@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00280: (2016-06-01 )
MSGLFITFEGPEGAGKTTVLQEIKNILTAEGLQVMATREPGGIDIAEQIREVILNENNILMDPKTEALLYAAARRQHLVEKVKPALEQGFIVLCDRFIDSSLAYQGYARGLGIDEVLSINEFAIGDMMPHVTVYFSIDPEEGLKRIYANGSREKNRLDLEKLDFHTKVQEGYQELMKRFPERFHSVDAGQSKDLVVQDVLKVIDEALKKIQL
Atome Classification :
(67 SA)
.........10........20----........30---..-------.-..-.-..-.40........50.....---.---.-.---60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180....-..-.190.......200.......210
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
G
L
F
I
T
F
EGPEGAG
K
T
T
V
L
Q
----
E
I
K
N
I
L
T
AE----G
L
-------
Q
-
V
M
-
A
-TR-EPGGI
D
I
A
E
Q
I
R
E
V
ILNE---N---
N
-
I
---
L
MDPK
T
E
A
L
L
Y
A
A
A
R
R
Q
H
L
V
E
K
V
K
P
A
L
EQ
G
F
I
V
L
C
D
R
F
I
D
S
S
L
A
Y
Q
G
YARGL
G
I
D
E
V
L
S
I
N
E
FAIGDMMP
H
V
T
V
Y
F
S
I
D
P
E
E
G
L
K
R
I
YANGSREKNRL
D
L
E
K
L
D
F
H
T
K
V
Q
E
G
Y
Q
E
L
M
K
R
F
P
E
R
FHSV-DA-GQSK
D
L
V
V
Q
D
V
L
K
V
I
D
E
A
L
K
KIQL
25
PsiBlast_CBE
96.39
53%
-96
- C2 -
4DWJ
1
KTHY_STAAM
D:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
5
PsiBlast_PDB
95.99
53%
-116
- C- -
2CCJ
5
KTHY_STAAM
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
---
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
----
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
24
PsiBlast_CBE
95.55
53%
-92
- C2 -
4DWJ
1
KTHY_STAAM
F:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
--
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
1
PsiBlast_PDB
95.55
53%
-96
- C2 -
4DWJ
1
KTHY_STAAM
A:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
18
PsiBlast_PDB
94.51
53%
-97
- C2 -
4MQB
2
KTHY_STAAM
A:
[7-208]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
--
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
30
PsiBlast_CBE
94.27
53%
-108
- C2 -
4QGH
2
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
-------
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
21
PsiBlast_CBE
94.20
53%
-105
- C2 -
4EAQ
1
KTHY_STAAM
B:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
26
PsiBlast_CBE
94.17
53%
-94
- C2 -
4DWJ
1
KTHY_STAAM
C:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
-
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
9
PsiBlast_PDB
93.70
53%
-107
- C2 -
4HEJ
1
KTHY_STAAN
A:
[4-203]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-----
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
----
29
PsiBlast_CBE
93.65
53%
-107
- C2 -
4XWA
2
KTHY_STAA1
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
28
PsiBlast_CBE
93.58
53%
-115
- C- -
2CCG
1
KTHY_STAAM
B:
[24-225]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
-----
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
32
PsiBlast_CBE
93.40
53%
-105
- C2 -
4QGA
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
31
PsiBlast_CBE
93.19
53%
-110
- C2 -
4QGG
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
27
PsiBlast_CBE
92.80
53%
-93
- C2 -
4DWJ
1
KTHY_STAAM
B:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
D
Q
N
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
36
PsiBlast_CBE
92.70
53%
-106
- C2 -
4HDC
1
KTHY_STAAN
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
