@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0236: (2016-03-13 )
MIRIGQGYDVHKLAYDRDLIIGGVKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMVFKDADSAELLAEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGREEGIASLAVVLLEK
Atome Classification :
(91 SA)
.........10.......--.20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MIRIGQGY
D
V
H
K
L
AYDR
D
--
L
I
IG
G
V
KIPYEKGLLGH
S
D
A
D
V
L
L
H
A
I
T
D
A
I
I
G
AIGAG
D
I
GHFFPDTD
M
V
FKDA
D
S
A
E
L
L
A
E
I
W
Q
K
VEADG
F
R
LGNL
D
A
T
I
I
AEKPKM
A
P
Y
V
E
Q
M
K
L
R
I
A
E
L
LHADS
A
Q
V
N
V
K
A
T
T
T
EKLGFT
G
R
E
E
G
I
A
S
L
A
V
V
LLEK
47
PsiBlast_CBE
98.06
62%
-119
- C10 -
3ERN
4
ISPF_ECOLI
E:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
51
PsiBlast_CBE
97.84
62%
-121
- C10 -
3ELC
4
ISPF_ECOLI
C:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
31
PsiBlast_CBE
97.56
62%
-120
- C10 -
1H48
8
ISPF_ECOLI
E:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
102
HHSearch
97.55
61%
-117
- C10 -
1T0A
4
ISPF_SHEON
A:
[2-158]
K
I
R
I
G
H
G
F
D
V
H
K
F
G
E
P
R
P
--
L
I
L
C
G
V
E
V
P
Y
E
T
G
L
V
A
H
S
D
G
D
V
V
L
H
A
I
S
D
A
I
L
G
A
M
A
L
G
D
I
G
K
H
F
P
D
T
D
A
A
Y
K
G
A
D
S
R
V
L
L
R
H
C
Y
A
L
A
K
A
K
G
F
E
L
G
N
L
D
V
T
I
I
A
Q
A
P
K
M
A
P
H
I
E
D
M
R
Q
V
L
A
A
D
L
N
A
D
V
A
D
I
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
K
E
G
I
A
V
E
A
V
V
L
L
S
R
34
PsiBlast_CBE
97.35
62%
-118
- C10 -
1H48
6
ISPF_ECOLI
B:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
90
PsiBlast_CBE
97.09
58%
-122
- C10 -
3JVH
4
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
96
PsiBlast_CBE
97.04
58%
-124
- C10 -
3IEQ
4
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
39
PsiBlast_CBE
96.98
62%
-121
- C10 -
1H47
5
ISPF_ECOLI
B:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
10
PsiBlast_PDB
96.92
62%
-120
- C10 -
1H48
6
ISPF_ECOLI
A:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
28
PsiBlast_CBE
96.88
62%
-116
- C10 -
3GHZ
4
ISPF_SALTY
C:
[4-159]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
20
PsiBlast_PDB
96.76
62%
-120
- C10 -
3ESJ
4
ISPF_ECOLI
A:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
32
PsiBlast_CBE
96.70
62%
-116
- C10 -
1H48
8
ISPF_ECOLI
D:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
93
PsiBlast_CBE
96.64
58%
-121
- C10 -
3IEW
4
ISPF_BURPS
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
87
PsiBlast_CBE
96.62
58%
-123
- C10 -
3K14
5
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
6
PsiBlast_PDB
96.62
62%
-117
- C10 -
3T80
10
ISPF_SALTY
A:
[4-159]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
4
PsiBlast_PDB
96.61
60%
-117
- C10 -
1T0A
4
ISPF_SHEON
A:
[3-158]
-
I
R
I
G
H
G
F
D
V
H
K
F
G
E
P
R
P
--
L
I
L
C
G
V
E
V
P
Y
E
T
G
L
V
A
H
S
D
G
D
V
V
L
H
A
I
S
D
A
I
L
G
A
M
A
L
G
D
I
G
K
H
F
P
D
T
D
A
A
Y
K
G
A
D
S
R
V
L
L
R
H
C
Y
A
L
A
K
A
K
G
F
E
L
G
N
L
D
V
T
I
I
A
Q
A
P
K
M
A
P
H
I
E
D
M
R
Q
V
L
A
A
D
L
N
A
D
V
A
D
I
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
K
E
G
I
A
V
E
A
V
V
L
L
S
R
5
PsiBlast_PDB
96.55
62%
-118
- C10 -
3GHZ
5
ISPF_SALTY
A:
[4-159]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
106
HHSearch
96.54
58%
-123
- C10 -
3F0D
1
ISPF_BURP1
A:
[23-179]
D
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
19
PsiBlast_PDB
96.45
62%
-120
- C10 -
3ERN
4
ISPF_ECOLI
A:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
9
PsiBlast_PDB
96.36
62%
-121
- C10 -
1H47
4
ISPF_ECOLI
A:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
48
PsiBlast_CBE
96.20
62%
-117
- C10 -
3ERN
4
ISPF_ECOLI
D:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
50
PsiBlast_CBE
96.18
62%
-119
- C10 -
3ERN
5
ISPF_ECOLI
B:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
43
PsiBlast_CBE
96.17
62%
-118
- C10 -
2AMT
5
ISPF_ECOLI
C:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
55
PsiBlast_CBE
96.16
58%
-114
- C10 -
4C8I
4
ISPF_BURCJ
B:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
A
A
F
K
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
36
PsiBlast_CBE
96.07
62%
-120
- C10 -
1H47
4
ISPF_ECOLI
E:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
72
PsiBlast_CBE
95.98
58%
-122
- C10 -
3P10
5
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
15
PsiBlast_PDB
95.97
62%
-118
- C10 -
1U43
1
ISPF_ECOLI
A:
[1-155]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-
33
PsiBlast_CBE
95.89
62%
-116
- C10 -
1H48
6
ISPF_ECOLI
C:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
37
PsiBlast_CBE
95.88
62%
-118
- C10 -
1H47
4
ISPF_ECOLI
D:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
78
PsiBlast_CBE
95.77
58%
-122
- C10 -
3MBM
5
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
66
PsiBlast_CBE
95.74
58%
-123
- C10 -
3QHD
6
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
52
PsiBlast_CBE
95.71
62%
-118
- C10 -
3ELC
4
ISPF_ECOLI
B:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
75
PsiBlast_CBE
95.70
58%
-123
- C10 -
3P0Z
5
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
30
PsiBlast_CBE
95.62
62%
-119
- C10 -
1H48
8
ISPF_ECOLI
F:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
84
PsiBlast_CBE
95.60
58%
-125
- C10 -
3K2X
5
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
16
PsiBlast_PDB
95.54
62%
-119
- C10 -
2AMT
4
ISPF_ECOLI
A:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
12
PsiBlast_PDB
95.44
62%
-123
- C10 -
1U3L
3
ISPF_ECOLI
A:
[1-155]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-
99
PsiBlast_CBE
95.41
58%
-116
- C10 -
3F0G
3
ISPF_BURP1
D:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
38
PsiBlast_CBE
95.41
62%
-119
- C10 -
1H47
4
ISPF_ECOLI
C:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
40
PsiBlast_CBE
95.32
62%
-115
- C10 -
2AMT
4
ISPF_ECOLI
F:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
17
PsiBlast_PDB
95.32
62%
-117
- C10 -
3ELC
4
ISPF_ECOLI
A:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
64
PsiBlast_CBE
95.14
58%
-119
- C10 -
3QHD
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
35
PsiBlast_CBE
95.05
62%
-116
- C10 -
1H47
4
ISPF_ECOLI
F:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
41
PsiBlast_CBE
95.00
62%
-120
- C10 -
2AMT
4
ISPF_ECOLI
E:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
14
PsiBlast_PDB
94.96
62%
-120
- C10 -
1U40
2
ISPF_ECOLI
A:
[1-155]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-
44
PsiBlast_CBE
94.91
62%
-118
- C10 -
2AMT
4
ISPF_ECOLI
B:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
62
PsiBlast_CBE
94.70
58%
-117
- C10 -
4C8E
6
ISPF_BURCJ
A:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
A
A
F
K
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
49
PsiBlast_CBE
94.60
62%
-122
- C10 -
3ERN
3
ISPF_ECOLI
C:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
------
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
8
PsiBlast_PDB
94.57
60%
-119
- C10 -
3FPI
5
ISPF_YERPE
A:
[5-159]
--
R
I
G
H
G
F
D
V
H
K
F
G
E
N
G
S
GP
L
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
A
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
G
L
L
R
E
A
Y
R
R
I
L
A
K
G
Y
K
L
G
N
L
D
I
T
I
I
A
Q
A
P
K
M
A
P
H
I
P
Q
M
