@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1051: (2016-03-21 )
MLTMDDIVREGHPALREVATEVTFPLSDEEKKLGRDMLEFLINSQDEDLAEKYGLRGGVGIAAPQLAVTKRFLAIHVHDEKDRLYSYVLYNPKIRSHSVQQACLSGGEGCLSVDREVPGYVVRSERVTIDAFDENGTPLKLRFKGYPAIVIQHEIDHLNGIMFYDHINKENPSYLPPDVDVFG
Atome Classification :
(85 SA)
.........10........20..-..--....30........40........50........60........70......-..-80.-----.------.-------.-...--..90------....-.....100.......110.......120-.........130.......140.......150.......160.......170.......180.----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
T
M
D
D
I
V
REG
H
P
A
L
R
E
V
A
T
E
VT-FP--LS
D
E
E
K
K
L
G
R
D
M
L
E
F
L
INSQ
D
E
D
L
A
E
K
YGLRGGVGIAA
P
Q
L
A
V
T
K
R
F
L
A
I
H
V
-HD-E-K-----D------
R
-------
L
-
Y
S
Y
--
V
LY-------NPKI-RS
H
S
V
Q
Q
A
C
L
SGGEG
C
L
SVDREVP
G
Y
---
V
V
R
S
E
R
V
T
I
D
A
FDENG
T
P
L
K
L
R
FKG
Y
P
A
I
V
I
Q
H
EIDHLN
G
I
M
F
Y
DHINKENPSYLPPDVDVFG----
101
HHSearch
96.44
60%
-121
- C6 -
2OS0
2
DEF_ENTFA
A:
[1-187]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
-
V
P
--
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
K
N
S
Q
D
P
V
K
A
E
E
L
Q
L
R
G
D
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
-
P
-------------------------
S
-
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
---
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
A
L
K
E
G
V
L
V
I
E
----
8
PsiBlast_PDB
95.55
58%
-108
- C6 -
1LQW
1
DEF_STAAU
A:
[1-179]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
-
L
P
--
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
-
P
D
-
D
G
S
-----
G
------
K
-------
S
-
Y
D
Y
--
M
L
V
-------
N
P
K
I
-
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
---
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
--
L
Q
P
H
T
D
-------
4
PsiBlast_PDB
95.49
61%
-115
- C6 -
2OS1
5
DEF_ENTFA
A:
[1-179]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
-
V
P
--
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
K
N
S
Q
D
P
V
K
A
E
E
L
Q
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P------------------
S
-------
L
--
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
---
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
A
L
------------
24
PsiBlast_CBE
95.48
58%
-106
- C6 -
2AI9
2
DEF_STAAU
B:
[1-179]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
-
L
P
--
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
-
P
D
-
D
G
S
-----
G
------
K
-------
S
-
Y
D
Y
--
M
L
V
-------
N
P
K
I
-
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
---
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
--
L
Q
P
H
T
D
-------
104
HHSearch
95.22
60%
-101
- C6 -
2OKL
5
DEF2_BACCR
A:
[2-183]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
-
L
P
--
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
-
T
D
-
A
-
D
-----
G
------
T
-------
L
-
Y
S
H
--
A
L
F
-------
N
P
K
I
-
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
S
K
P
L
-----
9
PsiBlast_PDB
95.16
58%
-109
- C6 -
2AI9
2
DEF_STAAU
A:
[1-179]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
-
L
P
--
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
-
P
D
-
D
G
S
-----
G
------
K
-------
S
-
Y
D
Y
--
M
L
V
-------
N
P
K
I
-
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
---
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
--
L
Q
P
H
T
D
-------
23
PsiBlast_CBE
94.97
62%
-117
- C6 -
3CMD
7
?
B:
[10-188]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
-
L
P
--
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
-
P
S
------------------------
S
-
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
A
L
------------
22
PsiBlast_CBE
94.79
62%
-114
- C6 -
3G6N
5
?