34
PsiBlast_CBE
92.68
53%
-105
- C2 -
4HLD
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
17
PsiBlast_PDB
92.59
53%
-101
- C2 -
4XWA
1
KTHY_STAA1
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
R
----
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
33
PsiBlast_CBE
92.42
53%
-105
- C2 -
4QG7
1
KTHY_STAAR
B:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
128
HHSearch
92.04
53%
-101
* C2 *
4EAQ
1
KTHY_STAAM
A:
[24-228]
A
M
S
A
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
-----
D
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
---------------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
35
PsiBlast_CBE
91.97
53%
-105
- C2 -
4HLC
1
KTHY_STAAR
B:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
-
S
------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
12
PsiBlast_PDB
91.62
53%
-100
- C2 -
4QG7
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
8
PsiBlast_PDB
91.49
53%
-103
- C2 -
4HDC
1
KTHY_STAAN
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
7
PsiBlast_PDB
91.37
53%
-101
- C2 -
4GSY
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
16
PsiBlast_PDB
91.32
53%
-95
- C2 -
4QGH
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
--
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
15
PsiBlast_PDB
91.06
53%
-101
- C2 -
4QGG
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
------------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
14
PsiBlast_PDB
90.97
53%
-102
- C2 -
4QGF
1
KTHY_STAAR
A:
[4-205]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
---------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
I
--
11
PsiBlast_PDB
90.68
53%
-101
- C2 -
4HLD
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
119
HHSearch
90.40
53%
-102
- C2 -
4HLC
1
KTHY_STAAR
A:
[2-203]
--
S
A
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
-----
D
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---------
D
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
--------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
----
13
PsiBlast_PDB
90.37
53%
-98
- C2 -
4QGA
1
KTHY_STAAR
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
--------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
2
PsiBlast_PDB
90.21
53%
-99
- C2 -
4EAQ
1
KTHY_STAAM
A:
[28-228]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
---------------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
N
------
R
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
10
PsiBlast_PDB
89.65
53%
-99
- C2 -
4HLC
1
KTHY_STAAR
A:
[4-203]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
---
N
---
D
------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
K
--------
L
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
N
E
S
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
----
120
HHSearch
88.73
40%
-83
- C2 -
4EDH
5
KTHY_PSEAE
A:
[5-212]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
R
--
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
L
P
L
A
E
V
Q
A
G
L
D
R
L
L
P
N
L
L
E
R
L
N
-
6
PsiBlast_PDB
87.34
53%
-99
- C2 -
4GFD
1
KTHY_STAAM
A:
[4-204]
----
F
I
T
F
E
G
P
E
G
S
G
K
T
T
V
I
N
----
E
