@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0750: (2016-01-17 )
MTDNDDRIKLEASWKEALREEFDKPYMKQLGEFLRQEKAAGKVIFPPGPLIFNALNTTPLENVKVVIIGQDPYHGPGQAHGLCFSVQPGVPTPPSLQNIYKELNRDLNIPIPNNGYLQRWAEQGVLLLNTSLTVEQAKAGSHANAGWQPFTDRVIEVVNERCERLVFLLWGSHAQSKQKLIDPQRHLILKSAHPSPLSAYRGFLGNGHFSRTNKFLEQNGKTPIDWSLPDL
Atome Classification :
(59 SA)
.........10........20----........30.........40........50........60........70........80........90.........100.-....-.-.110........120.......130.......140.-.-.....150.......160-.......170.......180.......190.....-------..200-----.........210.......220.......230
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTDND
D
R
I
K
L
E
A
S
W
K
E
A
L
R
E
E----F
D
K
P
Y
M
K
Q
L
-
G
E
F
L
R
Q
E
KAAG
K
V
IFPPGP
L
I
F
NALNTTPLE
N
V
K
V
V
I
I
GQDPYHGPGQAH
G
L
C
F
SVQPGV-PTPP
S
L
Q
N
I
Y
K
E
L
-NRDL-N-IPI-PN
N
G
Y
L
Q
R
W
A
EQ
G
V
L
L
LN
T
S
L
T
V
E
Q
AKAGSHA-N-AGWQ
P
F
T
D
R
V
I
E
V
V
N
E
R
C
-
E
R
L
V
F
L
L
WGSHA
Q
S
K
Q
KLIDP
Q
R
H
L
I
L
KSAHPS
P
L
-------
S
A
Y
-------
R
G
F
LGNGH
F
S
R
T
N
K
F
L
E
QNGKTPIDWSLPDL-
3
PsiBlast_PDB
93.44
54%
-94
- C8 -
3ZOQ
2
UNG_BACSU
A:
[5-225]
---------
L
Q
D
S
W
W
N
Q
L
K
E
E
----
F
E
K
P
Y
Y
Q
E
L
-
R
E
M
L
K
R
E
Y
A
E
-
Q
T
I
Y
P
D
S
R
D
I
F
N
A
L
H
Y
T
S
Y
D
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
Q
G
L
S
F
S
V
K
P
G
V
-
K
Q
P
P
S
L
K
N
I
F
L
E
L
-
Q
Q
D
I
-
G
-
C
S
I
-
P
N
H
G
S
L
V
S
W
A
K
Q
G
V
L
L
L
N
T
V
L
T
V
R
R
G
Q
A
N
S
H
K
-
G
-
K
G
W
E
R
L
T
D
R
I
I
D
V
L
S
E
R
E
-
R
P
V
I
F
I
L
W
G
R
H
A
Q
M
K
K
E
R
I
D
T
S
K
H
F
I
I
E
S
T
H
P
S
P
F
-------
S
A
R
-------
N
G
F
F
G
S
R
P
F
S
R
A
N
A
Y
L
E
K
M
G
E
A
P
I
D
W
C
I
K
D
L
-
4
PsiBlast_PDB
93.34
54%
-92
- C8 -
3ZOR
-
UNG_BACSU
A:
[5-225]
---------
L
Q
D
S
W
W
N
Q
L
K
E
E
----
F
E
K
P
Y
Y
Q
E
L
-
R
E
M
L
K
R
E
Y
A
E
-
Q
T
I
Y
P
D
S
R
D
I
F
N
A
L
H
Y
T
S
Y
D
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
Q
G
L
S
F
S
V
K
P
G
V
-
K
Q
P
P
S
L
K
N
I
F
L
E
L
-
Q
Q
D
I
-
G
-
C
S
I
-
P
N
H
G
S
L
V
S
W
A
K
Q
G
V
L
L
L
N
T
V
L
T
V
R
R
G
Q
A
N
S
H
K
-
G
-
K
G
W
E
R
L
T
D
R
I
I
D
V
L
S
E
R
E
-
R
P
V
I
F
I
L
W
G
R
H
A
Q
M
K
K
E
R
I
D
T
S
K
H
F
I
I
E
S
T
H
P
S
P
F
-------
S
A
R
-------
N
G
F
F
G
S
R
P
F
S
R
A
N
A
Y
L
E
K
M
G
E
A
P
I
D
W
C
I
K
D
L
-
2
PsiBlast_PDB
93.27
58%
-89
- C8 -
2JHQ
1
UNG_VIBCH
A:
[6-224]
------------
T
W
H
D
V
I
G
N
E
----
K
Q
Q
A
Y
F
Q
Q
T
-
L
Q
F
V
E
S
Q
R
Q
A
G
K
V
I
Y
P
P
A
K
D
V
F
N
A
F
R
F
T
E
F
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
L
P
G
V
-
K
T
P
P
S
L
V
N
I
Y
K
E
L
-
A
Q
D
I
P
G
-
F
Q
I
-
P
P
H
G
Y
L
Q
S
W
A
Q
Q
G
V
L
L
L
N
T
V
L
T
V
E
Q
G
M
A
H
S
H
A
-
N
-
T
G
W
E
T
F
T
D
R
V
I
D
A
L
N
Q
H
R
-
N
G
L
I
F
L
L
W
G
S
H
A
Q
K
K
G
Q
M
I
D
R
Q
R
H
H
V
L
M
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
L
G
C
R
H
F
S
K
T
N
Q
L