B:
[5-183]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
-
L
P
--
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
-
P
S
------------------------
S
-
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
A
L
------------
25
PsiBlast_CBE
94.75
58%
-99
- C6 -
1LQW
1
DEF_STAAU
B:
[1-179]
M
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
-
L
P
--
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
-
P
D
-
D
G
S
-----
G
------
K
-------
S
-
Y
D
Y
--
M
L
V
-------
N
P
K
I
-
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
---
V
H
R
H
N
R
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
N
H
P
--
L
Q
P
H
T
D
-------
2
PsiBlast_PDB
94.74
62%
-115
- C6 -
3G6N
3
?
A:
[5-183]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
-
L
P
--
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
-
P
S
------------------------
S
-
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
A
L
------------
5
PsiBlast_PDB
94.08
58%
-104
- C6 -
1LQY
3
DEF2_GEOSE
A:
[1-176]
M
I
T
M
K
D
I
I
K
E
G
H
P
T
L
R
K
V
A
E
P
V
P
-
L
P
--
P
S
E
E
D
K
R
I
L
Q
S
L
L
D
Y
V
K
M
S
Q
D
P
E
L
A
A
K
Y
G
L
R
P
G
I
G
L
A
A
P
Q
I
N
V
S
K
R
M
I
A
V
H
V
-
T
D
-
E
-
N
-----
G
------
T
-------
L
-
Y
S
Y
--
A
L
F
-------
N
P
K
I
-
V
S
H
S
V
Q
Q
C
Y
L
T
T
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
---
V
L
R
Y
A
R
I
T
V
T
G
T
T
L
D
G
E
E
V
T
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
I
M
F
Y
D
R
I
N
P
A
D
P
F
Q
V
P
-----------
3
PsiBlast_PDB
94.05
62%
-115
- C6 -
3CMD
6
?
A:
[10-188]
M
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
E
V
A
K
E
V
S
-
L
P
--
L
S
E
E
D
I
S
L
G
K
E
M
L
E
F
L
K
N
S
Q
D
P
I
K
A
E
E
L
H
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
-
P
S
------------------------
S
-
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
A
C
L
G
E
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
V
R
H
A
K
I
T
V
S
Y
Y
D
M
N
G
E
K
H
K
I
R
L
K
N
Y
E
S
I
V
V
Q
H
E
I
D
H
I
N
G
V
M
F
Y
D
H
I
N
D
Q
N
P
F
A
L
------------
10
PsiBlast_PDB
94.03
58%
-102
- C6 -
2OS3
2
DEF_STRP1
A:
[12-192]
L
I
T
M
D
D
I
I
R
E
G
N
P
T
L
R
A
V
A
K
E
V
S
-
L
P
--
L
C
D
E
D
I
L
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
P
V
M
A
E
K
L
G
L
R
A
G
V
G
L
A
A
P
Q
I
D
V
S
K
R
I
I
A
V
L
V
-
P
N
-
L
-
P
-----
D
------
K
EGNPPKE
A
-
Y
S
W
Q
E
V
L
Y
-------
N
P
K
I
-
V
S
H
S
V
Q
D
A
A
L
S
D
G
E
G
C
L
S
V
D
R
V
V
E
G
Y
---
V
V
R
H
A
R
V
T
V
D
Y
Y
D
K
E
G
Q
Q
H
R
I
K
L
K
G
Y
N
A
I
V
V
Q
H
E
I
D
H
I
N
G
V
L
F
Y
D
R
I
N
A
K
N
P
---------------
21
PsiBlast_CBE
93.82
61%
-102
- C6 -
2OKL
4
DEF2_BACCR
B:
[2-179]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
-
L
P
--
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
-
T
D
-
A
-
D
-----
G
------
T
-------
L
-
Y
S
H
--
A
L
F
-------
N
P
K
I
-
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
---------
6
PsiBlast_PDB
93.68
60%
-116
- C6 -
2OS0
2
DEF_ENTFA
A:
[1-179]
M
I
T
M
K
D
I
I
R
E
G
N
P
T
L
R
A
V
A
E
E
V
P
-
V
P
--
I
T
E
E
D
R
Q
L
G
E
D
M
L
T
F
L
K
N
S
Q
D
P
V
K
A
E