V
Y
H
R
L
V
K
D
-----
Y
-------
D
-
V
I
-
M
-
T
R
-
E
P
G
G
V
P
T
G
E
E
I
R
K
I
V
L
E
G
--------------
M
D
I
R
T
E
A
M
L
F
A
A
S
R
R
E
H
L
V
L
K
V
I
P
A
L
K
E
G
K
V
V
L
C
D
R
Y
I
D
S
S
L
A
Y
Q
G
Y
A
R
G
I
G
V
E
E
V
R
A
L
N
E
F
A
I
N
G
L
Y
P
D
L
T
I
Y
L
N
V
S
A
E
V
G
R
E
R
I
I
----------
D
Q
E
D
L
K
F
H
E
K
V
I
E
G
Y
Q
E
I
I
H
---
Q
R
F
K
S
V
-
N
A
-
D
Q
P
L
E
N
V
V
E
D
T
Y
Q
T
I
I
K
Y
L
E
K
---
51
PsiBlast_CBE
85.14
39%
-100
- C2 -
3HJN
3
KTHY_THEMA
A:
[1-192]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
----
L
L
A
Q
Y
L
E
K
R
----
G
K
-------
K
-
V
I
-
L
-
K
R
-
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
E
---
E
----------
V
T
P
K
A
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
-----
K
---
N
R
--
F
E
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
-
D
G
-
K
R
S
I
E
E
I
H
R
D
V
V
R
E
V
K
R
R
------
65
PsiBlast_CBE
85.02
34%
-89
- C2 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
----
V
V
V
E
T
L
E
Q
L
----
G
I
-------
R
-
D
M
-
V
F
T
R
-
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
D
I
---
K
---
S
-
V
GD
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
--
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
-
D
K
S
I
H
T
I
-
D
A
-
T
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
64
PsiBlast_CBE
84.40
34%
-89
- C2 -
5TMP
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
----
V
V
V
E
T
L
E
Q
L
----
G
I
-------
R
-
D
M
-
V
F
T
R
-
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
D
I
---
K
---
S
-
V
GD
E
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
--
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
-
D
K
S
I
H
T
I
-
D
A
-
T
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
129
HHSearch
84.23
34%
-89
- C2 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
----
V
V
V
E
T
L
E
Q
L
----
G
I
-------
R
-
D
M
-
V
-
F
T
R
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
D
I
---
K
SVG
D
-
E
---
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
E
L
--
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
D
-
K
S
I
H
T
I
-
D
A
-
T
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
131
HHSearch
84.04
39%
-99
- C2 -
3HJN
3
KTHY_THEMA
A:
[1-192]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
----
L
L
A
Q
Y
L
E
K
R
----
G
K
-------
K
-
V
I
-
L
-
K
R
-
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
E
-------------
E
V
T
P
K
A
E
L
F
L
F
L
A
S
R
N
L
L
-
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
K
---
N
-----
R
F
E
K
--
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
-
D
G
-
K
R
S
I
E
E
I
H
R
D
V
V
R
E
V
K
R
R
------
67
PsiBlast_CBE
83.84
35%
-83
- C2 -
3N2I
2
KTHY_VIBCH
A:
[25-232]
M
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
----
V
V
V
E
T
L
Q
Q
N
----
G
I
D------
H
-
I
T
-
R
-
T
R
-
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
E
---
H
P
--
G
-
E
---
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
--
A
R
G
--
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
-
D
D
S
V
V
M
I
-
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
---
130
HHSearch
83.77
36%
-83
- C2 -
3LV8
8
KTHY_VIBCH
A:
[26-232]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