R
V
N
L
A
E
D
L
Q
C
H
M
D
D
I
N
V
K
A
T
T
T
E
Q
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
V
L
L
--
71
PsiBlast_CBE
94.54
58%
-118
- C10 -
3P10
3
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
73
PsiBlast_CBE
94.43
58%
-125
- C10 -
3P0Z
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
103
HHSearch
94.42
61%
-117
- C10 -
1YQN
4
ISPF_ECOLI
A:
[2-158]
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
M
G
L
G
I
A
C
E
A
V
A
L
L
I
K
42
PsiBlast_CBE
94.35
62%
-113
- C10 -
2AMT
4
ISPF_ECOLI
D:
[1-156]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
26
PsiBlast_CBE
94.21
62%
-118
- C10 -
3T80
9
ISPF_SALTY
C:
[4-159]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
------
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
83
PsiBlast_CBE
94.19
58%
-123
- C10 -
3K2X
3
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
---
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
54
PsiBlast_CBE
94.14
58%
-116
- C10 -
4C8I
4
ISPF_BURCJ
C:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
-------
K
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
81
PsiBlast_CBE
94.10
58%
-126
- C10 -
3KE1
3
ISPF_BURP1
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
67
PsiBlast_CBE
94.10
58%
-119
- C10 -
3Q8H
3
ISPF_BURPS
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
88
PsiBlast_CBE
93.99
58%
-120
- C10 -
3JVH
4
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
89
PsiBlast_CBE
93.88
58%
-123
- C10 -
3JVH
4
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
92
PsiBlast_CBE
93.79
58%
-127
- C10 -
3IEW
4
ISPF_BURPS
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
-----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
70
PsiBlast_CBE
93.74
58%
-123
- C10 -
3P10
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
63
PsiBlast_CBE
93.70
60%
-117
- C10 -
1YQN
4
ISPF_ECOLI
A:
[3-158]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
M
G
L
G
I
A
C
E
A
V
A
L
L
I
K
80
PsiBlast_CBE
93.66
58%
-123
- C10 -
3KE1
3
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
60
PsiBlast_CBE
93.66
58%
-116
- C10 -
4C8E
7
ISPF_BURCJ
C:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
A
A
F
K
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
46
PsiBlast_CBE
93.57
62%
-127
- C10 -
3ERN
2
ISPF_ECOLI
F:
[7-162]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
---
P
--
I
I
I
G
G
V
R
I
P
Y
------
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
76
PsiBlast_CBE
93.52
58%
-119
- C10 -
3MBM
5
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
-------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
68
PsiBlast_CBE
93.52
58%
-121
- C10 -
3Q8H
3
ISPF_BURPS
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
59
PsiBlast_CBE
93.34
58%
-124
- C10 -
4C8G
4
ISPF_BURCJ
A:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
--------
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
77
PsiBlast_CBE
93.28
58%
-121
- C10 -
3MBM
5
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
-
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
---
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
58
PsiBlast_CBE
93.28
58%
-127
- C10 -
4C8G
5
ISPF_BURCJ
B:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
-------
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
101
PsiBlast_CBE
93.00
58%
-122
- C10 -
3F0G
3
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
--
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
--
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
57
PsiBlast_CBE
92.96
58%
-120
- C10 -