E
L
Q
L
R
G
D
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
H
V
P---------------------------S
L
S
T
--
V
M
Y
-------
N
P
K
I
-
L
S
H
S
V
Q
D
V
C
L
G
E
G
E
G
C
L
S
V
D
R
D
V
P
G
Y
---
V
V
R
H
N
K
I
T
V
S
Y
F
D
M
A
G
E
K
H
K
V
R
L
K
N
Y
E
A
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
H
I
N
K
E
N
P
F
A
L
------------
14
PsiBlast_PDB
93.54
55%
-105
- C6 -
1LMH
1
DEF_STAAU
A:
[2-180]
-
L
T
M
K
D
I
I
R
D
G
H
P
T
L
R
Q
K
A
A
E
L
E
-
L
P
--
L
T
K
E
E
K
E
T
L
I
A
M
R
E
F
L
V
N
S
Q
D
E
E
I
A
K
R
Y
G
L
R
S
G
V
G
L
A
A
P
Q
I
N
I
S
K
R
M
I
A
V
L
I
-
P
D
-
D
G
S
-----
G
------
K
-------
S
-
Y
D
Y
--
M
L
V
-------
N
P
K
I
-
V
S
H
S
V
Q
E
A
Y
L
P
T
G
E
G
C
L
S
V
D
D
N
V
A
G
L
---
V
H
R
H
N
K
I
T
I
K
A
K
D
I
E
G
N
D
I
Q
L
R
L
K
G
Y
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
D
K
D
H
P
--
L
Q
P
H
T
D
A
------
1
PsiBlast_PDB
93.27
61%
-99
- C6 -
2OKL
5
DEF2_BACCR
A:
[2-179]
M
L
T
M
K
D
V
I
R
E
G
D
P
I
L
R
N
V
A
E
E
V
S
-
L
P
--
A
S
E
E
D
T
T
T
L
K
E
M
I
E
F
V
I
N
S
Q
D
P
E
M
A
E
K
Y
S
L
R
P
G
I
G
L
A
A
P
Q
I
G
V
S
K
K
M
I
A
V
H
V
-
T
D
-
A
-
D
-----
G
------
T
-------
L
-
Y
S
H
--
A
L
F
-------
N
P
K
I
-
I
S
H
S
V
E
R
T
Y
L
Q
G
G
E
G
C
L
S
V
D
R
E
V
P
G
Y
---
V
P
R
Y
T
R
I
T
V
K
A
T
S
I
N
G
E
E
V
K
L
R
L
K
G
L
P
A
I
V
F
Q
H
E
I
D
H
L
N
G
V
M
F
Y
D
H
I
N
K
E
N
P
F
A
A
P
D
D
---------
7
PsiBlast_PDB
91.47
57%
-108
- C6 -
3SW8
5
?
P:
[13-192]
L
I
D
M
N
D
I
I
R
E
G
N
P
T
L
R
T
V
A
E
E
V
T
-
F
P
--
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
-
P
N
I--
E
-----
A
------
Y
-------
D
-
L
E
A
--
I
M
Y
-------
N
P
K
I
-
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
---
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
---------------
12
PsiBlast_PDB
90.74
57%
-105
- C6 -
2AI7
3
DEF_STRR6
A:
[13-192]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
-
F
P
--
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
-
P
N
I--
E
-----
A
------
Y
-------
D
-
L
E
A
--
I
M
Y
-------
N
P
K
I
-
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
---
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
---------------
13
PsiBlast_PDB
90.46
57%
-108
- C6 -
2AIA
3
DEF_STRR6
A:
[13-192]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
-
F
P
--
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
-
P
N
---------
A
------
Y
-------
D
-
L
E
A
--
I
M
Y
-------
N
P
K
I
-
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
---
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
---------------
11
PsiBlast_PDB
90.41
57%
-106
- C6 -
2AIE
3
DEF_STRR6
P:
[13-192]
L
I
D
M
C
D
I
I
R
E
G
N
P
S
L
R
T
V
A
E
E
V
T
-
F
P
--
L
S
D
Q
E
I
I
L
G
E
K
M
M
Q
F
L
K
H
S
Q
D
P
V
M
A
E
K
M
G
L
R
G
G
V
G
L
A
A
P
Q
L
D
I
S
K
R
I
I
A
V
L
V
-
P
N
I--
E
-----
A
------
Y
-------
D
-
L
E
A
--
I
M
Y
-------
N
P
K
I
-
V
S
H
S
V
Q
D
A
A
L
G
E
G
E
G
C
L
S
V
D
R
N
V
P
G
Y
---
V
V
R
H
A
R
V
T
V
D
Y
F
D
K
D
G
E
K
H
R
I
K
L
K
G
Y
N
S
I
V
V
Q
H
E
I
D
H
I
N
G
I
M
F
Y
D
R
I
N
E
K
D
P
---------------
103
HHSearch
77.85
33%
-84
- C6 -
3U04
4
?