----
V
V
V
E
T
L
Q
Q
N
----
G
I
-------
D
-
H
I
T
R
-
T
R
-
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
E
---
H
---
P
G
E
---
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-----
E
--
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
D
-
D
S
V
V
M
I
-
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
---
139
Fugue
83.58
34%
-92
- C2 -
4TMK
1
KTHY_ECOLI
A:
[2-211]
-
R
S
K
Y
I
V
I
E
G
L
E
G
A
G
K
T
T
A
R
N
----
V
V
V
E
T
L
E
Q
L
----
G
I
-------
R
D
M
V
-
F
-
T
R
-
E
P
G
G
T
Q
L
A
E
K
L
R
S
L
L
L
D
I
KSV
G
---
D
-
E
---
V
I
T
D
K
A
E
V
L
M
F
Y
A
A
R
V
Q
L
V
E
T
V
I
K
P
A
L
A
N
G
T
W
V
I
G
D
R
H
D
L
S
T
Q
A
Y
Q
G
G
G
R
G
I
D
Q
H
M
L
A
T
L
R
D
A
V
L
G
D
F
R
P
D
L
T
L
Y
L
D
V
T
P
E
V
G
L
K
R
A
R
A
R
G
--
E
L
D
R
I
E
Q
E
S
F
D
F
F
N
R
T
R
A
R
Y
L
E
L
A
A
Q
D
-
K
S
I
H
T
I
-
D
A
T-
Q
P
L
E
A
V
M
D
A
I
R
T
T
V
T
H
W
V
K
E
L
--
68
PsiBlast_CBE
83.56
35%
-85
- C2 -
3LV8
8
KTHY_VIBCH
A:
[26-233]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
----
V
V
V
E
T
L
Q
Q
N
----
G
I
D------
H
-
I
T
-
R
-
T
R
-
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
E
---
H
P
--
G
-
E
---
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
-------
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
-
D
D
S
V
V
M
I
-
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
V
--
66
PsiBlast_CBE
83.49
35%
-78
- C2 -
3N2I
2
KTHY_VIBCH
B:
[26-233]
-
N
A
K
F
I
V
I
E
G
L
E
G
A
G
K
S
T
A
I
Q
----
V
V
V
E
T
L
Q
Q
N
----
G
I
D------
H
-
I
T
-
R
-
T
R
-
E
P
G
G
T
L
L
A
E
K
L
R
A
L
V
K
E
E
---
H
P
--
G
-
E
---
E
L
Q
D
I
T
E
L
L
L
V
Y
A
A
R
V
Q
L
V
E
N
V
I
K
P
A
L
A
R
G
E
W
V
V
G
D
R
H
D
M
S
S
Q
A
Y
Q
G
G
G
R
Q
I
A
P
S
T
M
Q
S
L
K
Q
T
A
L
G
D
F
K
P
D
L
T
L
Y
L
D
I
D
P
K
L
G
L
E
R
--
A
R
G
R
G
E
L
D
R
I
E
K
M
D
I
S
F
F
E
R
A
R
E
R
Y
L
E
L
A
N
S
-
D
D
S
V
V
M
I
-
D
A
-
A
Q
S
I
E
Q
V
T
A
D
I
R
R
A
L
Q
D
W
L
S
Q
V
--
122
HHSearch
82.45
35%
-97
- C2 -
4S35
5
KTHY_AQUAE
A:
[1-193]
---
M
L
I
A
F
E
G
I
D
G
S
G
K
T
T
Q
A
K
----
K
L
Y
E
Y
L
K
Q
K
----
G
Y
-------
F
-
V
S
-
L
-
Y
R
-
E
P
G
G
T
K
V
G
E
V
L
R
E
I
L
L
T
E
-------------
E
L
D
E
R
T
E
L
L
L
F
E
A
S
R
S
K
L
I
E
E
K
I
I
P
D
L
K
R
D
K
V
V
I
L
D
R
F
V
L
S
T
I
A
Y
Q
G
Y
G
K
G
L
D
V
E
F
I
K
N
L
N
E
F
A
T
R
G
V
K
P
D
I
T
L
L
L
D
I
P
V
D
I
A
L
R
R
L
K
E
K
N
-----
R
F
E
N
--
K
E
F
L
E
K
V
R
K
G
F
L
E
L
A
K
E
E
-
E
N
V
V
V
I
-
D
A
-
S
G
E
E
E
E
V
F
K
E
I
L
R
A
L
S
G
V
L
-----
58
PsiBlast_CBE
82.02
35%
-91
- C2 -
4S35
6
KTHY_AQUAE
B:
[1-194]
---
M
L
I
A
F
E
G
I
D
G
S
G
K
T
T
Q
A
K
----
K
L
Y
E
Y
L
K
Q
K
----
G
Y
-------
F
-
V
S
-
L
-
Y
R
-
E
P
G
G
T
K
V
G
E
V
L
R
E
I
L
L
T
E
---
E
----------
L
D
E
R
T
E
L
L
L
F
E
A
S
R
S
K
L
I
E
E
K
I
I
P
D
L
K
R
D
K
V
V
I
L
D
R
F
V
L
S
T
I
A
Y
Q
G
Y
G
K
G
L
D
V
E
F
I
K
N
L
N
E
F
A
T
R
G
V
K
P
D
I
T
L
L
L
D
I
P
V
D
I
A
L
R
R
L
-----
K
E
K
N
R
--
F
E
N
K
E
F
L
E
K
V
R
K
G
F
L
E
L
A
K
E
-
E
E
N
V
V
V
I
-
D
A
-
S
G
E
E
E
E
V
F
K
E
I
L
R
A
L
S
G
V
L
R
----
50
PsiBlast_CBE
81.86
39%
-97
- C2 -
3HJN
2
KTHY_THEMA
B:
[1-188]
---
M
F
I
T
F
E
G
I
D
G
S
G
K
S
T
Q
I
Q
----
L
L
A
Q
Y
L
E
K
R
----
G
K
-------
K
-
V
I
-
L
-
K
R
-
E
P
G
G
T
E
T
G
E
K
I
R
K
I
L
L
E
E
---
E
----------
V
T
P
K
A
E
L