L
Q
A
Q
G
I
A
P
I
N
W
Q
-
P
E
L
-
6
PsiBlast_PDB
92.87
56%
-91
- C8 -
1UUG
-
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
R
G
E
T
P
I
D
W
M
P
V
L
P
-
66
Fugue
92.83
55%
-89
- C8 -
1UUG
-
UNG_ECOLI
A:
[5-226]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
R
G
E
T
P
I
D
W
M
P
V
L
P
A
15
PsiBlast_PDB
92.67
55%
-94
- C8 -
4EUG
-
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
Q
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
13
PsiBlast_PDB
92.48
55%
-90
- C8 -
3EUG
2
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
H
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
24
PsiBlast_CBE
92.47
53%
-91
- C8 -
3FCI
4
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
20
PsiBlast_PDB
92.47
55%
-88
- C8 -
2BOO
3
UNG_DEIRA
A:
[23-241]
---------
L
P
E
D
W
Q
E
A
L
L
P
E
----
F
S
A
P
Y
F
H
E
L
-
T
D
F
L
R
Q
E
R
K
E
-
Y
T
I
Y
P
P
A
P
D
V
F
N
A
L
R
Y
T
P
L
G
E
V
K
V
L
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
S
F
S
V
R
P
G
V
-
R
V
P
P
S
L
R
N
I
Y
K
E
L
-
T
E
D
I
P
G
-
F
V
A
-
P
K
H
G
Y
L
R
S
W
A
E
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
G
Q
A
N
S
H
Q
-
G
-
K
G
W
E
H
F
T
D
A
V
I
K
A
V
N
A
K
E
-
E
R
V
V
F
I
L
W
G
S
Y
A
R
K
K
K
K
L
I
T
G
K
N
H
V
V
I
E
S
G
H
P
S
P
L
-------
S
E
--------
Q
Y
F
F
G
T
R
P
F
S
K
T
N
E
A
L
E
K
A
G
R
G
P
V
E
W
Q
L
P
A
T
-
32
PsiBlast_CBE
92.12
53%
-93
- C8 -
1EMH
2
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
5
PsiBlast_PDB
92.07
56%
-92
- C8 -
1EUG
-
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
26
PsiBlast_CBE
92.03
53%
-91
- C8 -
2OYT
2
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
29
PsiBlast_CBE
91.94
53%
-90
- C8 -
1SSP
3
UNG_HUMAN
E:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
25
PsiBlast_CBE
91.88
53%
-90
- C8 -
3FCF
3
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
34
PsiBlast_CBE
91.77
53%
-89
- C8 -
2SSP
2
UNG_HUMAN
E:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
A
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
21
PsiBlast_CBE
91.74
53%
-91
- C8 -
3FCL
8
UNG_HUMAN
B:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
19
PsiBlast_PDB
91.71
55%
-93
- C8 -
3UFM
3
UNG_DEIRA
A:
[23-241]
---------
L
P
E
D
W
Q
E
A
L
L
P
E
----
F
S
A
P
Y
F
H
E
L
-
T
D
F
L
R
Q
E
R
K
E
-
Y
T
I
Y
P
P
A
P
D
V
F
N
A
L
R
Y
T
P
L
G
E
V
K
V
L
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
S
F
S
V
R
P
G
V
-
R
V
P
P
S
L
R
N
I
Y
K
E
L
-
T
E
D
I
P
G
-
F
V
A
-
P
K
H
G
Y
L
R
S
W
A
E
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
G
Q
A
N
S
H
Q
-
G
-
K
G
W
E
H
F
T
D
A
V
I
K
A
V
N
A
K
E
-
E
R
V
V
F
I
L
W
G
S
Y
A
R
K
K
K
K
L
I
T
G
K
N
H
V
V
I
E
S
G
H
P
S
P
L
-------
S
E
--------
Q
Y
F
F
G
T
R
P
F
S
K
T
N
E
A
L
E
K
A
G
R
G
P
V
E
W
Q
L
P
A
T
-
76
HHSearch
91.66
52%
-88
* C8 *
3FCI
4