A:
[3-183]
-
M
S
V
L
S
I
V
T
V
P
D
K
R
L
S
L
C
S
E
E
V
E
--
K
--
V
D
Q
S
I
R
K
L
V
D
D
M
F
E
T
M
--
H
A
----------
N
Q
G
L
G
L
A
A
V
Q
V
G
V
H
K
R
I
L
V
M
N
V
-
P
E
-
E
--------IEGYEL
Y
-------
G
-
G
P
Y
--
C
I
I
-------
N
P
K
I
-
V
D
I
S
Q
E
--
K
V
K
L
K
E
G
C
L
S
V
P
G
Y
F
D
-
Y
---
I
V
R
P
Q
R
I
A
V
Q
Y
L
D
Y
N
G
N
E
C
I
I
K
A
Q
G
W
L
A
R
C
L
Q
H
E
I
D
H
L
N
G
T
V
F
L
K
Y
L
S
K
F
K
R
D
F
A
I
E
K
V
K
K
------
107
HHSearch
75.05
33%
-76
- C6 -
1Y6H
5
DEF_LEPIN
A:
[1-170]
--
S
V
R
K
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
E
D
E
I-
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
--
R
H
----------
A
E
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
RYPG
T
P
------
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
--
T
S
G
F
W
E
G
C
L
S
V
P
G
M
R
G
-
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
D
T
K
L
F
G
F
N
E
T
L
D
-------
39
PsiBlast_CBE
74.62
31%
-101
- C6 -
1Y6H
5
DEF_LEPIN
A:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPG
T
P
-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
43
PsiBlast_CBE
74.39
31%
-101
- C6 -
1VEY
2
DEF_LEPIN
A:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
E
I
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGT
P
-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
46
PsiBlast_CBE
74.10
31%
-99
- C6 -
1SV2
3
DEF_LEPIN
B:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
38
PsiBlast_CBE
73.86
31%
-94
- C6 -
1Y6H
6
DEF_LEPIN
B:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
44
PsiBlast_CBE
73.83
31%
-99
- C6 -
1VEV
3
DEF_LEPIN
B:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
42
PsiBlast_CBE
73.68
31%
-98
- C6 -
1VEY
2
DEF_LEPIN
B:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
47
PsiBlast_CBE
73.53
31%
-98
- C6 -
1SV2
2
DEF_LEPIN
A:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
E
I
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
45
PsiBlast_CBE
73.46
31%
-96
- C6 -
1VEV
4
DEF_LEPIN
A:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
E
I
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
41
PsiBlast_CBE
73.13
31%
-97
- C6 -
1VEZ
9
DEF_LEPIN
A:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
E
I
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
40
PsiBlast_CBE
72.92
31%
-96
- C6 -
1VEZ
8
DEF_LEPIN
B:
[5-158]
------
I
L
R
M
G
D
P
I
L
R
K
I
S
E
P
V
T
-
E
D
EI
Q
T
K
E
F
K
K
L
I
R
D
M
F
D
T
M
R
H
A
E
------------
G
V
G
L
A
A
P
Q
I
G
I
L
K
Q
I
V
V
V
G
S
-
E
D
-
N
-
E
-----
R
YPGTP-
D
-------
V
-
P
E
R
--
I
I
L
-------
N
P
V
I
-
T
P
L
T
K
D
T
S
G
F
--
W
E
G
C
L
S
V
P
-
G
M
R
G
Y
---
V
E
R
P
N
Q
I
R
M
Q
W
M
D
E
K
G
N
Q
F
D
E
T
I
D
G
Y
K
A
I
V
Y
Q
H
E
C
D
H
L
Q
G
I
L
Y
V
D
R
L
K
-------------------
127
Fugue
72.62
32%
-81
- C6 -
1G2A
2
DEF_ECOLI
A:
[1-164]
--
S
V
L
Q
V
L
H
I
P
D
E
R
L
R
K
V
A
K
P
V
E
--
E
--
V
N
A
E
I
Q
R
I
V
D
D
M
F
E
T
M
Y
A
E
------------
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
---
I
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
P
L
K
Q
Q
R
I
R
Q
K
V
E
K
L
D
R
L--
31
PsiBlast_CBE
71.98
35%
-102
- C6 -
4DR8
2
?
C:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
27
PsiBlast_CBE
71.82
35%
-104
- C6 -
4DR9
2
?
D:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
YLD
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
30
PsiBlast_CBE
71.75
35%
-103
- C6 -
4DR8
2
?
D:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
YLD
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
17
PsiBlast_PDB
71.50
35%
-102
- C6 -
4DR8
3
?
A:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
16
PsiBlast_PDB
71.37
35%
-107
- C6 -
4DR9
2
?
A:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
--------------------------
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
28
PsiBlast_CBE
71.29
35%
-106
- C6 -
4DR9
3
?
C:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
29
PsiBlast_CBE
71.18
35%
-101
- C6 -
4DR9
3
?
B:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
32
PsiBlast_CBE
70.97
35%
-98
- C6 -
4DR8
4
?
B:
[25-165]
----------
G
D
R
V
L
R
Q
P
A
K
R
V
S
-
R
---
I
D
D
E
L
R
Q
T
I
R
Q
M
L
Q
T
M
Y
S
A
D
------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
Q
L
I
V
I
D
L
-
E
L
-
E
-
D
-----
E
------
Q
-------
A
-
P
P
L
--
V
L
I
-------
N
P
K
I
E
R
T
A
G
D
L
E
Q
C
---
Q
E
G
C
L
S
I
----
P
G
V
Y
L
D
V
E
R
P
E
I
V
E
V
S
Y
K
D
E
N
G
R
P
Q
R
L
V
A
D
G
L
L
A
R
C
I
Q
H
E
M
D
H
L
N
G
V
L
F
V
D
R
V
--------------------
106
HHSearch
70.72
34%
-77
- C6 -
3UWB
4
?
A:
[2-150]
---
S
L
K
I
K
T
I
G
D
R
C
L
R
Q
K
S
E
E
V
E
-
F
---
D
K
K
E
M
S
E
L
Y
D
Q
M
C
E
A
M
--
W
A
----------
S
D
G
I
G
L
A
A
P
Q
V
G
I
N
K
R
V
I
V
V
D
E
-
T
T
-
E
-
E
-----
H
------
G
-------
K
-
Y
A
H
--
L
M
V
-------
N
P
K
I
-
T
W
K
S
E
E
--
K
V
L
F
D
E
G
C
L
S
V
P
D
Q
N
G
-
E
---
V
L
R
P
K
S
I
K
V
T
F
Q
N
K
D
G
K
Y
K
K
W
K
L
D
G
L
A
A
R
V
V
Q
H
E
I
D
H
L
E
G
I
L
F
V
D
Y
F
N
-------------------
126
Fugue
70.53
33%
-83
- C6 -
1G2A
2
DEF_ECOLI
A:
[1-164]
--
S
V
L
Q
V
L
H
I
P
D
E
R
L
R
K
V
A
K
P
V
E
--
E
--
V
N
A
E
I
Q
R
I
V
D
D
M
F
E
T
M
Y
A
E
------------
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
S-
E
-
N
-
R
-----
D
----------------
E
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
---
G
E
T
G
I
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
--
P
L
K
Q
Q
R
I
R
Q
K
V
E
K
L
D
R
L
108
HHSearch
70.14
31%
-73
- C6 -
1N5N
3
DEF_PSEAE
A:
[13-172]
-
M
A
I
L
N
I
L
E
F
P
D
P
R
L
R
T
I
A
K
P
V
E
--
V
--
V
D
D
A
V
R
Q
L
I
D
D
M
F
E
T
M
--
Y
E
----------
A
P
G
I
G
L
A
A
T
Q
V
N
V
H
K
R
I
V
V
M
D
L
-
S
E
-
D
--------------
K
-------
S
-
E
P
R
--
V
F
I
-------
N
P
E
F
-
E
P
L
T
E
E
--
M
D
Q
Y
Q
E
G
C
L
S
V
P
G
F
Y
E
-
N
---
V
D
R
P
Q
K
V
R
I
K
A
L
D
R
D
G
N
P
F
E
E
V
A
E
G
L
L
A
V
C
I
Q
H
E
C
D
H
L
N
G
K
L
F
V
D
Y
L
S
T
L
K
R
D
R
I
R
K
K
L
--------
118
HHSearch
69.28
31%
-81
- C6 -
1RL4
3
?