F
L
F
L
A
S
R
-
N
L
L
V
T
E
I
K
Q
Y
L
S
E
G
Y
A
V
L
L
D
R
Y
T
D
S
S
V
A
Y
Q
G
F
G
R
N
L
G
K
E
I
V
E
E
L
N
D
F
A
T
D
G
L
I
P
D
L
T
F
Y
I
D
V
D
V
E
T
A
L
K
R
---------
N
R
--
F
E
K
R
E
F
L
E
R
V
R
E
G
Y
L
V
L
A
R
E
H
P
E
R
I
V
V
L
-
D
G
-
K
R
S
I
E
E
I
H
R
D
V
V
R
E
----------
59
PsiBlast_CBE
81.73
35%
-89
- C2 -
4S35
5
KTHY_AQUAE
A:
[1-194]
---
M
L
I
A
F
E
G
I
D
G
S
G
K
T
T
Q
A
K
----
K
L
Y
E
Y
L
K
Q
K
----
G
Y
-------
F
-
V
S
-
L
-
Y
R
-
E
P
G
G
T
K
V
G
E
V
L
R
E
I
L
L
T
E
---
E
----------
L
D
E
R
T
E
L
L
L
F
E
A
S
R
S
K
L
I
E
E
K
I
I
P
D
L
K
R
D
K
V
V
I
L
D
R
F
V
L
S
T
I
A
Y
Q
G
Y
G
K
G
L
D
V
E
F
I
K
N
L
N
E
F
A
T
R
G
V
K
P
D
I
T
L
L
L
D
I
P
V
D
I
A
L
R
R
L
-----
K
E
K
N
R
--
F
E
N
K
E
F
L
E
K
V
R
K
G
F
L
E
L
A
K
E
-
E
E
N
V
V
V
I
-
D
A
-
S
G
E
E
E
E
V
F
K
E
I
L
R
A
L
S
G
V
L
R
----
41
PsiBlast_CBE
79.39
42%
-72
- C2 -
4EDH
4
KTHY_PSEAE
B:
[4-190]
M
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
20
PsiBlast_PDB
79.07
42%
-78
- C2 -
4ESH
1
KTHY_PSEAE
A:
[4-190]
M
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
----
G
--
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
19
PsiBlast_PDB
79.01
42%
-71
- C2 -
4EDH
5
KTHY_PSEAE
A:
[5-190]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
--
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
48
PsiBlast_CBE
78.49
42%
-74
- C2 -
3UXM
1
KTHY_PSEAE
B:
[1-186]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
----
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
45
PsiBlast_CBE
77.66
42%
-77
- C2 -
3UWK
2
KTHY_PSEAE
A:
[23-207]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
-----
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
42
PsiBlast_CBE
77.37
42%
-83
- C2 -
3UWO
1
KTHY_PSEAE
B:
[11-195]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
--------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
43
PsiBlast_CBE
77.31
42%
-81
- C2 -
3UWO
1
KTHY_PSEAE
A:
[11-195]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-------------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
46
PsiBlast_CBE
77.29
42%
-77
- C2 -
3UXM
1
KTHY_PSEAE
D:
[2-186]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
A
R
G
--
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
125
HHSearch
77.26
38%
-82
- C2 -
3V9P
5
KTHY_BURTA
A:
[24-226]
-
R
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
----
W
F
C
D
R
L
Q
E
R
L
G
P
A
G
R
-------
H
-
V
V
-
V
-
T
R
-
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
N
Q
-------------
P
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
V
R
--
M
P
---
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
-
D
S
-
S
E
P
I
A
Q
I
R
K
Q
L
E
G
V
L
A
A
-------
44
PsiBlast_CBE
77.23
42%
-81
- C2 -
3UWK
1
KTHY_PSEAE
B:
[23-207]
--
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
------------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
40
PsiBlast_CBE
76.87
42%
-79
- C2 -
4GMD
3
KTHY_PSEAE
A:
[5-190]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
-----
A
R
G
--
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
39
PsiBlast_CBE
76.09
42%
-78
- C2 -
4GMD
4
KTHY_PSEAE
B:
[5-190]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
--------------