UNG_HUMAN
A:
[2-223]
-------
E
F
F
G
E
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
-
H
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
-
E
D
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
77
HHSearch
91.64
55%
-89
- C8 -
3UF7
6
UNG_ECOLI
A:
[3-224]
---------
N
E
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
-
P
G
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
R
G
E
T
P
I
D
W
M
P
V
L
P
-
23
PsiBlast_CBE
91.61
53%
-91
- C8 -
3FCK
1
UNG_HUMAN
B:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
28
PsiBlast_CBE
91.53
53%
-88
- C8 -
2HXM
1
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
27
PsiBlast_CBE
91.44
53%
-89
- C8 -
2OXM
2
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
16
PsiBlast_PDB
91.33
55%
-89
- C8 -
5EUG
1
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
Q
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
11
PsiBlast_PDB
91.33
56%
-89
- C8 -
3UF7
6
UNG_ECOLI
A:
[4-220]
----------
E
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
Y
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
R
G
E
T
P
I
D
W
M
P
V
L
P
-
30
PsiBlast_CBE
91.14
53%
-90
- C8 -
1Q3F
4
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
12
PsiBlast_PDB
91.08
55%
-91
- C8 -
2EUG
1
UNG_ECOLI
A:
[5-220]
-----------
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
H
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
33
PsiBlast_CBE
91.07
53%
-86
- C8 -
3TKB
2
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
-
E
-
G
F
V
H
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
R
E
L
---
18
PsiBlast_PDB
90.98
56%
-84
- C8 -
4UQM
4
?
A:
[23-241]
---------
L
P
E
D
W
Q
E
A
L
L
P
E
----
F
S
A
P
Y
F
H
E
L
-
T
D
F
L
R
Q
E
R
K
E
-
Y
T
I
Y
P
P
A
P
D
V
F
N
A
L
R
Y
T
P
L
G
E
V
K
V
L
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
S
F
S
V
R
P
G
V
-
R
V
P
P
S
L
R
N
I
Y
K
E
L
-
T
E
D
I
P
G
-
F
V
A
-
P
K
H
G
Y
L
R
S
W
A
E
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
A
Q
A
N
S
H
Q
-
G
-
K
G
W
E
H
F
T
D
A
V
I
K
A
V
N
A
K
E
-
E
R
V
V
F
I
L
W
G
S
Y
A
R
K
K
K
K
L
I
T
G
K
N
H
V
V
I
E
S
G
H
P
S
P
L
-------
S
E
--------
Q
Y
F
F
G
T
R
P
F
S
K
T
N
E
A
L
E
K
A
G
R
G
P
V
E
W
Q
L
P
A
T
-
37
PsiBlast_CBE
90.94
51%
-85
- C8 -
1OKB
2
?
A:
[7-220]
------------
T
W
R
R
E
L
A
A
E
----
F
E
K
P
Y
F
K
Q
L
-
M
S
F
V
A
D
E
R
S
R
-
H
T
V
Y
P
P
A
D
Q
V
Y
S
W
T
E
M
C
D
I
Q
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
K
P
V
-
P
P
P
P
S
L
V
N
I
Y
K
E
L
-
C
T
D
I
-
D
G
F
K
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
D
-
R
G
W
E
T
F
T
D
A
V
I
K
W
L
S
V
N
R
-
E
G
V
V
F
L
L
W
G
S
Y
A
H
K
K
G
A
T
I
D
R
K
R
H
H
V
L
Q
A
V
H
P
S
P
L
-------
S
A
H
-------
R
G
F
L
G
C
K
H
F
S
K
A
N
G
L
L
K
L
S
G
T
E
P
I
N
W
R
A
L
---
36
PsiBlast_CBE
90.90
51%
-85
- C8 -
1OKB
2
?