A:
[10-170]
-----
K
I
V
K
Y
P
D
P
I
L
R
R
R
S
E
E
V
T
--
N
--
F
D
D
N
L
K
R
V
V
R
K
M
F
D
I
M
--
Y
E
----------
S
K
G
I
G
L
S
A
P
Q
V
N
I
S
K
R
I
I
V
W
N
--------------------------------
R
--
I
F
I
-------
N
P
S
I
-
V
E
Q
S
L
V
--
K
L
K
L
I
E
G
C
L
S
F
P
G
I
E
G
-
K
---
V
E
R
P
S
I
V
S
I
S
Y
Y
D
I
N
G
Y
K
H
L
K
I
L
K
G
I
H
S
R
I
F
Q
H
E
F
D
H
L
N
G
T
L
F
I
D
K
M
T
Q
V
D
K
K
K
V
R
P
K
L
N
E
------
105
HHSearch
69.03
32%
-69
- C6 -
1XEO
2
DEF_ECOLI
A:
[1-158]
--
S
V
L
Q
V
L
H
I
P
D
E
R
L
R
K
V
A
K
P
V
E
--
E
--
V
N
A
E
I
Q
R
I
V
D
D
M
F
E
T
M
--
Y
A
----------
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
--------------------
D
-
E
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
---
T
G
I
E
E
G
C
L
S
I
P
E
Q
R
A
-
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
P
L
K
Q
Q
R
I
R
Q
K
V
--------
110
HHSearch
68.95
32%
-74
- C6 -
2W3T
3
DEF_ECOLI
A:
[1-158]
--
S
V
L
Q
V
L
H
I
P
D
E
R
L
R
K
V
A
K
P
V
E
--
E
--
V
N
A
E
I
Q
R
I
V
D
D
M
F
E
T
M
--
Y
A
----------
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
--------------------
D
-
E
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
---
T
G
I
E
E
G
C
L
S
I
P
E
Q
R
A
-
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
P
L
K
Q
Q
R
I
R
Q
K
V
--------
68
PsiBlast_CBE
67.39
36%
-105
- C6 -
1G2A
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
70
PsiBlast_CBE
67.21
36%
-107
- C6 -
1G27
2
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
52
PsiBlast_CBE
67.18
36%
-107
- C6 -
3K6L
2
DEF_ECOLI
B:
[33-148]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
50
PsiBlast_CBE
67.17
36%
-101
- C6 -
2W3T
3
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
36
PsiBlast_CBE
67.02
36%
-107
- C6 -
4AL2
2
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
37
PsiBlast_CBE
66.99
36%
-102
- C6 -
4AL2
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
63
PsiBlast_CBE
66.89
36%
-102
- C6 -
1ICJ
3
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
90
PsiBlast_CBE
66.79
36%
-102
- C6 -
1BS4
3
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
49
PsiBlast_CBE
66.61
36%
-95
- C6 -
2W3U
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
89
PsiBlast_CBE
66.58
36%
-103
- C6 -
1BS4
3
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
73
PsiBlast_CBE
66.53
36%
-103
- C6 -
1BSZ
3
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
77
PsiBlast_CBE
66.35
36%
-102
- C6 -
1BS8
3
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
57
PsiBlast_CBE
66.32
36%
-99
- C6 -
1XEO
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
72
PsiBlast_CBE
66.26
36%
-101
- C6 -
1BSZ
3
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
35
PsiBlast_CBE
66.22
36%
-106
- C6 -
4AL2
2
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
74
PsiBlast_CBE
66.18
36%
-98
- C6 -
1BSZ
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
83
PsiBlast_CBE
66.12
36%
-102
- C6 -
1BS6
3
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
69