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
37
PsiBlast_CBE
76.09
42%
-84
- C2 -
4GMD
4
KTHY_PSEAE
D:
[5-190]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
--------------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
38
PsiBlast_CBE
76.08
42%
-84
- C2 -
4GMD
3
KTHY_PSEAE
C:
[5-190]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
G
K
S
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
-------------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
52
PsiBlast_CBE
75.46
34%
-84
- C2 -
3LD9
2
KTHY_EHRCR
D:
[21-222]
--
S
M
F
I
T
F
E
G
I
D
G
S
G
K
T
T
---------
Q
S
H
L
L
A
E
----
Y
L
SEIYGVN
N
-
V
V
-
L
-
T
R
-
E
P
G
G
T
L
L
N
E
S
V
R
N
L
L
F
K
A
---
Q
---
G
------
L
D
S
L
S
E
L
L
F
F
I
A
M
R
R
E
H
F
V
K
I
I
K
P
S
L
M
Q
K
K
I
V
I
C
D
R
F
I
D
S
T
I
A
Y
Q
G
Y
G
Q
G
I
D
C
S
L
I
D
Q
L
N
D
L
V
I
-
D
V
Y
P
D
I
T
F
I
I
D
V
D
----------------------
D
M
E
F
Y
Y
R
V
R
D
G
F
Y
D
I
A
K
K
N
P
H
R
C
H
V
I
T-----
T
Y
D
--
I
D
D
I
N
F
V
H
L
E
V
I
K
V
L
Q
M
47
PsiBlast_CBE
75.10
42%
-77
- C2 -
3UXM
3
KTHY_PSEAE
C:
[1-186]
-
T
G
L
F
V
T
L
E
G
P
E
G
A
---
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
A
A
------
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------
54
PsiBlast_CBE
74.92
34%
-90
- C2 -
3LD9
2
KTHY_EHRCR
B:
[21-222]
--
S
M
F
I
T
F
E
G
I
D
G
S
G
K
T
T
---------
Q
S
H
L
L
A
E
----
Y
L
S
E
I
YGVN
N
-
V
V
-
L
-
T
R
-
E
P
G
G
T
L
L
N
E
S
V
R
N
L
L
F
K
A
---
Q
---
G
------
L
D
S
L
S
E
L
L
F
F
I
A
M
R
R
E
H
F
V
K
I
I
K
P
S
L
M
Q
K
K
I
V
I
C
D
R
F
I
D
S
T
I
A
Y
Q
G
Y
G
Q
G
I
D
C
S
L
I
D
Q
L
N
D
L
V
I
-
D
V
Y
P
D
I
T
F
I
I
D
V
-----------------------
D
M
E
F
Y
Y
R
V
R
D
G
F
Y
D
I
A
K
K
N
P
H
R
C
H
V
I
T
------------
D
I
N
F
V
H
L
E
V
I
K
V
L
Q
M
56
PsiBlast_CBE
74.90
39%
-79
- C2 -
3V9P
4
KTHY_BURTA
B:
[25-211]
--
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
R
L
G
P
A
----
G
R
-------
H
-
V
V
-
V
-
T
R
-
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
N
Q
---
P
----------
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
--
V
R
M
P
D
K
F
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
-
D
S
-
S
E
----------------------
57
PsiBlast_CBE
73.96
39%
-78
- C2 -
3V9P
5
KTHY_BURTA
A:
[25-211]
--
G
K
F
I
T
F
E
G
I
D
---
K
T
T
H
L
Q
W
F
C
D
R
L
Q
E
R
L
G
P
A
----
G
R
-------
H
-
V
V
-
V
-
T
R
-
E
P
G
G
T
R
L
G
E
T
L
R
E
I
L
L
N
Q
---
P
----------
M
D
L
E
T
E
A
L
L
M
F
A
G
R
R
E
H
L
A
L
V
I
E
P
A
L
A
R
G
D
W
V
V
S
D
R
F
T
D
A
T
F
A
Y
Q
G
G
G
R
G
L
P
R
D
K
L
E
A
L
E
R
W
V
Q
G
G
F
Q
P
D
L
T
V
L
F
D
V
P
P
Q
I
A
S
A
R
R
G
A
--
V
R
M
P
---
E
S
E
S
D
A
F
F
A
R
T
R
A
E
Y
L
R
R
A
Q
E
A
P
H
R
F
V
I
V
-
D
S
-
S
E
----------------------
49
PsiBlast_CBE
72.35
42%
-80
- C2 -
3UXM
3
KTHY_PSEAE
A:
[2-186]
--
G
L
F
V
T
L
E
G
P
E
G
----
T
N
R
D
----
Y
L
A
E
R
L
R
E
R
----
G
I
-------
E
-
V
Q
-
L
-
T
R
-
E
P
G
G
T
P
L
A
E
R
I
R
E
L
L
L
A
P
---
S
---
D
-
E
---
P
M
A
A
D
T
E
L
L
L
M
F
A
A
R
A
Q
H
L
A
G
V
I
R
P
A
L
A
R
G
A
V
V
L
C
D
R
F
T
D
A
T
Y
A
Y
Q
G
G
G
R
G
L
P
E
A
R
I
A
A
L
E
S
F
V
Q
G
D
L
R
P
D
L
T
L
V
F
D
L
P
V
E
I
G
L
A
R
-------
R
L
D
R
F
E
Q
E
D
R
R
F
F
E
A
V
R
Q
T
Y
L
Q
R
A
A
Q
A
P
E
R
Y
Q
V
L
-
D
A
-
G
-----------------------