B:
[7-220]
------------
T
W
R
R
E
L
A
A
E
----
F
E
K
P
Y
F
K
Q
L
-
M
S
F
V
A
D
E
R
S
R
-
H
T
V
Y
P
P
A
D
Q
V
Y
S
W
T
E
M
C
D
I
Q
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
K
P
V
-
P
P
P
P
S
L
V
N
I
Y
K
E
L
-
C
T
D
I
-
D
G
F
K
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
D
-
R
G
W
E
T
F
T
D
A
V
I
K
W
L
S
V
N
R
-
E
G
V
V
F
L
L
W
G
S
Y
A
H
K
K
G
A
T
I
D
R
K
R
H
H
V
L
Q
A
V
H
P
S
P
L
-------
S
A
H
-------
R
G
F
L
G
C
K
H
F
S
K
A
N
G
L
L
K
L
S
G
T
E
P
I
N
W
R
A
L
---
31
PsiBlast_CBE
90.79
53%
-91
- C8 -
1EMJ
3
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
22
PsiBlast_CBE
90.79
53%
-87
- C8 -
3FCL
7
UNG_HUMAN
A:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
14
PsiBlast_PDB
90.69
55%
-90
- C8 -
1FLZ
1
UNG_ECOLI
A:
[3-219]
----------
E
L
T
W
H
D
V
L
A
E
E
----
K
Q
Q
P
H
F
L
N
T
-
L
Q
T
V
A
S
E
R
Q
S
G
V
T
I
Y
P
P
Q
K
D
V
F
N
A
F
R
F
T
E
L
G
D
V
K
V
V
I
L
G
Q
D
P
Y
H
G
P
G
Q
A
H
G
L
A
F
S
V
R
P
G
I
-
A
I
P
P
S
L
L
N
M
Y
K
E
L
-
E
N
T
I
P
G
-
F
T
R
-
P
N
H
G
Y
L
E
S
W
A
R
Q
G
V
L
L
L
N
T
V
L
T
V
R
A
G
Q
A
H
S
H
A
-
S
-
L
G
W
E
T
F
T
D
K
V
I
S
L
I
N
Q
H
R
-
E
G
V
V
F
L
L
W
G
S
H
A
Q
K
K
G
A
I
I
D
K
Q
R
H
H
V
L
K
A
P
H
P
S
P
L
-------
S
A
H
-------
R
G
F
F
G
C
N
H
F
V
L
A
N
Q
W
L
E
Q
H
G
E
T
P
I
D
W
M
P
V
L
P
-
35
PsiBlast_CBE
90.60
53%
-89
- C8 -
4SKN
3
UNG_HUMAN
E:
[7-220]
------------
S
W
K
K
H
L
S
G
E
----
F
G
K
P
Y
F
I
K
L
-
M
G
F
V
A
E
E
R
K
H
-
Y
T
V
Y
P
P
P
H
Q
V
F
T
W
T
Q
M
C
D
I
K
D
V
K
V
V
I
L
G
Q
N
P
Y
H
G
P
N
Q
A
H
G
L
C
F
S
V
Q
R
P
V
-
P
P
P
P
S
L
E
N
I
Y
K
E
L
-
S
T
D
I
E
D
-
F
V
H
-
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
L
L
L
N
A
V
L
T
V
R
A
H
Q
A
N
S
H
K
-
E
-
R
G
W
E
Q
F
T
D
A
V
V
S
W
L
N
Q
N
S
-
N
G
L
V
F
L
L
W
G
S
Y
A
Q
K
K
G
S
A
I
D
R
K
R
H
H
V
L
Q
T
A
H
P
S
P
R
-------
S
V
Y
-------
R
G
F
F
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
G
K
K
P
I
D
W
K
E
L
---
78
HHSearch
89.72
50%
-83
- C8 -
3CXM
2
?