PsiBlast_CBE
66.12
36%
-101
- C6 -
1G27
2
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
59
PsiBlast_CBE
66.12
36%
-99
- C6 -
1XEM
11
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
58
PsiBlast_CBE
66.09
36%
-98
- C6 -
1XEN
6
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
85
PsiBlast_CBE
65.98
36%
-101
- C6 -
1BS6
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
84
PsiBlast_CBE
65.86
36%
-104
- C6 -
1BS6
3
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
67
PsiBlast_CBE
65.85
36%
-99
- C6 -
1G2A
2
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
65
PsiBlast_CBE
65.82
36%
-98
- C6 -
1ICJ
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
60
PsiBlast_CBE
65.65
36%
-105
- C6 -
1LRU
2
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
56
PsiBlast_CBE
65.56
36%
-97
- C6 -
2AI8
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
54
PsiBlast_CBE
65.50
36%
-102
- C6 -
2AI8
2
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
91
PsiBlast_CBE
65.49
36%
-100
- C6 -
1BS4
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
79
PsiBlast_CBE
65.37
36%
-99
- C6 -
1BS8
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
53
PsiBlast_CBE
65.22
36%
-101
- C6 -
3K6L
2
DEF_ECOLI
A:
[33-148]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
62
PsiBlast_CBE
65.06
36%
-97
- C6 -
1LRU
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
71
PsiBlast_CBE
65.05
36%
-108
- C6 -
1G27
2
DEF_ECOLI
A:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
34
PsiBlast_CBE
64.97
35%
-102
- C6 -
3U04
4
?
A:
[35-171]
-------------------------------------------------
D
D
M
F
E
T
M
H
A
N
Q
G
L
G
L
A
A
V
Q
V
G
V
H
K
R
I
L
V
M
N
V
-
P
E
-
E
----------------------
I
-
E
G
Y
--
E
L
Y
GGP
Y
C
I
I
N
P
K
I
-
V
D
I
S
Q
E
K
V
K
L
K
--
E
G
C
L
S
V
----
P
G
Y
F
D
Y
I
V
R
P
Q
R
I
A
V
Q
Y
L
D
Y
N
G
N
E
C
I
I
K
A
Q
G
W
L
A
R
C
L
Q
H
E
I
D
H
L
N
G
T
V
F
L
K
Y
L
S
K
------------------
55
PsiBlast_CBE
64.77
36%
-97
- C6 -
2AI8
2
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
66
PsiBlast_CBE
64.76
36%
-99
- C6 -
1G2A
2
DEF_ECOLI
C:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
61
PsiBlast_CBE
63.79
36%
-99
- C6 -
1LRU
3
DEF_ECOLI
B:
[32-147]
-------------------------------------------------
D
D
M
F
E
T
M
Y
A
E
E
G
I
G
L
A
A
T
Q
V
D
I
H
Q
R
I
I
V
I
D
V
-
S
E
-
N
-
R
-----
D
------
E
----------
R
L
--
V
L
I
-------
N
P
E
L
-
L
E
K
S
G
E
T
G
I
---
E
E
G
C
L
S
I
P
-
E
Q
R
A
L
---
V
P
R
A
E
K
V
K
I
R
A
L
D
R
D
G
K
P
F
E
L
E
A
D
G
L
L
A
I
C
I
Q
H
E
M
D
H
L
V
G
K
L
F
M
D
Y
L
S
-------------------
19
PsiBlast_PDB
61.16
38%
-98
- C6 -
3UWB
4
?
A:
[43-150]
------------------------------------------------------------
G
I
G
L
A
A
P
Q
V
G
I
N
K
R
V
I
V
V
D
E
-
T
T
-
E
-
E
-----
H
------
G
-------
K
-
Y
A
H
--
L
M
V
-------
N
P
K
I
-
T
W
K
S
E
E
K
V
L
F
D
--
E
G
C
L
S
V
P
D
Q
-
N
G
E
---
V
L
R
P
K
S
I
K
V
T
F
Q
N
K
D
G
K
Y
K
K
W
K
L
D
G
L
A
A
R
V
V
Q
H
E
I
D
H
L
E
G
I
L
F
V
D
Y
F
N
-------------------