4C8G
4
ISPF_BURCJ
C:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
--------
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
61
PsiBlast_CBE
92.85
58%
-116
- C10 -
4C8E
7
ISPF_BURCJ
B:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
A
A
F
K
G
A
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
85
PsiBlast_CBE
92.67
58%
-122
- C10 -
3K14
4
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
86
PsiBlast_CBE
92.55
58%
-126
- C10 -
3K14
4
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
98
PsiBlast_CBE
92.12
58%
-119
- C10 -
3F0G
3
ISPF_BURP1
E:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
-----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
95
PsiBlast_CBE
92.05
58%
-122
- C10 -
3IEQ
4
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
--
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
82
PsiBlast_CBE
92.05
58%
-128
- C10 -
3K2X
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
97
PsiBlast_CBE
92.02
58%
-123
- C10 -
3F0G
3
ISPF_BURP1
F:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
56
PsiBlast_CBE
91.81
58%
-117
- C10 -
4C8I
4
ISPF_BURCJ
A:
[24-179]
-
V
R
I
G
Q
G
Y
D
V
H
Q
L
V
E
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
V
L
L
R
A
C
A
E
R
V
K
A
A
G
F
T
I
Q
N
V
D
S
T
V
I
A
Q
A
P
K
L
A
P
H
I
D
G
M
R
A
N
I
A
A
D
L
G
L
P
L
E
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
L
V
K
91
PsiBlast_CBE
91.59
58%
-121
- C10 -
3IEW
4
ISPF_BURPS
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
27
PsiBlast_CBE
91.55
62%
-118
- C10 -
3T80
12
ISPF_SALTY
B:
[4-159]
-
M
R
I
G
H
G
F
D
V
H
A
F
G
G
E
G
P
--
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
----------
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
94
PsiBlast_CBE
91.53
58%
-122
- C10 -
3IEQ
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
74
PsiBlast_CBE
91.51
58%
-122
- C10 -
3P0Z
4
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
--------
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
79
PsiBlast_CBE
91.07
58%
-124
- C10 -
3KE1
3
ISPF_BURP1
C:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
69
PsiBlast_CBE
89.44
58%
-128
- C10 -
3Q8H
5
ISPF_BURPS
A:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
110
HHSearch
88.51
50%
-117
- C10 -
1W55
3
ISPDF_CAMJE
A:
[210-365]
-
I
F
T
G
N
G
F
D
V
H
E
F
G
E
N
R
P
--
L
L
L
A
G
V
Q
I
H
P
T
M
G
L
K
A
H
S
D
G
D
V
L
A
H
S
L
T
D
A
I
L
G
A
A
G
L
G
D
I
G
E
L
Y
P
D
T
D
M
K
F
K
N
A
N
S
M
E
L
L
K
Q
A
Y
D
K
V
R
E
I
G
F
E
L
I
N
I
D
I
C
V
M
A
Q
S
P
K
L
K
D
F
K
Q
A
M
Q
S
N
I
A
H
T
L
D
L
D
E
F
R
I
N
V
K
A
T
T
T
E
K
L
G
F
I
G
R
K
E
G
M
A
V
L
S
S
V
N
L
K
Y
65
PsiBlast_CBE
87.41
58%
-120
- C10 -
3QHD
5
ISPF_BURP1
B:
[24-179]
-
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
P
--
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
104
HHSearch
85.97
45%
-117
- C10 -
2PMP
4
ISPF_ARATH
A:
[3-159]
P
F
R
I
G
H
G
F
D
L
H
R
L
E
P
G
Y
P
--
L
I
I
G
G
I
V
I
P
H
D
R
G
C
E
A
H
S
D
G
D
V
L
L
H
C
V
V
D
A
I
L
G
A
L
G
L
P
D
I
G
Q
I
F
P
D
S
D
P
K
W
K
G
A
A
S
S
V
F
I
K
E
A
V
R
L
M
D
E
A
G
Y
E
I
G
N
L
D
A
T
L
I
L
Q
R
P
K
I
S
P
H
K
E
T
I
R
S
N
L
S
K
L
L
G
A
D
P
S
V
V
N
L
K
A
K
T
H
E
K
V
D
S
L
G
E
N
R
S
I
A
A
H
T
V
I
L
L
M
K
107
HHSearch
79.93
36%
-114
- C10 -
2UZH
7
?
A:
[5-158]
L
P
R
V
G
L
G
T
D
V
H
P
I
E
A
G
R
P
--
C
R
L
L
C
L
E
F
D
D
A
D
G
C
A
--
S
D
G
D
V
A
A
H
A
L
C
D
A
L
L
S
A
A
G
L
G
D
L
G
T
I
F
G
T
D
R
P
Q
W
R
G
A
S
G
A
D
M
I
R
H
V
R
G
L
V
E
N
A
G
F
V
I
G
N
A
T
V
Q
V
I
G
N
R
P
K
V
G
P
R
R
E
E
A
Q
Q
V
L
S
E
L
V
G
A
---
P
V
S
V
S
A
T
T
T
D
G
L
G
L
T
G
R
G
E
G
L
A
A
I
A
T
A
L
V
A
A