A:
[33-263]
------
G
L
I
T
N
P
E
W
R
D
F
L
A
P
I
TADS
W
R
K
G
A
F
I
R
I
-
E
R
F
L
D
E
E
K
E
K
G
R
V
I
L
P
P
A
A
D
I
F
N
A
F
N
S
C
P
F
R
G
L
K
V
V
L
L
G
Q
D
P
Y
H
D
L
H
Q
A
H
G
L
C
F
S
V
L
P
E
V
-
P
L
P
P
S
L
R
N
I
Y
K
E
L
-
T
T
D
I
A
G
-
F
Q
A
-
P
K
H
G
Y
L
Q
S
W
S
E
Q
G
M
L
M
L
N
A
T
L
T
V
E
A
H
K
A
N
S
H
S
-
K
T
S
G
W
A
A
F
T
D
A
V
I
Q
H
L
S
Q
H
H
P
N
R
L
V
F
L
L
W
G
G
Y
A
Q
Q
K
K
R
L
I
D
A
N
R
H
V
V
L
E
N
V
H
P
S
P
L
-------
S
A
N
-------
R
G
W
F
G
C
R
C
F
S
A
C
N
E
A
L
Q
R
M
S
H
L
P
M
H
W
Q
L
P
L
N
-
44
PsiBlast_CBE
89.20
44%
-97
- C8 -
4WS5
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
58
PsiBlast_CBE
89.07
44%
-94
- C8 -
3A7N
2
UNG_MYCTU
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
55
PsiBlast_CBE
88.34
44%
-91
- C8 -
4WRU
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
80
HHSearch
88.09
45%
-88
- C8 -
2J8X
1
UNG_EBVB9
A:
[3-231]
------
N
L
L
L
P
D
L
W
L
D
F
L
Q
L
S
P
---
I
F
Q
R
K
L
A
A
V
-
I
A
C
V
R
R
L
R
-
T
Q
A
T
V
Y
P
E
E
D
M
C
M
A
W
A
R
F
C
D
P
S
D
I
K
V
V
I
L
G
Q
D
P
Y
H
G
-
G
Q
A
N
G
L
A
F
S
V
A
Y
G
F
-
P
V
P
P
S
L
R
N
I
Y
A
E
L
-
H
R
S
L
-
P
E
F
S
P
-
P
D
H
G
C
L
D
A
W
A
S
Q
G
V
L
L
L
N
T
I
L
T
V
Q
K
G
K
P
G
S
H
A
-
D
-
I
G
W
A
W
F
T
D
H
V
I
S
L
L
S
E
R
L
-
K
A
C
V
F
M
L
W
G
A
K
A
G
D
K
A
S
L
I
N
S
K
K
H
L
V
L
T
S
Q
H
P
S
P
L
-------
A
Q
N
STRKSAQ
Q
K
F
L
G
N
N
H
F
V
L
A
N
N
F
L
R
E
K
G
L
G
E
I
D
W
R
L
----
48
PsiBlast_CBE
87.86
44%
-92
- C8 -
4WS1
9
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
49
PsiBlast_CBE
87.83
44%
-90
- C8 -
4WS0
8
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
42
PsiBlast_CBE
87.79
44%
-89
- C8 -
4WS7
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
57
PsiBlast_CBE
87.43
44%
-90
- C8 -
4WPK
2
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
41
PsiBlast_CBE
87.32
44%
-89
- C8 -
4WS8
2
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
38
PsiBlast_CBE
87.29
51%
-89
- C8 -
3CXM
2
?
