106
- C7 -
3NGU
1
?
B:
[4-134]
----
E
R
T
F
I
A
V
K
P
D
G
V
Q
R
G
L
V
G
E
I
I
A
R
F
E
R
K
G
Y
K
L
V
A
L
K
I
L
Q
P
T
T
E
Q
A
Q
G
H
Y
K
D
L
C
S
K
P
F
F
P
A
L
V
K
Y
F
S
S
G
P
I
V
C
M
V
W
E
G
K
N
V
V
K
S
G
R
V
L
L
G
A
T
N
P
-
A
D
S
Q
P
G
T
I
R
G
D
F
A
V
--------
D
V
G
R
N
V
C
H
G
S
D
S
V
E
S
A
E
R
E
I
A
F
W
F
K
A
----------------
83
PsiBlast_CBE
84.53
49%
-105
- C7 -
4ANE
1
NDK_MYCTU
D:
[3-133]
----
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
V
S
A
E
L
A
S
Q
H
Y
A
E
H
E
----
F
G
S
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
--------
E
T
Q
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
----------------
82
PsiBlast_CBE
83.15
49%
-104
- C7 -
4ANE
1
NDK_MYCTU
F:
[3-133]
----
E
R
T
L
V
L
I
K
P
D
G
I
E
R
Q
L
I
G
E
I
I
S
R
I
E
R
K
G
L
T
I
A
A
L
Q
L
R
T
V
S
A
E
L
A
S
Q
H
Y
A
E
H
--------
L
L
E
F
I
T
S
G
P
V
V
A
A
I
V
E
G
T
N
A
I
A
A
V
R
Q
L
A
G
G
T
D
P
V
Q
A
A
A
P
G
T
I
R
G
D
F
A
L
--------
E
T
Q
F
N
L
V
H
G
S
D
S
A
E
S
A
Q
R
E
I
A
L
W
F
P
G
----------------
109
HHSearch
81.49
44%
-97
- C7 -
1NHK
1
NDK_MYXXA
R:
[2-134]
---
I
E
R
T
L
S
I
I
K
P
D
G
L
E
K
G
V
I
G
K
I
I
S
R
F
E
E
K
G
L
K
P
V
A
I
R
L
Q
H
L
S
Q
A
Q
A
E
G
F
Y
A
V
H
K
A
R
P
F
F
K
D
L
V
Q
F
M
I
S
G
P
V
V
L
M
V
L
E
G
E
N
A
V
L
A
N
R
D
I
M
G
A
T
N
P
-
A
Q
A
A
E
G
T
I
R
K
D
F
A
T
---
S
-----
I
D
K
N
T
V
H
G
S
D
S
L
E
N
A
K
I
E
I
A
Y
F
F
R
E
----------------