A:
[50-262]
-------------------
D
S
----
W
R
K
G
A
F
I
R
I
-
E
R
F
L
D
E
E
K
E
K
G
R
V
I
L
P
P
A
A
D
I
F
N
A
F
N
S
C
P
F
R
G
L
K
V
V
L
L
G
Q
D
P
Y
H
D
L
H
Q
A
H
G
L
C
F
S
V
L
P
E
V
-
P
L
P
P
S
L
R
N
I
Y
K
E
L
-
T
T
D
I
A
G
-
F
Q
A
-
P
K
H
G
Y
L
Q
S
W
S
E
Q
G
M
L
M
L
N
A
T
L
T
V
E
A
H
K
A
N
S
H
S
K
T
-
S
G
W
A
A
F
T
D
A
V
I
Q
H
L
S
Q
H
H
P
N
R
L
V
F
L
L
W
G
G
Y
A
Q
Q
K
K
R
L
I
D
A
N
R
H
V
V
L
E
N
V
H
P
S
P
L
-------
S
A
N
-------
R
G
W
F
G
C
R
C
F
S
A
C
N
E
A
L
Q
R
M
S
H
L
P
M
H
W
Q
L
P
L
N
-
47
PsiBlast_CBE
87.22
44%
-92
- C8 -
4WS2
10
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
56
PsiBlast_CBE
87.16
44%
-92
- C8 -
4WPL
11
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
54
PsiBlast_CBE
87.14
44%
-87
- C8 -
4WRV
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
50
PsiBlast_CBE
87.07
44%
-92
- C8 -
4WRZ
4
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
43
PsiBlast_CBE
86.55
44%
-90
- C8 -
4WS6
11
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
45
PsiBlast_CBE
86.54
44%
-89
- C8 -
4WS4
10
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
46
PsiBlast_CBE
86.49
44%
-89
- C8 -
4WS3
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
51
PsiBlast_CBE
86.40
44%
-89
- C8 -
4WRY
3
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
53
PsiBlast_CBE
85.30
44%
-85
- C8 -
4WRW
7
?
A:
[21-238]
---------
V
E
R
G
W
A
A
A
L
E
P
V
----
A
D
Q
--
V
A
H
M
-
G
Q
F
L
R
A
E
I
A
A
G
R
R
Y
L
P
A
G
S
N
V
L
R
A
F
-
T
F
P
F
D
N
V
R
V
L
I
V
G
Q
D
P
Y
P
T
P
G
H
A
V
G
L
S
F
S
V
A
P
D
V
R
P
W
P
R
S
L
A
N
I
F
D
E
Y
-
T
A
D
L
-
G
-
Y
P
L
-
P
S
N
G
D
L
T
P
W
A
Q
R
G
V
L
L
L
N
R
V
L
T
V
R
P
S
N
P
A
S
H
R
-
G
-
K
G
W
E
A
V
T
E
C
A
I
R
A
L
A
A
R
A
-
A
P
L
V
A
I
L
W
G
R
D
A
S
T
L
K
P
M
L
A
A
G
N
C
V
A
I
E
S
P
H
P
S
P
L
-------
S
A
S
-------
R
G
F
F
G
S
R
P
F
S
R
A
N
E
L
L
V
G
M
G
A
E
P
I
D
W
R
L
P
---
61
PsiBlast_CBE
84.49
41%
-86
- C8 -
1LAU
1
UNG_HHV11
E:
[28-244]
---------
I
D
D
A
W
R
P
L
M
E
P
E
----
L
A
N
P
L
T
A
H
L
L
A
E
Y
N
R
--
R
C
Q
T
E
E
V
L
P
P
R
E
D
V
F
S
W
T
R
Y
C
T
P
D
E
V
R
V
V
I
I
G
Q
D
P
Y
H
H
P
G
Q
A
H
G
L
A
F
S
V
R
A
N
V
-
P
P
P
P
S
L
R
N
V
L
A
A
V
K
N
C
Y
P
-
E
-
A
R
M
-
S
G
H
G
C
L
E
K
W
A
R
D
G
V
L
L
L
N
T
T
L
T
V
K
R
G
A
A
A
S
H
S
-
R
-
I
G
W
D
R
F
V
G
G
V
I
R
R
L
A
A
R
R
-
P
G
L
V
F
M
L
W
G
T
H
A
Q
N
A
I
R
-
P
D
P
R
V
H
C
V
L
K
F
S
H
P
S
P
L
-------
S
K
V
--------
P
F
G
T
C
Q
H
F
L
V
A
N
R
Y
L
E
T
R
S
I
S
P
I
D
W
S
V
----
59
PsiBlast_CBE
84.27
41%
-83
- C8 -
1UDH
3
UNG_HHV11
A:
[28-244]
---------
I
D
D
A
W
R
P
L
M
E
P
E
----
L
A
N
P
L
T
A
H
L
L
A
E
Y
N
R
--
R
C
Q
T
E
E
V
L
P
P
R
E
D
V
F
S
W
T
R
Y
C
T
P
D
E
V
R
V
V
I
I
G
Q
D
P
Y
H
H
P
G
Q
A
H
G
L
A
F
S
V
R
A
N
V
-
P
P
P
P
S
L
R
N
V
L
A
A
V
K
N
C
Y
P
-
E
-
A
R
M
-
S
G
H
G
C
L
E
K
W
A
R
D
G
V
L
L
L
N
T
T
L
T
V
K
R
G
A
A
A
S
H
S
-
R
-
I
G
W
D
R
F
V
G
G
V
I
R
R
L
A
A
R
R
-
P
G
L
V
F
M
L
W
G
T
H
A
Q
N
A
I
R
-
P
D
P
R
V
H
C
V
L
K
F
S
H
P
S
P
L
-------
S
K
V
--------
P
F
G
T
C
Q
H
F
L
V
A
N
R
Y
L
E
T
R
S
I
S
P
I
D
W
S
V
----
65
PsiBlast_CBE
82.91
40%
-90
- C8 -
2C53
5
UNG_HHV11
A:
[28-244]
---------
I
D
D
A
W
R
P
L
M
E
P
E
----
L
A
N
P
L
T
A
H
L
L
A
E
Y
N
R
--
R
C
Q
T
E
E
V
L
P
P
R
E
D
V
F
S
W
T
R
Y
C
T
P
D
E
V
R
V
V
I
I
G
Q
N
P
Y
H
H
P
G
Q
A
H
G
L
A
F
S
V
R
A
N
V
-
P
P
P
P
S
L
R
N
V
L
A
A
V
K
N
C
Y
P
-
E
-
A
R
M
-
S
G
H
G
C
L
E
K
W
A
R
D
G
V
L
L
L
N
T
T
L
T
V
K
R
G
A
A
A
S
H
S
-
R
-
I
G
W
D
R
F
V
G
G
V
I
R
R
L
A
A
R
R
-
P
G
L
V
F
M
L
W
G
T
H
A
Q
N
A
I
R
-
P
D
P
R
V
H
C
V
L
K
F
S
N
P
S
P
L
-------
S
K
V
--------
P
F
G
T
C
Q
H
F
L
V
A
N
R
Y
L
E
T
R
S
I
S
P
I
D
W
S
V
----
39
PsiBlast_CBE
82.41
54%
-102
- C8 -
2J8X
1
UNG_EBVB9
C:
[57-231]
-----------------------------------------------------------------
S
D
I
K
V
V
I
L
G
Q
D
P
Y
H
G
-
G
Q
A
N
G
L
A
F
S
V
A
Y
G
F
-
P
V
P
P
S
L
R
N
I
Y
A
E
L
-
H
R
S
L
P
E
-
F
S
P
-
P
D
H
G
C
L
D
A
W
A
S
Q
G
V
L
L
L
N
T
I
L
T
V
Q
K
G
K
P
G
S
H
A
-
D
-
I
G
W
A
W
F
T
D
H
V
I
S
L
L
S
E
R
L
-
K
A
C
V
F
M
L
W
G
A
K
A
G
D
K
A
S
L
I
N
S
K
K
H
L
V
L
T
S
Q
H
P
S
P
L
AQNSTRK
S
A
Q
-------
Q
K
F
L
G
N
N
H
F
V
L
A
N
N
F
L
R
E
K
G
L
G
E
I
D
W
R
L
----
40
PsiBlast_CBE
81.96
54%
-99
- C8 -
2J8X
1
UNG_EBVB9
A:
[57-231]
-----------------------------------------------------------------
S
D
I
K
V
V
I
L
G
Q
D
P
Y
H
G
-
G
Q
A
N
G
L
A
F
S
V
A
Y
G
F
-
P
V
P
P
S
L
R
N
I
Y
A
E
L
-
H
R
S
L
P
E
-
F
S
P
-
P
D
H
G
C
L
D
A
W
A
S
Q
G
V
L
L
L
N
T
I
L
T
V
Q
K
G
K
P
G
S
H
A
-
D
-
I
G
W
A
W
F
T
D
H
V
I
S
L
L
S
E
R
L
-
K
A
C
V
F
M
L
W
G
A
K
A
G
D
K
A
S
L
I
N
S
K
K
H
L
V
L
T
S
Q
H
P
S
P
L
AQNSTRK
S
A
Q
-------
Q
K
F
L
G
N
N
H
F
V
L
A
N
N
F
L
R
E
K
G
L
G
E
I
D
W
R
L
----